Chaetoglobosin C (BioDeep_00000408544)

   


代谢物信息卡片


(1R,7Z,9S,11Z,13R,14S,16R,17S,18R,19S)-19-(1H-indol-3-ylmethyl)-7,9,16,17-tetramethyl-15-oxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-7,11-diene-2,5,6,21-tetrone

化学式: C32H36N2O5 (528.2624086)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC=CC2C3C(O3)(C(C4C2(C(=O)CCC(=O)C(=O)C(=C1)C)C(=O)NC4CC5=CNC6=CC=CC=C65)C)C
InChI: InChI=1S/C32H36N2O5/c1-17-8-7-10-22-29-31(4,39-29)19(3)27-24(15-20-16-33-23-11-6-5-9-21(20)23)34-30(38)32(22,27)26(36)13-12-25(35)28(37)18(2)14-17/h5-7,9-11,14,16-17,19,22,24,27,29,33H,8,12-13,15H2,1-4H3,(H,34,38)/b10-7+,18-14+/t17-,19-,22-,24-,27-,29?,31+,32+/m0/s1

描述信息

A cytochalasan alkaloid found in Chaetomium globosum and Chaetomium subaffine.
CONFIDENCE isolated standard

同义名列表

2 个代谢物同义名

Chaetoglobosin C; (1R,7Z,9S,11Z,13R,14S,16R,17S,18R,19S)-19-(1H-indol-3-ylmethyl)-7,9,16,17-tetramethyl-15-oxa-20-azatetracyclo[11.8.0.01,18.014,16]henicosa-7,11-diene-2,5,6,21-tetrone



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Fangfang Duan, Chunlun Qin, Zihuan Sang, Xiaoyi Wei, Hanli Ruan. Lignans and [11]-chaetoglobosins from Pseudeurotium bakeri and their immunosuppressive activity. Organic & biomolecular chemistry. 2024 03; 22(11):2271-2278. doi: 10.1039/d3ob02109b. [PMID: 38391281]
  • Fangfang Duan, Xiaogang Peng, Lin Liu, Xianggao Meng, An Jin, Hanli Ruan. Chaepseubakerins A-J, ten undescribed cytotoxic [11]-chaetoglobosins from an endophytic fungus Pseudeurotium bakeri. Phytochemistry. 2024 Feb; 218(?):113939. doi: 10.1016/j.phytochem.2023.113939. [PMID: 38052264]
  • Lingan Rajendran, Dhakshinamoorthy Durgadevi, Rangasamy Kavitha, Sivashanmugam Divya, Kuppandy Ganeshan, Pandia Maharajan Vetrivelkalai, Gandhi Karthikeyan, Thiruvengadam Raguchander. Characterization of chaetoglobosin producing Chaetomium globosum for the management of Fusarium-Meloidogyne wilt complex in tomato. Journal of applied microbiology. 2023 Feb; 134(2):. doi: 10.1093/jambio/lxac074. [PMID: 36626751]
  • A Linkies, S Jacob, P Zink, M Maschemer, W Maier, E Koch. Characterization of cultural traits and fungicidal activity of strains belonging to the fungal genus Chaetomium. Journal of applied microbiology. 2021 Jul; 131(1):375-391. doi: 10.1111/jam.14946. [PMID: 33249672]
  • Xiao-Wei Luo, Cheng-Hai Gao, Hu-Mu Lu, Jia-Min Wang, Zi-Qi Su, Hua-Ming Tao, Xue-Feng Zhou, Bin Yang, Yong-Hong Liu. HPLC-DAD-Guided Isolation of Diversified Chaetoglobosins from the Coral-Associated Fungus Chaetomium globosum C2F17. Molecules (Basel, Switzerland). 2020 Mar; 25(5):. doi: 10.3390/molecules25051237. [PMID: 32182966]
  • Jacob P Walsh, Justin B Renaud, Shawn Hoogstra, David R McMullin, Ashraf Ibrahim, Cobus M Visagie, Joey B Tanney, Ken K-C Yeung, Mark W Sumarah. Diagnostic fragmentation filtering for the discovery of new chaetoglobosins and cytochalasins. Rapid communications in mass spectrometry : RCM. 2019 Jan; 33(1):133-139. doi: 10.1002/rcm.8306. [PMID: 30325552]
  • Wei Yan, Ling-Ling Cao, Yang-Yang Zhang, Ran Zhao, Shuang-Shuang Zhao, Babar Khan, Yong-Hao Ye. New Metabolites from Endophytic Fungus Chaetomium globosum CDW7. Molecules (Basel, Switzerland). 2018 Nov; 23(11):. doi: 10.3390/molecules23112873. [PMID: 30400338]
  • Cheng Jiang, Jinzhu Song, Junzheng Zhang, Qian Yang. New production process of the antifungal chaetoglobosin A using cornstalks. Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]. 2017 Jul; 48(3):410-418. doi: 10.1016/j.bjm.2016.11.008. [PMID: 28223029]
  • Cheng Jiang, Jinzhu Song, Junzheng Zhang, Qian Yang. Identification and characterization of the major antifungal substance against Fusarium Sporotrichioides from Chaetomium globosum. World journal of microbiology & biotechnology. 2017 Jun; 33(6):108. doi: 10.1007/s11274-017-2274-x. [PMID: 28466302]
  • Shuang-Shuang Zhao, Ying-Ying Zhang, Wei Yan, Ling-Ling Cao, Yu Xiao, Yong-Hao Ye. Chaetomium globosum CDW7, a potential biological control strain and its antifungal metabolites. FEMS microbiology letters. 2017 02; 364(3):. doi: 10.1093/femsle/fnw287. [PMID: 28011695]
  • Samad Ashrafi, Soleiman Helaly, Hans-Josef Schroers, Marc Stadler, Katja R Richert-Poeggeler, Abdelfattah A Dababat, Wolfgang Maier. Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi. PloS one. 2017; 12(7):e0180032. doi: 10.1371/journal.pone.0180032. [PMID: 28700638]
  • Tao Jiang, Menghua Wang, Li Li, Jinguang Si, Bo Song, Cao Zhou, Meng Yu, Xuewei Wang, Yonggang Zhang, Gang Ding, Zhongmei Zou. Overexpression of the Global Regulator LaeA in Chaetomium globosum Leads to the Biosynthesis of Chaetoglobosin Z. Journal of natural products. 2016 10; 79(10):2487-2494. doi: 10.1021/acs.jnatprod.6b00333. [PMID: 27759375]
  • Kristina D Rogers, Joseph C Cannistra, James B Gloer, Donald T Wicklow. Diplodiatoxin, chaetoglobosins, and diplonine associated with a field outbreak of Stenocarpella ear rot in Illinois. Mycotoxin research. 2014 May; 30(2):61-70. doi: 10.1007/s12550-014-0188-0. [PMID: 24504633]
  • Qi-Chang Zheng, Ming-Zhu Kong, Qin Zhao, Guo-Dong Chen, Hai-Yan Tian, Xiao-Xia Li, Liang-Dong Guo, Jia Li, Yi-Zhi Zheng, Hao Gao. Chaetoglobosin Y, a new cytochalasan from Chaetomium globosum. Fitoterapia. 2014 Mar; 93(?):126-31. doi: 10.1016/j.fitote.2013.12.022. [PMID: 24418656]
  • Yang Hu, Weipu Zhang, Ping Zhang, Weibin Ruan, Xudong Zhu. Nematicidal activity of chaetoglobosin A poduced by Chaetomium globosum NK102 against Meloidogyne incognita. Journal of agricultural and food chemistry. 2013 Jan; 61(1):41-6. doi: 10.1021/jf304314g. [PMID: 23214998]
  • Yanhong Wang, Lei Xu, Weiming Ren, Dan Zhao, Yanping Zhu, Xiaomin Wu. Bioactive metabolites from Chaetomium globosum L18, an endophytic fungus in the medicinal plant Curcuma wenyujin. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2012 Feb; 19(3-4):364-8. doi: 10.1016/j.phymed.2011.10.011. [PMID: 22112725]
  • D F Matesic, M L Blommel, J A Sunman, S J Cutler, H G Cutler. Prevention of organochlorine-induced inhibition of gap junctional communication by chaetoglobosin K in astrocytes. Cell biology and toxicology. 2001; 17(6):395-408. doi: 10.1023/a:1013752717500. [PMID: 11787861]
  • T O Larsen, J C Frisvad, G Ravn, T Skaaning. Mycotoxin production by Penicillium expansum on blackcurrant and cherry juice. Food additives and contaminants. 1998 Aug; 15(6):671-5. doi: 10.1080/02652039809374696. [PMID: 10209577]
  • H G Cutler, F G Crumley, R H Cox, R J Cole, J W Dorner, J P Springer, F M Latterell, J E Thean, A E Rossi. Chaetoglobosin K: a new plant growth inhibitor and toxin from Diplodia macrospora. Journal of agricultural and food chemistry. 1980 Jan; 28(1):139-42. doi: 10.1021/jf60227a011. [PMID: 7358926]