Erythromycin propionate (BioDeep_00000410534)

   


代谢物信息卡片


erythromycin A 2-propanoate

化学式: C40H71NO14 (789.4874305999999)
中文名称: 红霉素丙酸酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(=O)OC1C(O[C@@H]2C(C)[C@H](OC3CC(C)(OC)[C@H](O)[C@@H](C)O3)[C@@H](C)C(=O)OC(CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@]2(C)O)OC(C)CC1N(C)C
InChI: InChI=1S/C40H71NO14/c1-15-27-40(11,48)33(44)22(5)30(43)20(3)18-38(9,47)35(55-37-32(53-28(42)16-2)26(41(12)13)17-21(4)50-37)23(6)31(24(7)36(46)52-27)54-29-19-39(10,49-14)34(45)25(8)51-29/h20-27,29,31-35,37,44-45,47-48H,15-19H2,1-14H3/t20-,21-,22+,23+,24-,25+,26+,27-,29+,31+,32-,33-,34+,35-,37+,38-,39-,40-/m1/s1

描述信息

C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic
Origin: Microbe

同义名列表

2 个代谢物同义名

erythromycin A 2-propanoate; Erythromycin propionate



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Li-qing Wang, Zhe-yi Hu, Qi Yu, Xin Guo, Jing Xiong, Zhi-zhuang Huang, Ze-neng Cheng. [Pharmacokinetics of erythromycin stinoprate capsule]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2005 Apr; 30(2):197-201. doi: NULL. [PMID: 15898434]
  • Weitao Xiao, Bo Chen, Shouzhuo Yao, Zeneng Cheng. Simultaneous determination of erythromycin propionate and base in human plasma by high-performance liquid chromatography-electrospray mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Mar; 817(2):153-8. doi: 10.1016/j.jchromb.2004.11.055. [PMID: 15686979]
  • C Stubbs, I Kanfer. High-performance liquid chromatography of erythromycin propionyl ester and erythromycin base in biological fluids. Journal of chromatography. 1988 May; 427(1):93-101. doi: 10.1016/0378-4347(88)80107-5. [PMID: 3410906]
  • W L Hand, N L King-Thompson, J D Johnson. Influence of bacterial-antibiotic interactions on subsequent antimicrobial activity of alveolar macrophages. The Journal of infectious diseases. 1984 Feb; 149(2):271-6. doi: 10.1093/infdis/149.2.271. [PMID: 6699436]
  • M Ducci, V Scalori, M del Tacca, G Soldani, C Bernardini, E Grothe, A Bertelli. The pharmacokinetics of two erythromycin esters in plasma and in saliva following oral administration in humans. International journal of clinical pharmacology, therapy, and toxicology. 1981 Nov; 19(11):494-7. doi: NULL. [PMID: 7298242]
  • K Y Tserng, J G Wagner. Fluorometric determination of erythromycin and erythromycin propionate in whole blood or plasma and correlation of results with microbiological assay. Analytical chemistry. 1976 Feb; 48(2):348-53. doi: 10.1021/ac60366a033. [PMID: 1247163]
  • H A BLOUGH, W H HALL, L HONG. Serum levels and clinical results with erythromycin propionate. The American journal of the medical sciences. 1960 May; 239(?):539-47. doi: 10.1097/00000441-196005000-00002. [PMID: 13801645]
  • H A HIRSCH, C M KUNIN, M FINLAND. Antibacterial activity of serum of normal men after oral doses of erythromycin propionate and triacetyloleandomycin. The New England journal of medicine. 1959 Feb; 260(9):408-12. doi: 10.1056/nejm195902262600902. [PMID: 13632901]