Antimycin A (BioDeep_00000400136)
Main id: BioDeep_00000003606
natural product Toxin Volatile Flavor Compounds
代谢物信息卡片
化学式: C28H40N2O9 (548.273367)
中文名称: 抗霉素A1, 抗霉素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CC(C)C
InChI: InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison.
同义名列表
3 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:22584
- ChEBI: CHEBI:2762
- KEGG: C11339
- PubChem: 14957
- ChEMBL: CHEMBL211501
- MeSH: Antimycin A
- CAS: 116095-18-2
- CAS: 1397-94-0
- CAS: 642-15-9
- MoNA: CCMSLIB00000578442
- MetaboLights: MTBLC22584
- PubChem: 13514
- NIKKAJI: J7.054H
- KNApSAcK: 2762
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Dario Leister, Giada Marino, Jun Minagawa, Marcel Dann. An ancient function of PGR5 in iron delivery?.
Trends in plant science.
2022 10; 27(10):971-980. doi:
10.1016/j.tplants.2022.04.006
. [PMID: 35618596] - Felix Buchert, Martin Scholz, Michael Hippler. Electron transfer via cytochrome b6f complex displays sensitivity to antimycin A upon STT7 kinase activation.
The Biochemical journal.
2022 01; 479(1):111-127. doi:
10.1042/bcj20210802
. [PMID: 34981811] - Thilo Rühle, Marcel Dann, Bennet Reiter, Danja Schünemann, Belen Naranjo, Jan-Ferdinand Penzler, Tatjana Kleine, Dario Leister. PGRL2 triggers degradation of PGR5 in the absence of PGRL1.
Nature communications.
2021 06; 12(1):3941. doi:
10.1038/s41467-021-24107-7
. [PMID: 34168134] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040
. [PMID: 33910017] - Seán M Kilbride, Jayne E Telford, Gavin P Davey. Complex I Controls Mitochondrial and Plasma Membrane Potentials in Nerve Terminals.
Neurochemical research.
2021 Jan; 46(1):100-107. doi:
10.1007/s11064-020-02990-8
. [PMID: 32130629] - Tzu-Jung Yu, Che-Yu Hsieh, Jen-Yang Tang, Li-Ching Lin, Hurng-Wern Huang, Hui-Ru Wang, Yun-Chiao Yeh, Ya-Ting Chuang, Fu Ou-Yang, Hsueh-Wei Chang. Antimycin A shows selective antiproliferation to oral cancer cells by oxidative stress-mediated apoptosis and DNA damage.
Environmental toxicology.
2020 Nov; 35(11):1212-1224. doi:
10.1002/tox.22986
. [PMID: 32662599] - Natalia Gazizova, Daniya Rakhmatullina, Farida Minibayeva. Effect of respiratory inhibitors on mitochondrial complexes and ADP/ATP translocators in the Triticum aestivum roots.
Plant physiology and biochemistry : PPB.
2020 Jun; 151(?):601-607. doi:
10.1016/j.plaphy.2020.04.014
. [PMID: 32335383] - Shuna Cui, Minghui Li, Rabeay Y A Hassan, Anna Heintz-Buschart, Junsong Wang, Ursula Bilitewski. Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages.
mSphere.
2020 04; 5(2):. doi:
10.1128/msphere.00016-20
. [PMID: 32295866] - Amy Keller, Sara E Hull, Hanan Elajaili, Aspen Johnston, Leslie A Knaub, Ji Hye Chun, Lori Walker, Eva Nozik-Grayck, Jane E B Reusch. (-)-Epicatechin Modulates Mitochondrial Redox in Vascular Cell Models of Oxidative Stress.
Oxidative medicine and cellular longevity.
2020; 2020(?):6392629. doi:
10.1155/2020/6392629
. [PMID: 32587663] - Julius Ver Sagun, Murray R Badger, Wah Soon Chow, Oula Ghannoum. Cyclic electron flow and light partitioning between the two photosystems in leaves of plants with different functional types.
Photosynthesis research.
2019 Dec; 142(3):321-334. doi:
10.1007/s11120-019-00666-1
. [PMID: 31520186] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Meng-Meng Zhang, Da-Yong Fan, Keach Murakami, Murray R Badger, Guang-Yu Sun, Wah Soon Chow. Partially Dissecting Electron Fluxes in Both Photosystems in Spinach Leaf Disks during Photosynthetic Induction.
Plant & cell physiology.
2019 Oct; 60(10):2206-2219. doi:
10.1093/pcp/pcz114
. [PMID: 31271439] - Nicole A Alber, Greg C Vanlerberghe. Signaling interactions between mitochondria and chloroplasts in Nicotiana tabacum leaf.
Physiologia plantarum.
2019 Oct; 167(2):188-204. doi:
10.1111/ppl.12879
. [PMID: 30467859] - Veronika Zelinová, Loriana Demecsová, Ladislav Tamás. Impact of antimycin A and myxothiazol on cadmium-induced superoxide, hydrogen peroxide, and nitric oxide generation in barley root tip.
Protoplasma.
2019 Sep; 256(5):1375-1383. doi:
10.1007/s00709-019-01389-9
. [PMID: 31079230] - Julie Mondet, Caroline Lo Presti, Catherine Garrel, Kristina Skaare, Clara Mariette, Sylvain Carras, Sophie Park, Martin Carré, Claude-Eric Bulabois, Lysiane Molina, Rémy Gressin, Anne Thiebaut, Stéphane Courby, Nuria Socoro-Yuste, Patrice Faure, Anne Mc Leer-Florin, Jean-Yves Cahn, Pascal Mossuz. Adult patients with de novo acute myeloid leukemia show a functional deregulation of redox balance at diagnosis which is correlated with molecular subtypes and overall survival.
Haematologica.
2019 09; 104(9):e393-e397. doi:
10.3324/haematol.2018.206821
. [PMID: 30819920] - Hu Wang, Fanny Cheung, Anna C Stoll, Patricia Rockwell, Maria E Figueiredo-Pereira. Mitochondrial and calcium perturbations in rat CNS neurons induce calpain-cleavage of Parkin: Phosphatase inhibition stabilizes pSer65Parkin reducing its calpain-cleavage.
Biochimica et biophysica acta. Molecular basis of disease.
2019 06; 1865(6):1436-1450. doi:
10.1016/j.bbadis.2019.02.016
. [PMID: 30796971] - Alexander A Bulychev, Anna A Rybina. Long-range interactions of Chara chloroplasts are sensitive to plasma-membrane H+ flows and comprise separate photo- and dark-operated pathways.
Protoplasma.
2018 Nov; 255(6):1621-1634. doi:
10.1007/s00709-018-1255-8
. [PMID: 29704048] - Rodrigo Gómez, Néstor Carrillo, María P Morelli, Suresh Tula, Fahimeh Shahinnia, Mohammad-Reza Hajirezaei, Anabella F Lodeyro. Faster photosynthetic induction in tobacco by expressing cyanobacterial flavodiiron proteins in chloroplasts.
Photosynthesis research.
2018 May; 136(2):129-138. doi:
10.1007/s11120-017-0449-9
. [PMID: 29022124] - Olga Rafikova, Anup Srivastava, Ankit A Desai, Ruslan Rafikov, Stevan P Tofovic. Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung.
Respiratory research.
2018 04; 19(1):69. doi:
10.1186/s12931-018-0776-1
. [PMID: 29685148] - Aaron Pitre, Yubin Ge, Wenwei Lin, Yao Wang, Yu Fukuda, Jamshid Temirov, Aaron H Phillips, Jennifer L Peters, Yiping Fan, Jing Ma, Amanda Nourse, Chandrima Sinha, Hai Lin, Richard Kriwacki, James R Downing, Tanja A Gruber, Victoria E Centonze, Anjaparavanda P Naren, Taosheng Chen, John D Schuetz. An unexpected protein interaction promotes drug resistance in leukemia.
Nature communications.
2017 11; 8(1):1547. doi:
10.1038/s41467-017-01678-y
. [PMID: 29146910] - Barbara Karpinska, Sarah Owdah Alomrani, Christine H Foyer. Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
2017 Sep; 372(1730):. doi:
10.1098/rstb.2016.0392
. [PMID: 28808105] - Fan Wang, Shu-Na Fu, Yi-Xuan Bao, Yu Yang, Hui-Fang Shen, Bi-Run Lin, Guang-Xiong Zhou. Kitamycin C, a new antimycin-type antibiotic from Streptomyces antibioticus strain 200-09.
Natural product research.
2017 Aug; 31(15):1819-1824. doi:
10.1080/14786419.2017.1295240
. [PMID: 28278640] - Jialun Luo, Yiming Tao, Xinling Liang, Yuanhan Chen, Li Zhang, Fen Jiang, Shuangxin Liu, Zhiming Ye, Zhilian Li, Wei Shi. Flow control effect of necrostatin-1 on cell death of the NRK-52E renal tubular epithelial cell line.
Molecular medicine reports.
2017 Jul; 16(1):57-62. doi:
10.3892/mmr.2017.6556
. [PMID: 28487950] - Nicole A Alber, Hampavi Sivanesan, Greg C Vanlerberghe. The occurrence and control of nitric oxide generation by the plant mitochondrial electron transport chain.
Plant, cell & environment.
2017 Jul; 40(7):1074-1085. doi:
10.1111/pce.12884
. [PMID: 27987212] - Xinhua Zhang, Aneta Ivanova, Klaas Vandepoele, Jordan Radomiljac, Jan Van de Velde, Oliver Berkowitz, Patrick Willems, Yue Xu, Sophia Ng, Olivier Van Aken, Owen Duncan, Botao Zhang, Veronique Storme, Kai Xun Chan, Dries Vaneechoutte, Barry James Pogson, Frank Van Breusegem, James Whelan, Inge De Clercq. The Transcription Factor MYB29 Is a Regulator of ALTERNATIVE OXIDASE1a.
Plant physiology.
2017 03; 173(3):1824-1843. doi:
10.1104/pp.16.01494
. [PMID: 28167700] - Esther Peters, Tom Schirris, Alexander H van Asbeck, Jelle Gerretsen, Jennifer Eymael, Angel Ashikov, Merel J W Adjobo-Hermans, Frans Russel, Peter Pickkers, Rosalinde Masereeuw. Effects of a human recombinant alkaline phosphatase during impaired mitochondrial function in human renal proximal tubule epithelial cells.
European journal of pharmacology.
2017 Feb; 796(?):149-157. doi:
10.1016/j.ejphar.2016.12.034
. [PMID: 28012971] - Takahiro Sakai, Jun Imai, Tomohiro Ito, Hidetsugu Takagaki, Michio Ui, Shinichi Hatta. The novel antioxidant TA293 reveals the role of cytoplasmic hydroxyl radicals in oxidative stress-induced senescence and inflammation.
Biochemical and biophysical research communications.
2017 Jan; 482(4):1183-1189. doi:
10.1016/j.bbrc.2016.12.009
. [PMID: 27923656] - Kazuya Hagiwara, Masae Okura, Yasuyuki Sumikawa, Tokimasa Hida, Atsushi Kuno, Yoshiyuki Horio, Toshiharu Yamashita. Biochemical effects of the flavanol-rich lychee fruit extract on the melanin biosynthesis and reactive oxygen species.
The Journal of dermatology.
2016 Oct; 43(10):1174-1183. doi:
10.1111/1346-8138.13326
. [PMID: 26970333] - Richard A Zager, Ali C M Johnson, Kirsten Frostad. An evaluation of the antioxidant protein α1-microglobulin as a renal tubular cytoprotectant.
American journal of physiology. Renal physiology.
2016 09; 311(3):F640-51. doi:
10.1152/ajprenal.00264.2016
. [PMID: 27170684] - Mathias Labs, Thilo Rühle, Dario Leister. The antimycin A-sensitive pathway of cyclic electron flow: from 1963 to 2015.
Photosynthesis research.
2016 Sep; 129(3):231-8. doi:
10.1007/s11120-016-0217-2
. [PMID: 26781235] - Daniya Rakhmatullina, Anastasiya Ponomareva, Natalia Gazizova, Farida Minibayeva. Mitochondrial morphology and dynamics in Triticum aestivum roots in response to rotenone and antimycin A.
Protoplasma.
2016 Sep; 253(5):1299-308. doi:
10.1007/s00709-015-0888-0
. [PMID: 26411562] - Da-Yong Fan, Duncan Fitzpatrick, Riichi Oguchi, Weimin Ma, Jiancun Kou, Wah Soon Chow. Obstacles in the quantification of the cyclic electron flux around Photosystem I in leaves of C3 plants.
Photosynthesis research.
2016 Sep; 129(3):239-51. doi:
10.1007/s11120-016-0223-4
. [PMID: 26846653] - Venkata Suresh Vajrala, Emmanuel Suraniti, Michel Rigoulet, Anne Devin, Neso Sojic, Stéphane Arbault. PDMS microwells for multi-parametric monitoring of single mitochondria on a large scale: a study of their individual membrane potential and endogenous NADH.
Integrative biology : quantitative biosciences from nano to macro.
2016 08; 8(8):836-43. doi:
10.1039/c6ib00064a
. [PMID: 27384613] - Luca Bellini, Marta Vadori, Giulia Maria De Benedictis, Roberto Busetto. Effects of opioids on proximal renal tubular cells undergoing ATP depletion.
Journal of pharmacological sciences.
2016 Aug; 131(4):288-91. doi:
10.1016/j.jphs.2016.08.002
. [PMID: 27569459] - Riyad El-Khoury, Eveliina Kaulio, Katariina A Lassila, Damian C Crowther, Howard T Jacobs, Pierre Rustin. Expression of the alternative oxidase mitigates beta-amyloid production and toxicity in model systems.
Free radical biology & medicine.
2016 07; 96(?):57-66. doi:
10.1016/j.freeradbiomed.2016.04.006
. [PMID: 27094492] - Chihiro K A Watanabe, Wataru Yamori, Shunichi Takahashi, Ichiro Terashima, Ko Noguchi. Mitochondrial Alternative Pathway-Associated Photoprotection of Photosystem II is Related to the Photorespiratory Pathway.
Plant & cell physiology.
2016 Jul; 57(7):1426-1431. doi:
10.1093/pcp/pcw036
. [PMID: 26903530] - Olivier Van Aken, Inge De Clercq, Aneta Ivanova, Simon R Law, Frank Van Breusegem, A Harvey Millar, James Whelan. Mitochondrial and Chloroplast Stress Responses Are Modulated in Distinct Touch and Chemical Inhibition Phases.
Plant physiology.
2016 07; 171(3):2150-65. doi:
10.1104/pp.16.00273
. [PMID: 27208304] - Elena B Averina, Dmitry A Vasilenko, Yulia A Gracheva, Yuri K Grishin, Eugene V Radchenko, Vladimir V Burmistrov, Gennady M Butov, Margarita E Neganova, Tatyana P Serkova, Olga M Redkozubova, Elena F Shevtsova, Elena R Milaeva, Tamara S Kuznetsova, Nikolay S Zefirov. Synthesis and biological evaluation of novel 5-hydroxylaminoisoxazole derivatives as lipoxygenase inhibitors and metabolism enhancing agents.
Bioorganic & medicinal chemistry.
2016 Feb; 24(4):712-20. doi:
10.1016/j.bmc.2015.12.040
. [PMID: 26753816] - Stiina Rasimus-Sahari, Raimo Mikkola, Maria A Andersson, Marika Jestoi, Mirja Salkinoja-Salonen. Streptomyces strains producing mitochondriotoxic antimycin A found in cereal grains.
International journal of food microbiology.
2016 Feb; 218(?):78-85. doi:
10.1016/j.ijfoodmicro.2015.11.007
. [PMID: 26619316] - Deserah D Strand, Nicholas Fisher, Geoffry A Davis, David M Kramer. Redox regulation of the antimycin A sensitive pathway of cyclic electron flow around photosystem I in higher plant thylakoids.
Biochimica et biophysica acta.
2016 Jan; 1857(1):1-6. doi:
10.1016/j.bbabio.2015.07.012
. [PMID: 26235611] - Marleen Forkink, Farhan Basit, José Teixeira, Herman G Swarts, Werner J H Koopman, Peter H G M Willems. Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells.
Redox biology.
2015 Dec; 6(?):607-616. doi:
10.1016/j.redox.2015.09.003
. [PMID: 26516986] - Zhihui Zhu, Rongyu Li, Rolf Stricker, Georg Reiser. Extracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria.
Brain research.
2015 Sep; 1620(?):17-28. doi:
10.1016/j.brainres.2015.05.011
. [PMID: 25998538] - Beth Szyszka-Mroz, Paula Pittock, Alexander G Ivanov, Gilles Lajoie, Norman P A Hüner. The Antarctic Psychrophile Chlamydomonas sp. UWO 241 Preferentially Phosphorylates a Photosystem I-Cytochrome b6/f Supercomplex.
Plant physiology.
2015 Sep; 169(1):717-36. doi:
10.1104/pp.15.00625
. [PMID: 26169679] - Abhaypratap Vishwakarma, Sarada Devi Tetali, Jennifer Selinski, Renate Scheibe, Kollipara Padmasree. Importance of the alternative oxidase (AOX) pathway in regulating cellular redox and ROS homeostasis to optimize photosynthesis during restriction of the cytochrome oxidase pathway in Arabidopsis thaliana.
Annals of botany.
2015 Sep; 116(4):555-69. doi:
10.1093/aob/mcv122
. [PMID: 26292995] - Daniela Ottaviano, Arianna Montanari, Lorenzo De Angelis, Rosa Santomartino, Andrea Visca, Luca Brambilla, Teresa Rinaldi, Cristiano Bello, Massimo Reverberi, Michele M Bianchi. Unsaturated fatty acids-dependent linkage between respiration and fermentation revealed by deletion of hypoxic regulatory KlMGA2 gene in the facultative anaerobe-respiratory yeast Kluyveromyces lactis.
FEMS yeast research.
2015 Aug; 15(5):fov028. doi:
10.1093/femsyr/fov028
. [PMID: 26019145] - Sreedhar Nellaepalli, Sireesha Kodru, Agepati S Raghavendra, Rajagopal Subramanyam. Antimycin A sensitive pathway independent from PGR5 cyclic electron transfer triggers non-photochemical reduction of PQ pool and state transitions in Arabidopsis thaliana.
Journal of photochemistry and photobiology. B, Biology.
2015 May; 146(?):24-33. doi:
10.1016/j.jphotobiol.2015.02.013
. [PMID: 25792151] - Marianna D'Arco, Wojciech Margas, John S Cassidy, Annette C Dolphin. The upregulation of α2δ-1 subunit modulates activity-dependent Ca2+ signals in sensory neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2015 Apr; 35(15):5891-903. doi:
10.1523/jneurosci.3997-14.2015
. [PMID: 25878262] - Yi Zhang, Lu Qu, Lili Liu, Xiaoxia Li, Erwei Liu, Lifeng Han, Shiming Fang, Xiumei Gao, Tao Wang. New maltol glycosides from Flos Sophorae.
Journal of natural medicines.
2015 Apr; 69(2):249-54. doi:
10.1007/s11418-014-0877-1
. [PMID: 25398298] - Serkan Erdal, Mucip Genisel, Hulya Turk, Rahmi Dumlupinar, Yavuz Demir. Modulation of alternative oxidase to enhance tolerance against cold stress of chickpea by chemical treatments.
Journal of plant physiology.
2015 Mar; 175(?):95-101. doi:
10.1016/j.jplph.2014.10.014
. [PMID: 25543861] - Nicholas Fisher, David M Kramer. Non-photochemical reduction of thylakoid photosynthetic redox carriers in vitro: relevance to cyclic electron flow around photosystem I?.
Biochimica et biophysica acta.
2014 Dec; 1837(12):1944-1954. doi:
10.1016/j.bbabio.2014.09.005
. [PMID: 25251244] - Natalia Mallo, Jesús Lamas, José M Leiro. Alternative oxidase inhibitors as antiparasitic agents against scuticociliatosis.
Parasitology.
2014 Sep; 141(10):1311-21. doi:
10.1017/s0031182014000572
. [PMID: 24824550] - Keisuke Yoshida, Yuta Matsuoka, Satoshi Hara, Hiroki Konno, Toru Hisabori. Distinct redox behaviors of chloroplast thiol enzymes and their relationships with photosynthetic electron transport in Arabidopsis thaliana.
Plant & cell physiology.
2014 Aug; 55(8):1415-25. doi:
10.1093/pcp/pcu066
. [PMID: 24850837] - Nicolás E Blanco, Manuel Guinea-Díaz, James Whelan, Åsa Strand. Interaction between plastid and mitochondrial retrograde signalling pathways during changes to plastid redox status.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
2014 Apr; 369(1640):20130231. doi:
10.1098/rstb.2013.0231
. [PMID: 24591717] - Younes Filali-Zegzouti, Jean-Louis Rouanet, Toufiq Fechtali, Damien Roussel. Mitochondrial oxidative energy metabolism in guanethidine-induced sympathectomized ducklings.
General physiology and biophysics.
2014; 33(1):91-7. doi:
10.4149/gpb_2013072
. [PMID: 24334534] - Jianchun Chen, Jian-Kang Chen, Edward M Conway, Raymond C Harris. Survivin mediates renal proximal tubule recovery from AKI.
Journal of the American Society of Nephrology : JASN.
2013 Dec; 24(12):2023-33. doi:
10.1681/asn.2013010076
. [PMID: 23949800] - Eun Mi Choi, Young Soon Lee. Paeoniflorin isolated from Paeonia lactiflora attenuates osteoblast cytotoxicity induced by antimycin A.
Food & function.
2013 Sep; 4(9):1332-8. doi:
10.1039/c3fo60147a
. [PMID: 23824342] - Nancy R Hofmann. Endoplasmic reticulum-localized transcription factors and mitochondrial retrograde regulation.
The Plant cell.
2013 Sep; 25(9):3151. doi:
10.1105/tpc.113.250912
. [PMID: 24045018] - Kazuhiko Sugimoto, Yuki Okegawa, Akihiko Tohri, Terri A Long, Sarah F Covert, Toru Hisabori, Toshiharu Shikanai. A single amino acid alteration in PGR5 confers resistance to antimycin A in cyclic electron transport around PSI.
Plant & cell physiology.
2013 Sep; 54(9):1525-34. doi:
10.1093/pcp/pct098
. [PMID: 23872270] - Gerhard Obermeyer, Lena Fragner, Veronika Lang, Wolfram Weckwerth. Dynamic adaption of metabolic pathways during germination and growth of lily pollen tubes after inhibition of the electron transport chain.
Plant physiology.
2013 Aug; 162(4):1822-33. doi:
10.1104/pp.113.219857
. [PMID: 23660836] - A-Rang Im, Young-Hwa Kim, Md Romij Uddin, Seong Wook Chae, Hye Won Lee, Woo Suk Jung, Yun Hee Kim, Bong Ju Kang, Yeong Shik Kim, Mi-Young Lee. Protection from antimycin A-induced mitochondrial dysfunction by Nelumbo nucifera seed extracts.
Environmental toxicology and pharmacology.
2013 Jul; 36(1):19-29. doi:
10.1016/j.etap.2013.02.015
. [PMID: 23542413] - Bavneet Benipal, Lawrence H Lash. Modulation of mitochondrial glutathione status and cellular energetics in primary cultures of proximal tubular cells from remnant kidney of uninephrectomized rats.
Biochemical pharmacology.
2013 May; 85(9):1379-88. doi:
10.1016/j.bcp.2013.02.013
. [PMID: 23419872] - Lika Nesuashvili, Stephen H Hadley, Parmvir K Bahia, Thomas E Taylor-Clark. Sensory nerve terminal mitochondrial dysfunction activates airway sensory nerves via transient receptor potential (TRP) channels.
Molecular pharmacology.
2013 May; 83(5):1007-19. doi:
10.1124/mol.112.084319
. [PMID: 23444014] - Marina Cvetkovska, Greg C Vanlerberghe. Alternative oxidase impacts the plant response to biotic stress by influencing the mitochondrial generation of reactive oxygen species.
Plant, cell & environment.
2013 Mar; 36(3):721-32. doi:
10.1111/pce.12009
. [PMID: 22978428] - Eun Mi Choi. Deoxyactein stimulates osteoblast function and inhibits bone-resorbing mediators in MC3T3-E1 cells.
Journal of applied toxicology : JAT.
2013 Mar; 33(3):190-5. doi:
10.1002/jat.1733
. [PMID: 21910134] - Jong H Kim, Bruce C Campbell, Kathleen L Chan, Noreen Mahoney, Ronald P Haff. Synergism of antifungal activity between mitochondrial respiration inhibitors and kojic acid.
Molecules (Basel, Switzerland).
2013 Jan; 18(2):1564-81. doi:
10.3390/molecules18021564
. [PMID: 23353126] - Anthony L Moore, Tomoo Shiba, Luke Young, Shigeharu Harada, Kiyoshi Kita, Kikukatsu Ito. Unraveling the heater: new insights into the structure of the alternative oxidase.
Annual review of plant biology.
2013; 64(?):637-63. doi:
10.1146/annurev-arplant-042811-105432
. [PMID: 23638828] - Marcus Wallgren, Martin Lidman, Anders Pedersen, Kristoffer Brännström, B Göran Karlsson, Gerhard Gröbner. Reconstitution of the anti-apoptotic Bcl-2 protein into lipid membranes and biophysical evidence for its detergent-driven association with the pro-apoptotic Bax protein.
PloS one.
2013; 8(4):e61452. doi:
10.1371/journal.pone.0061452
. [PMID: 23626686] - Matteo Lulli, Ewa Witort, Laura Papucci, Eugenio Torre, Christian Schipani, Christian Bergamini, Massimo Dal Monte, Sergio Capaccioli. Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage.
Investigative ophthalmology & visual science.
2012 Dec; 53(13):8295-302. doi:
10.1167/iovs.12-10374
. [PMID: 23154463] - Anne Marie Allen, Annette Graham. Mitochondrial function is involved in regulation of cholesterol efflux to apolipoprotein (apo)A-I from murine RAW 264.7 macrophages.
Lipids in health and disease.
2012 Dec; 11(?):169. doi:
10.1186/1476-511x-11-169
. [PMID: 23227865] - Yuri Nishikawa, Hiroshi Yamamoto, Yuki Okegawa, Shinya Wada, Nozomi Sato, Yoshichika Taira, Kazuhiko Sugimoto, Amane Makino, Toshiharu Shikanai. PGR5-dependent cyclic electron transport around PSI contributes to the redox homeostasis in chloroplasts rather than CO(2) fixation and biomass production in rice.
Plant & cell physiology.
2012 Dec; 53(12):2117-26. doi:
10.1093/pcp/pcs153
. [PMID: 23161858] - Minoru Ueda, Tetsuki Kuniyoshi, Hiroshi Yamamoto, Kazuhiko Sugimoto, Kimitsune Ishizaki, Takayuki Kohchi, Yoshiki Nishimura, Toshiharu Shikanai. Composition and physiological function of the chloroplast NADH dehydrogenase-like complex in Marchantia polymorpha.
The Plant journal : for cell and molecular biology.
2012 Nov; 72(4):683-93. doi:
10.1111/j.1365-313x.2012.05115.x
. [PMID: 22862786] - Frank E Nargang, Kelly Adames, Cornelia Rüb, Serena Cheung, Nancy Easton, Cheryl E Nargang, Michael S Chae. Identification of genes required for alternative oxidase production in the Neurospora crassa gene knockout library.
G3 (Bethesda, Md.).
2012 Nov; 2(11):1345-56. doi:
10.1534/g3.112.004218
. [PMID: 23173086] - Sung-Jun Lee, Eun-Ae Kim, Kyoung Seob Song, Min-Jae Kim, Dae Hyung Lee, Taeg Kyu Kwon, Tae-Jin Lee. Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2.
International journal of oncology.
2012 Oct; 41(4):1425-30. doi:
10.3892/ijo.2012.1575
. [PMID: 22842544] - Xiaoming Zhou, Maurice B Burg, Joan D Ferraris. Water restriction increases renal inner medullary manganese superoxide dismutase (MnSOD).
American journal of physiology. Renal physiology.
2012 Sep; 303(5):F674-80. doi:
10.1152/ajprenal.00076.2012
. [PMID: 22718889] - Eun Mi Choi, Young Soon Lee. Protective effect of apocynin on antimycin A-induced cell damage in osteoblastic MC3T3-E1 cells.
Journal of applied toxicology : JAT.
2012 Sep; 32(9):714-21. doi:
10.1002/jat.1689
. [PMID: 21538410] - Yew-Foon Tan, A Harvey Millar, Nicolas L Taylor. Components of mitochondrial oxidative phosphorylation vary in abundance following exposure to cold and chemical stresses.
Journal of proteome research.
2012 Jul; 11(7):3860-79. doi:
10.1021/pr3003535
. [PMID: 22574745] - Eun Mi Choi. Magnolol protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity through activation of mitochondrial function.
Inflammation.
2012 Jun; 35(3):1204-12. doi:
10.1007/s10753-012-9430-0
. [PMID: 22281543] - Alberto González, M de Los Ángeles Cabrera, M Josefa Henríquez, Rodrigo A Contreras, Bernardo Morales, Alejandra Moenne. Cross talk among calcium, hydrogen peroxide, and nitric oxide and activation of gene expression involving calmodulins and calcium-dependent protein kinases in Ulva compressa exposed to copper excess.
Plant physiology.
2012 Mar; 158(3):1451-62. doi:
10.1104/pp.111.191759
. [PMID: 22234999] - Ruth Chang, Charles J H Jang, Cristina Branco-Price, Peter Nghiem, Julia Bailey-Serres. Transient MPK6 activation in response to oxygen deprivation and reoxygenation is mediated by mitochondria and aids seedling survival in Arabidopsis.
Plant molecular biology.
2012 Jan; 78(1-2):109-22. doi:
10.1007/s11103-011-9850-5
. [PMID: 22086331] - Ann L Umbach, Jelena Zarkovic, Jianping Yu, Michael E Ruckle, Lee McIntosh, Jeffery J Hock, Scott Bingham, Samuel J White, Rajani M George, Chalivendra C Subbaiah, David M Rhoads. Comparison of intact Arabidopsis thaliana leaf transcript profiles during treatment with inhibitors of mitochondrial electron transport and TCA cycle.
PloS one.
2012; 7(9):e44339. doi:
10.1371/journal.pone.0044339
. [PMID: 23028523] - Yusuke Ohsaki, Paul O'Connor, Takefumi Mori, Robert P Ryan, Bryan C Dickinson, Christopher J Chang, Yi Lu, Sadayoshi Ito, Allen W Cowley. Increase of sodium delivery stimulates the mitochondrial respiratory chain H2O2 production in rat renal medullary thick ascending limb.
American journal of physiology. Renal physiology.
2012 Jan; 302(1):F95-F102. doi:
10.1152/ajprenal.00469.2011
. [PMID: 21975873] - Patricia W Seo-Mayer, Gunilla Thulin, Li Zhang, Daiane S Alves, Thomas Ardito, Michael Kashgarian, Michael J Caplan. Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.
American journal of physiology. Renal physiology.
2011 Dec; 301(6):F1346-57. doi:
10.1152/ajprenal.00420.2010
. [PMID: 21849490] - Eun Mi Choi. Honokiol protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2011 Nov; 60(11):1005-12. doi:
10.1007/s00011-011-0360-3
. [PMID: 21800176] - Takashi Masuda, Yukio Iwashita, Satoshi Hagiwara, Masayuki Ohta, Masafumi Inomata, Takayuki Noguchi, Seigo Kitano. Dihydrolipoyl histidinate zinc complex, a new antioxidant, attenuates hepatic ischemia-reperfusion injury in rats.
Journal of gastroenterology and hepatology.
2011 Nov; 26(11):1652-8. doi:
10.1111/j.1440-1746.2011.06773.x
. [PMID: 22011298] - Eun Mi Choi. Honokiol isolated from Magnolia officinalis stimulates osteoblast function and inhibits the release of bone-resorbing mediators.
International immunopharmacology.
2011 Oct; 11(10):1541-5. doi:
10.1016/j.intimp.2011.05.011
. [PMID: 21621646] - Eun Mi Choi. Dehydrocostus lactone prevents mitochondrial dysfunction in osteoblastic MC3T3-E1 cells.
European journal of pharmacology.
2011 Aug; 664(1-3):1-7. doi:
10.1016/j.ejphar.2011.05.005
. [PMID: 21596031] - Konstanze Plaschke, Marion Bergmann, Jürgen Kopitz. Ginkgo extract EGb 761(®) shields from slowly accumulating neurodegenerative-like changes in a newly developed cell culture model induced by the combined action of low doses of antimycin A1 and 2-deoxy-D-glucose.
Journal of neural transmission (Vienna, Austria : 1996).
2011 Aug; 118(8):1247-54. doi:
10.1007/s00702-011-0637-2
. [PMID: 21479515] - Leonid V Savitch, Alexander G Ivanov, Loreta Gudynaite-Savitch, Norman P A Huner, John Simmonds. Cold stress effects on PSI photochemistry in Zea mays: differential increase of FQR-dependent cyclic electron flow and functional implications.
Plant & cell physiology.
2011 Jun; 52(6):1042-54. doi:
10.1093/pcp/pcr056
. [PMID: 21546369] - I Yu Subota, A Sh Arziev, G A Nevinsky, Yu M Konstantinov. Effect of redox conditions on the synthesis and phosphorylation of β-subunit of mitochondrial F(0)F (1)-ATPase of maize (Zea mays).
Doklady. Biochemistry and biophysics.
2011 May; 438(?):144-6. doi:
10.1134/s1607672911030100
. [PMID: 21725894] - Jong H Kim, Bruce C Campbell, Noreen Mahoney, Kathleen L Chan, Russell J Molyneux. Chemosensitization of aflatoxigenic fungi to antimycin A and strobilurin using salicylaldehyde, a volatile natural compound targeting cellular antioxidation system.
Mycopathologia.
2011 Apr; 171(4):291-8. doi:
10.1007/s11046-010-9356-8
. [PMID: 20803256] - Lesław B Lahuta, Tomasz Dzik. D-chiro-inositol affects accumulation of raffinose family oligosaccharides in developing embryos of Pisum sativum.
Journal of plant physiology.
2011 Mar; 168(4):352-8. doi:
10.1016/j.jplph.2010.07.027
. [PMID: 20947202] - Saikrishna Talla, Khateef Riazunnisa, Lolla Padmavathi, Bobba Sunil, Pidakala Rajsheel, Agepati S Raghavendra. Ascorbic acid is a key participant during the interactions between chloroplasts and mitochondria to optimize photosynthesis and protect against photoinhibition.
Journal of biosciences.
2011 Mar; 36(1):163-73. doi:
10.1007/s12038-011-9000-x
. [PMID: 21451257] - Wing-Sham Lee, Shih-Feng Fu, Jeanmarie Verchot-Lubicz, John P Carr. Genetic modification of alternative respiration in Nicotiana benthamiana affects basal and salicylic acid-induced resistance to potato virus X.
BMC plant biology.
2011 Feb; 11(?):41. doi:
10.1186/1471-2229-11-41
. [PMID: 21356081] - Vicente P Martins, Taisa M Dinamarco, Frederico M Soriani, Valéria G Tudella, Sergio C Oliveira, Gustavo H Goldman, Carlos Curti, Sérgio A Uyemura. Involvement of an alternative oxidase in oxidative stress and mycelium-to-yeast differentiation in Paracoccidioides brasiliensis.
Eukaryotic cell.
2011 Feb; 10(2):237-48. doi:
10.1128/ec.00194-10
. [PMID: 21183691] - Mary S Albury, Catherine Elliott, Anthony L Moore. Ubiquinol-binding site in the alternative oxidase: mutagenesis reveals features important for substrate binding and inhibition.
Biochimica et biophysica acta.
2010 Dec; 1797(12):1933-9. doi:
10.1016/j.bbabio.2010.01.013
. [PMID: 20085745] - Gunjan Guha, Tamoghna Mandal, V Rajkumar, R Ashok Kumar. Antimycin A-induced mitochondrial apoptotic cascade is mitigated by phenolic constituents of Phyllanthus amarus aqueous extract in Hep3B cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2010 Dec; 48(12):3449-57. doi:
10.1016/j.fct.2010.09.020
. [PMID: 20854871] - June Woo Lee, Won Ho Kim, Jiyoung Yeo, Myeong Ho Jung. ER stress is implicated in mitochondrial dysfunction-induced apoptosis of pancreatic beta cells.
Molecules and cells.
2010 Dec; 30(6):545-9. doi:
10.1007/s10059-010-0161-5
. [PMID: 21340672] - Cleverson Busso, Erich B Tahara, Renata Ogusucu, Ohara Augusto, Jose Ribamar Ferreira-Junior, Alexander Tzagoloff, Alicia J Kowaltowski, Mario H Barros. Saccharomyces cerevisiae coq10 null mutants are responsive to antimycin A.
The FEBS journal.
2010 Nov; 277(21):4530-8. doi:
10.1111/j.1742-4658.2010.07862.x
. [PMID: 20875086] - Ataru Higa, Yuko Mori, Yoshie Kitamura. Iron deficiency induces changes in riboflavin secretion and the mitochondrial electron transport chain in hairy roots of Hyoscyamus albus.
Journal of plant physiology.
2010 Jul; 167(11):870-8. doi:
10.1016/j.jplph.2010.01.011
. [PMID: 20181408]