N-Acetyl-L-alanine (BioDeep_00000400068)

Main id: BioDeep_00000017901

Secondary id: BioDeep_00000229625, BioDeep_00000405916, BioDeep_00000603978

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


N-Acetyl-L-alanine

化学式: C5H9NO3 (131.0582404)
中文名称: N-乙酰-L-丙氨酸
谱图信息: 最多检出来源 Homo sapiens(feces) 0.11%

分子结构信息

SMILES: CC(C(=O)O)NC(=O)C
InChI: InChI=1S/C5H9NO3/c1-3(5(8)9)6-4(2)7/h3H,1-2H3,(H,6,7)(H,8,9)/t3-/m0/s1

描述信息

An N-acetyl-L-amino acid that is L-alanine in which one of the hydrogens attached to the nitrogen is replaced by an acetyl group.
C26170 - Protective Agent > C275 - Antioxidant
Ac-Ala-OH is an endogenous metabolite.

同义名列表

3 个代谢物同义名

N-Acetyl-L-alanine; Ac-Ala-OH; N-Acetyl-L-alanine



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Soshi Takahashi, Jun Saegusa, Akira Onishi, Akio Morinobu. Biomarkers identified by serum metabolomic analysis to predict biologic treatment response in rheumatoid arthritis patients. Rheumatology (Oxford, England). 2019 12; 58(12):2153-2161. doi: 10.1093/rheumatology/kez199. [PMID: 31143951]
  • Charles A Lewis, Richard Wolfenden. Amide bonds to the nitrogen atoms of cysteine and serine as 'weak points' in the backbones of proteins. Biochemistry. 2011 Aug; 50(33):7259-64. doi: 10.1021/bi200813s. [PMID: 21755938]
  • Wen Qing Li, Hamid Yaqoob Qureshi, Abdelhamid Liacini, Faramaze Dehnade, Muhammad Zafarullah. Transforming growth factor Beta1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species. Free radical biology & medicine. 2004 Jul; 37(2):196-207. doi: 10.1016/j.freeradbiomed.2004.04.028. [PMID: 15203191]
  • Magnus Stödeman, Frederick P Schwarz. Importance of product inhibition in the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry. Analytical biochemistry. 2002 Sep; 308(2):285-93. doi: 10.1016/s0003-2697(02)00339-1. [PMID: 12419341]
  • Gary O Rankin, Suk K Hong, Dianne K Anestis, Travis T Henderson, John G Ball, Monica A Valentovic, Patrick I Brown. Effect of three n-acetylamino acids on N-(3,5-dichlorophenyl)succinimide (NDPS) and ndps metabolite nephrotoxicity in Fischer 344 rats. Journal of toxicology and environmental health. Part A. 2002 Apr; 65(7):539-56. doi: 10.1080/15287390252807993. [PMID: 11939711]
  • X Qiu, H J Forman, A H Schönthal, E Cadenas. Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells. The Journal of biological chemistry. 1996 Dec; 271(50):31915-21. doi: 10.1074/jbc.271.50.31915. [PMID: 8943236]
  • W W Karakawa, J A Kane. Immunochemical analysis of a Smith-like antigen isolated from two human strains of Staphylococcus aureus. Journal of immunology (Baltimore, Md. : 1950). 1975 Aug; 115(2):564-8. doi: NULL. [PMID: 50368]