cis-4-hydroxyproline (BioDeep_00000400076)
Secondary id: BioDeep_00000014813
natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds
代谢物信息卡片
cis-4-Hydroxy-D-proline
化学式: C5H9NO3 (131.0582404)
中文名称: 顺-4-羟基-D-脯氨酸, 顺式-4-羟基-D-脯氨酸
谱图信息:
最多检出来源 Viridiplantae(plant) 0.94%
分子结构信息
SMILES: C1C(CNC1C(=O)O)O
InChI: InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
描述信息
A 4-hydroxy-D-proline in which the hydroxy group at position 4 has R-configuration.
cis-4-Hydroxy-D-proline is a precursor of conformationally restricted PNA adenine monomer. cis-4-Hydroxy-D-proline can be used to study the specificity and kinetics of D-alanine dehydrogenase[1][2].
同义名列表
数据库引用编号
25 个数据库交叉引用编号
- ChEBI: CHEBI:63727
- ChEBI: CHEBI:16231
- KEGG: C03440
- PubChem: 6971054
- PubChem: 440014
- ChEMBL: CHEMBL1229563
- MeSH: Hydroxyproline
- CAS: 2584-71-6
- MoNA: CCMSLIB00005463964
- MoNA: CCMSLIB00005463978
- MoNA: CCMSLIB00005720474
- MoNA: CCMSLIB00005720767
- MoNA: EMBL-MCF_spec129109
- MoNA: EMBL-MCF_spec129069
- MoNA: EMBL-MCF_spec60943
- MoNA: CCMSLIB00000578280
- MetaboLights: MTBLC16231
- PubChem: 6264
- PDB-CCD: UYA
- 3DMET: B01659
- NIKKAJI: J192.095B
- RefMet: cis-4-Hydroxyproline
- medchemexpress: HY-W008129
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-323
- KNApSAcK: 16231
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 569774 - 金线莲: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kyohei Takano, Marisa Kaneda, Yayoi Aoki, Nina Fujita, Shigeki Chiba, Seiwa Michihara, Li-Kun Han, Ryuji Takahashi. The protective effects of Ninjin'yoeito against liver steatosis/fibrosis in a non-alcoholic steatohepatitis model mouse.
Journal of natural medicines.
2024 Jun; 78(3):514-524. doi:
10.1007/s11418-024-01786-2. [PMID: 38498120] - Manar M Abu-Nawareg, Hanan K Abouelseoud, Ahmed Z Zidan. Effect of Salvadora persica on resin-dentin bond stability.
BMC oral health.
2024 Apr; 24(1):505. doi:
10.1186/s12903-024-04244-3. [PMID: 38684974] - Nimra Riasat, Muniba Jadoon, Nosheen Akhtar, Marya Nawaz Kiani, Humaira Fatima, Mostafa A Abdel-Maksoud, Syeda Masooma Ali, Akram A Alfuraydi, M Junaid Dar, Ihsan Ul Haq. Polyphenolic characterization and biological assessment of Acacia nilotica (L.) wild. Ex delilie: An In vitro and In vivo appraisal of wound healing potential.
Journal of ethnopharmacology.
2024 Feb; ?(?):117842. doi:
10.1016/j.jep.2024.117842. [PMID: 38310987] - Esra Kupeli Akkol, Muberra Kosar, Ayse Baldemir, Gökçe Şeker Karatoprak, Eren Demirpolat, Mukerrem Betul Yerer Aycan, Ipek Suntar, Selen Ilgun. THE WOUND HEALING POTENTIAL OF THE ENDEMIC PLANT HELIANTHEMUM CANUM (L.) BAUMG: PRECLINICAL STUDIES SUPPORTED WITH PHYTOCHEMICAL PROFILING.
Chemistry & biodiversity.
2023 Nov; ?(?):e202301529. doi:
10.1002/cbdv.202301529. [PMID: 37955210] - Shanshan Wang, Fei Ye, Qingjia Ren, Shengnan Sun, Weina Xia, Zhuwei Wang, Haolin Guo, Han Li, Shujing Zhang, Scott Lowe, Meng Chen, Qinghong Du, Weihong Li. The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro.
Journal of ethnopharmacology.
2023 Oct; ?(?):117283. doi:
10.1016/j.jep.2023.117283. [PMID: 37827298] - Nicole Canon, Catherine H Schein, Werner Braun, Surendra S Negi, Xueni Chen, Michael D Kulis, Edwin H Kim, Vidya Pathy, Marina Pozzoli, Weimin Liu, Stephen C Dreskin. Alanine Scanning of the Unstructured Region of Ara h 2 and of a Related Mimotope Reveals Critical Amino Acids for IgE Binding.
Molecular nutrition & food research.
2023 Sep; ?(?):e2300134. doi:
10.1002/mnfr.202300134. [PMID: 37706599] - Uddhab Karki, Paula Perez Sanchez, Sankalpa Chakraborty, Berry Dickey, Jacqueline Vargas Ulloa, Ningning Zhang, Jianfeng Xu. Intracellular trafficking and glycosylation of hydroxyproline-O-glycosylation module in tobacco BY-2 cells is dependent on medium composition and transcriptome analysis.
Scientific reports.
2023 08; 13(1):13506. doi:
10.1038/s41598-023-40723-3. [PMID: 37598266] - Yang Liu, Amei Tang, Ming Liu, Changjun Xu, Feng Cao, Changfu Yang. Tuberostemonine may enhance the function of the SLC7A11/glutamate antiporter to restrain the ferroptosis to alleviate pulmonary fibrosis.
Journal of ethnopharmacology.
2023 Aug; 318(Pt B):116983. doi:
10.1016/j.jep.2023.116983. [PMID: 37532076] - Xiaojia He, Zachery R Jarrell, Matthew Ryan Smith, ViLinh Thi Ly, Xin Hu, Viranuj Sueblinvong, Yongliang Liang, Michael Orr, Young-Mi Go, Dean P Jones. Low-dose vanadium pentoxide perturbed lung metabolism associated with inflammation and fibrosis signaling in male animal and in vitro models.
American journal of physiology. Lung cellular and molecular physiology.
2023 Jun; ?(?):. doi:
10.1152/ajplung.00303.2022. [PMID: 37310758] - Bo Bao, Jinpeng Liu, Tuling Li, Zhaohui Yang, Guimin Wang, Jizhao Xin, Hongsheng Bi, Dadong Guo. Elevated retinal fibrosis in experimental myopia is involved in the activation of the PI3K/AKT/ERK signaling pathway.
Archives of biochemistry and biophysics.
2023 Jun; 743(?):109663. doi:
10.1016/j.abb.2023.109663. [PMID: 37290701] - Syeda Roop Fatima Jaffri, Holly Scheer, Cora A MacAlister. The hydroxyproline O-arabinosyltransferase FIN4 is required for tomato pollen intine development.
Plant reproduction.
2023 06; 36(2):173-191. doi:
10.1007/s00497-023-00459-6. [PMID: 36749417] - Jasper W van de Sande, Bauke Albada. Chemical Synthesis of Glycopeptides containing l-Arabinosylated Hydroxyproline and Sulfated Tyrosine.
Organic letters.
2023 03; 25(11):1907-1911. doi:
10.1021/acs.orglett.3c00411. [PMID: 36917069] - Usama W Hawas, Mohamed A El-Ansari, Abeer F Osman, Asmaa F Galal, Lamia T Abou El-Kassem. Flavonoid constituents and protective efficacy of Citrus reticulate (Blanco) leaves ethanolic extract on thioacetamide-induced liver injury rats.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2023 Mar; 28(2):160-167. doi:
10.1080/1354750x.2022.2151645. [PMID: 36420657] - Alankar Shrivastav, Arun Kumar Mishra, Asheessh Kumar Gupta. Evaluation of Wound Healing Potential of Root Bark Extract of Berberis Aristata and Molecular Docking Analysis of Berberis Phytoconstituents.
Current drug discovery technologies.
2023 Feb; ?(?):. doi:
10.2174/1570163820666230221154851. [PMID: 36824006] - Diana Moreira, Dasmeet Kaur, Ana Marta Pereira, Michael A Held, Allan M Showalter, Sílvia Coimbra. Type II arabinogalactans initiated by hydroxyproline-O-galactosyltransferases play important roles in pollen - pistil interactions.
The Plant journal : for cell and molecular biology.
2023 Feb; ?(?):. doi:
10.1111/tpj.16141. [PMID: 36775989] - Ashkan Karbasi, Anahita Abbasifard, Farzin Firouzian, Sara Soleimani Asl, Zahra Azizi, Akram Ranjbar. Is nanoparaquat safer than bulk paraquat? An in vitro and in vivo evaluation.
Toxicology.
2023 01; 484(?):153398. doi:
10.1016/j.tox.2022.153398. [PMID: 36535436] - Akihiro Ishiwata, Hanako Tsunomachi, Kyohei Kameyama, Kaeothip Sophon, Masayuki Nakamura, Kanefumi Kitahara, Katsunori Tanaka, Yukishige Ito, Kiyotaka Fujita. Bifidobacterial GH146 β-l-Arabinofuranosidase (Bll4HypBA1) as the Last Enzyme for the Complete Removal of Oligoarabinofuranosides from Hydroxyproline-Rich Glycoproteins.
Chembiochem : a European journal of chemical biology.
2022 Dec; ?(?):e202200637. doi:
10.1002/cbic.202200637. [PMID: 36579407] - Monika Kopečná, Miloslav Macháček, Jaroslav Roh, Kateřina Vávrová. Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversible transdermal permeation enhancers.
Scientific reports.
2022 11; 12(1):19495. doi:
10.1038/s41598-022-24108-6. [PMID: 36376455] - Ahmad Za'al Alsarayreh, Sawsan Attalah Oran, Jumah Mutie Shakhanbeh. In vitro and in vivo wound healing activities of Globularia arabica leaf methanolic extract in diabetic rats.
Journal of cosmetic dermatology.
2022 Oct; 21(10):4888-4900. doi:
10.1111/jocd.14882. [PMID: 35212131] - Amir Siahpoosh, Alireza Malayeri, Anayatollah Salimi, Layasadat Khorsandi, Zeinab Zaheri Abdevand. Determination of the effectiveness of Dorema ammoniacum gum on wound healing: an experimental study.
Journal of wound care.
2022 Oct; 31(Sup10):S16-S27. doi:
10.12968/jowc.2022.31.sup10.s16. [PMID: 36240871] - Xueyan Zhang, Ruijie Wang, Jian Lv, Qing Sun. Q-Switched 1064 nm Nd:YAG Laser Rejuvenates Photoaging Skin of Rats by Downregulating miR-196b-5p.
Photobiomodulation, photomedicine, and laser surgery.
2022 Oct; 40(10):708-714. doi:
10.1089/photob.2022.0036. [PMID: 36286575] - Puneet Gupta, Ashish Singh, Neelam Singh, Faraat Ali, Ayushi Tyagi, Sadish K Shanmugam. Healing Potential of Propolis Extract-Passiflora edulis Seed Oil Emulgel Against Excisional Wound: Biochemical, Histopathological, and Cytokines Level Evidence.
Assay and drug development technologies.
2022 10; 20(7):300-316. doi:
10.1089/adt.2022.075. [PMID: 36269233] - Heather G Marco, Simone König, Gerd Gäde. Mass Spectrometric Proof of Predicted Peptides: Novel Adipokinetic Hormones in Insects.
Molecules (Basel, Switzerland).
2022 Oct; 27(19):. doi:
10.3390/molecules27196469. [PMID: 36235010] - Parveen Kumar, Zhengqin Yang, Jeremie M Lever, Miranda D Chávez, Huma Fatima, David K Crossman, Craig L Maynard, James F George, Tanecia Mitchell. Hydroxyproline stimulates inflammation and reprograms macrophage signaling in a rat kidney stone model.
Biochimica et biophysica acta. Molecular basis of disease.
2022 09; 1868(9):166442. doi:
10.1016/j.bbadis.2022.166442. [PMID: 35562038] - Ahmad Za'al Alsarayreh, Sawsan Atallah Oran, Jumah Mutie Shakhanbeh. Effect of Rhus coriaria L. methanolic fruit extract on wound healing in diabetic and non-diabetic rats.
Journal of cosmetic dermatology.
2022 Aug; 21(8):3567-3577. doi:
10.1111/jocd.14668. [PMID: 34928525] - Cecilia M Lara-Mondragón, Alexandria Dorchak, Cora A MacAlister. O-glycosylation of the extracellular domain of pollen class I formins modulates their plasma membrane mobility.
Journal of experimental botany.
2022 06; 73(12):3929-3945. doi:
10.1093/jxb/erac131. [PMID: 35383367] - Huahong Yang, Lidong Wang, Manshi Yang, Jianqiang Hu, Erli Zhang, Liping Peng. Oridonin attenuates LPS-induced early pulmonary fibrosis by regulating impaired autophagy, oxidative stress, inflammation and EMT.
European journal of pharmacology.
2022 May; 923(?):174931. doi:
10.1016/j.ejphar.2022.174931. [PMID: 35398392] - Yanfeng Li, Miaomiao Li, Rui Wang, Biyu Wang, Seyyed Shamsadin Athari, Jinli Wang. Ganoderma modulates allergic asthma pathologic features via anti-inflammatory effects.
Respiratory physiology & neurobiology.
2022 05; 299(?):103843. doi:
10.1016/j.resp.2022.103843. [PMID: 35026480] - Shengdi Hu, Wenliang He, Guoyao Wu. Hydroxyproline in animal metabolism, nutrition, and cell signaling.
Amino acids.
2022 Apr; 54(4):513-528. doi:
10.1007/s00726-021-03056-x. [PMID: 34342708] - Lin Han, Yanfang Zou, Chen Yu. Targeting CC chemokine ligand (CCL) 20 by miR-143-5p alleviate lead poisoning-induced renal fibrosis by regulating interstitial fibroblasts excessive proliferation and dysfunction.
Bioengineered.
2022 04; 13(4):11156-11168. doi:
10.1080/21655979.2022.2062106. [PMID: 35485286] - Chan Jung Liu, Yau Sheng Tsai, Ho Shiang Huang. Atorvastatin Decreases Renal Calcium Oxalate Stone Deposits by Enhancing Renal Osteopontin Expression in Hyperoxaluric Stone-Forming Rats Fed a High-Fat Diet.
International journal of molecular sciences.
2022 Mar; 23(6):. doi:
10.3390/ijms23063048. [PMID: 35328466] - Sebastian Kwiatkowski, Maria Bozko, Michal Zarod, Apolonia Witecka, Kubra Kocdemir, Adam K Jagielski, Jakub Drozak. Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104).
The Journal of biological chemistry.
2022 03; 298(3):101708. doi:
10.1016/j.jbc.2022.101708. [PMID: 35150746] - Hussan Omar, Feng Gao, Hyemin Yoo, Odair Bim, Carolina Garcia, Kathy J LePard, John C Mitchell, Gina Agostini-Walesch, Marcela R Carrilho. Changes to dentin extracellular matrix following treatment with plant-based polyphenols.
Journal of the mechanical behavior of biomedical materials.
2022 02; 126(?):105055. doi:
10.1016/j.jmbbm.2021.105055. [PMID: 34929591] - Yu Iwasaki, Mizuho Nakatogawa, Ayaka Shimizu, Yoshio Sato, Yasutaka Shigemura. Comparison of gelatin and low-molecular weight gelatin hydrolysate ingestion on hydroxyproline (Hyp), Pro-Hyp and Hyp-Gly concentrations in human blood.
Food chemistry.
2022 Feb; 369(?):130869. doi:
10.1016/j.foodchem.2021.130869. [PMID: 34461513] - Ruth Belostotsky, Yaacov Frishberg. Catabolism of Hydroxyproline in Vertebrates: Physiology, Evolution, Genetic Diseases and New siRNA Approach for Treatment.
International journal of molecular sciences.
2022 Jan; 23(2):. doi:
10.3390/ijms23021005. [PMID: 35055190] - Xin Xue, Ji-Bo Kang, Xiao Yang, Nan Li, Liang Chang, Juan Ji, Xiang-Kai Meng, Hai-Qing Zhang, Yue Zhong, Shao-Peng Yu, Wen-Yu Wu, Xiao-Long Wang, Nian-Guang Li, Shan-Liang Sun. An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.
European journal of medicinal chemistry.
2022 Jan; 227(?):113871. doi:
10.1016/j.ejmech.2021.113871. [PMID: 34638033] - Shaymaa Fadhel Abbas Albaayit, Rasedee Abdullah, Mohd Hezmee Mohd Noor. Zerumbone-Loaded Nanostructured Lipid Carrier Gel Enhances Wound Healing in Diabetic Rats.
BioMed research international.
2022; 2022(?):1129297. doi:
10.1155/2022/1129297. [PMID: 36124067] - Dasmeet Kaur, Michael A Held, Mountain R Smith, Allan M Showalter. Functional characterization of hydroxyproline-O-galactosyltransferases for Arabidopsis arabinogalactan-protein synthesis.
BMC plant biology.
2021 Dec; 21(1):590. doi:
10.1186/s12870-021-03362-2. [PMID: 34903166] - Bo Lu, Jun Xie, Deyu Fu, Xiaozhe Chen, Mingyi Zhao, Mingtai Gui, Lei Yao, Xunjie Zhou, Jianhua Li. Huoxue Qianyang Qutan recipe attenuates cardiac fibrosis by inhibiting the NLRP3 inflammasome signalling pathway in obese hypertensive rats.
Pharmaceutical biology.
2021 Dec; 59(1):1045-1057. doi:
10.1080/13880209.2021.1953541. [PMID: 34362291] - Fatemeh Kalantari, Ali Ramazani, Mohammad Reza Poor Heravi, Hamideh Aghahosseini, Katarzyna Ślepokura. Magnetic Nanoparticles Functionalized with Copper Hydroxyproline Complexes as an Efficient, Recoverable, and Recyclable Nanocatalyst: Synthesis and Its Catalytic Application in a Tandem Knoevenagel-Michael Cyclocondensation Reaction.
Inorganic chemistry.
2021 Oct; 60(19):15010-15023. doi:
10.1021/acs.inorgchem.1c02470. [PMID: 34533947] - Chidozie I Onwuka, Chibuzo C Uguru, Chidinma I Onwuka, Ambrose E Obiechina. Evaluation of urinary hydroxyproline and creatinine level in patients with benign mandibular odontogenic tumor.
Clinical and experimental dental research.
2021 10; 7(5):934-940. doi:
10.1002/cre2.392. [PMID: 33496059] - Debabrata Dutta, Shakilur Rahman, Gourab Bhattacharje, Swarnendu Bag, Bidhan Chandra Sing, Jyotirmoy Chatterjee, Amit Basak, Amit Kumar Das. Label-Free Method Development for Hydroxyproline PTM Mapping in Human Plasma Proteome.
The protein journal.
2021 10; 40(5):741-755. doi:
10.1007/s10930-021-09984-7. [PMID: 33840009] - Meike Hasenzahl, Mathias Müsken, Sonja Mertsch, Stefan Schrader, Stephan Reichl. Cell sheet technology: Influence of culture conditions on in vitro-cultivated corneal stromal tissue for regenerative therapies of the ocular surface.
Journal of biomedical materials research. Part B, Applied biomaterials.
2021 10; 109(10):1488-1504. doi:
10.1002/jbm.b.34808. [PMID: 33538123] - Takashi Uebanso, Mai Suyama, Takaaki Shimohata, Kazuaki Mawatari, Akira Takahashi. Effect of Vitamin B2-Deficient Diet on Hydroxyproline- or Obesity-Induced Hyperoxaluria in Mice.
Molecular nutrition & food research.
2021 08; 65(15):e2100226. doi:
10.1002/mnfr.202100226. [PMID: 34110671] - Artur Pinski, Alexander Betekhtin, Jolanta Kwasniewska, Lukasz Chajec, Elzbieta Wolny, Robert Hasterok. 3,4-Dehydro-L-proline Induces Programmed Cell Death in the Roots of Brachypodium distachyon.
International journal of molecular sciences.
2021 Jul; 22(14):. doi:
10.3390/ijms22147548. [PMID: 34299166] - Mitra Samareh Fekri, Hamid Reza Poursalehi, Fariba Sharififar, Ali Mandegary, Farzaneh Rostamzadeh, Rahil Mahmoodi. The effects of methanolic extract of Glycyrrhiza glabra on the prevention and treatment of bleomycin-induced pulmonary fibrosis in rat: experimental study.
Drug and chemical toxicology.
2021 Jul; 44(4):365-371. doi:
10.1080/01480545.2019.1606232. [PMID: 31072167] - Tatsuya Hosono, Masashi Bando, Yoshiko Mizushina, Masafumi Sata, Koichi Hagiwara, Yukihiko Sugiyama. Inhibitory effects of somatostatin analogue in bleomycin-induced pulmonary fibrosis.
Experimental lung research.
2021 May; 47(6):280-288. doi:
10.1080/01902148.2021.1916650. [PMID: 33899633] - Ruo-Fei Li, Xin-Yue Chen, Yong Xu, Fan-Chao Feng, Hai-Lang He, Xian-Mei Zhou. Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis.
Journal of ethnopharmacology.
2021 Apr; 269(?):113761. doi:
10.1016/j.jep.2020.113761. [PMID: 33383114] - Georgios Mavropalias, Leslie Calapre, Michael Morici, Tomoko Koeda, Wayne C K Poon, Oliver R Barley, Elin Gray, Anthony J Blazevich, Kazunori Nosaka. Changes in plasma hydroxyproline and plasma cell-free DNA concentrations after higher- versus lower-intensity eccentric cycling.
European journal of applied physiology.
2021 Apr; 121(4):1087-1097. doi:
10.1007/s00421-020-04593-1. [PMID: 33439308] - Jin Yang, Yunyi Le, Tianjiao Wei, Kangli Wang, Kun Yang, Wenhua Xiao, Tianpei Hong, Rui Wei. Non-targeted metabolomic analysis predicts the therapeutic effects of exenatide on endothelial injury in patients with type 2 diabetes.
Journal of diabetes and its complications.
2021 02; 35(2):107797. doi:
10.1016/j.jdiacomp.2020.107797. [PMID: 33293208] - Mohd Hafis Yuswan, Nurul Hanani A Jalil, Haslina Mohamad, Shamsidah Keso, Nurhidayatul Asma Mohamad, Tengku Shahrul Tengku Md Yusoff, Nor Falahiah Ismail, Yanty Noorzianna Abdul Manaf, Amalia Mohd Hashim, Mohd Nasir Mohd Desa, Yus Aniza Yusof, Shuhaimi Mustafa. Hydroxyproline determination for initial detection of halal-critical food ingredients (gelatin and collagen).
Food chemistry.
2021 Feb; 337(?):127762. doi:
10.1016/j.foodchem.2020.127762. [PMID: 32777563] - Pei-Chang Lee, Yun-Chen Hsieh, Teh-Ia Huo, Ueng-Cheng Yang, Chao-Hsiung Lin, Chung-Pin Li, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin, Kuei-Chuan Lee. Active Vitamin D3 Treatment Attenuated Bacterial Translocation via Improving Intestinal Barriers in Cirrhotic Rats.
Molecular nutrition & food research.
2021 02; 65(3):e2000937. doi:
10.1002/mnfr.202000937. [PMID: 33258263] - Pathomwat Wongrattanakamon, Wipawadee Yooin, Busaban Sirithunyalug, Piyarat Nimmanpipug, Supat Jiranusornkul. Tentative Peptide‒Lipid Bilayer Models Elucidating Molecular Behaviors and Interactions Driving Passive Cellular Uptake of Collagen-Derived Small Peptides.
Molecules (Basel, Switzerland).
2021 Jan; 26(3):. doi:
10.3390/molecules26030710. [PMID: 33573083] - Hiroki Ohnari, Masatoshi Sekiya, Eiji Naru, Taku Ogura, Osamu Sakata, Yasuko Obata. Amino Acids and Their N-Acetylated Derivatives Maintain the Skin's Barrier Function.
Chemical & pharmaceutical bulletin.
2021; 69(7):652-660. doi:
10.1248/cpb.c21-00152. [PMID: 34193714] - Abdulrahman E Koshak, Mardi M Algandaby, Mohammad I Mujallid, Ashraf B Abdel-Naim, Nabil A Alhakamy, Usama A Fahmy, Anas Alfarsi, Shaimaa M Badr-Eldin, Thikryat Neamatallah, Mohammed Z Nasrullah, Hossam M Abdallah, Ahmed Esmat. Wound Healing Activity of Opuntia ficus-indica Fixed Oil Formulated in a Self-Nanoemulsifying Formulation.
International journal of nanomedicine.
2021; 16(?):3889-3905. doi:
10.2147/ijn.s299696. [PMID: 34135583] - Julian M Gaitán, Hyo Youl Moon, Matthew Stremlau, Dena B Dubal, Dane B Cook, Ozioma C Okonkwo, Henriette van Praag. Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer's Disease.
Frontiers in endocrinology.
2021; 12(?):660181. doi:
10.3389/fendo.2021.660181. [PMID: 34093436] - Yu Nakanishi, Yasushi Horimasu, Kakuhiro Yamaguchi, Shinjiro Sakamoto, Takeshi Masuda, Taku Nakashima, Shintaro Miyamoto, Hiroshi Iwamoto, Shinichiro Ohshimo, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori. IL-18 binding protein can be a prognostic biomarker for idiopathic pulmonary fibrosis.
PloS one.
2021; 16(6):e0252594. doi:
10.1371/journal.pone.0252594. [PMID: 34086758] - Yanyong Xu, Xiaoli Pan, Shuwei Hu, Yingdong Zhu, Fathima Cassim Bawa, Yuanyuan Li, Liya Yin, Yanqiao Zhang. Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice.
American journal of physiology. Gastrointestinal and liver physiology.
2021 01; 320(2):G166-G174. doi:
10.1152/ajpgi.00315.2020. [PMID: 33325808] - Charles N Zawatsky, Joshua K Park, Jasmina Abdalla, George Kunos, Malliga R Iyer, Resat Cinar. Peripheral Hybrid CB1R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis.
Frontiers in endocrinology.
2021; 12(?):744857. doi:
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Physiologia plantarum.
2020 Dec; 170(4):607-621. doi:
10.1111/ppl.13200. [PMID: 32880978] - ZhengTao Gu, DengHui Xie, CaiQiang Huang, Rui Ding, RongKai Zhang, QingChu Li, ChuangXin Lin, YiYan Qiu. MicroRNA-497 elevation or LRG1 knockdown promotes osteoblast proliferation and collagen synthesis in osteoporosis via TGF-β1/Smads signalling pathway.
Journal of cellular and molecular medicine.
2020 11; 24(21):12619-12632. doi:
10.1111/jcmm.15826. [PMID: 32975015] - Dalene De Beer, Catharina Mc Mels, Aletta E Schutte, Roan Louw, Christian Delles, Ruan Kruger. Left ventricular mass and urinary metabolomics in young black and white adults: The African-PREDICT study.
Nutrition, metabolism, and cardiovascular diseases : NMCD.
2020 10; 30(11):2051-2062. doi:
10.1016/j.numecd.2020.06.004. [PMID: 32669241] - Haidi Huang, Xin Wang, Xue Zhang, Hongbo Wang, Wanglin Jiang. Roxadustat attenuates experimental pulmonary fibrosis in vitro and in vivo.
Toxicology letters.
2020 Oct; 331(?):112-121. doi:
10.1016/j.toxlet.2020.06.009. [PMID: 32534005] - Li Li, Sufang Zhang, Lei Wei, Zhongfu Wang, Wei Ma, Fangying Liu, Yanhua Shen, Shanfang Zhang, Xiulian Zhang, Yu Hang, Yechang Qian. Anti-fibrotic effect of melittin on TRIM47 expression in human embryonic lung fibroblast through regulating TRIM47 pathway.
Life sciences.
2020 Sep; 256(?):117893. doi:
10.1016/j.lfs.2020.117893. [PMID: 32502539] - Shuyun Zhu, Longfang Zheng, Luping Sun, Wenhui Jia, Jing Sun, Xian-En Zhao, Huwei Liu. Derivatization-based magnetic dummy molecularly imprinted polymers integrated with 4-plex stable isotope labeling derivatization strategy for specific and rapid determination of L-hydroxyproline in human serum.
Analytica chimica acta.
2020 Aug; 1127(?):57-68. doi:
10.1016/j.aca.2020.06.045. [PMID: 32800138] - Guixin Li, Junli Zhang, Qianqian Jiang, Beibei Liu, Keshu Xu. CREBH knockout accelerates hepatic fibrosis in mouse models of diet-induced nonalcoholic fatty liver disease.
Life sciences.
2020 Aug; 254(?):117795. doi:
10.1016/j.lfs.2020.117795. [PMID: 32417373] - Steven Beuder, Alexandria Dorchak, Ashwini Bhide, Svenning Rune Moeller, Bent L Petersen, Cora A MacAlister. Exocyst mutants suppress pollen tube growth and cell wall structural defects of hydroxyproline O-arabinosyltransferase mutants.
The Plant journal : for cell and molecular biology.
2020 08; 103(4):1399-1419. doi:
10.1111/tpj.14808. [PMID: 32391581] - Wen-Xin Xiang, Qing Liu, Xiao-Man Li, Chun-Hua Lu, Yue-Mao Shen. Four pairs of proline-containing cyclic dipeptides from Nocardiopsis sp. HT88, an endophytic bacterium of Mallotus nudiflorus L.
Natural product research.
2020 Aug; 34(15):2219-2224. doi:
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Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.
2020 Jul; 28(7):580-585. doi:
10.3760/cma.j.cn501113-20190723-00265. [PMID: 32791793] - Mustafa Gorur, Alper Sozutek, Oktay Irkorucu, Burak Karakaya. The influence of platelet-rich plasma (PRP) on colonic anastomosis healing impaired by intraperitoneal 5-flourouracil application. An experimental study.
Acta cirurgica brasileira.
2020 Jul; 35(5):e202000504. doi:
10.1590/s0102-865020200050000004. [PMID: 32638844] - Rui Zhang, Liming Xu, Xiaoxia An, Xinbing Sui, Shuang Lin. Astragalus polysaccharides attenuate pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition and NF-κB pathway activation.
International journal of molecular medicine.
2020 Jul; 46(1):331-339. doi:
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International journal of molecular sciences.
2020 Jun; 21(11):. doi:
10.3390/ijms21114188. [PMID: 32545390] - Nonawin Lucob-Agustin, Tsubasa Kawai, Misuzu Takahashi-Nosaka, Mana Kano-Nakata, Cornelius M Wainaina, Tomomi Hasegawa, Mayuko Inari-Ikeda, Moeko Sato, Hiroyuki Tsuji, Akira Yamauchi, Yoshiaki Inukai. WEG1, which encodes a cell wall hydroxyproline-rich glycoprotein, is essential for parental root elongation controlling lateral root formation in rice.
Physiologia plantarum.
2020 Jun; 169(2):214-227. doi:
10.1111/ppl.13063. [PMID: 31925781] - Frederico Pecorone Matos, Estélio Henrique Martin Dantas, Flávio Boechat de Oliveira, Juliana Brandão Pinto de Castro, Mario Cezar de S Costa Conceição, Rodolfo de Alkmim Moreira Nunes, Rodrigo Gomes de Souza Vale. Analysis of pain symptoms, flexibility and hydroxyproline concentration in individuals with low back pain submitted to Global Postural Re-education and stretching.
Pain management.
2020 May; 10(3):167-177. doi:
10.2217/pmt-2019-0053. [PMID: 32352877] - Daping Cui, Dewei Zhao, Shibo Huang. Structural characterization of a safflower polysaccharide and its promotion effect on steroid-induced osteonecrosis in vivo.
Carbohydrate polymers.
2020 Apr; 233(?):115856. doi:
10.1016/j.carbpol.2020.115856. [PMID: 32059907] - Hong Fang, Tristen Wright, Jia-Rong Jinn, Wenzheng Guo, Ningning Zhang, Xiaoting Wang, Ya-Jane Wang, Jianfeng Xu. Engineering hydroxyproline-O-glycosylated biopolymers to reconstruct the plant cell wall for improved biomass processability.
Biotechnology and bioengineering.
2020 04; 117(4):945-958. doi:
10.1002/bit.27266. [PMID: 31930479] - Xiangfei Li, Juan Qiao, Zhiwei Li, Li Qi. Fluorescence turn-off-on for highly selective detection of serum l-cysteine based on AuNCs-AuNPs ensembles.
The Analyst.
2020 Mar; 145(6):2233-2237. doi:
10.1039/c9an02495f. [PMID: 32064468] - Hanna Piotrowska-Kempisty, Michał Nowicki, Jadwiga Jodynis-Liebert, Monika Kurpik, Małgorzata Ewertowska, Teresa Adamska, Jan Oszmiański, Małgorzata Kujawska. Assessment of Hepatoprotective Effect of Chokeberry Juice in Rats Treated Chronically with Carbon Tetrachloride.
Molecules (Basel, Switzerland).
2020 Mar; 25(6):. doi:
10.3390/molecules25061268. [PMID: 32168847] - Guoyao Wu. Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health.
Amino acids.
2020 Mar; 52(3):329-360. doi:
10.1007/s00726-020-02823-6. [PMID: 32072297] - Brianna Buchalski, Kyle D Wood, Anil Challa, Sonia Fargue, Ross P Holmes, W Todd Lowther, John Knight. The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria.
Biochimica et biophysica acta. Molecular basis of disease.
2020 03; 1866(3):165633. doi:
10.1016/j.bbadis.2019.165633. [PMID: 31821850] - Imen Trabelsi, Sirine Ben Slima, Naourez Ktari, Sana Bardaa, Karim Elkaroui, Asehraou Abdeslam, Riadh Ben Salah. Purification, composition and biological activities of a novel heteropolysaccharide extracted from Linum usitatissimum L. seeds on laser burn wound.
International journal of biological macromolecules.
2020 Feb; 144(?):781-790. doi:
10.1016/j.ijbiomac.2019.10.077. [PMID: 31678100] - Cecilia M Lara-Mondragón, Cora A MacAlister. Partial purification and immunodetection of cell surface glycoproteins from plants.
Methods in cell biology.
2020; 160(?):215-234. doi:
10.1016/bs.mcb.2020.05.003. [PMID: 32896318] - Amir H Doustimotlagh, Salman Taheri, Mahboubeh Mansourian, Mahdieh Eftekhari. Extraction and Identification of Two Flavonoids in Phlomoides hyoscyamoides as an Endemic Plant of Iran: The Role of Quercetin in the Activation of the Glutathione Peroxidase, the Improvement of the Hydroxyproline and Protein Oxidation in Bile Duct-Ligated Rats.
Current computer-aided drug design.
2020; 16(5):629-640. doi:
10.2174/1573409915666190903163335. [PMID: 31481005] - Sirus Mirzaee, Esrafil Mansouri, Maryam Shirani, Marzieh Zeinvand-Lorestani, Mohammad Javad Khodayar. Diosmin ameliorative effects on oxidative stress and fibrosis in paraquat-induced lung injury in mice.
Environmental science and pollution research international.
2019 Dec; 26(36):36468-36477. doi:
10.1007/s11356-019-06572-2. [PMID: 31732951] - Sonmez Ocak, Omer F Buk, Bugra Genc, Bahattin Avcı, Hatice O Uzuner, Salih B Gundogdu. The effects of platelet-rich-plasma gel application to the colonic anastomosis in hyperthermic intraperitoneal chemotherapy: An experimental rat model.
International wound journal.
2019 Dec; 16(6):1426-1432. doi:
10.1111/iwj.13207. [PMID: 31448554] - Beyazit Garip, Hakan Kayir. Alteration in NMDAR-related amino acids in first episode psychosis.
Synapse (New York, N.Y.).
2019 11; 73(11):e22127. doi:
10.1002/syn.22127. [PMID: 31403728] - Mustafa Alper Akay, Mustafa Akduman, Ahmet Çağrı Tataroğlu, Ceyla Eraldemir, Tuğba Kum, Çiğdem Vural, Gülşen Ekingen Yıldız. Evaluation of the efficacy of Hypericum perforatum (St. John's wort) oil in the prevention of stricture due to esophageal corrosive burns.
Esophagus : official journal of the Japan Esophageal Society.
2019 10; 16(4):352-361. doi:
10.1007/s10388-019-00671-2. [PMID: 30976959] - Oya Ustuner, Ceren Anlas, Tulay Bakirel, Fulya Ustun-Alkan, Belgi Diren Sigirci, Seyyal Ak, Huseyin Askin Akpulat, Ceylan Donmez, Ufuk Koca-Caliskan. In Vitro Evaluation of Antioxidant, Anti-Inflammatory, Antimicrobial and Wound Healing Potential of Thymus Sipyleus Boiss. Subsp. Rosulans (Borbas) Jalas.
Molecules (Basel, Switzerland).
2019 Sep; 24(18):. doi:
10.3390/molecules24183353. [PMID: 31540139] - Pamela Xing Yi Soh, Juliana Maria Marin Cely, Sally-Anne Mortlock, Christopher James Jara, Rachel Booth, Siria Natera, Ute Roessner, Ben Crossett, Stuart Cordwell, Mehar Singh Khatkar, Peter Williamson. Genome-wide association studies of 74 plasma metabolites of German shepherd dogs reveal two metabolites associated with genes encoding their enzymes.
Metabolomics : Official journal of the Metabolomic Society.
2019 09; 15(9):123. doi:
10.1007/s11306-019-1586-2. [PMID: 31493001] - Hossein Sadeghi, Nahid Azarmehr, Fatemeh Razmkhah, Heibatollah Sadeghi, Nazanin Danaei, Navid Omidifar, Hossein Vakilpour, Hossein Pourghadamyari, Amir Hossein Doustimotlagh. The hydroalcoholic extract of watercress attenuates protein oxidation, oxidative stress, and liver damage after bile duct ligation in rats.
Journal of cellular biochemistry.
2019 09; 120(9):14875-14884. doi:
10.1002/jcb.28749. [PMID: 31016763] - Jiafa Ren, Jiandong Zhang, Nathan P Rudemiller, Robert Griffiths, Yi Wen, Xiaohan Lu, Jamie R Privratsky, Michael D Gunn, Steven D Crowley. Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis via Matrix Metallopeptidase 13-Mediated Matrix Degradation.
Journal of the American Society of Nephrology : JASN.
2019 09; 30(9):1674-1685. doi:
10.1681/asn.2018121253. [PMID: 31315922] - Jun Chen, Wenqi Cao, Peixiao Wei, Ting Li, Wuyin Weng. Speciation transformation of arsenic in abalone viscera hydrolysate fraction: In vitro digestion and in vivo metabolism.
Food research international (Ottawa, Ont.).
2019 09; 123(?):340-345. doi:
10.1016/j.foodres.2019.04.062. [PMID: 31284984] - Rebekah D Alcock, Gregory C Shaw, Nicolin Tee, Marijke Welvaert, Louise M Burke. Urinary Hydroxyproline Is Only Suitable As a Biomarker for Acute Intake, Up to 6 hr Postingestion of Collagen Proteins in "Free-Living," Healthy, Active Males.
International journal of sport nutrition and exercise metabolism.
2019 Sep; 29(5):461-465. doi:
10.1123/ijsnem.2019-0024. [PMID: 31444314] - Chun-Fang Fan, Hong-Xia Zhang, Yi-Hao Tang, Hai-Huan Xu, Dong Song. [Preventive and therapeutic effects of safflower water extract on systemic scleroderma in mice and its mechanism].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.
2019 Jul; 35(4):351-354. doi:
10.12047/j.cjap.5785.2019.074. [PMID: 31701721] - R Fernando Martínez, Sarah F Jenkinson, Shinpei Nakagawa, Atsushi Kato, Mark R Wormald, George W J Fleet, Jackie Hollinshead, Robert J Nash. Isolation from Stevia rebaudiana of DMDP acetic acid, a novel iminosugar amino acid: synthesis and glycosidase inhibition profile of glycine and β-alanine pyrrolidine amino acids.
Amino acids.
2019 Jul; 51(7):991-998. doi:
10.1007/s00726-019-02730-5. [PMID: 31079215] - Allen Rodgers, Phindile Cele, Neil Ravenscroft, Cesarina Edmonds-Smith, Graham Jackson. Theoretical and laboratory investigations of the effects of hydroxyproline ingestion on the metabolic and physicochemical risk factors for calcium oxalate kidney stone formation in a small group of healthy subjects.
International urology and nephrology.
2019 Jul; 51(7):1121-1127. doi:
10.1007/s11255-019-02186-2. [PMID: 31161522] - Lianghua Shen, Sijia Lei, Luyuan Huang, Shuaiguang Li, Shanze Yi, Mason Breitzig, Meiyan Huang, Xuemei Mo, Hanxiao Sun, Qing Zheng, Jianing Tian, Alexander Czachor, Feng Wang. Therapeutic effects of the rhSOD2-Hirudin fusion protein on bleomycin-induced pulmonary fibrosis in mice.
European journal of pharmacology.
2019 Jun; 852(?):77-89. doi:
10.1016/j.ejphar.2019.03.001. [PMID: 30831079] - Ningning Zhang, Tristen Wright, Xiaoting Wang, Uddhab Karki, Brett J Savary, Jianfeng Xu. Engineering 'designer' glycomodules for boosting recombinant protein secretion in tobacco hairy root culture and studying hydroxyproline-O-glycosylation process in plants.
Plant biotechnology journal.
2019 06; 17(6):1130-1141. doi:
10.1111/pbi.13043. [PMID: 30467956] - Hyun-Jun Lee, Hye-Lim Jang, Dong-Kyu Ahn, Hun-Jung Kim, Hee Young Jeon, Dae Bang Seo, Ji-Hae Lee, Jin Kyu Choi, Seok-Seong Kang. Orally administered collagen peptide protects against UVB-induced skin aging through the absorption of dipeptide forms, Gly-Pro and Pro-Hyp.
Bioscience, biotechnology, and biochemistry.
2019 Jun; 83(6):1146-1156. doi:
10.1080/09168451.2019.1580559. [PMID: 30739561]