5,7-Dihydroxyisoflavone (BioDeep_00000407044)
natural product PANOMIX_OTCML-2023
代谢物信息卡片
5,7-Dihydroxyisoflavone
化学式: C15H10O4 (254.057906)
中文名称:
谱图信息:
最多检出来源 Viridiplantae(plant) 2.78%
分子结构信息
SMILES: C1(O)C=C(O)C2C(=O)C(C3=CC=CC=C3)=COC=2C=1
InChI: InChI=1S/C15H10O4/c16-10-6-12(17)14-13(7-10)19-8-11(15(14)18)9-4-2-1-3-5-9/h1-8,16-17H
描述信息
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:174348
- PubChem: 5377381
- Metlin: METLIN47672
- ChEMBL: CHEMBL1488393
- LipidMAPS: LMPK12050160
- MeSH: Mefenamic Acid
- CAS: 4044-00-2
- MoNA: Bruker_HCD_library000416
- MoNA: VF-NPL-LTQ007200
- MoNA: VF-NPL-LTQ007199
- MoNA: VF-NPL-LTQ007198
- MoNA: VF-NPL-LTQ007197
- MoNA: VF-NPL-QEHF014037
- MoNA: VF-NPL-QEHF014036
- MoNA: VF-NPL-QEHF014035
- MoNA: VF-NPL-QEHF014034
- MoNA: VF-NPL-QEHF014033
- MoNA: VF-NPL-QEHF014032
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 37501 Maackia amurensis: 10.1007/BF00576208
- 37501 Maackia amurensis: 10.1007/BF00576208
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jose Guzman-Esquivel, Hector R Galvan-Salazar, Hannah P Guzman-Solorzano, Andrea C Cuevas-Velazquez, Jose A Guzman-Solorzano, Karen A Mokay-Ramirez, Brenda A Paz-Michel, Efren Murillo-Zamora, Josuel Delgado-Enciso, Valery Melnikov, Osiris G Delgado-Enciso, Iram P Rodriguez-Sanchez, Margarita L Martinez-Fierro, Fabian Rojas-Larios, Mireya Walle-Guillen, Citlaly B Cardenas-Aguilar, Oscar Beas-Guzman, Daniel Chaviano-Conesa, Hossana S Garcia-Garcia, Ivan Delgado-Enciso. Efficacy of the use of mefenamic acid combined with standard medical care vs. standard medical care alone for the treatment of COVID‑19: A randomized double‑blind placebo‑controlled trial.
International journal of molecular medicine.
2022 Mar; 49(3):. doi:
10.3892/ijmm.2022.5084. [PMID: 35029292] - Dounia Sid, Milad Baitiche, Zineb Elbahri, Ferhat Djerboua, Mokhtar Boutahala, Zouhair Bouaziz, Marc Le Borgne. Solubility enhancement of mefenamic acid by inclusion complex with β-cyclodextrin: in silico modelling, formulation, characterisation, and in vitro studies.
Journal of enzyme inhibition and medicinal chemistry.
2021 Dec; 36(1):605-617. doi:
10.1080/14756366.2020.1869225. [PMID: 33557644] - Yan Rong, Tony K L Kiang. Characterization of human sulfotransferases catalyzing the formation of p-cresol sulfate and identification of mefenamic acid as a potent metabolism inhibitor and potential therapeutic agent for detoxification.
Toxicology and applied pharmacology.
2021 08; 425(?):115553. doi:
10.1016/j.taap.2021.115553. [PMID: 33915121] - Rami Ayoub, Qais Jarrar, Dalia Ali, Said Moshawih, Yazun Jarrar, Muhammad Hakim, Zainul Zakaria. Synthesis of Novel Esters of Mefenamic Acid with Pronounced Anti-nociceptive Effects and a Proposed Activity on GABA, Opioid and Glutamate Receptors.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2021 Aug; 163(?):105865. doi:
10.1016/j.ejps.2021.105865. [PMID: 33979659] - Fatemeh Darvishnejad, Jahan Bakhsh Raoof, Milad Ghani. In-situ synthesis of nanocubic cobalt oxide @ graphene oxide nanocomposite reinforced hollow fiber-solid phase microextraction for enrichment of non-steroidal anti-inflammatory drugs from human urine prior to their quantification via high-performance liquid chromatography-ultraviolet detection.
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CPT: pharmacometrics & systems pharmacology.
2021 02; 10(2):127-136. doi:
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2020 Apr; 1142(?):122039. doi:
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2020 Jan; 44(1):130-140. doi:
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Chemosphere.
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2019 Jun; 44(?):102-109. doi:
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