acetoaminophenol (BioDeep_00000411661)

natural product

代谢物信息卡片

N-(2-Hydroxyphenyl)acetamide

化学式: C8H9NO2 (151.0633)
中文名称: 2-乙酰氨基苯酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)NC1=C(O)C=CC=C1
InChI: InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2697; ORIGINAL_PRECURSOR_SCAN_NO 2695
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2693; ORIGINAL_PRECURSOR_SCAN_NO 2690
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2673; ORIGINAL_PRECURSOR_SCAN_NO 2671
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2686; ORIGINAL_PRECURSOR_SCAN_NO 2684
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 2692; ORIGINAL_PRECURSOR_SCAN_NO 2689
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4204; ORIGINAL_PRECURSOR_SCAN_NO 4203
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4211; ORIGINAL_PRECURSOR_SCAN_NO 4209
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4223; ORIGINAL_PRECURSOR_SCAN_NO 4221
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4232; ORIGINAL_PRECURSOR_SCAN_NO 4231
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4241; ORIGINAL_PRECURSOR_SCAN_NO 4238
CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4220; ORIGINAL_PRECURSOR_SCAN_NO 4218
DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4220; CONFIDENCE standard compound; INTERNAL_ID 695; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; ORIGINAL_PRECURSOR_SCAN_NO 4218

同义名列表

3 个代谢物同义名

2-Acetamidophenol; acetoaminophenol; N-(2-Hydroxyphenyl)acetamide

数据库引用编号

19 个数据库交叉引用编号

ChEBI: CHEBI:143107
ChEBI: CHEBI:88870
PubChem: 11972
ChEMBL: CHEMBL1456301
CAS: 57047-65-1
CAS: 614-80-2
MoNA: LU069556
MoNA: LU069555
MoNA: LU069554
MoNA: LU069553
MoNA: LU069552
MoNA: LU069551
MoNA: LU069506
MoNA: LU069505
MoNA: LU069504
MoNA: LU069503
MoNA: LU069502
MoNA: LU069501
MoNA: CCMSLIB00005721076

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

355589 - Huperzia serrata: 10.1007/S10600-011-9991-4
67385 - Streptomyces xanthophaeus: 10.1080/14786419.2016.1269100

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Rehan Ahmed Siddiqui, Shabana Usman Simjee, Nurul Kabir, Muhammad Ateeq, M Raza Shah, Syed Saad Hussain. N-(2-hydroxyphenyl)acetamide and its gold nanoparticle conjugation prevent glycerol-induced acute kidney injury by attenuating inflammation and oxidative injury in mice. Molecular and cellular biochemistry. 2019 Jan; 450(1-2):43-52. doi: 10.1007/s11010-018-3371-3. [PMID: 29790115]
Kati Hanhineva, Pekka Keski-Rahkonen, Jenni Lappi, Kati Katina, Jenna Pekkinen, Otto Savolainen, Oskari Timonen, Jussi Paananen, Hannu Mykkänen, Kaisa Poutanen. The postprandial plasma rye fingerprint includes benzoxazinoid-derived phenylacetamide sulfates. The Journal of nutrition. 2014 Jul; 144(7):1016-22. doi: 10.3945/jn.113.187237. [PMID: 24812068]
Kahkashan Perveen, Farina Hanif, Huma Jawed, Shabana U Simjee. Protective efficacy of N-(2-hydroxyphenyl) acetamide against adjuvant-induced arthritis in rats. BioMed research international. 2013; 2013(?):635143. doi: 10.1155/2013/635143. [PMID: 23971042]
Huma Jawed, Syed Uzair Ali Shah, Siddiqua Jamall, Shabana Usman Simjee. N-(2-hydroxy phenyl) acetamide inhibits inflammation-related cytokines and ROS in adjuvant-induced arthritic (AIA) rats. International immunopharmacology. 2010 Aug; 10(8):900-5. doi: 10.1016/j.intimp.2010.04.028. [PMID: 20452462]
Mona Knop, Svea Pacyna, Nataliya Voloshchuk, Sandra Kant, Carmen Müllenborn, Ulrike Steiner, Martin Kirchmair, Heinrich W Scherer, Margot Schulz. Zea mays: benzoxazolinone detoxification under sulfur deficiency conditions--a complex allelopathic alliance including endophytic Fusarium verticillioides. Journal of chemical ecology. 2007 Feb; 33(2):225-37. doi: 10.1007/s10886-006-9226-5. [PMID: 17200890]
Chunhong Jia, Chunghong Jia, Per Kudsk, Solvejg K Mathiassen. Joint action of benzoxazinone derivatives and phenolic acids. Journal of agricultural and food chemistry. 2006 Feb; 54(4):1049-57. doi: 10.1021/jf051156r. [PMID: 16478216]
Yasushi Hori, Manami Fujisawa, Kenji Shimada, Yasuo Hirose, Toshiharu Yoshioka. Method for screening and quantitative determination of serum levels of salicylic Acid, acetaminophen, theophylline, phenobarbital, bromvalerylurea, pentobarbital, and amobarbital using liquid chromatography/electrospray mass spectrometry. Biological & pharmaceutical bulletin. 2006 Jan; 29(1):7-13. doi: 10.1248/bpb.29.7. [PMID: 16394500]
M Hamilton, P T Kissinger. The metabolism of 2- and 3-hydroxyacetanilide. Determination of metabolic products by liquid chromatography/electrochemistry. Drug metabolism and disposition: the biological fate of chemicals. 1986 Jan; 14(1):5-12. doi: . [PMID: 2868865]
R B Markham, P W Stashak, B Prescott, D F Amsbaugh, P J Baker. Effect of concanavalin A on lymphocyte interactions involved in the antibody response to type III pneumococcal polysaccharide I. Comparison of the suppression induced by con A and low dose paralysis. Journal of immunology (Baltimore, Md. : 1950). 1977 Mar; 118(3):952-6. doi: NULL. [PMID: 15032]
A Noma, K Nakayama. Polarographic method for rapid microdetermination of cholesterol with cholesterol esterase and cholesterol oxidase. Clinical chemistry. 1976 Mar; 22(3):336-40. doi: 10.1093/clinchem/22.3.336. [PMID: 3294]
P Szylman, O S Better, C Chaimowitz, A Rosler. Role of hyperkalemia in the metabolic acidosis of isolated hypoaldosteronism. The New England journal of medicine. 1976 Feb; 294(7):361-5. doi: 10.1056/nejm197602122940703. [PMID: 1674]
H Hidai, H Fujii, K Otsuka, K Abe, N Shimizu. Cushing's syndrome due to huge adrenocortical multinodular hyperplasia. Endocrinologia japonica. 1975 Dec; 22(6):555-60. doi: 10.1507/endocrj1954.22.555. [PMID: 182475]