bemetizide (BioDeep_00000408897)
代谢物信息卡片
化学式: C15H16ClN3O4S2 (401.0270726)
中文名称: 贝美噻嗪
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: c(c3)ccc(c3)C(C)C(N1)NS(=O)(=O)c(c2)c(cc(Cl)c2S(N)(=O)=O)1
InChI: InChI=1S/C15H16ClN3O4S2/c1-9(10-5-3-2-4-6-10)15-18-12-7-11(16)13(24(17,20)21)8-14(12)25(22,23)19-15/h2-9,15,18-19H,1H3,(H2,17,20,21)
描述信息
C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic
同义名列表
1 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:135640
- PubChem: 72070
- ChEMBL: CHEMBL2104003
- CAS: 1824-52-8
- MoNA: WA001815
- MoNA: WA001814
- MoNA: WA001813
- MoNA: WA001812
- MoNA: WA001811
- MoNA: WA001810
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Bodaballa Avinash, Ravipati Venu, Tollamadugu N V K V Prasad, Mekapogu Alpha Raj, Kothapalli Srinivasa Rao, Chintamaneni Srilatha. Synthesis and characterisation of neem leaf extract, 2, 3-dehydrosalanol and quercetin dihydrate mediated silver nano particles for therapeutic applications.
IET nanobiotechnology.
2017 Jun; 11(4):383-389. doi:
10.1049/iet-nbt.2016.0095. [PMID: 28530186] - Jochen Beyer, Anabelle Bierl, Frank T Peters, Hans H Maurer. Screening procedure for detection of diuretics and uricosurics and/or their metabolites in human urine using gas chromatography-mass spectrometry after extractive methylation.
Therapeutic drug monitoring.
2005 Aug; 27(4):509-20. doi:
10.1097/01.ftd.0000160719.96445.91. [PMID: 16044110] - W Mühlberg, E Mutschler, A Hofner, H Spahn-Langguth, O Arnold. The influence of age on the pharmacokinetics and pharmacodynamics of bemetizide and triamterene: a single and multiple dose study.
Archives of gerontology and geriatrics.
2001 Jun; 32(3):265-73. doi:
10.1016/s0167-4943(01)00089-9. [PMID: 11395172] - H Knauf, W Cawello, G Schmidt, E Mutschler. The saluretic effect of the thiazide diuretic bemetizide in relation to the glomerular filtration rate.
European journal of clinical pharmacology.
1994; 46(1):9-13. doi:
10.1007/bf00195908. [PMID: 8005195] - E Fritschka, G Schmidt. [Long-term efficacy and side effect profile of a low-dose bemetizid-triamterene combination in patients with essential hypertension].
Medizinische Klinik (Munich, Germany : 1983).
1989 Nov; 84(11):526-33. doi:
NULL. [PMID: 2512474] - R Düsing, V Nicolas, B Glatte, K Glänzer, J Kipnowski, H J Kramer. Interaction of bemetizide and indomethacin in the kidney.
British journal of clinical pharmacology.
1983 Oct; 16(4):377-83. doi:
10.1111/j.1365-2125.1983.tb02181.x. [PMID: 6578835] - C Piper, W Cawello, R Bonn, E Weber. [Pharmacodynamics and pharmacokinetics of bemetizid in comparison with hydrochlorothiazide. A controlled human pharmacologic study of acute effects].
Arzneimittel-Forschung.
1983; 33(7):988-96. doi:
NULL. [PMID: 6684935] - R R Brodie, L F Chasseaud, A Darragh, T Taylor, L M Walmsley. Bioavailability of bemetizide and triamterene from a combination formulation.
Biopharmaceutics & drug disposition.
1982 Oct; 3(4):361-70. doi:
10.1002/bdd.2510030409. [PMID: 7159690] - H J Liewald, A Schrey, R Grund. [Low diuretic dosage in a beta blocker-diuretic combination].
Medizinische Klinik.
1980 Aug; 75(18):654-7. doi:
NULL. [PMID: 6106884] - R R Brodie, L F Chasseaud, T Taylor. Determination of the thiazide diuretic bemetizide in the plasma and urine of humans by high-performance liquid chromatography.
Journal of chromatography.
1978 Jul; 146(1):152-6. doi:
10.1016/s0378-4347(00)81301-8. [PMID: 670351]