Denatonium (BioDeep_00000402605)
代谢物信息卡片
化学式: [C21H29N2O]+ (325.228)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC[N+](CC)(CC(=O)NC1=C(C)C=CC=C1C)CC1=CC=CC=C1
InChI: InChI=1S/C21H28N2O/c1-5-23(6-2,15-19-13-8-7-9-14-19)16-20(24)22-21-17(3)11-10-12-18(21)4/h7-14H,5-6,15-16H2,1-4H3/p+1
描述信息
D002491 - Central Nervous System Agents > D000075162 - Abuse-Deterrent Formulations
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D010592 - Pharmaceutic Aids > D000075528 - Aversive Agents
CONFIDENCE standard compound; INTERNAL_ID 2876
INTERNAL_ID 2876; CONFIDENCE standard compound
CONFIDENCE Reference Standard (Level 1)
同义名列表
1 个代谢物同义名
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:95255
- PubChem: 15488
- ChEMBL: CHEMBL1738972
- CAS: 47324-98-1
- MoNA: AU287606
- MoNA: AU287605
- MoNA: AU287604
- MoNA: AU287603
- MoNA: AU287602
- MoNA: AU287601
- MoNA: TUE00283
- MoNA: TUE00282
- MoNA: TUE00281
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Jorge A García-Valenzuela, Martha R Baez-Gaxiola. Comments on the Risks From Exposure to Denatonium Benzoate (Bitrex®): Denatured Alcohol Disinfection and Pandemic Times.
International journal of toxicology.
2021 10; 40(5):475-477. doi:
10.1177/10915818211038498. [PMID: 34337977] - Sisi Liu, Shibao Chen, Xiaohao Li, Yubo Yue, Jinling Li, Paul N Williams, Zhanyun Wang, Cailin Li, Yuanyuan Yang, Guang-Guo Ying, Chang-Er Chen. Development and application of diffusive gradients in thin-films for in situ sampling of the bitterest chemical - denatonium benzoate in waters.
Journal of hazardous materials.
2021 09; 418(?):126393. doi:
10.1016/j.jhazmat.2021.126393. [PMID: 34329009] - Wout Verbeure, Eveline Deloose, Joran Tóth, Jens F Rehfeld, Lukas Van Oudenhove, Inge Depoortere, Jan Tack. The endocrine effects of bitter tastant administration in the gastrointestinal system: intragastric versus intraduodenal administration.
American journal of physiology. Endocrinology and metabolism.
2021 07; 321(1):E1-E10. doi:
10.1152/ajpendo.00636.2020. [PMID: 34029163] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Alireza Jahan-Mihan, Bohdan L Luhovyy, Dalia El Khoury, G Harvey Anderson. Dietary proteins as determinants of metabolic and physiologic functions of the gastrointestinal tract.
Nutrients.
2011 05; 3(5):574-603. doi:
10.3390/nu3050574. [PMID: 22254112] - Deepak A Deshpande, Wayne C H Wang, Elizabeth L McIlmoyle, Kathryn S Robinett, Rachel M Schillinger, Steven S An, James S K Sham, Stephen B Liggett. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction.
Nature medicine.
2010 Nov; 16(11):1299-304. doi:
10.1038/nm.2237. [PMID: 20972434] - Bronwen Martin, Yu-Kyong Shin, Caitlin M White, Sunggoan Ji, Wook Kim, Olga D Carlson, Joshua K Napora, Wayne Chadwick, Megan Chapter, James A Waschek, Mark P Mattson, Stuart Maudsley, Josephine M Egan. Vasoactive intestinal peptide-null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud leptin receptor expression.
Diabetes.
2010 May; 59(5):1143-52. doi:
10.2337/db09-0807. [PMID: 20150284] - . Final report of the safety assessment of Alcohol Denat., including SD Alcohol 3-A, SD Alcohol 30, SD Alcohol 39, SD Alcohol 39-B, SD Alcohol 39-C, SD Alcohol 40, SD Alcohol 40-B, and SD Alcohol 40-C, and the denaturants, Quassin, Brucine Sulfate/Brucine, and Denatonium Benzoate.
International journal of toxicology.
2008; 27 Suppl 1(?):1-43. doi:
10.1080/10915810802032388. [PMID: 18569160] - Kenji Maehashi, Mami Matano, Miho Nonaka, Shigezo Udaka, Yasushi Yamamoto. Riboflavin-binding protein is a novel bitter inhibitor.
Chemical senses.
2008 Jan; 33(1):57-63. doi:
10.1093/chemse/bjm062. [PMID: 17846099] - Ryan M Carnahan, Eric C Kutscher, Marilee D Obritsch, Larry D Rasmussen. Acute ethanol intoxication after consumption of hairspray.
Pharmacotherapy.
2005 Nov; 25(11):1646-50. doi:
10.1592/phco.2005.25.11.1646. [PMID: 16232026] - T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
1975 Jul; 71(5):457-62. doi:
. [PMID: 280]
