butalbital (BioDeep_00000406268)
Volatile Flavor Compounds
代谢物信息卡片
butalbital
化学式: C11H16N2O3 (224.1160866)
中文名称: 异丁烯丙巴比妥
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=CCC1(CC(C)C)C(=O)NC(=O)NC1=O
InChI: InChI=1S/C11H16N2O3/c1-4-5-11(6-7(2)3)8(14)12-10(16)13-9(11)15/h4,7H,1,5-6H2,2-3H3,(H2,12,13,14,15,16)
描述信息
C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C67084 - Barbiturate
同义名列表
2 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:102524
- KEGGdrug: D03182
- PubChem: 2481
- Metlin: METLIN3941
- DrugBank: DB00241
- ChEMBL: CHEMBL454
- CAS: 77-26-9
- MoNA: FiehnHILIC002623
- RefMet: Butalbital
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Janelle O Poyant, Robert Albright, Jeremy Clain, Govind Pandompatam, Erin F Barreto. Extracorporeal elimination of butalbital in acute aspirin-butalbital-caffeine-codeine (Fiorinal with Codeine) poisoning.
Clinical toxicology (Philadelphia, Pa.).
2018 06; 56(6):439-441. doi:
10.1080/15563650.2017.1400554. [PMID: 29124988] - Anna Ferrari, Ilaria Tiraferri, Federica Palazzoli, Patrizia Verri, Daniele Vandelli, Filippo Marchesi, Michela Ciccarese, Manuela Licata. Hair analysis to monitor abuse of analgesic combinations containing butalbital and propyphenazone.
Journal of pharmaceutical and biomedical analysis.
2015 Nov; 115(?):576-9. doi:
10.1016/j.jpba.2015.08.015. [PMID: 26319751] - Dean Fritch, Kristen Blum, Sheena Nonnemacher, Keith Kardos, August R Buchhalter, Edward J Cone. Barbiturate detection in oral fluid, plasma, and urine.
Therapeutic drug monitoring.
2011 Feb; 33(1):72-9. doi:
10.1097/ftd.0b013e3182018151. [PMID: 21099741] - Patrick J Phillips, Steven G Smith, D W Kolpin, Steven D Zaugg, Herbert T Buxton, Edward T Furlong, Kathleen Esposito, Beverley Stinson. Pharmaceutical formulation facilities as sources of opioids and other pharmaceuticals to wastewater treatment plant effluents.
Environmental science & technology.
2010 Jul; 44(13):4910-6. doi:
10.1021/es100356f. [PMID: 20521847] - Leonard L Johnson, Uttam Garg. Quantitation of amobarbital, butalbital, pentobarbital, phenobarbital, and secobarbital in urine, serum, and plasma using gas chromatography-mass spectrometry (GC-MS).
Methods in molecular biology (Clifton, N.J.).
2010; 603(?):65-74. doi:
10.1007/978-1-60761-459-3_7. [PMID: 20077060] - D Blake Woodside, Patricia Colton, Randolf Staab, Martin Schreiber, Kalam Sutandar-Pinnock, Brittany Poynter, Tegan Sacevich. Weight restoration in a patient with anorexia nervosa on dialysis.
The International journal of eating disorders.
2005 Dec; 38(4):380-2. doi:
10.1002/eat.20191. [PMID: 16261601] - Inderpreet Sekhon, Sandeep Munjal, Byron Croker, Richard J Johnson, A Ahsan Ejaz. Glomerular tip lesion associated with nonsteroidal anti-inflammatory drug-induced nephrotic syndrome.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2005 Oct; 46(4):e55-8. doi:
10.1053/j.ajkd.2005.05.034. [PMID: 16183408] - C Pistos, J T Stewart. Assay for the simultaneous determination of acetaminophen-caffeine-butalbital in human serum using a monolithic column.
Journal of pharmaceutical and biomedical analysis.
2004 Nov; 36(4):737-41. doi:
10.1016/j.jpba.2004.07.042. [PMID: 15533665] - Karla A Moore, Tasha L Zemrus, Vera Ramcharitar, Barry Levine, David R Fowler. Mixed drug intoxication involving zaleplon ('Sonata').
Forensic science international.
2003 Jul; 134(2-3):120-2. doi:
10.1016/s0379-0738(03)00130-0. [PMID: 12850405] - Russell J Lewis, Robert D Johnson, Travis L Southern, Dennis V Canfield. Distribution of butalbital in postmortem tissues and fluids from non-overdose cases.
Journal of analytical toxicology.
2003 Apr; 27(3):145-8. doi:
10.1093/jat/27.3.145. [PMID: 12731655] - M M Kushnir, F M Urry. Use of a statistically designed experimental approach to optimize the propylketal derivatization of barbiturates.
Journal of chromatographic science.
2001 Apr; 39(4):129-36. doi:
10.1093/chromsci/39.4.129. [PMID: 11318064] - R D Cannon, S H Wong, S B Gock, J J Jentzen. Comparison of the serum barbiturate fluorescence polarization immunoassay by the COBAS INTEGRA to a GC/MS method.
Therapeutic drug monitoring.
1999 Oct; 21(5):553-8. doi:
10.1097/00007691-199910000-00012. [PMID: 10519455] - J C Spell, K Srinivasan, J T Stewart, M G Bartlett. Supercritical fluid extraction and negative ion electrospray liquid chromatography tandem mass spectrometry analysis of phenobarbital, butalbital, pentobarbital and thiopental in human serum.
Rapid communications in mass spectrometry : RCM.
1998; 12(13):890-4. doi:
10.1002/(sici)1097-0231(19980715)12:13<890::aid-rcm251>3.0.co;2-x. [PMID: 9684381] - S P Nordt. Butalbital cross-reactivity to an Emit assay for phenobarbital.
The Annals of pharmacotherapy.
1997 Feb; 31(2):254-5. doi:
10.1177/106002809703100225. [PMID: 9034435] - R H Liu, A M McKeehan, C Edwards, G Foster, W D Bensley, J G Langner, A S Walia. Improved gas chromatography/mass spectrometry analysis of barbiturates in urine using centrifuge-based solid-phase extraction, methylation, with d5-pentobarbital as internal standard.
Journal of forensic sciences.
1994 Nov; 39(6):1504-14. doi:
NULL. [PMID: 7815030] - M L Drost, L Walter. Blood and plasma concentrations of butalbital following single oral doses in man.
Journal of analytical toxicology.
1988 Nov; 12(6):322-4. doi:
10.1093/jat/12.6.322. [PMID: 3244271] - J G Dain, S I Bhuta, R A Coombs, K C Talbot, H A Dugger. Metabolism of butalbital, 5-allyl-5-isobutylbarbituric acid, in the dog.
Drug metabolism and disposition: the biological fate of chemicals.
1980 Jul; 8(4):247-52. doi:
NULL. [PMID: 6105059] - A W Mondorf. [Evidence of urinary tubular proteins in inflammatory and toxic kidney damage].
Wiener medizinische Wochenschrift. Supplement.
1975; 27(?):20-3. doi:
NULL. [PMID: 5816]