5-Deoxyadenosine (BioDeep_00000408245)

Main id: BioDeep_00000003445

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


5-Deoxyadenosine

化学式: C10H13N5O3 (251.10183480000003)
中文名称: 5-脱氧腺苷
谱图信息: 最多检出来源 Homo sapiens(blood) 0.04%

分子结构信息

SMILES: CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
InChI: InChI=1S/C10H13N5O3/c1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15/h2-4,6-7,10,16-17H,1H3,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1

描述信息

A 5-deoxyribonucleoside compound having adenosine as the nucleobase.
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. 5'-Deoxyadenosine shows anti-orthopoxvirus activity[1].
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. 5'-Deoxyadenosine shows anti-orthopoxvirus activity[1].

同义名列表

2 个代谢物同义名

5-Deoxyadenosine; 5'-Deoxyadenosine



数据库引用编号

34 个数据库交叉引用编号

分类词条

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mehmet Oğuz Erbağcı, Gamze Tuna, Semir Köse, Nazlı Ecem Dal-Bekar, Merve Akış, Melis Kant, Sabahattin Altunyurt, Gül Hüray İşlekel. Association between early oxidative DNA damage and iron status in women with gestational diabetes mellitus. Reproductive toxicology (Elmsford, N.Y.). 2021 08; 103(?):171-180. doi: 10.1016/j.reprotox.2021.05.009. [PMID: 34051274]
  • Johanna Rapp, Pascal Rath, Joachim Kilian, Klaus Brilisauer, Stephanie Grond, Karl Forchhammer. A bioactive molecule made by unusual salvage of radical SAM enzyme byproduct 5-deoxyadenosine blurs the boundary of primary and secondary metabolism. The Journal of biological chemistry. 2021 Jan; 296(?):100621. doi: 10.1016/j.jbc.2021.100621. [PMID: 33811856]
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  • Chun-Hong Li, Nan Yu, Shi-Min Jiang, Xiao-Xia Shangguan, Ling-Jian Wang, Xiao-Ya Chen. Down-regulation of S-adenosyl-L: -homocysteine hydrolase reveals a role of cytokinin in promoting transmethylation reactions. Planta. 2008 Jun; 228(1):125-36. doi: 10.1007/s00425-008-0724-2. [PMID: 18350315]
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  • Wolfgang Herrmann, Rima Obeid. Hyperhomocysteinemia and response of methionine cycle intermediates to vitamin treatment in renal patients. Clinical chemistry and laboratory medicine. 2005; 43(10):1039-47. doi: 10.1515/cclm.2005.182. [PMID: 16197295]
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  • Joseph Hsiao, José Martínez-Costas, Javier Benavente, Vikram N Vakharia. Cloning, expression, and characterization of avian reovirus guanylyltransferase. Virology. 2002 May; 296(2):288-99. doi: 10.1006/viro.2002.1427. [PMID: 12069527]
  • Jean-Benoit Frenette Charron, Ghislain Breton, Jean Danyluk, Ingrid Muzac, Ragai K Ibrahim, Fathey Sarhan. Molecular and biochemical characterization of a cold-regulated phosphoethanolamine N-methyltransferase from wheat. Plant physiology. 2002 May; 129(1):363-73. doi: 10.1104/pp.001776. [PMID: 12011366]
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  • H Zhang, H Ford, J S Roth, J A Kelley. Evaluation of a fluorogenic derivatization method for the reversed-phase HPLC analysis of 2'-beta-fluoro-2',3'-dideoxyadenosine, a new anti-AIDS drug. Journal of pharmaceutical and biomedical analysis. 2001 May; 25(2):285-97. doi: 10.1016/s0731-7085(00)00496-9. [PMID: 11275436]
  • R LoBrutto, V Bandarian, O T Magnusson, X Chen, V L Schramm, G H Reed. 5'-Deoxyadenosine contacts the substrate radical intermediate in the active site of ethanolamine ammonia-lyase: 2H and 13C electron nuclear double resonance studies. Biochemistry. 2001 Jan; 40(1):9-14. doi: 10.1021/bi001865s. [PMID: 11141051]
  • S Ollagnier, E Kervio, J Rétey. The role and source of 5'-deoxyadenosyl radical in a carbon skeleton rearrangement catalyzed by a plant enzyme. FEBS letters. 1998 Oct; 437(3):309-12. doi: 10.1016/s0014-5793(98)01258-7. [PMID: 9824314]
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