eupomatenoid 5 (BioDeep_00000407289)
natural product
代谢物信息卡片
化学式: C19H18O3 (294.1255878)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC=CC1=CC2=C(C=C1)OC(=C2C)C3=CC(=C(C=C3)O)OC
InChI: InChI=1S/C19H18O3/c1-4-5-13-6-9-17-15(10-13)12(2)19(22-17)14-7-8-16(20)18(11-14)21-3/h4-11,20H,1-3H3/b5-4+
数据库引用编号
23 个数据库交叉引用编号
- PubChem: 6443783
- ChEMBL: CHEMBL4565833
- CAS: 41744-28-9
- MoNA: Bruker_HCD_library000746
- MoNA: VF-NPL-QTOF007663
- MoNA: VF-NPL-QTOF007662
- MoNA: VF-NPL-QTOF007661
- MoNA: VF-NPL-LTQ004928
- MoNA: VF-NPL-QEHF019554
- MoNA: VF-NPL-QEHF019553
- MoNA: VF-NPL-QEHF019552
- MoNA: VF-NPL-QEHF019551
- MoNA: VF-NPL-QEHF019550
- MoNA: VF-NPL-QEHF019549
- MoNA: VF-NPL-QEHF019548
- MoNA: VF-NPL-QEHF019547
- MoNA: VF-NPL-QEHF019546
- MoNA: VF-NPL-QEHF019545
- MoNA: VF-NPL-QEHF019544
- MoNA: VF-NPL-QEHF019543
- MoNA: VF-NPL-QEHF019542
- MoNA: VF-NPL-QEHF019541
- MoNA: VF-NPL-QEHF019540
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Giovanna Barbarini Longato, Giovanna Francisco Fiorito, Débora Barbosa Vendramini-Costa, Ilza Maria de Oliveira Sousa, Sirlene Valério Tinti, Ana Lúcia Tasca Gois Ruiz, Sinara Mônica Vitalino de Almeida, Rafael José Ribeiro Padilha, Mary Ann Foglio, João Ernesto de Carvalho. Different cell death responses induced by eupomatenoid-5 in MCF-7 and 786-0 tumor cell lines.
Toxicology in vitro : an international journal published in association with BIBRA.
2015 Aug; 29(5):1026-33. doi:
10.1016/j.tiv.2015.04.002
. [PMID: 25882683] - M A Lopes, K R C Ferracioli, V L D Siqueira, R B de Lima Scodro, D A G Cortez, R Z da Silva, R F Cardoso. In vitro interaction of eupomatenoid-5 from Piper solmsianum C. DC. var. solmsianum and anti-tuberculosis drugs.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
2014 Dec; 18(12):1513-5. doi:
10.5588/ijtld.14.0229
. [PMID: 25517821] - Shan-Zhai Shang, Huan Chen, Cheng-Qin Liang, Zhong-Hua Gao, Xue Du, Rui-Rui Wang, Yi-Ming Shi, Yong-Tang Zheng, Wei-Lie Xiao, Han-Dong Sun. Phenolic constituents from Parakmeria yunnanensis and their anti-HIV-1 activity.
Archives of pharmacal research.
2013 Oct; 36(10):1223-30. doi:
10.1007/s12272-013-0070-1
. [PMID: 23444043] - D Lazarin-Bidóia, V C Desoti, T Ueda-Nakamura, B P Dias Filho, C V Nakamura, S O Silva. Further evidence of the trypanocidal action of eupomatenoid-5: confirmation of involvement of reactive oxygen species and mitochondria owing to a reduction in trypanothione reductase activity.
Free radical biology & medicine.
2013 Jul; 60(?):17-28. doi:
10.1016/j.freeradbiomed.2013.01.008
. [PMID: 23376033] - R B L Scodro, C T A Pires, V S Carrara, C O T Lemos, L Cardozo-Filho, V A Souza, A G Corrêa, V L D Siqueira, M V C Lonardoni, R F Cardoso, D A G Cortez. Anti-tuberculosis neolignans from Piper regnellii.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2013 May; 20(7):600-4. doi:
10.1016/j.phymed.2013.01.005
. [PMID: 23474218] - Caroline Ortega Terra Lemos, Terezinha Inez Estivalet Svidzinsk, Lilian Cristiane Baeza, Nathielle Miranda, Celso Vataru Nakamura, Diógenes Aparício Garcia Cortez, Lúcio Cardozo-Filho, Vladimir Ferreira Cabral. Evaluation of antifungal activity of extracts of Piper regnellii obtained by supercritical fluid extraction.
Natural product research.
2013; 27(24):2355-9. doi:
10.1080/14786419.2013.830215
. [PMID: 24007562] - Karin Juliane Pelizzaro-Rocha, Phercyles Veiga-Santos, Danielle Lazarin-Bidóia, Tania Ueda-Nakamura, Benedito Prado Dias Filho, Valdecir Farias Ximenes, Sueli Oliveira Silva, Celso Vataru Nakamura. Trypanocidal action of eupomatenoid-5 is related to mitochondrion dysfunction and oxidative damage in Trypanosoma cruzi.
Microbes and infection.
2011 Nov; 13(12-13):1018-24. doi:
10.1016/j.micinf.2011.05.011
. [PMID: 21683800] - Giovanna Barbarini Longato, Larissa Yokota Rizzo, Ilza Maria de Oliveira Sousa, Sirlene Valério Tinti, Ana Possenti, Glyn Mara Figueira, Ana Lúcia Tasca Gois Ruiz, Mary Ann Foglio, João Ernesto de Carvalho. In vitro and in vivo anticancer activity of extracts, fractions, and eupomatenoid-5 obtained from Piper regnellii leaves.
Planta medica.
2011 Sep; 77(13):1482-8. doi:
10.1055/s-0030-1270889
. [PMID: 21391177] - Michele Cristina Vendrametto, Adriana Oliveira dos Santos, Celso Vataru Nakamura, Benedito Prado Dias Filho, Diógenes Aparício Garcia Cortez, Tânia Ueda-Nakamura. Evaluation of antileishmanial activity of eupomatenoid-5, a compound isolated from leaves of Piper regnellii var. pallescens.
Parasitology international.
2010 Jun; 59(2):154-8. doi:
10.1016/j.parint.2009.12.009
. [PMID: 20064628] - Flaviano João Basilio Marçal, Diógenes Aparício Garcia Cortez, Tânia Ueda-Nakamura, Celso Vataru Nakamura, Benedito Prado Dias Filho. Activity of the extracts and neolignans from Piper regnellii against methicillin-resistant Staphylococcus aureus (MRSA).
Molecules (Basel, Switzerland).
2010 Mar; 15(4):2060-9. doi:
10.3390/molecules15042060
. [PMID: 20428025] - Patrícia Shima Luize, Tânia Ueda-Nakamura, Benedito Prado Dias Filho, Diógenes Aparício Garcia Cortez, José Andrés Morgado-Díaz, Wanderley de Souza, Celso Vataru Nakamura. Ultrastructural alterations induced by the neolignan dihydrobenzofuranic eupomatenoid-5 on epimastigote and amastigote forms of Trypanosoma cruzi.
Parasitology research.
2006 Dec; 100(1):31-7. doi:
10.1007/s00436-006-0241-9
. [PMID: 16783543] - B Freixa, R Vila, E A Ferro, T Adzet, S Cañigueral. Antifungal principles from Piper fulvescens.
Planta medica.
2001 Dec; 67(9):873-5. doi:
10.1055/s-2001-18838
. [PMID: 11745030]