Pefloxacin (BioDeep_00000405979)
代谢物信息卡片
Pefloxacin
化学式: C17H20FN3O3 (333.14886220000005)
中文名称: 培氟沙星
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O
InChI: InChI=1S/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24)
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials > J01MA - Fluoroquinolones
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065609 - Cytochrome P-450 CYP1A2 Inhibitors
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
同义名列表
1 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:50199
- KEGGdrug: D02306
- PubChem: 51081
- DrugBank: DB00487
- ChEMBL: CHEMBL267648
- MeSH: Pefloxacin
- CAS: 70458-92-3
- MoNA: FiehnHILIC002230
- MoNA: FiehnHILIC000662
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Junjun Feng, Haiyun Jiang, Jing Wang, Zhengyi Jing, Fan Zhang, Tianyu Tan, Feng He, Lihua Jiang, Haiqin Li, Shimin Chang, Tengfei Li. [Simultaneous determination of 40 plant growth regulators, fungicides, insecticides, and antibiotics in bean sprouts by QuEChERS-high performance liquid chromatography-tandem mass spectrometry].
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2022 Sep; 40(9):843-853. doi:
10.3724/sp.j.1123.2021.12028. [PMID: 36156631] - Wanling Cai, Xiulan Weng, Wei Zhang, Zuliang Chen. Green magnetic nanomaterial as antibiotic release vehicle: The release of pefloxacin and ofloxacin.
Materials science & engineering. C, Materials for biological applications.
2021 Jan; 118(?):111439. doi:
10.1016/j.msec.2020.111439. [PMID: 33255032] - Sivaramakrishnan Ramadurai, Nirod Kumar Sarangi, Sean Maher, Nicola MacConnell, Alan M Bond, Dennis McDaid, Damien Flynn, Tia E Keyes. Microcavity-Supported Lipid Bilayers; Evaluation of Drug-Lipid Membrane Interactions by Electrochemical Impedance and Fluorescence Correlation Spectroscopy.
Langmuir : the ACS journal of surfaces and colloids.
2019 06; 35(24):8095-8109. doi:
10.1021/acs.langmuir.9b01028. [PMID: 31120755] - Xiuyuan Zhang, Kuo He, Donghao Zhang, Zhihong Huang. Production and characterization of a monoclonal antibody for Pefloxacin and mechanism study of antibody recognition.
Bioscience, biotechnology, and biochemistry.
2019 Apr; 83(4):633-640. doi:
10.1080/09168451.2018.1562876. [PMID: 30618329] - Lei Sha, Xiaoyan Tang, Dengyong Liu, Yongping Xu, Y U Ding, Feng Ding. Detection and Quantitation of Lomefloxacin and Pefloxacin Residues in the Organ Tissues and Eggs of Laying Hens.
Journal of food protection.
2018 05; 81(5):810-814. doi:
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Biomedical chromatography : BMC.
2018 Apr; 32(4):. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2017 04; 45(4):399-408. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
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Journal of clinical microbiology.
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Pakistan journal of pharmaceutical sciences.
2014 Mar; 27(2):389-95. doi:
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2011 May; 11(2):91-6. doi:
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2010 Aug; 11(?):19. doi:
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Die Pharmazie.
2010 Apr; 65(4):284-9. doi:
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2009 Dec; 10(4):293-7. doi:
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2009 Aug; 877(24):2585-8. doi:
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Journal of Korean medical science.
2008 Dec; 23(6):982-7. doi:
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Berliner und Munchener tierarztliche Wochenschrift.
2008 Nov; 121(11-12):432-9. doi:
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
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European journal of drug metabolism and pharmacokinetics.
2008 Jul; 33(3):173-9. doi:
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2008 Jul; 36(7):1385-405. doi:
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Journal of veterinary science.
2008 Mar; 9(1):25-9. doi:
10.4142/jvs.2008.9.1.25. [PMID: 18296885] - Bengi Uslu, Burcu Dogan Topal, Sibel A Ozkan. Electroanalytical investigation and determination of pefloxacin in pharmaceuticals and serum at boron-doped diamond and glassy carbon electrodes.
Talanta.
2008 Feb; 74(5):1191-200. doi:
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Pediatric nephrology (Berlin, Germany).
2007 Oct; 22(10):1723-6. doi:
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Medecine et maladies infectieuses.
2007 Feb; 37(2):103-7. doi:
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2006 Dec; 22(12):1515-8. doi:
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Environmental toxicology and pharmacology.
2006 Sep; 22(2):167-71. doi:
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2006 Jun; 7(6):452-8. doi:
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Archives of environmental contamination and toxicology.
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British poultry science.
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