Vanillactic acid (BioDeep_00000405400)
代谢物信息卡片
Vanillactic acid
化学式: C10H12O5 (212.0685)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=C(C=CC(=C1)CC(C(=O)O)O)O
InChI: InChI=1S/C10H12O5/c1-15-9-5-6(2-3-7(9)11)4-8(12)10(13)14/h2-3,5,8,11-12H,4H2,1H3,(H,13,14)
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:88526
- PubChem: 160637
- Metlin: METLIN5868
- ChEMBL: CHEMBL1765649
- CAS: 2475-56-1
- MoNA: HMDB0000913_ms_ms_1302
- MoNA: HMDB0000913_ms_ms_1300
- MoNA: HMDB0000913_ms_ms_1301
- RefMet: Vanillactic acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Heiko Brennenstuhl, Sven F Garbade, Jürgen G Okun, Patrik Feyh, Georg F Hoffmann, Claus-Dieter Langhans, Thomas Opladen. Semi-quantitative detection of a vanillactic acid/vanillylmandelic acid ratio in urine is a reliable diagnostic marker for aromatic L-amino acid decarboxylase deficiency.
Molecular genetics and metabolism.
2020 Sep; 131(1-2):163-170. doi:
10.1016/j.ymgme.2020.07.001. [PMID: 32675002] - Han Li, Mu Wang, Qiande Liang, Shuna Jin, Xiaojie Sun, Yangqian Jiang, Xingyun Pan, Yanqiu Zhou, Yang Peng, Bin Zhang, Aifen Zhou, Yiming Zhang, Zhong Chen, Jiangxia Cao, Hongling Zhang, Wei Xia, Tongzhang Zheng, Zongwei Cai, Yuanyuan Li, Shunqing Xu. Urinary metabolomics revealed arsenic exposure related to metabolic alterations in general Chinese pregnant women.
Journal of chromatography. A.
2017 Jan; 1479(?):145-152. doi:
10.1016/j.chroma.2016.12.007. [PMID: 27988079] - Zhishan Li, Alcmène Chalazonitis, Yung-Yu Huang, J John Mann, Kara Gross Margolis, Qi Melissa Yang, Dolly O Kim, Francine Côté, Jacques Mallet, Michael D Gershon. Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2011 Jun; 31(24):8998-9009. doi:
10.1523/jneurosci.6684-10.2011. [PMID: 21677183] - Angeles Ruiz, Judit García-Villoria, Aida Ormazabal, Johannes Zschocke, Miquel Fiol, Aleix Navarro-Sastre, Rafael Artuch, Maria Antonia Vilaseca, Antonia Ribes. A new fatal case of pyridox(am)ine 5'-phosphate oxidase (PNPO) deficiency.
Molecular genetics and metabolism.
2008 Feb; 93(2):216-8. doi:
10.1016/j.ymgme.2007.10.003. [PMID: 18024216] - Jose E Abdenur, Nico Abeling, Norma Specola, Lia Jorge, Andrea B Schenone, Arno C van Cruchten, Nestor A Chamoles. Aromatic l-aminoacid decarboxylase deficiency: unusual neonatal presentation and additional findings in organic acid analysis.
Molecular genetics and metabolism.
2006 Jan; 87(1):48-53. doi:
10.1016/j.ymgme.2005.09.007. [PMID: 16288991] - F Mashige, A Ohkubo, Y Matsushima, M Takano, E Tsuchiya, H Kanazawa, Y Nagata, N Takai, N Shinozuka, I Sakuma. High-performance liquid chromatographic determination of catecholamine metabolites and 5-hydroxyindoleacetic acid in human urine using a mixed-mode column and an eight-channel electrode electrochemical detector.
Journal of chromatography. B, Biomedical applications.
1994 Aug; 658(1):63-8. doi:
10.1016/0378-4347(94)00227-4. [PMID: 7524950] - K Hyland, P T Clayton. Aromatic L-amino acid decarboxylase deficiency: diagnostic methodology.
Clinical chemistry.
1992 Dec; 38(12):2405-10. doi:
10.1093/clinchem/38.12.2405. [PMID: 1281049] - J Jouve, D Bakri, J Herault, J P Muh. Determination of urinary vanillactic acid and plasma dihydroxyphenylalanine as markers of non-secreting neuroblastoma by high-performance liquid chromatography with electrochemical detection.
Journal of chromatography.
1991 Jul; 567(2):331-41. doi:
10.1016/0378-4347(91)80139-4. [PMID: 1939466] - C N Ong, K S Chia, D Koh, K Saijoh. Neurochemical effect of lead exposure: a study on catecholamine metabolism.
American journal of industrial medicine.
1989; 16(6):667-73. doi:
10.1002/ajim.4700160606. [PMID: 2596488] - Y Kinoshita, S Yamada, K Haraguchi, T Takayanagi, Y Mori, T Takahashi, E Haruki. Determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid in dried urine on filter-paper discs by high-performance liquid chromatography with coulometric electrochemical detection for neuroblastoma screening.
Clinical chemistry.
1988 Nov; 34(11):2228-30. doi:
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Pediatric research.
1988 Jun; 23(6):576-9. doi:
10.1203/00006450-198806000-00009. [PMID: 3393388] - S Higa, S Kishimoto. Isolation of 2-hydroxycarboxylic acids with a boronate affinity gel.
Analytical biochemistry.
1986 Apr; 154(1):71-4. doi:
10.1016/0003-2697(86)90497-5. [PMID: 3706738] - J R Rajnherc, A H van Gennip, N G Abeling, J M van der Zee, P A Voûte. Cystathioninuria in patients with neuroblastoma.
Medical and pediatric oncology.
1984; 12(2):81-4. doi:
10.1002/mpo.2950120203. [PMID: 6422219] - P W Banda, M S Tuttle, L E Selmer, Y T Thatachari, A E Sherry, M S Blois. Data processing of urine chromatograms for the clinical management of melanoma.
Computers and biomedical research, an international journal.
1980 Dec; 13(6):549-66. doi:
10.1016/0010-4809(80)90033-6. [PMID: 6780261] - F A Muskiet, D C Fremouw-Ottevangers, J van der Meulen, B G Wolthers, J A de Vries. Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
Clinical chemistry.
1978 Jan; 24(1):122-7. doi:
NULL. [PMID: 73430] - S K Wadman, D Ketting, P A Voûte. Gas chromatographic determination of urinary vanilglycolic acid, vanilglycol, vanilacetic acid and vanillactic acid-chemical parameters for the diagnosis of neurogenic tumours and the evaluation of their treatment.
Clinica chimica acta; international journal of clinical chemistry.
1976 Oct; 72(1):49-68. doi:
10.1016/0009-8981(76)90036-x. [PMID: 184988] - K B CHOREMIS, N S CONSTANTSAS, C DANELATOS-ATHANASSIADIS, A S AGATHOPOULOS. METABOLISM OF AROMATIC AMINO ACIDS IN COLLAGEN DISEASES. URINARY EXCRETION OF VANILLACTIC ACID AND DIHYDROXYPHENYLALANINE.
Clinica chimica acta; international journal of clinical chemistry.
1964 Dec; 10(?):489-95. doi:
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