Zearalenol (BioDeep_00000407651)
natural product
代谢物信息卡片
Zearalenol
化学式: C18H24O5 (320.1623654)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(natural_products) 50%
分子结构信息
SMILES: CC1CCCC(CCCC=CC2=C(C(=CC(=C2)O)O)C(=O)O1)O
InChI: InChI=1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,14,19-21H,2,4-6,8-9H2,1H3/b7-3+
数据库引用编号
16 个数据库交叉引用编号
- PubChem: 5933650
- CAS: 5916-52-9
- CAS: 36455-72-8];[71030-11-0
- MoNA: VF-NPL-QTOF009982
- MoNA: VF-NPL-QTOF009981
- MoNA: VF-NPL-QTOF009980
- MoNA: VF-NPL-QTOF009979
- MoNA: VF-NPL-QTOF009978
- MoNA: VF-NPL-QTOF009977
- MoNA: NGA00880
- MoNA: NGA00879
- MoNA: NGA00878
- MoNA: NGA00877
- MoNA: CB000300
- MoNA: VF-NPL-LTQ000804
- MoNA: VF-NPL-LTQ000803
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Honglei Qu, Yunduo Zheng, Ruifen Kang, Yulong Feng, Pengshuai Li, Yantao Wang, Jie Cheng, Cheng Ji, Wenqiong Chai, Qiugang Ma. Toxicokinetics of Zearalenone following Oral Administration in Female Dezhou Donkeys.
Toxins.
2024 Jan; 16(1):. doi:
10.3390/toxins16010051. [PMID: 38251267] - Jiao Tian, Jiaoyang Luo, Jiaan Qin, Yudan Wang, Xinqi Sun, Jing Zhang, Tongwei Ke, Mengyue Guo, Haonan Ruan, Fang An, Meihua Yang. Preparation of a broad-specificity antibody against zearalenone and its primary analogues and development of immunoassay of Coicis Semen and related products.
Journal of food science.
2023 May; ?(?):. doi:
10.1111/1750-3841.16600. [PMID: 37195191] - Neda Alvarez-Ortega, Karina Caballero-Gallardo, Cristina Juan, Ana Juan-Garcia, Jesus Olivero-Verbel. Cytoprotective, Antiproliferative, and Anti-Oxidant Potential of the Hydroethanolic Extract of Fridericia chica Leaves on Human Cancer Cell Lines Exposed to α- and β-Zearalenol.
Toxins.
2023 Jan; 15(1):. doi:
10.3390/toxins15010036. [PMID: 36668856] - Qian Lu, Ming Sui, Ya-Wen Luo, Jiao-Yang Luo, Mei-Hua Yang. Further insight into the potential toxicity of zearalenone-14-glucoside based on toxicokinetics, tissue distribution, transformation, and excretion in rats.
Ecotoxicology and environmental safety.
2022 Nov; 246(?):114184. doi:
10.1016/j.ecoenv.2022.114184. [PMID: 36244169] - Jennifer Duringer, Rajarshi Mazumder, Valerie Palmer, A Morrie Craig, Peter Spencer. Case-Control Study of Nodding Syndrome in Acholiland: Urinary Multi-Mycotoxin Screening.
Toxins.
2021 04; 13(5):. doi:
10.3390/toxins13050313. [PMID: 33925470] - Ana Juan-García, Giovanni Caprioli, Gianni Sagratini, Jordi Mañes, Cristina Juan. Coffee Silverskin and Spent Coffee Suitable as Neuroprotectors against Cell Death by Beauvericin and α-Zearalenol: Evaluating Strategies of Treatment.
Toxins.
2021 02; 13(2):. doi:
10.3390/toxins13020132. [PMID: 33579040] - Tim Birr, Tolke Jensen, Nils Preußke, Frank D Sönnichsen, Marthe De Boevre, Sarah De Saeger, Mario Hasler, Joseph-Alexander Verreet, Holger Klink. Occurrence of Fusarium Mycotoxins and Their Modified Forms in Forage Maize Cultivars.
Toxins.
2021 02; 13(2):. doi:
10.3390/toxins13020110. [PMID: 33540691] - Christiane Gruber-Dorninger, Johannes Faas, Barbara Doupovec, Markus Aleschko, Christian Stoiber, Andreas Höbartner-Gußl, Karin Schöndorfer, Manuela Killinger, Qendrim Zebeli, Dian Schatzmayr. Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme.
Toxins.
2021 01; 13(2):. doi:
10.3390/toxins13020084. [PMID: 33499402] - Shupeng Yang, Yanshen Li, Marthe De Boevre, Sarah De Saeger, Jinhui Zhou, Yi Li, Huiyan Zhang, Feifei Sun. Toxicokinetics of α-zearalenol and its masked form in rats and the comparative biotransformation in liver microsomes from different livestock and humans.
Journal of hazardous materials.
2020 Jul; 393(?):121403. doi:
10.1016/j.jhazmat.2019.121403. [PMID: 32143155] - Ecem Fatma Karaman, Müjdat Zeybel, Sibel Ozden. Evaluation of the epigenetic alterations and gene expression levels of HepG2 cells exposed to zearalenone and α-zearalenol.
Toxicology letters.
2020 Jun; 326(?):52-60. doi:
10.1016/j.toxlet.2020.02.015. [PMID: 32119988] - Silvia W Gratz, Valerie Currie, Gary Duncan, Diane Jackson. Multimycotoxin Exposure Assessment in UK Children Using Urinary Biomarkers-A Pilot Survey.
Journal of agricultural and food chemistry.
2020 Jan; 68(1):351-357. doi:
10.1021/acs.jafc.9b03964. [PMID: 31826612] - Barbara Gzyl-Malcher, Elżbieta Rudolphi-Skórska, Apolonia Sieprawska, Maria Filek. Manganese protects wheat from the mycotoxin zearalenone and its derivatives.
Scientific reports.
2019 10; 9(1):14214. doi:
10.1038/s41598-019-50664-5. [PMID: 31578385] - José L Hidalgo-Ruiz, Roberto Romero-González, José Luis Martínez Vidal, Antonia Garrido Frenich. A rapid method for the determination of mycotoxins in edible vegetable oils by ultra-high performance liquid chromatography-tandem mass spectrometry.
Food chemistry.
2019 Aug; 288(?):22-28. doi:
10.1016/j.foodchem.2019.03.003. [PMID: 30902285] - Amelie Catteuw, Nathan Broekaert, Siegrid De Baere, Marianne Lauwers, Elke Gasthuys, Bart Huybrechts, Alfons Callebaut, Lada Ivanova, Silvio Uhlig, Marthe De Boevre, Sarah De Saeger, Ronette Gehring, Mathias Devreese, Siska Croubels. Insights into In Vivo Absolute Oral Bioavailability, Biotransformation, and Toxicokinetics of Zearalenone, α-Zearalenol, β-Zearalenol, Zearalenone-14-glucoside, and Zearalenone-14-sulfate in Pigs.
Journal of agricultural and food chemistry.
2019 Mar; 67(12):3448-3458. doi:
10.1021/acs.jafc.8b05838. [PMID: 30807145] - Nurshad Ali, Gisela H Degen. Urinary biomarkers of exposure to the mycoestrogen zearalenone and its modified forms in German adults.
Archives of toxicology.
2018 08; 92(8):2691-2700. doi:
10.1007/s00204-018-2261-5. [PMID: 29980802] - Yue Song, Pinggu Wu, Zhengyan Hu, Lijun Yang, Ying Chen. [Determination of zearalenone and α-zearalenol in vegetable oil and grain products by C_(18)-Al_2O_3 solid phase extraction column purification coupled with ultra-performance liquid chromatography tandem mass spectrometry].
Wei sheng yan jiu = Journal of hygiene research.
2018 Jul; 47(4):615-620. doi:
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Metabolomics : Official journal of the Metabolomic Society.
2018 02; 14(3):33. doi:
10.1007/s11306-018-1330-3. [PMID: 30830360] - M Takagi, S Uno, E Kokushi, F Sato, Mmp Wijayagunawardane, J Fink-Gremmels. Measurement of urinary concentrations of the mycotoxins zearalenone and sterigmatocystin as biomarkers of exposure in mares.
Reproduction in domestic animals = Zuchthygiene.
2018 Feb; 53(1):68-73. doi:
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Molecular nutrition & food research.
2017 04; 61(4):. doi:
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Toxins.
2017 02; 9(2):. doi:
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Environmental science and pollution research international.
2016 Aug; 23(15):15504-14. doi:
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Environmental toxicology and pharmacology.
2015 Nov; 40(3):722-8. doi:
10.1016/j.etap.2015.08.025. [PMID: 26425942] - Urara Nakamura, Hiroya Kadokawa. The nonsteroidal mycoestrogen zearalenone and its five metabolites suppress LH secretion from the bovine anterior pituitary cells via the estradiol receptor GPR30 in vitro.
Theriogenology.
2015 Nov; 84(8):1342-9. doi:
10.1016/j.theriogenology.2015.07.014. [PMID: 26255852] - Constanze Pietsch, Susanne Kersten, Hana Valenta, Sven Dänicke, Carsten Schulz, Patricia Burkhardt-Holm, Ranka Junge. Effects of Dietary Exposure to Zearalenone (ZEN) on Carp (Cyprinus carpio L.).
Toxins.
2015 Aug; 7(9):3465-80. doi:
10.3390/toxins7093465. [PMID: 26343724] - M Denli, J C Blandon, M E Guynot, S Salado, J F Pérez. Efficacy of activated diatomaceous clay in reducing the toxicity of zearalenone in rats and piglets.
Journal of animal science.
2015 Feb; 93(2):637-45. doi:
10.2527/jas.2014-7356. [PMID: 26020748] - Sven Dänicke, Christina Keese, Ulrich Meyer, Alexander Starke, Asako Kinoshita, Jürgen Rehage. Zearalenone (ZEN) metabolism and residue concentrations in physiological specimens of dairy cows exposed long-term to ZEN-contaminated diets differing in concentrate feed proportions.
Archives of animal nutrition.
2014 Dec; 68(6):492-506. doi:
10.1080/1745039x.2014.973236. [PMID: 25348458] - Johannes Gerding, Benedikt Cramer, Hans-Ulrich Humpf. Determination of mycotoxin exposure in Germany using an LC-MS/MS multibiomarker approach.
Molecular nutrition & food research.
2014 Dec; 58(12):2358-68. doi:
10.1002/mnfr.201400406. [PMID: 25243722] - H Belhassen, I Jiménez-Díaz, R Ghali, H Ghorbel, J M Molina-Molina, N Olea, A Hedili. Validation of a UHPLC-MS/MS method for quantification of zearalenone, α-zearalenol, β-zearalenol, α-zearalanol, β-zearalanol and zearalanone in human urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2014 Jul; 962(?):68-74. doi:
10.1016/j.jchromb.2014.05.019. [PMID: 24907545] - Hui Zhang, Qi Sun, Teng Liu, Lu Ma, Panpan Zhen, Ke Wang, Lingqiao Lu, Xin Liu, Xin Zhang, Dandan Song, Xiaoyun Zuo, Huirong Liu, Wen Wang. Alleviation of plasma homocysteine level by phytoestrogen α-zearalanol might be related to the reduction of cystathionine β-synthase nitration.
BioMed research international.
2014; 2014(?):143192. doi:
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PloS one.
2014; 9(12):e113632. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2013 Dec; 62(?):217-25. doi:
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Environment international.
2013 Jul; 57-58(?):50-9. doi:
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Journal of the science of food and agriculture.
2013 May; 93(7):1584-90. doi:
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Animal science journal = Nihon chikusan Gakkaiho.
2013 Jan; 84(1):28-34. doi:
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The Science of the total environment.
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Drug testing and analysis.
2011 Nov; 3(11-12):777-83. doi:
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Analytical and bioanalytical chemistry.
2011 Nov; 401(9):2831-41. doi:
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Toxicology letters.
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Journal of molecular recognition : JMR.
2011 Sep; 24(5):815-23. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
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Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2010 Nov; 27(11):1558-65. doi:
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The Journal of veterinary medical science.
2010 Mar; 72(3):307-12. doi:
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Toxicology.
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Animal reproduction science.
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The Journal of pediatrics.
2008 May; 152(5):690-5, 695.e1. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2007 Nov; 24(3-4):381-7. doi:
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Applied microbiology and biotechnology.
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Applied microbiology and biotechnology.
2005 Apr; 67(1):106-12. doi:
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Polish journal of veterinary sciences.
2005; 8(3):209-18. doi:
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Endocrine.
2004 Nov; 25(2):121-9. doi:
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Endocrine.
2004 Nov; 25(2):117-9. doi:
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Food additives and contaminants.
2004 Jan; 21(1):52-62. doi:
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Food additives and contaminants.
2003 Sep; 20(9):804-12. doi:
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Magnesium research.
2003 Jun; 16(2):106-10. doi:
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Food additives and contaminants.
2002 Dec; 19(12):1130-7. doi:
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Journal of agricultural and food chemistry.
2002 Apr; 50(9):2494-501. doi:
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