ligstroside (BioDeep_00000403012)

Main id: BioDeep_00000396572

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


methyl (2S,3E,4S)-3-ethylidene-4-{2-[2-(4-hydroxyphenyl)ethoxy]-2-oxoethyl}-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylate

化学式: C25H32O12 (524.1893672)
中文名称: 女贞甙
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC=C1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)OC)CC(=O)OCCC3=CC=C(C=C3)O
InChI: InChI=1S/C25H32O12/c1-3-15-16(10-19(28)34-9-8-13-4-6-14(27)7-5-13)17(23(32)33-2)12-35-24(15)37-25-22(31)21(30)20(29)18(11-26)36-25/h3-7,12,16,18,20-22,24-27,29-31H,8-11H2,1-2H3

描述信息

同义名列表

3 个代谢物同义名

methyl (2S,3E,4S)-3-ethylidene-4-{2-[2-(4-hydroxyphenyl)ethoxy]-2-oxoethyl}-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-2H-pyran-5-carboxylate; Ligustroside; ligstroside



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ruonan Gao, Yilin Ren, Peng Xue, Yingyue Sheng, Qin Yang, Yuanyuan Dai, Xiaoyue Zhang, Ziming Lin, Tianhao Liu, Yan Geng, Yuzheng Xue. Protective Effect of the Polyphenol Ligustroside on Colitis Induced with Dextran Sulfate Sodium in Mice. Nutrients. 2024 Feb; 16(4):. doi: 10.3390/nu16040522. [PMID: 38398846]
  • Małgorzata Kołtun-Jasion, Paulina Sawulska, Andrzej Patyra, Marta Woźniak, Marta Katarzyna Dudek, Agnieszka Filipek, Anna Karolina Kiss. Bio-Guided Isolation of Compounds from Fraxinus excelsior Leaves with Anti-Inflammatory Activity. International journal of molecular sciences. 2023 Feb; 24(4):. doi: 10.3390/ijms24043750. [PMID: 36835169]
  • Ibtissem Ben Hammouda, Gloria Márquez-Ruiz, Francisca Holgado, Ammar Sonda, Krystyna Skalicka-Wozniak, Mohamed Bouaziz. RP-UHPLC-DAD-QTOF-MS As a Powerful Tool of Oleuropein and Ligstroside Characterization in Olive-Leaf Extract and Their Contribution to the Improved Performance of Refined Olive-Pomace Oil during Heating. Journal of agricultural and food chemistry. 2020 Oct; 68(43):12039-12047. doi: 10.1021/acs.jafc.0c05509. [PMID: 33054204]
  • Rekha Grewal, Martina Reutzel, Benjamin Dilberger, Hannah Hein, Jens Zotzel, Stefan Marx, Joachim Tretzel, Alla Sarafeddinov, Christopher Fuchs, Gunter P Eckert. Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing. Experimental neurology. 2020 06; 328(?):113248. doi: 10.1016/j.expneurol.2020.113248. [PMID: 32084452]
  • Jascha Volk, Alla Sarafeddinov, Turgay Unver, Stefan Marx, Joachim Tretzel, Jens Zotzel, Heribert Warzecha. Two novel methylesterases from Olea europaea contribute to the catabolism of oleoside-type secoiridoid esters. Planta. 2019 Dec; 250(6):2083-2097. doi: 10.1007/s00425-019-03286-0. [PMID: 31578603]
  • M Figueiredo-González, P Reboredo-Rodríguez, C González-Barreiro, A Carrasco-Pancorbo, B Cancho-Grande, J Simal-Gándara. The involvement of phenolic-rich extracts from Galician autochthonous extra-virgin olive oils against the α-glucosidase and α-amylase inhibition. Food research international (Ottawa, Ont.). 2019 02; 116(?):447-454. doi: 10.1016/j.foodres.2018.08.060. [PMID: 30716967]
  • H Miho, C M Díez, A Mena-Bravo, V Sánchez de Medina, J Moral, E Melliou, P Magiatis, L Rallo, D Barranco, F Priego-Capote. Cultivar influence on variability in olive oil phenolic profiles determined through an extensive germplasm survey. Food chemistry. 2018 Nov; 266(?):192-199. doi: 10.1016/j.foodchem.2018.06.002. [PMID: 30381176]
  • Rocío García-Villalba, Francisco A Tomás-Barberán, Pascale Fança-Berthon, Marc Roller, Pilar Zafrilla, Nicolas Issaly, María-Teresa García-Conesa. Targeted and Untargeted Metabolomics to Explore the Bioavailability of the Secoiridoids from a Seed/Fruit Extract (Fraxinus angustifolia Vahl) in Human Healthy Volunteers: A Preliminary Study. Molecules (Basel, Switzerland). 2015 Dec; 20(12):22202-19. doi: 10.3390/molecules201219845. [PMID: 26690403]
  • Konstantina Vougogiannopoulou, Christelle Lemus, Maria Halabalaki, Carlo Pergola, Oliver Werz, Amos B Smith, Sylvie Michel, Leandros Skaltsounis, Brigitte Deguin. One-step semisynthesis of oleacein and the determination as a 5-lipoxygenase inhibitor. Journal of natural products. 2014 Mar; 77(3):441-5. doi: 10.1021/np401010x. [PMID: 24568174]
  • Evangelia Karkoula, Angeliki Skantzari, Eleni Melliou, Prokopios Magiatis. Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers. Journal of agricultural and food chemistry. 2014 Jan; 62(3):600-7. doi: 10.1021/jf404421p. [PMID: 24384036]
  • Stefania Vichi, Nuria Cortés-Francisco, Josep Caixach. Insight into virgin olive oil secoiridoids characterization by high-resolution mass spectrometry and accurate mass measurements. Journal of chromatography. A. 2013 Aug; 1301(?):48-59. doi: 10.1016/j.chroma.2013.05.047. [PMID: 23791146]
  • Jong Hoon Ahn, Eunjin Shin, Qing Liu, Seon Beom Kim, Kyeong-Mi Choi, Hwan-Soo Yoo, Bang Yeon Hwang, Mi Kyeong Lee. Secoiridoids from the stem barks of Fraxinus rhynchophylla with pancreatic lipase inhibitory activity. Natural product research. 2013; 27(12):1132-5. doi: 10.1080/14786419.2012.711328. [PMID: 22840217]
  • Fiammetta Alagna, Roberto Mariotti, Francesco Panara, Silvia Caporali, Stefania Urbani, Gianluca Veneziani, Sonia Esposto, Agnese Taticchi, Adolfo Rosati, Rosa Rao, Gaetano Perrotta, Maurizio Servili, Luciana Baldoni. Olive phenolic compounds: metabolic and transcriptional profiling during fruit development. BMC plant biology. 2012 Sep; 12(?):162. doi: 10.1186/1471-2229-12-162. [PMID: 22963618]
  • Carmen Romero-Segura, Carlos Sanz, Ana G Perez. Purification and characterization of an olive fruit beta-glucosidase involved in the biosynthesis of virgin olive oil phenolics. Journal of agricultural and food chemistry. 2009 Sep; 57(17):7983-8. doi: 10.1021/jf901293c. [PMID: 19689134]
  • A K Kiss, M Mańk, M F Melzig. Dual inhibition of metallopeptidases ACE and NEP by extracts, and iridoids from Ligustrum vulgare L. Journal of ethnopharmacology. 2008 Nov; 120(2):220-5. doi: 10.1016/j.jep.2008.08.015. [PMID: 18790039]
  • J J Ríos, M J Gil, F Gutiérrez-Rosales. Solid-phase extraction gas chromatography-ion trap-mass spectrometry qualitative method for evaluation of phenolic compounds in virgin olive oil and structural confirmation of oleuropein and ligstroside aglycons and their oxidation products. Journal of chromatography. A. 2005 Nov; 1093(1-2):167-76. doi: 10.1016/j.chroma.2005.07.033. [PMID: 16233882]
  • Ana María Gómez Caravaca, Alegría Carrasco Pancorbo, Beatriz Cañabate Díaz, Antonio Segura Carretero, Alberto Fernández Gutiérrez. Electrophoretic identification and quantitation of compounds in the polyphenolic fraction of extra-virgin olive oil. Electrophoresis. 2005 Sep; 26(18):3538-51. doi: 10.1002/elps.200500202. [PMID: 16167367]
  • Karina de la Torre-Carbot, Olga Jauregui, Eva Gimeno, Ana I Castellote, Rosa M Lamuela-Raventós, M Carmen López-Sabater. Characterization and quantification of phenolic compounds in olive oils by solid-phase extraction, HPLC-DAD, and HPLC-MS/MS. Journal of agricultural and food chemistry. 2005 Jun; 53(11):4331-40. doi: 10.1021/jf0501948. [PMID: 15913291]