Lauroylcarnitine (BioDeep_00000399946)

   

natural product PANOMIX_OTCML-2023


代谢物信息卡片


(3R)-3-(dodecanoyloxy)-4-(trimethylazaniumyl)butanoate

化学式: C19H37NO4 (343.27224420000005)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 0.92%

分子结构信息

SMILES: CCCCCCCCCCCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C
InChI: InChI=1S/C19H37NO4/c1-5-6-7-8-9-10-11-12-13-14-19(23)24-17(15-18(21)22)16-20(2,3)4/h17H,5-16H2,1-4H3/t17-/m1/s1

描述信息

Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.
Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

同义名列表

9 个代谢物同义名

(3R)-3-(dodecanoyloxy)-4-(trimethylazaniumyl)butanoate; L-Carnitine dodecanoyl ester; (R)-Dodecanoylcarnitine; Dodecanoyl-L-carnitine; Lauroyl-L(-)-carnitin; (-)-Lauroylcarnitine; Dodecanoylcarnitine; Lauroyl-L-carnitine; Lauroylcarnitine



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hulya Turk, Serkan Erdal, Rahmi Dumlupinar. Exogenous carnitine application augments transport of fatty acids into mitochondria and stimulates mitochondrial respiration in maize seedlings grown under normal and cold conditions. Cryobiology. 2019 12; 91(?):97-103. doi: 10.1016/j.cryobiol.2019.10.003. [PMID: 31589831]
  • Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
  • Jan-Willem Schoonen, Vincent van Duinen, Amar Oedit, Paul Vulto, Thomas Hankemeier, Petrus W Lindenburg. Continuous-flow microelectroextraction for enrichment of low abundant compounds. Analytical chemistry. 2014 Aug; 86(16):8048-56. doi: 10.1021/ac500707v. [PMID: 24892382]
  • Brante P Sampey, Alex J Freemerman, Jimmy Zhang, Pei-Fen Kuan, Joseph A Galanko, Thomas M O'Connell, Olga R Ilkayeva, Michael J Muehlbauer, Robert D Stevens, Christopher B Newgard, Heather A Brauer, Melissa A Troester, Liza Makowski. Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. PloS one. 2012; 7(6):e38812. doi: 10.1371/journal.pone.0038812. [PMID: 22701716]
  • Nobuyuki Doi, Mikio Tomita, Masahiro Hayashi. Absorption enhancement effect of acylcarnitines through changes in tight junction protein in Caco-2 cell monolayers. Drug metabolism and pharmacokinetics. 2011; 26(2):162-70. doi: 10.2133/dmpk.dmpk-10-rg-071. [PMID: 21206134]
  • Klaus Eder, Juliane Felgner, Karin Becker, Holger Kluge. Free and total carnitine concentrations in pig plasma after oral ingestion of various L-carnitine compounds. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 2005 Jan; 75(1):3-9. doi: 10.1024/0300-9831.75.1.3. [PMID: 15830915]
  • Christine Dufes, Jean-Christophe Olivier, Frédéric Gaillard, Afsaneh Gaillard, William Couet, Jean-Marc Muller. Brain delivery of vasoactive intestinal peptide (VIP) following nasal administration to rats. International journal of pharmaceutics. 2003 Apr; 255(1-2):87-97. doi: 10.1016/s0378-5173(03)00039-5. [PMID: 12672605]
  • S Kagatani, T Shinoda, M Fukui, T Ohmura, S Hasumi, T Sonobe. Enhancement of nasal salmon calcitonin absorption by lauroylcarnitine chloride in rats. Pharmaceutical research. 1996 May; 13(5):739-43. doi: 10.1023/a:1016051600828. [PMID: 8860430]
  • C D McCallum, R M Epand. Insulin receptor autophosphorylation and signaling is altered by modulation of membrane physical properties. Biochemistry. 1995 Feb; 34(6):1815-24. doi: 10.1021/bi00006a001. [PMID: 7849042]