PRZ_M282 (BioDeep_00000402667)
代谢物信息卡片
N-(2-(2,4,6-Trichlorophenoxy)ethyl)propan-1-amine
化学式: C11H14Cl3NO (281.01409240000004)
中文名称: N-丙基-N-[2-(2,4,6-三氯苯氧基)乙基]胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCNCCOC1=C(C=C(C=C1Cl)Cl)Cl
InChI: InChI=1S/C11H14Cl3NO/c1-2-3-15-4-5-16-11-9(13)6-8(12)7-10(11)14/h6-7,15H,2-5H2,1H3
描述信息
CONFIDENCE Transformation product, tentative ID (Level 2b); INTERNAL_ID 2001
同义名列表
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Soebagijo Adi Soelistijo, Andi Makbul Aman, Hendra Zufry, Agung Pranoto, Achmad Rudijanto, Mohamed Hassanien. Indonesia DIA-RAMADAN Study: A Real-life, Prospective and Observational of Gliclazide MR in Type-2 Diabetes Patients During Ramadan Fasting.
Acta medica Indonesiana.
2022 Jan; 54(1):3-9. doi:
NULL. [PMID: 35398820] - Ewa Zurawska-Plaksej, Rafal Wiglusz, Agnieszka Piwowar, Katarzyna Wiglusz. In Vitro Investigation of Binding Interactions between Albumin-Gliclazide Model and Typical Hypotensive Drugs.
International journal of molecular sciences.
2021 Dec; 23(1):. doi:
10.3390/ijms23010286. [PMID: 35008711] - Syed Abbas Raza, Javed Akram, Azizul Hasan Aamir, Yakoob Ahmedani, Mohammad Imtiaz Hassan. Evaluation of the effectiveness and tolerability of gliclazide modified release 60 mg in patients with type 2 diabetes observing fasting during Ramadan in Pakistan: An analysis from the global DIA-RAMADAN study.
Diabetes research and clinical practice.
2021 Nov; 181(?):109086. doi:
10.1016/j.diabres.2021.109086. [PMID: 34634390] - M L Morieri, N Vitturi, A Avogaro, G Targher, G P Fadini. Prevalence of hepatic steatosis in patients with type 2 diabetes and response to glucose-lowering treatments. A multicenter retrospective study in Italian specialist care.
Journal of endocrinological investigation.
2021 Sep; 44(9):1879-1889. doi:
10.1007/s40618-021-01501-y. [PMID: 33432553] - Jeffry Adiwidjaja, Lucy Sasongko. Effect of Nigella sativa oil on pharmacokinetics and pharmacodynamics of gliclazide in rats.
Biopharmaceutics & drug disposition.
2021 Sep; 42(8):359-371. doi:
10.1002/bdd.2300. [PMID: 34327715] - Ruth L M Cordiner, Andrea Mari, Andrea Tura, Ewan R Pearson. The Impact of Low-dose Gliclazide on the Incretin Effect and Indices of Beta-cell Function.
The Journal of clinical endocrinology and metabolism.
2021 06; 106(7):2036-2046. doi:
10.1210/clinem/dgab151. [PMID: 33693776] - Fatemeh Taghizadeh, Seyed Jalal Hosseinimehr, Mehryar Zargari, Abbasali Karimpour Malekshah, Mansoureh Mirzaei, Fereshteh Talebpour Amiri. Alleviation of cisplatin-induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase-3 activity.
Pharmacology research & perspectives.
2021 05; 9(3):e00788. doi:
10.1002/prp2.788. [PMID: 34003600] - Shouq Alkhudhayri, Rania Sajini, Bashayer Alharbi, Jumana Qabbani, Yosra Al-Hindi, Arwa Fairaq, Amal Yousef. Investigating the beneficial effect of aliskiren in attenuating neuropathic pain in diabetic Sprague-Dawley rats.
Endocrinology, diabetes & metabolism.
2021 04; 4(2):e00209. doi:
10.1002/edm2.209. [PMID: 33855212] - Lucy Sasongko, Gladdis K Pratiwi, Margaretha Leo, Jeffry Adiwidjaja. Simultaneous HPLC Assay of Gliclazide and Ciprofloxacin in Plasma and its Implementation for Pharmacokinetic Study in Rats.
Journal of chromatographic science.
2021 Mar; 59(4):338-346. doi:
10.1093/chromsci/bmaa111. [PMID: 33401303] - Elliott L Rodriguez, Pingyang Tao, Ashley G Woolfork, Zhao Li, Ryan Matsuda, Zuchen Sun, David S Hage. Studies of binding by sulfonylureas with glyoxal- and methylglyoxal-modified albumin by immunoextraction using affinity microcolumns.
Journal of chromatography. A.
2021 Feb; 1638(?):461683. doi:
10.1016/j.chroma.2020.461683. [PMID: 33223150] - Mazhar Hussain, Asim Elahi, Abid Hussain, Javed Iqbal, Lubna Akhtar, Abdul Majid. Sodium-Glucose Cotransporter-2 (SGLT-2) Attenuates Serum Uric Acid (SUA) Level in Patients with Type 2 Diabetes.
Journal of diabetes research.
2021; 2021(?):9973862. doi:
10.1155/2021/9973862. [PMID: 34239940] - Sayed M M Mizar, Magy R Kozman, Ali A Abo-Saif, Basim A S Messiha. Combination of Captopril with Gliclazide Decreases Vascular and Renal Complications and Improves Glycemic Control in Rats with Streptozotocin- Induced Diabetes Mellitus.
Endocrine, metabolic & immune disorders drug targets.
2021; 21(6):1096-1106. doi:
10.2174/1871530320666200821160436. [PMID: 32955003] - Erik J M van Bommel, Frank Geurts, Marcel H A Muskiet, Adrian Post, Stephan J L Bakker, A H Jan Danser, Daan J Touw, Miranda van Berkel, Mark H H Kramer, Max Nieuwdorp, Ele Ferrannini, Jaap A Joles, Ewout J Hoorn, Daniël H van Raalte. SGLT2 inhibition versus sulfonylurea treatment effects on electrolyte and acid-base balance: secondary analysis of a clinical trial reaching glycemic equipoise: Tubular effects of SGLT2 inhibition in Type 2 diabetes.
Clinical science (London, England : 1979).
2020 12; 134(23):3107-3118. doi:
10.1042/cs20201274. [PMID: 33205810] - Ingrid Vasconcelos, Pedro Henrique Reis da Silva, Derick Rodrigues Davila Dias, Maria Betânia de Freitas Marques, Wagner da Nova Mussel, Tércio Assunção Pedrosa, Maria Elisa Scarpelli Ribeiro E Silva, Roberto Fernando de Souza Freitas, Ricardo Geraldo de Sousa, Christian Fernandes. Synthesis and characterization of a molecularly imprinted polymer (MIP) for solid-phase extraction of the antidiabetic gliclazide from human plasma.
Materials science & engineering. C, Materials for biological applications.
2020 Nov; 116(?):111191. doi:
10.1016/j.msec.2020.111191. [PMID: 32806298] - Prabhat Pratap Singh Tomar, Isaiah T Arkin. SARS-CoV-2 E protein is a potential ion channel that can be inhibited by Gliclazide and Memantine.
Biochemical and biophysical research communications.
2020 09; 530(1):10-14. doi:
10.1016/j.bbrc.2020.05.206. [PMID: 32828269] - Erik J M van Bommel, Mark M Smits, Danique Ruiter, Marcel H A Muskiet, Mark H H Kramer, Max Nieuwdorp, Daan J Touw, Hiddo J L Heerspink, Jaap A Joles, Daniël H van Raalte. Effects of dapagliflozin and gliclazide on the cardiorenal axis in people with type 2 diabetes.
Journal of hypertension.
2020 09; 38(9):1811-1819. doi:
10.1097/hjh.0000000000002480. [PMID: 32516291] - Fatemeh Taghizadeh, Seyed Jalal Hosseinimehr, Mehryar Zargari, Abbasali Karimpour Malekshah, Fereshteh Beigom Talebpour Amiri. Gliclazide attenuates cisplatin-induced nephrotoxicity through inhibiting NF-κB and caspase-3 activity.
IUBMB life.
2020 09; 72(9):2024-2033. doi:
10.1002/iub.2342. [PMID: 32687680] - Wen-Qiang Pan, Shu-Fan Wang, Bo-Ping Ding, Zhen-Gui Huang. [Protective effects of gliclazide on myocardium of diabetic rats and its mechanism].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.
2020 Sep; 36(5):402-407. doi:
10.12047/j.cjap.5999.2020.086. [PMID: 33629551] - Vidhushini Sekar, Sugumar Mani, R Malarvizhi, R Barathidasan, Hannah R Vasanthi. Positive interaction of mangiferin with selected oral hypoglycemic drugs: a therapeutic strategy to alleviate diabetic nephropathy in experimental rats.
Molecular biology reports.
2020 Jun; 47(6):4465-4475. doi:
10.1007/s11033-020-05517-0. [PMID: 32451927] - Mohamed Hassanein, Saud Al Sifri, Shehla Shaikh, Syed Abbas Raza, Javed Akram, Agung Pranoto, Achmad Rudijanto, Inass Shaltout, Md Fariduddin, Wan Mohd Izani Wan Mohamed, Fatheya Al Awadi, Thamer Alessa. A real-world study in patients with type 2 diabetes mellitus treated with gliclazide modified-release during fasting: DIA-RAMADAN.
Diabetes research and clinical practice.
2020 May; 163(?):108154. doi:
10.1016/j.diabres.2020.108154. [PMID: 32330510] - Noha F Abdelkader, Hebatollah E Eitah, Yousreya A Maklad, Amina A Gamaleldin, Manal A Badawi, Sanaa A Kenawy. New combination therapy of gliclazide and quercetin for protection against STZ-induced diabetic rats.
Life sciences.
2020 Apr; 247(?):117458. doi:
10.1016/j.lfs.2020.117458. [PMID: 32092333] - E J M van Bommel, H Herrema, M Davids, M H H Kramer, M Nieuwdorp, D H van Raalte. Effects of 12-week treatment with dapagliflozin and gliclazide on faecal microbiome: Results of a double-blind randomized trial in patients with type 2 diabetes.
Diabetes & metabolism.
2020 04; 46(2):164-168. doi:
10.1016/j.diabet.2019.11.005. [PMID: 31816432] - Meisam Saberi, Zahra Ramazani, Homeira Rashidi, Alihossein Saberi. The Effect of CYP2C9 Genotype Variants in Type 2 Diabetes on the Pharmacological Effectiveness of Sulfonylureas, Diabetic Retinopathy, and Nephropathy.
Vascular health and risk management.
2020; 16(?):241-248. doi:
10.2147/vhrm.s230639. [PMID: 32606720] - Erik J M van Bommel, Marcel H A Muskiet, Michaël J B van Baar, Lennart Tonneijck, Mark M Smits, Anna L Emanuel, Andrea Bozovic, A H Jan Danser, Frank Geurts, Ewout J Hoorn, Daan J Touw, Emil L Larsen, Henrik E Poulsen, Mark H H Kramer, Max Nieuwdorp, Jaap A Joles, Daniël H van Raalte. The renal hemodynamic effects of the SGLT2 inhibitor dapagliflozin are caused by post-glomerular vasodilatation rather than pre-glomerular vasoconstriction in metformin-treated patients with type 2 diabetes in the randomized, double-blind RED trial.
Kidney international.
2020 01; 97(1):202-212. doi:
10.1016/j.kint.2019.09.013. [PMID: 31791665] - Simon Mifsud, Emma Louise Schembri, Stephen Fava. A case of severe relapsing sulphonylurea-induced hypoglycaemia.
BMJ case reports.
2019 Dec; 12(12):. doi:
10.1136/bcr-2019-231368. [PMID: 31796456] - Anca Ungurianu, Oana Şeremet, Elvira Gagniuc, Octavian Tudor Olaru, Claudia Guţu, Daniela Grǎdinaru, Constantin Ionescu-Tȋrgovişte, Denisa Marginǎ, Rucsandra Dǎnciulescu-Miulescu. Preclinical and clinical results regarding the effects of a plant-based antidiabetic formulation versus well established antidiabetic molecules.
Pharmacological research.
2019 12; 150(?):104522. doi:
10.1016/j.phrs.2019.104522. [PMID: 31698065] - P-Y Yang, P-C Li, B Feng. Protective effects of gliclazide on high glucose and AGEs-induced damage of glomerular mesangial cells and renal tubular epithelial cells via inhibiting RAGE-p22phox-NF-kB pathway.
European review for medical and pharmacological sciences.
2019 Oct; 23(20):9099-9107. doi:
10.26355/eurrev_201910_19313. [PMID: 31696501] - Chunmei Zhang, Piyong Ma, Zhongyan Zhao, Nan Jiang, Dede Lian, Pengfei Huo, Hailing Yang. miRNA‑mRNA regulatory network analysis of mesenchymal stem cell treatment in cisplatin‑induced acute kidney injury identifies roles for miR‑210/Serpine1 and miR‑378/Fos in regulating inflammation.
Molecular medicine reports.
2019 Aug; 20(2):1509-1522. doi:
10.3892/mmr.2019.10383. [PMID: 31257474] - Vidhushini Sekar, Sugumar Mani, R Malarvizhi, P Nithya, Hannah R Vasanthi. Antidiabetic effect of mangiferin in combination with oral hypoglycemic agents metformin and gliclazide.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Jun; 59(?):152901. doi:
10.1016/j.phymed.2019.152901. [PMID: 30981189] - Wen-Huan Feng, Yan Bi, Ping Li, Ting-Ting Yin, Cai-Xia Gao, Shan-Mei Shen, Li-Jun Gao, Dong-Hui Yang, Da-Long Zhu. Effects of liraglutide, metformin and gliclazide on body composition in patients with both type 2 diabetes and non-alcoholic fatty liver disease: A randomized trial.
Journal of diabetes investigation.
2019 Mar; 10(2):399-407. doi:
10.1111/jdi.12888. [PMID: 29957886] - Diana Ioana Pop, Monica Oroian, Sandeep Bhardwaj, Adriana Marcovici, Arshad Khuroo, Ravi Kochhar, Laurian Vlase. Bioequivalence of Two Formulations of Gliclazide in a Randomized Crossover Study in Healthy Caucasian Subjects Under Fasting Conditions.
Clinical pharmacology in drug development.
2019 01; 8(1):16-21. doi:
10.1002/cpdd.445. [PMID: 29578647] - Agnieszka Szkudlarek, Jadwiga Pożycka, Małgorzata Maciążek-Jurczyk. Influence of Piracetam on Gliclazide-Glycated Human Serum Albumin Interaction. A Spectrofluorometric Study.
Molecules (Basel, Switzerland).
2018 Dec; 24(1):. doi:
10.3390/molecules24010111. [PMID: 30597970] - Ying-Wen Zhang, Xiuping Wang, Xiaodan Ren, Manling Zhang. Involvement of glucose-regulated protein 78 and spliced X-box binding protein 1 in the protective effect of gliclazide in diabetic nephropathy.
Diabetes research and clinical practice.
2018 Dec; 146(?):41-47. doi:
10.1016/j.diabres.2017.04.019. [PMID: 28951332] - Andrzej Czyrski, Matylda Resztak, Tadeusz Hermann. Determination of gliclazide minimum concentration in type 2 diabetes mellitus patients.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Oct; 106(?):1267-1270. doi:
10.1016/j.biopha.2018.07.078. [PMID: 30119196] - Rui Zhang, Xiaojun Zhou, Xue Shen, Tianyue Xie, Chunmei Xu, Zhiwei Zou, Jianjun Dong, Lin Liao. Different sulfonylureas induce the apoptosis of proximal tubular epithelial cell differently via closing KATP channel.
Molecular medicine (Cambridge, Mass.).
2018 09; 24(1):47. doi:
10.1186/s10020-018-0042-5. [PMID: 30180807] - Yang Zhou, Cheng Hu, Xinjie Zhao, Ping Luo, Jingyi Lu, Qing Li, Miao Chen, Dandan Yan, Xin Lu, Hongwei Kong, Weiping Jia, Guowang Xu. Serum Metabolomics Study of Gliclazide-Modified-Release-Treated Type 2 Diabetes Mellitus Patients Using a Gas Chromatography-Mass Spectrometry Method.
Journal of proteome research.
2018 04; 17(4):1575-1585. doi:
10.1021/acs.jproteome.7b00866. [PMID: 29460634] - Sigrid C van Steen, Mark Woodward, John Chalmers, Qiang Li, Michel Marre, Mark E Cooper, Pavel Hamet, Giuseppe Mancia, Stephen Colagiuri, Bryan Williams, Diederick E Grobbee, J Hans DeVries. Haemoglobin glycation index and risk for diabetes-related complications in the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial.
Diabetologia.
2018 04; 61(4):780-789. doi:
10.1007/s00125-017-4539-1. [PMID: 29308539] - Ewa Żurawska-Płaksej, Anna Rorbach-Dolata, Katarzyna Wiglusz, Agnieszka Piwowar. The effect of glycation on bovine serum albumin conformation and ligand binding properties with regard to gliclazide.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2018 Jan; 189(?):625-633. doi:
10.1016/j.saa.2017.08.071. [PMID: 28888191] - Shuo Lin, Mu Chen, Wanling Chen, Keyi Lin, Panwei Mu, Bilian Zhu, Wen Xu, Manman Wang, Jianping Weng, Longyi Zeng. A Randomized Trial of Insulin Glargine plus Oral Hypoglycemic Agents versus Continuous Subcutaneous Insulin Infusion to Treat Newly Diagnosed Type 2 Diabetes.
Journal of diabetes research.
2018; 2018(?):2791584. doi:
10.1155/2018/2791584. [PMID: 30420969] - Peter Proks, Holger Kramer, Elizabeth Haythorne, Frances M Ashcroft. Binding of sulphonylureas to plasma proteins - A KATP channel perspective.
PloS one.
2018; 13(5):e0197634. doi:
10.1371/journal.pone.0197634. [PMID: 29772022] - Svetlana Golocorbin-Kon, Jelena Calasan, Boris Milijasevic, Sasa Vukmirovic, Mladena Lalic-Popovic, Momir Mikov, Hani Al-Salami. High-Loading Dose of Microencapsulated Gliclazide Formulation Exerted a Hypoglycaemic Effect on Type 1 Diabetic Rats and Incorporation of a Primary Deconjugated Bile Acid, Diminished the Hypoglycaemic Antidiabetic Effect.
European journal of drug metabolism and pharmacokinetics.
2017 Dec; 42(6):1005-1011. doi:
10.1007/s13318-017-0415-0. [PMID: 28547295] - Miroslava Kameníková, Paul Georg Furtmüller, Mária Klacsová, Arturo Lopez-Guzman, José Luis Toca-Herrera, Anika Vitkovská, Ferdinand Devínsky, Pavel Mučaji, Milan Nagy. Influence of quercetin on the interaction of gliclazide with human serum albumin - spectroscopic and docking approaches.
Luminescence : the journal of biological and chemical luminescence.
2017 Nov; 32(7):1203-1211. doi:
10.1002/bio.3312. [PMID: 28513070] - Jaya Sujatha Gopal-Kothandapani, Katherine P Wright, Sivagamy Sithambaram, Anuja Natarajan. Dilemma of diagnosing sulphonylurea overdose in children: deliberations and considerations before reaching a diagnosis.
BMJ case reports.
2017 Aug; 2017(?):. doi:
10.1136/bcr-2017-220044. [PMID: 28847991] - Ismail A Raslan, Emily G McDonald, Todd C Lee. Missed Opportunities for Deprescription: A Teachable Moment.
JAMA internal medicine.
2017 07; 177(7):1028-1029. doi:
10.1001/jamainternmed.2017.1435. [PMID: 28475657] - Sanjay Kalra, Ashok Kumar Das. Epidemiologic Surveillance of Glycemic Response to a Scored, Breakable, Extended Release, Fixed Dose Combination of Gliclazide and Metformin in Persons with Type 2 Diabetes.
The Journal of the Association of Physicians of India.
2017 Jun; 65(6):38-41. doi:
NULL. [PMID: 28782312] - Dalia M Abd El Motteleb, Dalia I Abd El Aleem. Renoprotective effect of Hypericum perforatum against diabetic nephropathy in rats: Insights in the underlying mechanisms.
Clinical and experimental pharmacology & physiology.
2017 Apr; 44(4):509-521. doi:
10.1111/1440-1681.12729. [PMID: 28079268] - Lijie Wang, Xinggang Yang, Yan Di, Kai Chen, Haoyang Wen, Weisan Pan. Zero-Order Controlled Delivery of Gliclazide from Polyethylene Oxides Matrix Tables: In vitro and In vivo Evaluation.
Current drug delivery.
2017; 14(1):136-144. doi:
10.2174/1567201813666160322143248. [PMID: 27000027] - S G Butaeva, A S Ametov, A V Bugrov, V V Dolgov. [Glycemic variability and oxidative stress in patients with type 2 diabetes mellitus during combined glucose-lowering therapy].
Terapevticheskii arkhiv.
2017 ; 89(10):36-39. doi:
10.17116/terarkh2017891036-39. [PMID: 29171468] - Amal M Mahfoz, Hekma A Abd El-Latif, Lamiaa A Ahmed, Nahed M Hassanein, Afaf A Shoka. Anti-diabetic and renoprotective effects of aliskiren in streptozotocin-induced diabetic nephropathy in female rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2016 Dec; 389(12):1315-1324. doi:
10.1007/s00210-016-1299-2. [PMID: 27612855] - Kamel Mohammedi, Mark Woodward, Sophia Zoungas, Qiang Li, Stephen Harrap, Anushka Patel, Michel Marre, John Chalmers. Absence of Peripheral Pulses and Risk of Major Vascular Outcomes in Patients With Type 2 Diabetes.
Diabetes care.
2016 Dec; 39(12):2270-2277. doi:
10.2337/dc16-1594. [PMID: 27679583] - Sangeetha Mathavan, Nigel Chen-Tan, Frank Arfuso, Hani Al-Salami. A comprehensive study of novel microcapsules incorporating gliclazide and a permeation enhancing bile acid: hypoglycemic effect in an animal model of Type-1 diabetes.
Drug delivery.
2016 Oct; 23(8):2869-2880. doi:
10.3109/10717544.2015.1110846. [PMID: 26610261] - E Oei, N Samad, A Visser, T A Chowdhury, S L Fan. Use of continuous glucose monitoring in patients with diabetes on peritoneal dialysis: poor correlation with HbA1c and high incidence of hypoglycaemia.
Diabetic medicine : a journal of the British Diabetic Association.
2016 09; 33(9):e17-20. doi:
10.1111/dme.12988. [PMID: 26470840] - Wotan Zeng, Yali Guo, Peixian Chen, Zhike Liu, Dafang Chen, Chunji Han. CYP2C93 variant is associated with antidiabetes efficacy of gliclazide in Chinese type 2 diabetes patients.
Journal of diabetes investigation.
2016 Sep; 7(5):764-8. doi:
10.1111/jdi.12486. [PMID: 27181593] - Qiu-Ju Zhang, Bao-Sheng Liu, Gai-Xia Li, Rong Han. Using resonance light scattering and UV/vis absorption spectroscopy to study the interaction between gliclazide and bovine serum albumin.
Luminescence : the journal of biological and chemical luminescence.
2016 Aug; 31(5):1109-14. doi:
10.1002/bio.3079. [PMID: 26663583] - Muh Geot Wong, Vlado Perkovic, John Chalmers, Mark Woodward, Qiang Li, Mark E Cooper, Pavel Hamet, Stephen Harrap, Simon Heller, Stephen MacMahon, Giuseppe Mancia, Michel Marre, David Matthews, Bruce Neal, Neil Poulter, Anthony Rodgers, Bryan Williams, Sophia Zoungas. Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON.
Diabetes care.
2016 May; 39(5):694-700. doi:
10.2337/dc15-2322. [PMID: 27006512] - Onur Akın, Ediz Yeşilkaya, Erkan Sari, Çağdaş Akar, Gökalp Başbozkurt, Enis Macit, Ibrahim Aydin, Abdullah Taşlipinar, Hüsamettin Gül. A Rare Reason of Hyperinsulinism: Munchausen Syndrome by Proxy.
Hormone research in paediatrics.
2016; 86(6):416-419. doi:
10.1159/000446497. [PMID: 27221098] - Xiu Feng, Lu Yuan, Yun Hu, Yunqing Zhu, Fan Yang, Lanlan Jiang, Rengna Yan, Yong Luo, Enhui Zhao, Chenxiao Liu, Ying Wang, Qi Li, Xin Cao, Qian Li, Jianhua Ma. Gliclazide-Induced Insulin Autoimmune Syndrome: A Rare Case Report and Review on Literature.
Endocrine, metabolic & immune disorders drug targets.
2016; 16(4):230-234. doi:
10.2174/1871530316666161223144558. [PMID: 28017142] - V Mohan, V Chopra, D Sanyal, S Jain, J Jayaprakashsai. Treatment of Type 2 Diabetes with a Breakable Extended Release Gliclazide Formulation in Primary Care: The Xrise Study.
The Journal of the Association of Physicians of India.
2015 Dec; 63(12):26-29. doi:
NULL. [PMID: 27666900] - Ryan Matsuda, Donald Jobe, Jared Beyersdorf, David S Hage. Analysis of drug-protein binding using on-line immunoextraction and high-performance affinity microcolumns: Studies with normal and glycated human serum albumin.
Journal of chromatography. A.
2015 Oct; 1416(?):112-20. doi:
10.1016/j.chroma.2015.09.023. [PMID: 26381571] - Jian Zhou, Fenping Zheng, Xiaohui Guo, Huazhang Yang, Muxun Zhang, Haoming Tian, Lixin Guo, Qiang Li, Yifei Mo, Weiping Jia. Glargine insulin/gliclazide MR combination therapy is more effective than premixed insulin monotherapy in Chinese patients with type 2 diabetes inadequately controlled on oral antidiabetic drugs.
Diabetes/metabolism research and reviews.
2015 Oct; 31(7):725-33. doi:
10.1002/dmrr.2661. [PMID: 25952634] - Memy Hegazy Hassan, Gamil Mohamed Abd-Allah. Effects of metformin plus gliclazide versus metformin plus glimepiride on cardiovascular risk factors in patients with type 2 diabetes mellitus.
Pakistan journal of pharmaceutical sciences.
2015 Sep; 28(5):1723-30. doi:
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Diabetes & metabolism.
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European journal of drug metabolism and pharmacokinetics.
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Behavioural pharmacology.
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General physiology and biophysics.
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Arquivos brasileiros de endocrinologia e metabologia.
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