Diphenylcyclopropenone (BioDeep_00000405807)
代谢物信息卡片
化学式: C15H10O (206.073161)
中文名称: 二苯基环丙烯酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)C2=C(C2=O)C3=CC=CC=C3
InChI: InChI=1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H
描述信息
C308 - Immunotherapeutic Agent > C2139 - Immunostimulant
同义名列表
2 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:53074
- PubChem: 65057
- DrugBank: DB12173
- ChEMBL: CHEMBL1373467
- CAS: 40736-43-4
- CAS: 886-38-4
- MoNA: FiehnHILIC001891
- MoNA: FiehnHILIC000314
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Louise S Cunningham, John P McFadden, David A Basketter, Felicity J Ferguson, Ian R White, Ian Kimber. Harnessing co-operative immune augmentation by contact allergens to enhance the efficacy of viral vaccines.
Contact dermatitis.
2020 Nov; 83(5):432-435. doi:
10.1111/cod.13685. [PMID: 32880961] - Yugang Gong, Ying Zhao, Xiaoting Zhang, Shiling Qi, Shuifeng Li, Yanting Ye, Jian Yang, Sillani Caulloo, Kevin J McElwee, Xingqi Zhang. Serum level of IL-4 predicts response to topical immunotherapy with diphenylcyclopropenone in alopecia areata.
Experimental dermatology.
2020 03; 29(3):231-238. doi:
10.1111/exd.13758. [PMID: 30047620] - Erika Parkinson, Maja Aleksic, Rachael Arthur, Sergio Regufe Da Mota, Richard Cubberley, Paul J Skipp. Proteomic analysis of haptenation by skin sensitisers: Diphencyprone and ethyl acrylate.
Toxicology in vitro : an international journal published in association with BIBRA.
2020 Feb; 62(?):104697. doi:
10.1016/j.tiv.2019.104697. [PMID: 31669365] - Yun Tao, Yinzhu Shang, Jing Li, Jingwen Feng, Zhenyu He, Adrian Covaci, Peng Wang, Jing Luo, Xiang Mao, Bin Shi, Liqin Hu, Dan Luo, Surong Mei. Exposure to organophosphate flame retardants of hotel room attendants in Wuhan City, China.
Environmental pollution (Barking, Essex : 1987).
2018 May; 236(?):626-633. doi:
10.1016/j.envpol.2018.01.079. [PMID: 29433103] - Giulia Ganzetti, Oriana Simonetti, Anna Campanati, Katia Giuliodori, Vitangelo Scocco, Marina Brugia, Massimo Tocchini, Anamaria Offidani. Osteopontin: a new facilitating factor in alopecia areata pathogenesis?.
Acta dermatovenerologica Croatica : ADC.
2015; 23(1):19-22. doi:
NULL. [PMID: 25969908] - Ibrahim A Aljuffali, Calvin T Sung, Feng-Ming Shen, Chi-Ting Huang, Jia-You Fang. Squarticles as a lipid nanocarrier for delivering diphencyprone and minoxidil to hair follicles and human dermal papilla cells.
The AAPS journal.
2014 Jan; 16(1):140-50. doi:
10.1208/s12248-013-9550-y. [PMID: 24307611] - Yin-Ku Lin, Saleh A Al-Suwayeh, Yann-Lii Leu, Feng-Ming Shen, Jia-You Fang. Squalene-containing nanostructured lipid carriers promote percutaneous absorption and hair follicle targeting of diphencyprone for treating alopecia areata.
Pharmaceutical research.
2013 Feb; 30(2):435-46. doi:
10.1007/s11095-012-0888-0. [PMID: 23070602] - Ji Young Ahn, Sun Eun Choi, Mi Sook Jeong, Kwan Hee Park, Nam Ju Moon, Seong Soo Joo, Chung Soo Lee, Young Wook Choi, Kapsok Li, Mi-Kyung Lee, Min Won Lee, Seong Jun Seo. Effect of taxifolin glycoside on atopic dermatitis-like skin lesions in NC/Nga mice.
Phytotherapy research : PTR.
2010 Jul; 24(7):1071-7. doi:
10.1002/ptr.3084. [PMID: 20041431] - Desmond J Tobin, Sarah H Gardner, Nigel J Lindsey, Rolf Hoffmann, Rudolf Happle, Pia Freyschmidt-Paul. Diphencyprone immunotherapy alters anti-hair follicle antibody status in patients with alopecia areata.
European journal of dermatology : EJD.
2002 Jul; 12(4):327-34. doi:
NULL. [PMID: 12095876] - C E Griffiths, M Cumberbatch, S C Tucker, R J Dearman, S Andrew, D R Headon, I Kimber. Exogenous topical lactoferrin inhibits allergen-induced Langerhans cell migration and cutaneous inflammation in humans.
The British journal of dermatology.
2001 Apr; 144(4):715-25. doi:
10.1046/j.1365-2133.2001.04125.x. [PMID: 11298528] - M Pericin, R M Trüeb. Topical immunotherapy of severe alopecia areata with diphenylcyclopropenone: evaluation of 68 cases.
Dermatology (Basel, Switzerland).
1998; 196(4):418-21. doi:
10.1159/000017935. [PMID: 9669118] - J Berth-Jones, A Mc Burney, P E Hutchinson. Diphencyprone is not detectable in serum or urine following topical application.
Acta dermato-venereologica.
1994 Jul; 74(4):312-3. doi:
10.2340/0001555574312313. [PMID: 7976097]