Dextromoramide (BioDeep_00000408882)

   


代谢物信息卡片


(3S)-3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-ylbutan-1-one

化学式: C25H32N2O2 (392.24636519999996)
中文名称: 右吗拉胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(c(c4)cccc4)(c(c3)cccc3)(C(=O)N(C2)CCC2)C([H])(C)CN(C1)CCOC1
InChI: InChI=1S/C25H32N2O2/c1-21(20-26-16-18-29-19-17-26)25(22-10-4-2-5-11-22,23-12-6-3-7-13-23)24(28)27-14-8-9-15-27/h2-7,10-13,21H,8-9,14-20H2,1H3/t21-/m1/s1

描述信息

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics
N - Nervous system > N02 - Analgesics > N02A - Opioids > N02AC - Diphenylpropylamine derivatives
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist
D002491 - Central Nervous System Agents > D000700 - Analgesics

同义名列表

2 个代谢物同义名

(3S)-3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-ylbutan-1-one; Dextromoramide



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • V Cirimele, S Etienne, M Villain, B Ludes, P Kintz. Evaluation of the One-Step ELISA kit for the detection of buprenorphine in urine, blood, and hair specimens. Forensic science international. 2004 Jul; 143(2-3):153-6. doi: 10.1016/j.forsciint.2004.02.035. [PMID: 15240036]
  • V Cirimele, P Kintz, S Lohner, B Ludes. Enzyme immunoassay validation for the detection of buprenorphine in urine. Journal of analytical toxicology. 2003 Mar; 27(2):103-5. doi: 10.1093/jat/27.2.103. [PMID: 12670004]
  • J W de Vos, J G Ufkes, W van den Brink, G H van Brussel, F A de Wolff. Craving patterns in methadone maintenance treatment with dextromoramide as adjuvant. Addictive behaviors. 1999 Sep; 24(5):707-13. doi: 10.1016/s0306-4603(98)00081-1. [PMID: 10574310]
  • J G Ufkes, J W de Vos, G H van Brussel. Determination and pharmacokinetics of dextromoramide in methadone maintenance therapy. Pharmacy world & science : PWS. 1998 Apr; 20(2):83-7. doi: 10.1023/a:1008699623190. [PMID: 9584342]
  • P P Rop, F Grimaldi, M Bresson, J Spinazzola, J Quicke, A Viala. Determination of dextromoramide in plasma and whole blood using high-performance liquid chromatography with ultraviolet absorbance detection. Journal of chromatography. 1992 Jan; 573(1):87-92. doi: 10.1016/0378-4347(92)80478-9. [PMID: 1564110]
  • P Kintz, P Mangin, A A Lugnier, A J Chaumont. Determination of dextromoramide by capillary gas chromatography and electron impact mass spectrometry. Journal of analytical toxicology. 1990 Jul; 14(4):252-3. doi: 10.1093/jat/14.4.252. [PMID: 2395349]
  • E Brewer. A dextromoramide-related fatality. Journal of forensic sciences. 1990 Mar; 35(2):483-9. doi: NULL. [PMID: 2329340]
  • P J Reilly, C J Suann, A M Duffield. Gas chromatographic mass-specific investigation of dextromoramide (Palfium) metabolism in the horse. Journal of chromatography. 1990 Jan; 498(1):35-40. doi: 10.1016/s0021-9673(01)84233-3. [PMID: 2295688]
  • P Kintz, A Tracqui, B Ludes, P Mangin, A A Lugnier, A J Chaumont. Identification and determination of dextromoramide, a nonopiate narcotic. Acta medicinae legalis et socialis. 1989; 39(1):393-5. doi: . [PMID: 2520722]
  • G Misztal, L Przyborowski, T Jednacz. [Chromatographic identification and analysis of dextromoramide in the plasma by the method of high performance liquid chromatography]. Acta poloniae pharmaceutica. 1989; 46(2):155-9. doi: NULL. [PMID: 2631568]
  • I Pagani, N Barzaghi, F Crema, E Perucca, D Ego, V Rovei. Pharmacokinetics of dextromoramide in surgical patients. Fundamental & clinical pharmacology. 1989; 3(1):27-35. doi: 10.1111/j.1472-8206.1989.tb00027.x. [PMID: 2714730]
  • J P Lançon, A Pechinot, P D Athis, M Pechinot, P Pointaire, J F Obadia, B Caillard. [Pharmacokinetics of dextromoramide in the surgical patient]. Annales francaises d'anesthesie et de reanimation. 1989; 8(5):488-92. doi: 10.1016/s0750-7658(89)80015-2. [PMID: 2576345]
  • P Kintz, A Tracqui, P Mangin, A Lugnier, A Chaumont. Toxicological findings after fatal dextromoramide injection. Journal of toxicology. Clinical toxicology. 1989; 27(6):385-8. doi: 10.3109/15563658909000359. [PMID: 2628587]
  • P Kintz, P Mangin, A A Lugnier, A J Chaumont. Gas chromatographic assay for dextromoramide in human plasma. Journal of chromatography. 1988 Nov; 432(?):329-33. doi: 10.1016/s0378-4347(00)80661-1. [PMID: 3220902]
  • B Caddy, R Idowu. Oxidative determination of dextromoramide (Palfium) in body fluids. The Analyst. 1979 Apr; 104(1237):328-33. doi: 10.1039/an9790400328. [PMID: 443555]
  • L J Dusci, L P Hackett. The detection of some basic drugs and their major metabolites using gas-liquid chromatography. Clinical toxicology. 1979; 14(5):587-93. doi: 10.3109/15563657908992469. [PMID: 498728]
  • R Chacornac, M Charlot, N Duret, R Tempelhoff, R Deleuze, C Lapras, R Deruty. [General anesthesiologic conditions in the surgical treatment of intracranial aneurysms under induced hypotension with sodium nitroprusside]. Neuro-Chirurgie. 1978; 24(3):155-63. doi: NULL. [PMID: 755193]
  • T Tammisto. Effects of neuroleptanesthesia on catecholamines. International anesthesiology clinics. 1973; 11(3):185-95. doi: 10.1097/00004311-197301130-00014. [PMID: 4150387]
  • A Jäättelä, P Nikki, S Takki, T Tammisto. Effect of dextromoramide, fentanyl and morphine on the plasma catecholamine levels. Annals of clinical research. 1971 Apr; 3(2):107-11. doi: NULL. [PMID: 5555829]
  • D Mönkemeier, U Steffen. [The management of pain with imipramine in cancer]. Medizinische Klinik. 1970 Jan; 65(5):213-5. doi: NULL. [PMID: 5413360]
  • L M Gunne, C G Sandberg. [Addiction treatment center at Ulleråker. 1. Drug addiction control]. Lakartidningen. 1969 Jan; 66(5):432-6. doi: NULL. [PMID: 5782063]
  • L Buchel, L Liblau, M Murawsky, M Prioux-Guyonneau. [Influence of pyschotropic substances on variations of total plasma free fatty acids in constrained rats]. Archives des sciences physiologiques. 1969; 23(3):407-14. doi: NULL. [PMID: 5808000]