5-Phenylvaleric acid (BioDeep_00000405502)
Secondary id: BioDeep_00000027749
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C11H14O2 (178.09937440000002)
中文名称: 5-苯基戊酸
谱图信息:
最多检出来源 Viridiplantae(plant) 0.14%
分子结构信息
SMILES: C1=CC=C(C=C1)CCCCC(=O)O
InChI: InChI=1S/C11H14O2/c12-11(13)9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9H2,(H,12,13)
描述信息
5-Phenylvaleric acid (5-Phenylpentanoic acid) is a pentanoic acid of bacterial origin, occasionally found in human biofluids.
同义名列表
2 个代谢物同义名
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:40131
- PubChem: 16757
- Metlin: METLIN6456
- DrugBank: DB04051
- ChEMBL: CHEMBL443064
- CAS: 2270-20-4
- MoNA: MoNA038235
- MoNA: MoNA037482
- MoNA: MoNA035219
- MoNA: MoNA035218
- MoNA: MoNA035215
- MoNA: MoNA032667
- MoNA: MoNA032665
- MoNA: MoNA032664
- MoNA: HMDB0002043_ms_ms_1966
- MoNA: HMDB0002043_ms_ms_1967
- MoNA: HMDB0002043_ms_ms_1965
- RefMet: 5-Phenylvaleric acid
- medchemexpress: HY-W032915
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Donato Angelino, Diogo Carregosa, Cristina Domenech-Coca, Monia Savi, Inês Figueira, Nicoletta Brindani, Saebyeol Jang, Sukla Lakshman, Aleksey Molokin, Joseph F Urban, Cindy D Davis, Maria Alexandra Brito, Kwang Sik Kim, Furio Brighenti, Claudio Curti, Cinta Bladé, Josep M Del Bas, Donatella Stilli, Gloria I Solano-Aguilar, Claudia Nunes Dos Santos, Daniele Del Rio, Pedro Mena. 5-(Hydroxyphenyl)-γ-Valerolactone-Sulfate, a Key Microbial Metabolite of Flavan-3-ols, Is Able to Reach the Brain: Evidence from Different in Silico, In Vitro and In Vivo Experimental Models.
Nutrients.
2019 Nov; 11(11):. doi:
10.3390/nu11112678. [PMID: 31694297] - Pedro Mena, Letizia Bresciani, Nicoletta Brindani, Iziar A Ludwig, Gema Pereira-Caro, Donato Angelino, Rafael Llorach, Luca Calani, Furio Brighenti, Michael N Clifford, Chris I R Gill, Alan Crozier, Claudio Curti, Daniele Del Rio. Phenyl-γ-valerolactones and phenylvaleric acids, the main colonic metabolites of flavan-3-ols: synthesis, analysis, bioavailability, and bioactivity.
Natural product reports.
2019 05; 36(5):714-752. doi:
10.1039/c8np00062j. [PMID: 30468210] - S Jakobtorweihen, A Chaides Zuniga, T Ingram, T Gerlach, F J Keil, I Smirnova. Predicting solute partitioning in lipid bilayers: Free energies and partition coefficients from molecular dynamics simulations and COSMOmic.
The Journal of chemical physics.
2014 Jul; 141(4):045102. doi:
10.1063/1.4890877. [PMID: 25084963] - Marta Zamarbide, Eva Martinez-Pinilla, Ana Ricobaraza, Tomás Aragón, Rafael Franco, Alberto Pérez-Mediavilla. Phenyl acyl acids attenuate the unfolded protein response in tunicamycin-treated neuroblastoma cells.
PloS one.
2013; 8(8):e71082. doi:
10.1371/journal.pone.0071082. [PMID: 23976981] - Seisuke Mimori, Yasunobu Okuma, Masayuki Kaneko, Koichi Kawada, Toru Hosoi, Koichiro Ozawa, Yasuyuki Nomura, Hiroshi Hamana. Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress.
Biological & pharmaceutical bulletin.
2012; 35(1):84-90. doi:
10.1248/bpb.35.84. [PMID: 22223342] - Maura N Laus, Mario Soccio, Daniela Trono, Maria T Liberatore, Donato Pastore. Activation of the plant mitochondrial potassium channel by free fatty acids and acyl-CoA esters: a possible defence mechanism in the response to hyperosmotic stress.
Journal of experimental botany.
2011 Jan; 62(1):141-54. doi:
10.1093/jxb/erq256. [PMID: 20801915] - Kristian Tveten, Øystein L Holla, Trine Ranheim, Knut E Berge, Trond P Leren, Mari A Kulseth. 4-Phenylbutyrate restores the functionality of a misfolded mutant low-density lipoprotein receptor.
The FEBS journal.
2007 Apr; 274(8):1881-93. doi:
10.1111/j.1742-4658.2007.05735.x. [PMID: 17408384] - Marie-Paule Gonthier, Jennifer L Donovan, Odile Texier, Catherine Felgines, Christian Remesy, Augustin Scalbert. Metabolism of dietary procyanidins in rats.
Free radical biology & medicine.
2003 Oct; 35(8):837-44. doi:
10.1016/s0891-5849(03)00394-0. [PMID: 14556848] - Adolfo G Garcia-Pérez, José Barril, Jorge Estévez, Eugenio Vilanova. Properties of phenyl valerate esterase activities from chicken serum are comparable with soluble esterases of peripheral nerves in relation with organophosphorus compounds inhibition.
Toxicology letters.
2003 Apr; 142(1-2):1-10. doi:
10.1016/s0378-4274(02)00469-1. [PMID: 12765233] - G Petroianu, B Kärcher, N Kern, W Bergler, R Rüfer. Paraoxon sensitive phenylvalerate hydrolase in assessing the severity of acute paraoxon poisoning.
Journal of toxicology. Clinical toxicology.
2001; 39(1):27-31. doi:
10.1081/clt-100102876. [PMID: 11327223] - L Giuliani, G Carmignani, E Belgrano, P Puppo. Transcatheter arterial embolization in urological tumors: the use of isobutyl-2-cyanoacrylate.
The Journal of urology.
1979 May; 121(5):630-4. doi:
10.1016/s0022-5347(17)56913-x. [PMID: 439260]