Sanguiin H6 (BioDeep_00000402844)

natural product PANOMIX_OTCML-2023

代谢物信息卡片

7,8,9,12,13,14,28,29,30,33,34,35-dodecahydroxy-4,17,25,38-tetraoxo-3,18,21,24,39-pentaoxaheptacyclo[20.17.0.0^{2,19}.0^{5,10}.0^{11,16}.0^{26,31}.0^{32,37}]nonatriaconta-5(10),6,8,11(16),12,14,26(31),27,29,32(37),33,35-dodecaen-20-yl 3-({7,8,9,12,13,14,28,29,30,33,34,35-dodecahydroxy-4,17,25,38-tetraoxo-20-[(3,4,5-trihydroxyphenyl)carbonyloxy]-3,18,21,24,39-pentaoxaheptacyclo[20.17.0.0^{2,19}.0^{5,10}.0^{11,16}.0^{26,31}.0^{32,37}]nonatriaconta-5(10),6,8,11(16),12,14,26(31),27,29,32(37),33,35-dodecaen-36-yl}oxy)-4,5-dihydroxybenzoate

化学式: C82H54O52 (1870.1581084)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C2C(C3C(C(O2)OC(=O)C4=CC(=C(C(=C4)OC5=C(C(=C(C6=C5C(=O)OC7C(COC(=O)C8=CC(=C(C(=C86)O)O)O)OC(C9C7OC(=O)C2=CC(=C(C(=C2C2=C(C(=C(C=C2C(=O)O9)O)O)O)O)O)O)OC(=O)C2=CC(=C(C(=C2)O)O)O)O)O)O)O)O)OC(=O)C2=CC(=C(C(=C2C2=C(C(=C(C=C2C(=O)O3)O)O)O)O)O)O)OC(=O)C2=CC(=C(C(=C2C2=C(C(=C(C=C2C(=O)O1)O)O)O)O)O)O
InChI: InChI=1S/C82H54O52/c83-23-1-14(2-24(84)45(23)93)71(112)133-81-70-68(130-77(118)20-9-30(90)50(98)57(105)39(20)41-22(79(120)132-70)11-32(92)52(100)59(41)107)65-35(126-81)13-123-74(115)17-6-27(87)53(101)60(108)42(17)43-44(80(121)128-65)66(63(111)62(110)61(43)109)124-33-4-15(3-25(85)46(33)94)72(113)134-82-69-67(129-76(117)19-8-29(89)49(97)56(104)38(19)40-21(78(119)131-69)10-31(91)51(99)58(40)106)64-34(125-82)12-122-73(114)16-5-26(86)47(95)54(102)36(16)37-18(75(116)127-64)7-28(88)48(96)55(37)103/h1-11,34-35,64-65,67-70,81-111H,12-13H2

描述信息

同义名列表

4 个代谢物同义名

Sanguiin H6; 7,8,9,12,13,14,28,29,30,33,34,35-dodecahydroxy-4,17,25,38-tetraoxo-3,18,21,24,39-pentaoxaheptacyclo[20.17.0.0^{2,19}.0^{5,10}.0^{11,16}.0^{26,31}.0^{32,37}]nonatriaconta-5(10),6,8,11(16),12,14,26(31),27,29,32(37),33,35-dodecaen-20-yl 3-({7,8,9,12,13,14,28,29,30,33,34,35-dodecahydroxy-4,17,25,38-tetraoxo-20-[(3,4,5-trihydroxyphenyl)carbonyloxy]-3,18,21,24,39-pentaoxaheptacyclo[20.17.0.0^{2,19}.0^{5,10}.0^{11,16}.0^{26,31}.0^{32,37}]nonatriaconta-5(10),6,8,11(16),12,14,26(31),27,29,32(37),33,35-dodecaen-36-yl}oxy)-4,5-dihydroxybenzoate; Sanguiin H-6; Sanguiin H 6

数据库引用编号

6 个数据库交叉引用编号

ChEBI: CHEBI:192501
PubChem: 16181831
Metlin: METLIN86321
CAS: 82978-00-5
MoNA: PM008601
MoNA: PM012001

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

75062 - Rubus allegheniensis: 10.1248/CPB.41.1214
714495 - Rubus chingii: 10.1248/CPB.41.1214
1546416 - Rubus foliosus: 10.1016/0031-9422(92)83451-4
176136 - Rubus parvifolius: 10.1248/CPB.41.1214
75084 - Rubus pensilvanicus: 10.1248/CPB.41.1214
75085 - Rubus phoenicolasius: 10.1248/CPB.41.1214
321608 - Rubus pungens: 10.1016/0031-9422(92)83451-4
2823971 - Rubus sieboldii: 10.1248/CPB.41.1214
75097 - Rubus trilobus: 10.1016/0031-9422(92)83451-4
1546479 - Rubus vestitus: 10.1016/0031-9422(92)83451-4

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Eiko Sakai, Yuri Aoki, Masako Yoshimatsu, Kazuhisa Nishishita, Mayumi Iwatake, Yutaka Fukuma, Kuniaki Okamoto, Takashi Tanaka, Takayuki Tsukuba. Sanguiin H-6, a constituent of Rubus parvifolius L., inhibits receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis and bone resorption in vitro and prevents tumor necrosis factor-α-induced osteoclast formation in vivo. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2016 Jul; 23(8):828-37. doi: 10.1016/j.phymed.2016.04.002. [PMID: 27288918]
Mirosława Krauze-Baranowska, Daniel Głód, Marta Kula, Magdalena Majdan, Rafał Hałasa, Adam Matkowski, Weronika Kozłowska, Anna Kawiak. Chemical composition and biological activity of Rubus idaeus shoots--a traditional herbal remedy of Eastern Europe. BMC complementary and alternative medicine. 2014 Dec; 14(?):480. doi: 10.1186/1472-6882-14-480. [PMID: 25496130]
M Krauze-Baranowska, M Majdan, R Hałasa, D Głód, M Kula, I Fecka, A Orzeł. The antimicrobial activity of fruits from some cultivar varieties of Rubus idaeus and Rubus occidentalis. Food & function. 2014 Oct; 5(10):2536-41. doi: 10.1039/c4fo00129j. [PMID: 25131001]
Sung-Jin Lee, Hak-Kyo Lee. Sanguiin H-6 blocks endothelial cell growth through inhibition of VEGF binding to VEGF receptor. Archives of pharmacal research. 2005 Nov; 28(11):1270-4. doi: 10.1007/bf02978211. [PMID: 16350854]
Takako Yokozawa, Cui Ping Chen, Dong Young Rhyu, Takashi Tanaka, Jong Cheol Park, Kenichi Kitani. Potential of sanguiin H-6 against oxidative damage in renal mitochondria and apoptosis mediated by peroxynitrite in vivo. Nephron. 2002 Sep; 92(1):133-41. doi: 10.1159/000064483. [PMID: 12187096]
William Mullen, Jennifer McGinn, Michael E J Lean, Margaret R MacLean, Peter Gardner, Garry G Duthie, Takoa Yokota, Alan Crozier. Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties. Journal of agricultural and food chemistry. 2002 Aug; 50(18):5191-6. doi: 10.1021/jf020140n. [PMID: 12188628]