Ethenzamide (BioDeep_00000408877)
代谢物信息卡片
化学式: C9H11NO2 (165.0789746)
中文名称: 2-乙氧基苯甲酰胺, 乙苯甲酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOc(c1)c(ccc1)C(N)=O
InChI: InChI=1S/C9H11NO2/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6H,2H2,1H3,(H2,10,11)
描述信息
N - Nervous system > N02 - Analgesics > N02B - Other analgesics and antipyretics > N02BA - Salicylic acid and derivatives
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
同义名列表
3 个代谢物同义名
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Ilho Kim, Naoyuki Yamashita, Hiroaki Tanaka. Photodegradation of pharmaceuticals and personal care products during UV and UV/H2O2 treatments.
Chemosphere.
2009 Oct; 77(4):518-25. doi:
10.1016/j.chemosphere.2009.07.041. [PMID: 19712957] - Patrick Poulin, Frank-Peter Theil. Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition.
Journal of pharmaceutical sciences.
2002 May; 91(5):1358-70. doi:
10.1002/jps.10128. [PMID: 11977112] - E Tanaka, T Nakamura, A Nagashima, K Yamazaki, N Ohashi, H Tsuchihashi, S Misawa. Determination of plasma bromvalerylurea and its main metabolite by a simple high-performance liquid chromatographic method and quantitation of bromide by energy dispersive X-ray spectrometry in carbon tetrachloride-intoxicated rats.
Journal of chromatography. B, Biomedical sciences and applications.
2001 Aug; 759(2):361-6. doi:
10.1016/s0378-4347(01)00244-4. [PMID: 11499491] - Y Miyamoto, A Ryu, S Sugawara, M Miyajima, S Ogawa, M Matsui, K Takayama, T Nagai. Simultaneous optimization of wet granulation process involving factor of drug content dependency on granule size.
Drug development and industrial pharmacy.
1998 Nov; 24(11):1055-65. doi:
10.3109/03639049809089949. [PMID: 9876560] - Y Miyamoto, A Ryu, S Sugawara, M Miyajima, M Matsui, K Takayama, T Nagai. Optimization of the granulation process for designing tablets.
Chemical & pharmaceutical bulletin.
1998 Sep; 46(9):1432-7. doi:
10.1248/cpb.46.1432. [PMID: 9775438] - P H Tan, A K Chou, J S Perng. Accidental shock during epidural anesthesia in a patient with NSAID-induced hyporeninemic hypoaldosteronism.
Journal of clinical anesthesia.
1997 Aug; 9(5):424-7. doi:
10.1016/s0952-8180(97)00072-x. [PMID: 9257212] - T Takayasu, J Nishigami, T Ohshima, Z Lin, T Kondo, T Nakaya, T Sawaguchi, T Nagano. [A fatal case due to intoxication with seven drugs detected by GC-MS and TDx methods].
Nihon hoigaku zasshi = The Japanese journal of legal medicine.
1993 Feb; 47(1):63-71. doi:
. [PMID: 8315862] - X D Liu, J Chen. Trapezoidal area method for simulating physiological pharmacokinetics of drugs in animals.
European journal of drug metabolism and pharmacokinetics.
1991 Oct; 16(4):281-5. doi:
10.1007/bf03189973. [PMID: 1823872] - S Asada, H Fujii, H Nakae. [Application of multi-lines fitting technic for ethenzamide elimination with capacity-limited process in the rabbit plasma].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
1989 Jul; 109(7):499-504. doi:
10.1248/yakushi1947.109.7_499. [PMID: 2585261] - S K Podder, T Nakamura, M Nakashima, H Sasaki, J Nakamura, J Shibasaki. Comparison of salicylamide and acetaminophen and their prodrug disposition in dogs.
Journal of pharmacobio-dynamics.
1988 May; 11(5):324-9. doi:
10.1248/bpb1978.11.324. [PMID: 3171875] - J H Lin, Y Sugiyama, M Hanano, S Awazu. Effect of product inhibition on elimination kinetics of ethoxybenzamide in rabbits. Analysis by physiological pharmacokinetic model.
Drug metabolism and disposition: the biological fate of chemicals.
1984 Mar; 12(2):253-6. doi:
NULL. [PMID: 6144493] - K Kigasawa, M Hiiragi, T Hayashi, K Maruyama. [Biopharmaceutical studies of drugs (6). Effect of 2-bromo-isovalerylurea on serum concentrations of O-ethoxybenzamide and N-(beta-hydroxybutyryl)-p-phenetidine in rabbits].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
1983 May; 103(5):559-65. doi:
. [PMID: 6644546] - J H Lin, Y Sugiyama, S Awazu, M Hanano. Physiological pharmacokinetics of ethoxybenzamide based on biochemical data obtained in vitro as well as on physiological data.
Journal of pharmacokinetics and biopharmaceutics.
1982 Dec; 10(6):649-61. doi:
10.1007/bf01062546. [PMID: 7182460] - K Kigasawa, M Hiiragi, T Hayashi. [Biopharmaceutical studies of drugs. III. Serum concentration level of o-ethoxybenzamide and N-(beta-hydroxybutyryl)-p-phenetidine after simultaneous administration to rabbit (author's transl)].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
1981 Jun; 101(6):556-66. doi:
10.1248/yakushi1947.101.6_556. [PMID: 7310638]
