7-Methylguanine (BioDeep_00000405395)
Main id: BioDeep_00000002254
代谢物信息卡片
7-Methylguanine
化学式: C6H7N5O (165.0650572)
中文名称: 7-甲基鸟嘌呤
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C=NC2=C1C(=O)N=C(N)N2
InChI: InChI=1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12)
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:28664
- ChEBI: CHEBI:46897
- ChEBI: CHEBI:46894
- KEGG: C02242
- KEGG: C75717
- PubChem: 135398679
- CAS: 578-76-7
- MoNA: HMDB0000897_ms_ms_1270
- MoNA: HMDB0000897_ms_ms_1269
- MoNA: HMDB0000897_ms_ms_1268
- ChEBI: CHEBI:2274
- PubChem: 5305
- PDB-CCD: MY6
- NIKKAJI: J101.566D
- RefMet: 7-Methylguanine
- KNApSAcK: 2274
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jinye Hu, Yuling Bao, Hui Huang, Zhan Zhang, Feng Chen, Lei Li, Qian Wu. The preliminary investigation of potential response biomarkers to PAHs exposure on childhood asthma.
Journal of exposure science & environmental epidemiology.
2022 01; 32(1):82-93. doi:
10.1038/s41370-021-00334-4. [PMID: 33972693] - Barbara Bobrowska-Korczak, Paulina Gątarek, Angelina Rosiak, Joanna Giebułtowicz, Joanna Kałużna-Czaplińska. Reduced levels of modified nucleosides in the urine of autistic children. Preliminary studies.
Analytical biochemistry.
2019 04; 571(?):62-67. doi:
10.1016/j.ab.2019.02.009. [PMID: 30771338] - Ryoko Kawakami, Ikuko Kashino, Hiroshi Kasai, Kazuaki Kawai, Yun-Shan Li, Akiko Nanri, Mitsuru Higuchi, Tetsuya Mizoue. Leisure-time physical activity and DNA damage among Japanese workers.
PloS one.
2019; 14(2):e0212499. doi:
10.1371/journal.pone.0212499. [PMID: 30768632] - Jie-Mei Chu, Tian-Tian Ye, Cheng-Jie Ma, Meng-Dan Lan, Ting Liu, Bi-Feng Yuan, Yu-Qi Feng. Existence of Internal N7-Methylguanosine Modification in mRNA Determined by Differential Enzyme Treatment Coupled with Mass Spectrometry Analysis.
ACS chemical biology.
2018 12; 13(12):3243-3250. doi:
10.1021/acschembio.7b00906. [PMID: 29313662] - Ikuko Kashino, Yun-Shan Li, Kazuaki Kawai, Akiko Nanri, Takako Miki, Shamima Akter, Satomi Kobayashi, Hiroshi Kasai, Tetsuya Mizoue. Dietary non-enzymatic antioxidant capacity and DNA damage in a working population.
Nutrition (Burbank, Los Angeles County, Calif.).
2018 03; 47(?):63-68. doi:
10.1016/j.nut.2017.10.004. [PMID: 29429538] - Casimiro Barbado, Dolores Córdoba-Cañero, Rafael R Ariza, Teresa Roldán-Arjona. Nonenzymatic release of N7-methylguanine channels repair of abasic sites into an AP endonuclease-independent pathway in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America.
2018 01; 115(5):E916-E924. doi:
10.1073/pnas.1719497115. [PMID: 29339505] - Ching-Huang Lai, Han-Bin Huang, Yue-Cune Chang, Ting-Yao Su, Ying-Chuan Wang, Gia-Chi Wang, Jia-En Chen, Chin-Sheng Tang, Trong-Neng Wu, Saou-Hsing Liou. Exposure to fine particulate matter causes oxidative and methylated DNA damage in young adults: A longitudinal study.
The Science of the total environment.
2017 Nov; 598(?):289-296. doi:
10.1016/j.scitotenv.2017.04.079. [PMID: 28445826] - Valentina Klaus, Heinke Bastek, Katja Damme, Leonard B Collins, Roland Frötschl, Norbert Benda, Dominik Lutter, Heidrun Ellinger-Ziegelbauer, James A Swenberg, Daniel R Dietrich, Kerstin Stemmer. Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats.
Archives of toxicology.
2017 Oct; 91(10):3427-3438. doi:
10.1007/s00204-017-1953-6. [PMID: 28349193] - Mu-Rong Chao, Yu-Wen Hsu, Hung-Hsin Liu, Jia-Hong Lin, Chiung-Wen Hu. Simultaneous Detection of 3-Nitrotyrosine and 3-Nitro-4-hydroxyphenylacetic Acid in Human Urine by Online SPE LC-MS/MS and Their Association with Oxidative and Methylated DNA Lesions.
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Journal of applied toxicology : JAT.
2014 Feb; 34(2):176-83. doi:
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Archives of toxicology.
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Proteins.
2013 May; 81(5):896-905. doi:
10.1002/prot.24248. [PMID: 23280611] - Chiung-Wen Hu, Mu-Rong Chao. Direct-acting DNA alkylating agents present in aqueous extracts of areca nut and its products.
Chemical research in toxicology.
2012 Nov; 25(11):2386-92. doi:
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Chemical research in toxicology.
2012 Feb; 25(2):462-70. doi:
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PloS one.
2011 Jan; 6(1):e15873. doi:
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PloS one.
2011; 6(5):e20504. doi:
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PLoS pathogens.
2010 May; 6(5):e1000920. doi:
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Toxicology.
2009 Jun; 260(1-3):1-6. doi:
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Cancer science.
2009 Apr; 100(4):715-21. doi:
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International journal of environmental research and public health.
2009 03; 6(3):874-88. doi:
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Analytical biochemistry.
2008 Dec; 383(2):236-42. doi:
10.1016/j.ab.2008.09.014. [PMID: 18822267] - Mu-Rong Chao, Chien-Jen Wang, Ming-Tsang Wu, Chih-Hong Pan, Chung-Yih Kuo, Hao-Jan Yang, Louis W Chang, Chiung-Wen Hu. Repeated measurements of urinary methylated/oxidative DNA lesions, acute toxicity, and mutagenicity in coke oven workers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2008 Dec; 17(12):3381-9. doi:
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Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2008 Dec; 17(12):3390-5. doi:
10.1158/1055-9965.epi-08-0761. [PMID: 19064555] - Jae Youl Cho, Jongsun Park. Contribution of natural inhibitors to the understanding of the PI3K/PDK1/PKB pathway in the insulin-mediated intracellular signaling cascade.
International journal of molecular sciences.
2008 Nov; 9(11):2217-30. doi:
10.3390/ijms9112217. [PMID: 19330070] - Steffen Loft, Peter Svoboda, Hiroshi Kasai, Anne Tjønneland, Peter Møller, Mette Sørensen, Kim Overvad, Herman Autrup, Ole Raaschou-Nielsen. Prospective study of urinary excretion of 7-methylguanine and the risk of lung cancer: Effect modification by mu class glutathione-S-transferases.
International journal of cancer.
2007 Oct; 121(7):1579-84. doi:
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International archives of occupational and environmental health.
2006 Aug; 79(7):545-9. doi:
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Environmental and molecular mutagenesis.
2006 Mar; 47(2):73-81. doi:
10.1002/em.20168. [PMID: 16106441] - Mu-Rong Chao, Chien-Jen Wang, Hsi-Hsien Yang, Louis W Chang, Chiung-Wen Hu. Rapid and sensitive quantification of urinary N7-methylguanine by isotope-dilution liquid chromatography/electrospray ionization tandem mass spectrometry with on-line solid-phase extraction.
Rapid communications in mass spectrometry : RCM.
2005; 19(17):2427-32. doi:
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Analytical biochemistry.
2004 Nov; 334(2):239-50. doi:
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The Analyst.
2004 Jun; 129(6):535-41. doi:
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Clinica chimica acta; international journal of clinical chemistry.
2003 Sep; 335(1-2):27-32. doi:
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2003; 46(2):179-85. doi:
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The journal of medical investigation : JMI.
2002 Feb; 49(1-2):25-34. doi:
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Cancer research.
2001 Dec; 61(23):8435-40. doi:
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Journal of chromatography. B, Biomedical sciences and applications.
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The journal of medical investigation : JMI.
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Annals of the New York Academy of Sciences.
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Chemico-biological interactions.
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Anticancer research.
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