3,4-DICHLOROANILINE (BioDeep_00000408591)

Main id: BioDeep_00000003029

 


代谢物信息卡片


3,4-DICHLOROANILINE

化学式: C6H5Cl2N (160.979903)
中文名称: 3,4-二氯苯胺, 3,4-二氯苯胺-ul-14C
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1N)Cl)Cl
InChI: InChI=1S/C6H5Cl2N/c7-5-2-1-4(9)3-6(5)8/h1-3H,9H2

描述信息

CONFIDENCE standard compound; INTERNAL_ID 4004

同义名列表

1 个代谢物同义名

3,4-DICHLOROANILINE



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mingyu Sang, Shuyu Liu, Haohao Yan, Bing Zhang, Siyuan Chen, Bowen Wu, Tian Ma, Hanyi Jiang, Peichao Zhao, Guanjun Sun, Xinyan Gao, Hailian Zang, Yi Cheng, Chunyan Li. Synergistic detoxification efficiency and mechanism of triclocarban degradation by a bacterial consortium in the liver-gut-microbiota axis of zebrafish (Danio rerio). Journal of hazardous materials. 2024 May; 470(?):134178. doi: 10.1016/j.jhazmat.2024.134178. [PMID: 38608581]
  • Md Nurul Huda Bhuiyan, Habyeong Kang, Jiwon Choi, Soyoung Lim, Younglim Kho, Kyungho Choi. Effects of 3,4-dichloroaniline (3,4-DCA) and 4,4'-methylenedianiline (4,4'-MDA) on sex hormone regulation and reproduction of adult zebrafish (Danio rerio). Chemosphere. 2021 Apr; 269(?):128768. doi: 10.1016/j.chemosphere.2020.128768. [PMID: 33153842]
  • Pieter Albers, Bram Weytjens, René De Mot, Kathleen Marchal, Dirk Springael. Molecular processes underlying synergistic linuron mineralization in a triple-species bacterial consortium biofilm revealed by differential transcriptomics. MicrobiologyOpen. 2018 04; 7(2):e00559. doi: 10.1002/mbo3.559. [PMID: 29314727]
  • Zhongli Chen, Burkhard Schmidt, Andreas Schäffer. Uptake and decomposition of the herbicide propanil in the plant Bidens pilosa L. dominating in the Yangtze Three Gorges Reservoir (TGR), China. Environmental science and pollution research international. 2017 Apr; 24(12):11141-11153. doi: 10.1007/s11356-016-6068-8. [PMID: 26846318]
  • Jingwei Feng, Runlong Liu, Pei Chen, Shoujun Yuan, Dayong Zhao, Jibiao Zhang, Zheng Zheng. Degradation of aqueous 3,4-dichloroaniline by a novel dielectric barrier discharge plasma reactor. Environmental science and pollution research international. 2015 Mar; 22(6):4447-59. doi: 10.1007/s11356-014-3690-1. [PMID: 25315933]
  • Mitscheli S Da Rocha, Lora L Arnold, Puttappa R Dodmane, Karen L Pennington, Fang Qiu, João Lauro V De Camargo, Samuel M Cohen. Diuron metabolites and urothelial cytotoxicity: in vivo, in vitro and molecular approaches. Toxicology. 2013 Dec; 314(2-3):238-46. doi: 10.1016/j.tox.2013.10.005. [PMID: 24172598]
  • Beatriz Jurado-Sánchez, Evaristo Ballesteros, Mercedes Gallego. Occurrence of aromatic amines and N-nitrosamines in the different steps of a drinking water treatment plant. Water research. 2012 Sep; 46(14):4543-55. doi: 10.1016/j.watres.2012.05.039. [PMID: 22703862]
  • Selly Jemutai-Kimosop, Francis Orata, Zachary Getenga. The influence of filter mud compost and Tithonia diversifolia leaves on the dissipation of diuron in soils within the Nzoia River Drainage Basin, Kenya. Bulletin of environmental contamination and toxicology. 2012 Aug; 89(2):328-33. doi: 10.1007/s00128-012-0685-9. [PMID: 22617949]
  • Federico M Rubino, Stefan Mandic-Rajcevic, Eugenio Ariano, Athanasios Alegakis, Monica Bogni, Gabri Brambilla, Gioia De Paschale, Anna Firmi, Claudio Minoia, Giuseppina Micoli, Simona Savi, Cristina Sottani, Chiara Somaruga, Roberta Turci, Francesca Vellere, Aristidis Tsatsakis, Claudio Colosio. Farmers' exposure to herbicides in North Italy: assessment under real-life conditions in small-size rice and corn farms. Toxicology letters. 2012 Apr; 210(2):189-97. doi: 10.1016/j.toxlet.2012.01.017. [PMID: 22306369]
  • Dehua Guo, Xionghai Yi, Li Qu. [Determination of linuron and its metabolite 3,4-dichloroaniline residues in meat and meat products using liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2011 Oct; 29(10):967-73. doi: . [PMID: 22268352]
  • Xie-Feng Yao, Fazlurrahman Khan, Rinku Pandey, Janmejay Pandey, Roslyn G Mourant, Rakesh K Jain, Jian-Hua Guo, Robyn J Russell, John G Oakeshott, Gunjan Pandey. Degradation of dichloroaniline isomers by a newly isolated strain, Bacillus megaterium IMT21. Microbiology (Reading, England). 2011 Mar; 157(Pt 3):721-726. doi: 10.1099/mic.0.045393-0. [PMID: 21163842]
  • . Toxicology and carcinogenesis studies of 3,3',4,4'-tetrachloroazobenzene (TCAB) (CAS No. 14047-09-7) in Harlan Sprague-Dawley rats and B6C3F1 mice (gavage studies). National Toxicology Program technical report series. 2010 Nov; ?(558):1-206. doi: . [PMID: 21383777]
  • Jiyan Liu, Dingfei Hu, Guibin Jiang, Jerald L Schnoor. In vivo biotransformation of 3,3',4,4'-tetrachlorobiphenyl by whole plants-poplars and switchgrass. Environmental science & technology. 2009 Oct; 43(19):7503-9. doi: 10.1021/es901244h. [PMID: 19848168]
  • Birgitta Kütting, Thomas Göen, Ursula Schwegler, Hermann Fromme, Wolfgang Uter, Jürgen Angerer, Hans Drexler. Monoarylamines in the general population--a cross-sectional population-based study including 1004 Bavarian subjects. International journal of hygiene and environmental health. 2009 May; 212(3):298-309. doi: 10.1016/j.ijheh.2008.07.004. [PMID: 18789761]
  • Darren M Roberts, Renate Heilmair, Nick A Buckley, Andrew H Dawson, Mohamed Fahim, Michael Eddleston, Peter Eyer. Clinical outcomes and kinetics of propanil following acute self-poisoning: a prospective case series. BMC clinical pharmacology. 2009 Feb; 9(?):3. doi: 10.1186/1472-6904-9-3. [PMID: 19220887]
  • Peter R Stork, Frederick R Bennett, Michael J Bell. The environmental fate of diuron under a conventional production regime in a sugarcane farm during the plant cane phase. Pest management science. 2008 Sep; 64(9):954-63. doi: 10.1002/ps.1593. [PMID: 18470961]
  • Yang Zhao, Tszfung F Chow, Rachel S Puckrin, Simon E Alfred, Albert K Korir, Cynthia K Larive, Sean R Cutler. Chemical genetic interrogation of natural variation uncovers a molecule that is glycoactivated. Nature chemical biology. 2007 Nov; 3(11):716-21. doi: 10.1038/nchembio.2007.32. [PMID: 17891152]
  • Melissa Brazier-Hicks, Lesley A Edwards, Robert Edwards. Selection of plants for roles in phytoremediation: the importance of glucosylation. Plant biotechnology journal. 2007 Sep; 5(5):627-35. doi: 10.1111/j.1467-7652.2007.00266.x. [PMID: 17573805]
  • Emanuela Corsini, Ilaria Codecà, Simona Mangiaratti, Sarah Birindelli, Claudio Minoia, Roberta Turci, Barbara Viviani, Alessandra Facchi, Nora Vitelli, Laura Lucchi, Corrado L Galli, Marina Marinovich, Claudio Colosio. Immunomodulatory effects of the herbicide propanil on cytokine production in humans: In vivo and in vitro exposure. Toxicology and applied pharmacology. 2007 Jul; 222(2):202-10. doi: 10.1016/j.taap.2007.04.017. [PMID: 17585980]
  • N Vitelli, A Chiodini, C Colosio, G De Paschale, C Somaruga, R Turci, C Minoia, G Brambilla, A Colombi. [Occupational and environmental exposure to anilide and dicarboximide pesticides]. Giornale italiano di medicina del lavoro ed ergonomia. 2007 Jul; 29(3 Suppl):276-7. doi: . [PMID: 18409684]
  • Young-Mog Kim, Kunbawui Park, Won-Chan Kim, Jae-Ho Shin, Jang-Eok Kim, Heui-Dong Park, In-Koo Rhee. Cloning and characterization of a catechol-degrading gene cluster from 3,4-dichloroaniline degrading bacterium Pseudomonas sp. KB35B. Journal of agricultural and food chemistry. 2007 Jun; 55(12):4722-7. doi: 10.1021/jf070116f. [PMID: 17497880]
  • Kiriakoula Mitsou, Artemissia Koulianou, Dimitra Lambropoulou, Periklis Pappas, Triantafyllos Albanis, Marilena Lekka. Growth rate effects, responses of antioxidant enzymes and metabolic fate of the herbicide Propanil in the aquatic plant Lemna minor. Chemosphere. 2006 Jan; 62(2):275-84. doi: 10.1016/j.chemosphere.2005.05.026. [PMID: 16005045]
  • Roberta Turci, Angelo Barisano, Claudio Balducci, Claudio Colosio, Claudio Minoia. Determination of dichloroanilines in human urine by gas chromatography/mass spectrometry: validation protocol and establishment of Reference Values in a population group living in central Italy. Rapid communications in mass spectrometry : RCM. 2006; 20(17):2621-5. doi: 10.1002/rcm.2658. [PMID: 16897789]
  • Melissa Brazier-Hicks, Robert Edwards. Functional importance of the family 1 glucosyltransferase UGT72B1 in the metabolism of xenobiotics in Arabidopsis thaliana. The Plant journal : for cell and molecular biology. 2005 May; 42(4):556-66. doi: 10.1111/j.1365-313x.2005.02398.x. [PMID: 15860014]
  • Jin-feng Peng, Jing-fu Liu, Gui-bin Jiang, Chao Tai, Min-jia Huang. Ionic liquid for high temperature headspace liquid-phase microextraction of chlorinated anilines in environmental water samples. Journal of chromatography. A. 2005 Apr; 1072(1):3-6. doi: 10.1016/j.chroma.2004.11.060. [PMID: 15881452]
  • Wei-min Li, Da-qiang Yin, Yan Zhou, Shuang-qing Hu, Lian-sheng Wang. 3,4-dichloroaniline-induced oxidative stress in liver of crucian carp (Carassius auratus). Ecotoxicology and environmental safety. 2003 Oct; 56(2):251-5. doi: 10.1016/s0147-6513(02)00117-3. [PMID: 12927556]
  • Si-Houy Lao, Caroline Loutre, Melissa Brazier, Julian O D Coleman, David J Cole, Robert Edwards, Frederica L Theodoulou. 3,4-Dichloroaniline is detoxified and exported via different pathways in Arabidopsis and soybean. Phytochemistry. 2003 Jul; 63(6):653-61. doi: 10.1016/s0031-9422(03)00289-9. [PMID: 12842137]
  • Caroline Loutre, David P Dixon, Melissa Brazier, Malcolm Slater, David J Cole, Robert Edwards. Isolation of a glucosyltransferase from Arabidopsis thaliana active in the metabolism of the persistent pollutant 3,4-dichloroaniline. The Plant journal : for cell and molecular biology. 2003 May; 34(4):485-93. doi: 10.1046/j.1365-313x.2003.01742.x. [PMID: 12753587]
  • Tobias Weiss, Jürgen Angerer. Simultaneous determination of various aromatic amines and metabolites of aromatic nitro compounds in urine for low level exposure using gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Oct; 778(1-2):179-92. doi: 10.1016/s0378-4347(01)00542-4. [PMID: 12376125]
  • Monica A Valentovic, John G Ball, H Sun, Gary O Rankin. Characterization of 2-amino-4,5-dichlorophenol (2A45CP) in vitro toxicity in renal cortical slices from male Fischer 344 rats. Toxicology. 2002 Mar; 172(2):113-23. doi: 10.1016/s0300-483x(01)00597-2. [PMID: 11882351]
  • Yasushi Hori, Mariko Nakajima, Manami Fujisawa, Kenji Shimada, Tetsuya Hirota, Toshiharu Yoshioka. [Simultaneous determination of propanil, carbaryl and 3,4-dichloroaniline in human serum by HPLC with UV detector following solid phase extraction]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2002 Mar; 122(3):247-51. doi: 10.1248/yakushi.122.247. [PMID: 11905049]
  • Marbouh L El, C Arellano, C Philibert, P Evrard, J Poey, G Houin. Development and evaluation of an HPLC urinalysis screening test for occupational exposure to 3,4- and 3,5-dichloroanilines. International journal of clinical pharmacology and therapeutics. 2002 Jan; 40(1):41-6. doi: 10.5414/cpp40041. [PMID: 11837382]
  • M Valentovic, J G Ball, S Stoll, G O Rankin. 3,4-Dichlorophenylhydroxylamine cytotoxicity in renal cortical slices from Fischer 344 rats. Toxicology. 2001 May; 162(3):149-56. doi: 10.1016/s0300-483x(01)00356-0. [PMID: 11369111]
  • K Wittke, H Hajimiragha, L Dunemann, J Begerow. Determination of dichloroanilines in human urine by GC-MS, GC-MS-MS, and GC-ECD as markers of low-level pesticide exposure. Journal of chromatography. B, Biomedical sciences and applications. 2001 May; 755(1-2):215-28. doi: 10.1016/s0378-4347(01)00078-0. [PMID: 11393707]
  • L Guilhermino, A M Soares, A P Carvalho, M C Lopes. Acute effects of 3,4-dichloroaniline on blood of male Wistar rats. Chemosphere. 1998 Aug; 37(4):619-32. doi: 10.1016/s0045-6535(98)00087-3. [PMID: 9693839]
  • M A Valentovic, T Yahia, J G Ball, S K Hong, P I Brown, G O Rankin. 3,4-Dicholoroaniline acute toxicity in male Fischer 344 rats. Toxicology. 1997 Dec; 124(2):125-34. doi: 10.1016/s0300-483x(97)00143-1. [PMID: 9458002]
  • H H Lo, P I Brown, G O Rankin. Trichloroaniline effects on renal function in vivo and in vitro. Toxicology letters. 1991 Aug; 57(3):319-28. doi: 10.1016/0378-4274(91)90206-l. [PMID: 1882391]
  • D J Baird, I Barber, A M Soares, P Calow. An early life-stage test with Daphnia magna Straus: an alternative to the 21-day chronic test?. Ecotoxicology and environmental safety. 1991 Aug; 22(1):1-7. doi: 10.1016/0147-6513(91)90040-v. [PMID: 1914991]
  • H Sandermann, R Schmitt, H Eckey, T Bauknecht. Plant biochemistry of xenobiotics: isolation and properties of soybean O- and N-glucosyl and O- and N-malonyltransferases for chlorinated phenols and anilines. Archives of biochemistry and biophysics. 1991 Jun; 287(2):341-50. doi: 10.1016/0003-9861(91)90488-5. [PMID: 1832837]
  • B L Worobey, J B Shields. Preliminary studies on the bioavailability and disposition of bioincurred carrot residues of [14C] linuron and [14C]3,4-dichloroaniline in rats. Food additives and contaminants. 1991 Mar; 8(2):193-200. doi: 10.1080/02652039109373969. [PMID: 1868930]
  • L Maltby, C Naylor, P Calow. Effect of stress on a freshwater benthic detritivore: scope for growth in Gammarus pulex. Ecotoxicology and environmental safety. 1990 Jun; 19(3):285-91. doi: 10.1016/0147-6513(90)90030-9. [PMID: 2364911]
  • . . . . doi: . [PMID: 18487633]