benzbromarone (BioDeep_00000406116)
代谢物信息卡片
benzbromarone
化学式: C17H12Br2O3 (421.9153122)
中文名称: 苯溴马隆
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br
InChI: InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
描述信息
M - Musculo-skeletal system > M04 - Antigout preparations > M04A - Antigout preparations > M04AB - Preparations increasing uric acid excretion
D018501 - Antirheumatic Agents > D006074 - Gout Suppressants > D014528 - Uricosuric Agents
C26170 - Protective Agent > C921 - Uricosuric Agent
同义名列表
1 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:3023
- KEGGdrug: D01056
- PubChem: 2333
- DrugBank: DB12319
- ChEMBL: CHEMBL388590
- MeSH: Benzbromarone
- CAS: 3562-84-3
- MoNA: FiehnHILIC002612
- MoNA: FiehnHILIC001087
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- C-Q Yan, C Liang, Z-R Lan, C Su, S-Y Xiong, Y-X Yang, J-M Chen, S-L Tang, J-S Huang, Z-H Zhang, M-J Luo, Z-H Xiao. Comparison of the efficacy of febuxostat vs. benzbromarone in the treatment of gout: a meta-analysis in Chinese gout patients.
European review for medical and pharmacological sciences.
2023 Dec; 27(24):11988-12003. doi:
10.26355/eurrev_202312_34797. [PMID: 38164861] - Yanfen Niu, Qiang Li, Caixia Tu, Na Li, Lihui Gao, Hua Lin, Zhenyu Wang, Zhihong Zhou, Ling Li. Hypouricemic Actions of the Pericarp of Mangosteen in Vitro and in Vivo.
Journal of natural products.
2023 01; 86(1):24-33. doi:
10.1021/acs.jnatprod.2c00531. [PMID: 36634312] - Yu-Kai Zhang, Jia-Shu Chen, Min-Min Wang, Chuan-Zeng Wang, Mu-Xuan Wang, Zhen Wang, Qin-Liang Yang, Bin Sun, Jin-Yue Sun, Yu-Fa Liu, Chao Liu. Synthesis and bioactivity evaluation of novel nuciferine derivatives with antihyperuricemia and nephroprotective effects.
Bioorganic chemistry.
2022 09; 126(?):105916. doi:
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Clinical rheumatology.
2022 Jul; 41(7):2121-2128. doi:
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Journal of molecular modeling.
2022 Jun; 28(7):193. doi:
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International journal of clinical pharmacology and therapeutics.
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Journal of separation science.
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Diabetes.
2019 05; 68(5):1014-1025. doi:
10.2337/db18-0912. [PMID: 30728185] - Xiaolan Ye, Jian Wu, Kun Tang, Wenge Li, Cunquan Xiong, Li Zhuo. Benzbromarone as a possible cause of acute kidney injury in patients with urolithiasis: Two case reports.
Medicine.
2019 Apr; 98(15):e15214. doi:
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2015 Apr; 98 Suppl 3(?):S46-50. doi:
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2015; 38(3):487-92. doi:
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2015; 37(4):1491-502. doi:
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2014 Jan; 137(1):189-211. doi:
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2014; 37(12):1866-71. doi:
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