Thromboxane B3 (BioDeep_00000409904)

Main id: BioDeep_00000019036

 


代谢物信息卡片


(5E)-7-{4,6-dihydroxy-2-[(1E,5E)-3-hydroxyocta-1,5-dien-1-yl]oxan-3-yl}hept-5-enoic acid

化学式: C20H32O6 (368.2198772)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(lipidomics) 87.5%

分子结构信息

SMILES: C([C@H]1[C@@H](O)CC(O)O[C@@H]1/C=C/[C@@H](O)C/C=C\CC)/C=C\CCCC(=O)O
InChI: InChI=1S/C20H32O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h3-4,6-7,12-13,15-18,20-22,25H,2,5,8-11,14H2,1H3,(H,23,24)/b6-3+,7-4+,13-12+

描述信息

A member of the class of thromboxanes B that is (5Z,13E,17Z)-thromboxa-5,13,17-trien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.
CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0072.mzML; PROCESSING averaging of repeated ion fragments at 20.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ]
CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001323.mzML; PROCESSING averaging of repeated ion fragments at 20.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ]
CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001323.mzML; PROCESSING averaging of repeated ion fragments at 30.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ]
CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001323.mzML; PROCESSING averaging of repeated ion fragments at 40.0 NCE within 5 ppm window [MS, MS:1000575, mean of spectra, ]
CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001323.mzML; PROCESSING averaging of repeated ion fragments at 20.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ]
CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001323.mzML; PROCESSING averaging of repeated ion fragments at 30.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ]
CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0072.mzML; PROCESSING averaging of repeated ion fragments at 30.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ]
CONFIDENCE standard compound; NATIVE_RUN_ID STD_neg_MSMS_1min0072.mzML; PROCESSING averaging of repeated ion fragments at 10.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ]
CONFIDENCE standard compound; NATIVE_RUN_ID QExHF03_NM_0001323.mzML; PROCESSING averaging of repeated ion fragments at 10.0 eV within 5 ppm window [MS, MS:1000575, mean of spectra, ]

同义名列表

5 个代谢物同义名

Thromboxane B3; 9S,11,15S-trihydroxy-thromboxa-5Z,13E,17Z-trien-1-oic acid; FA 20:4;O4; TXB3; (5E)-7-{4,6-dihydroxy-2-[(1E,5E)-3-hydroxyocta-1,5-dien-1-yl]oxan-3-yl}hept-5-enoic acid



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jiaomei Li, Zhaohong Zheng, Min Liu, Yiping Ren, Yue Ruan, Duo Li. Relationship between the n-3 index, serum metabolites and breast cancer risk. Food & function. 2021 Sep; 12(17):7741-7748. doi: 10.1039/d1fo01245b. [PMID: 34296713]
  • Nobuaki Tanaka, Hiroaki Yamaguchi, Nariyasu Mano. Transport of eicosapentaenoic acid-derived PGE₃, PGF(3α), and TXB₃ by ABCC4. PloS one. 2014; 9(10):e109270. doi: 10.1371/journal.pone.0109270. [PMID: 25275481]
  • M E McCann, J N Moore, J B Carrick, M H Barton. Effect of intravenous infusion of omega-3 and omega-6 lipid emulsions on equine monocyte fatty acid composition and inflammatory mediator production in vitro. Shock (Augusta, Ga.). 2000 Aug; 14(2):222-8. doi: 10.1097/00024382-200014020-00024. [PMID: 10947170]
  • P Mayser, U Mrowietz, P Arenberger, P Bartak, J Buchvald, E Christophers, S Jablonska, W Salmhofer, W B Schill, H J Krämer, E Schlotzer, K Mayer, W Seeger, F Grimminger. Omega-3 fatty acid-based lipid infusion in patients with chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, multicenter trial. Journal of the American Academy of Dermatology. 1998 Apr; 38(4):539-47. doi: 10.1016/s0190-9622(98)70114-8. [PMID: 9555791]
  • J D Sørensen, S F Olsen, A K Pedersen, J Boris, N J Secher, G A FitzGerald. Effects of fish oil supplementation in the third trimester of pregnancy on prostacyclin and thromboxane production. American journal of obstetrics and gynecology. 1993 Mar; 168(3 Pt 1):915-22. doi: 10.1016/s0002-9378(12)90845-5. [PMID: 8456902]
  • G Honstra, A C van Houwelingen, G A Kivits, S Fischer, W Uedelhoven. Influence of dietary fish on eicosanoid metabolism in man. Prostaglandins. 1990 Sep; 40(3):311-29. doi: 10.1016/0090-6980(90)90018-q. [PMID: 2123355]
  • T Hamazaki, S Fischer, H Schweer, C O Meese, M Urakaze, A Yokoyama, S Yano. The infusion of trieicosapentaenoyl-glycerol into humans and the in vivo formation of prostaglandin I3 and thromboxane A3. Biochemical and biophysical research communications. 1988 Mar; 151(3):1386-94. doi: 10.1016/s0006-291x(88)80516-3. [PMID: 3281674]
  • S Fischer, P C Weber, J Dyerberg. The prostacyclin/thromboxane balance is favourably shifted in Greenland Eskimos. Prostaglandins. 1986 Aug; 32(2):235-41. doi: 10.1016/0090-6980(86)90128-0. [PMID: 3025932]
  • T Hirai, M Fujisaki, M Igarashi, T Asada, T Shiba, S Takeuchi, R Yamaguchi, T Shirai, M Kayama. Analysis of thromboxane B3 converted from eicosapentaenoic acid in human platelet rich plasma by gas chromatography/mass spectrometry. Thrombosis research. 1986 Mar; 41(5):637-47. doi: 10.1016/0049-3848(86)90360-9. [PMID: 3008371]