Reichsteins Substance S (BioDeep_00000399338)
natural product
代谢物信息卡片
Reichsteins Substance S
化学式: C21H30O4 (346.214398)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(natural_products) 85.71%
分子结构信息
SMILES: CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C(=O)CO)O)C
InChI: InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:125417
- PubChem: 227112
- ChEMBL: CHEMBL1705958
- MeSH: Cortodoxone
- CAS: 37-60-5
- MoNA: CCMSLIB00000079060
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kandaswamy Kalaivani, Sengottayan Senthil-Nathan, Vethamonickam Stanley-Raja, Prabhakaran Vasantha-Srinivasan. Physiological and biochemical alterations in Vigna rdiate L. triggered by sesame derived elicitors as defense mechanism against Rhizoctonia and Macrophomina infestation.
Scientific reports.
2023 08; 13(1):13884. doi:
10.1038/s41598-023-39660-y. [PMID: 37620354] - Hannah Peterson, Leon Kircik, April W Armstrong. Individual Article: Clascoterone Cream 1\%: Mechanism of Action, Efficacy, and Safety of a Novel, First-in-Class Topical Antiandrogen Therapy for Acne.
Journal of drugs in dermatology : JDD.
2023 Jun; 22(6):SF350992s7-SF350992s14. doi:
. [PMID: 37276168] - Yu Song, Luting Nie, Dandan Wei, Pengling Liu, Keliang Fan, Li Zhang, Mian Wang, Lulu Wang, Wei Liao, Ning Kang, Qingqing Xu, Juan Wang, Zhenxing Mao, Chongjian Wang, Wenqian Huo. Serum cortisol-to-cortisone ratio and 11-deoxycortisol are associated with hypertension and blood pressure in Chinese rural population: a cross sectional study.
Journal of hypertension.
2022 03; 40(3):432-440. doi:
10.1097/hjh.0000000000003028. [PMID: 34670995] - Parvathy Santhosh, Mamatha George. Clascoterone: a new topical anti-androgen for acne management.
International journal of dermatology.
2021 Dec; 60(12):1561-1565. doi:
10.1111/ijd.15752. [PMID: 34242398] - Silvia M Albillos, Olimpio Montero, Sara Calvo, Berta Solano-Vila, José M Trejo, Esther Cubo. Plasma acyl-carnitines, bilirubin, tyramine and tetrahydro-21-deoxycortisol in Parkinson's disease and essential tremor. A case control biomarker study.
Parkinsonism & related disorders.
2021 10; 91(?):167-172. doi:
10.1016/j.parkreldis.2021.09.014. [PMID: 34649109] - Flávia A Costa-Barbosa, Valdemir M Carvalho, Kelly C Oliveira, José Gilberto H Vieira, Claudio E Kater. Reassessment of predictive values of ACTH-stimulated serum 21-deoxycortisol and 17-hydroxyprogesterone to identify CYP21A2 heterozygote carriers and nonclassic subjects.
Clinical endocrinology.
2021 10; 95(4):677-685. doi:
10.1111/cen.14550. [PMID: 34231242] - Ciaran A Shaughnessy, Stephen D McCormick. 11-Deoxycortisol is a stress responsive and gluconeogenic hormone in a jawless vertebrate, the sea lamprey (Petromyzon marinus).
The Journal of experimental biology.
2021 06; 224(11):. doi:
10.1242/jeb.241943. [PMID: 34086050] - Simon Travers, Claire Bouvattier, Jérôme Fagart, Laetitia Martinerie, Say Viengchareun, Eric Pussard, Marc Lombès. Interaction between accumulated 21-deoxysteroids and mineralocorticoid signaling in 21-hydroxylase deficiency.
American journal of physiology. Endocrinology and metabolism.
2020 02; 318(2):E102-E110. doi:
10.1152/ajpendo.00368.2019. [PMID: 31821037] - L I Velikanova, Z R Shafigullina, N V Vorokhobina, E V Malevanaya. Gas Chromatography-Mass Spectrometry Analysis of Urinary Steroid Metabolomics for Detection of Early Signs of Adrenal Neoplasm Malignancy in Patients with Cushing's Syndrome.
Bulletin of experimental biology and medicine.
2019 Sep; 167(5):676-680. doi:
10.1007/s10517-019-04597-8. [PMID: 31630306] - Alessandro Mazzetti, Luigi Moro, Mara Gerloni, Martina Cartwright. Pharmacokinetic Profile, Safety, and Tolerability of Clascoterone (Cortexolone 17-alpha propionate, CB-03-01) Topical Cream, 1\% in Subjects With Acne Vulgaris: An Open-Label Phase 2a Study.
Journal of drugs in dermatology : JDD.
2019 Jun; 18(6):563. doi:
. [PMID: 31251549] - Xiao Yang, Zhenru Wang, Qian Zhang, Ran Liu, Huarong Xu, Kaishun Bi, Qing Li. The internal link of serum steroid hormones levels in insomnia, depression, and Alzheimer's disease rats: Is there an effective way to distinguish among these three diseases based on potential biomarkers?.
Journal of separation science.
2019 May; 42(10):1833-1841. doi:
10.1002/jssc.201801298. [PMID: 30848087] - Caridad Rosette, Frances J. Agan, Alessandro Mazzetti, Luigi Moro, Mara Gerloni. Cortexolone 17α-propionate (Clascoterone) Is a Novel Androgen Receptor Antagonist that Inhibits Production of Lipids and Inflammatory Cytokines from Sebocytes In Vitro.
Journal of drugs in dermatology : JDD.
2019 May; 18(5):412-418. doi:
". [PMID: 31141847] - Xue Liu, Jingjing Jiang, Xiaotian Liu, Zhicheng Luo, Yan Wang, Xiaokang Dong, Dandan Wei, Wenqian Huo, Songcheng Yu, Linlin Li, Shuna Jin, Chongjian Wang, Zhenxing Mao. Gender-Specific Independent and Combined Effects of the Cortisol-to-Cortisone Ratio and 11-Deoxycortisol on Prediabetes and Type 2 Diabetes Mellitus: From the Henan Rural Cohort Study.
Journal of diabetes research.
2019; 2019(?):4693817. doi:
10.1155/2019/4693817. [PMID: 31281850] - Joanne Sloan-Lancaster, Eyas Raddad, Amy Flynt, Yan Jin, James Voelker, Jeffrey W Miller. LY3045697: Results from two randomized clinical trials of a novel inhibitor of aldosterone synthase.
Journal of the renin-angiotensin-aldosterone system : JRAAS.
2017 Jul; 18(3):1470320317717883. doi:
10.1177/1470320317717883. [PMID: 28814143] - Christopher M Jones, Ashwini Mallappa, Nicole Reisch, Nikolaos Nikolaou, Nils Krone, Beverly A Hughes, Donna M O'Neil, Martin J Whitaker, Jeremy W Tomlinson, Karl-Heinz Storbeck, Deborah P Merke, Richard J Ross, Wiebke Arlt. Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia.
The Journal of clinical endocrinology and metabolism.
2017 06; 102(6):1797-1806. doi:
10.1210/jc.2016-2855. [PMID: 27845856] - Alexander M Clifford, Nicolas R Bury, Aaron G Schultz, James D Ede, Brendan L Goss, Greg G Goss. Regulation of plasma glucose and sulfate excretion in Pacific hagfish, Eptatretus stoutii is not mediated by 11-deoxycortisol.
General and comparative endocrinology.
2017 06; 247(?):107-115. doi:
10.1016/j.ygcen.2017.01.022. [PMID: 28126345] - D H Abbott, B H Rayome, D A Dumesic, K C Lewis, A K Edwards, K Wallen, M E Wilson, S E Appt, J E Levine. Clustering of PCOS-like traits in naturally hyperandrogenic female rhesus monkeys.
Human reproduction (Oxford, England).
2017 04; 32(4):923-936. doi:
10.1093/humrep/dex036. [PMID: 28333238] - Manuela Nickler, Manuel Ottiger, Christian Steuer, Alexander Kutz, Mirjam Christ-Crain, Werner Zimmerli, Robert Thomann, Claus Hoess, Christoph Henzen, Luca Bernasconi, Andreas Huber, Beat Mueller, Philipp Schuetz. Time-dependent association of glucocorticoids with adverse outcome in community-acquired pneumonia: a 6-year prospective cohort study.
Critical care (London, England).
2017 03; 21(1):72. doi:
10.1186/s13054-017-1656-7. [PMID: 28335807] - L I Velikanova, Z R Shafigullina, A A Lisitsin, N V Vorokhobina, K Grigoryan, E A Kukhianidze, E G Strelnikova, N S Krivokhizhina, L M Krasnov, E A Fedorov, I V Sablin, A L Moskvin, E A Bessonova. Different Types of Urinary Steroid Profiling Obtained by High-Performance Liquid Chromatography and Gas Chromatography-Mass Spectrometry in Patients with Adrenocortical Carcinoma.
Hormones & cancer.
2016 12; 7(5-6):327-335. doi:
10.1007/s12672-016-0267-0. [PMID: 27370636] - A E Kulle, F G Riepe, J Hedderich, W G Sippell, J Schmitz, L Niermeyer, P M Holterhus. LC-MS/MS based determination of basal- and ACTH-stimulated plasma concentrations of 11 steroid hormones: implications for detecting heterozygote CYP21A2 mutation carriers.
European journal of endocrinology.
2015 Oct; 173(4):517-24. doi:
10.1530/eje-14-1084. [PMID: 26315375] - T M A Kerkhofs, M N Kerstens, I P Kema, T P Willems, H R Haak. Diagnostic Value of Urinary Steroid Profiling in the Evaluation of Adrenal Tumors.
Hormones & cancer.
2015 Aug; 6(4):168-75. doi:
10.1007/s12672-015-0224-3. [PMID: 25985881] - Satbir Rai, András Szeitz, Brent W Roberts, Quill Christie, Wesley Didier, Junho Eom, Sang-Seon Yun, David A Close. A putative corticosteroid hormone in Pacific lamprey, Entosphenus tridentatus.
General and comparative endocrinology.
2015 Feb; 212(?):178-84. doi:
10.1016/j.ygcen.2014.06.019. [PMID: 24971804] - Diane Dufour-Rainfray, Valérie Moal, Lucie Cloix, Elisabeth Mathieu, Anne-Sophie Gauchez, Julie Brossaud, Jean-Benoît Corcuff, François Fraissinet, Christine Collet, Florence Boux de Casson, Denis Guilloteau, Patrick Emond, Pascal Reynier. [Mass spectrometry for steroid assays].
Annales de biologie clinique.
2015 Jan; 73(1):70-8. doi:
10.1684/abc.2014.0988. [PMID: 25582724] - Julie A Ray, Mark M Kushnir, Richard A Yost, Alan L Rockwood, A Wayne Meikle. Performance enhancement in the measurement of 5 endogenous steroids by LC-MS/MS combined with differential ion mobility spectrometry.
Clinica chimica acta; international journal of clinical chemistry.
2015 Jan; 438(?):330-6. doi:
10.1016/j.cca.2014.07.036. [PMID: 25110813] - Clemens Kamrath, Michaela F Hartmann, Claudia Boettcher, Stefan A Wudy. Reduced activity of 11β-hydroxylase accounts for elevated 17α-hydroxyprogesterone in preterms.
The Journal of pediatrics.
2014 Aug; 165(2):280-4. doi:
10.1016/j.jpeds.2014.04.011. [PMID: 24862381] - Wenxian Tan, Joseph Aizen, Peter Thomas. Membrane progestin receptor alpha mediates progestin-induced sperm hypermotility and increased fertilization success in southern flounder (Paralichthys lethostigma).
General and comparative endocrinology.
2014 May; 200(?):18-26. doi:
10.1016/j.ygcen.2014.02.003. [PMID: 24530629] - Brent W Roberts, Wes Didier, Satbir Rai, Nicholas S Johnson, Scot Libants, Sang-Seon Yun, David A Close. Regulation of a putative corticosteroid, 17,21-dihydroxypregn-4-ene,3,20-one, in sea lamprey, Petromyzon marinus.
General and comparative endocrinology.
2014 Jan; 196(?):17-25. doi:
10.1016/j.ygcen.2013.11.008. [PMID: 24287339] - Ryuji Kouyama, Kiichiro Hiraishi, Toru Sugiyama, Hajime Izumiyama, Takanobu Yoshimoto, Takumi Akashi, Kazunori Kihara, Keiko Homma, Hirotaka Shibata, Yukio Hirata. Clinicopathological features, biochemical and molecular markers in 5 patients with adrenocortical carcinoma.
Endocrine journal.
2011; 58(7):527-34. doi:
10.1507/endocrj.k11e-026. [PMID: 21521927] - Gwen E Dressing, Yefei Pang, Jing Dong, Peter Thomas. Progestin signaling through mPRα in Atlantic croaker granulosa/theca cell cocultures and its involvement in progestin inhibition of apoptosis.
Endocrinology.
2010 Dec; 151(12):5916-26. doi:
10.1210/en.2010-0165. [PMID: 20962051] - Flávia A Costa-Barbosa, Vânia F Tonetto-Fernandes, Valdemir M Carvalho, Odete H Nakamura, Vivian Moura, Tânia A S S Bachega, José G H Vieira, Claudio E Kater. Superior discriminating value of ACTH-stimulated serum 21-deoxycortisol in identifying heterozygote carriers for 21-hydroxylase deficiency.
Clinical endocrinology.
2010 Dec; 73(6):700-6. doi:
10.1111/j.1365-2265.2010.03871.x. [PMID: 20846292] - Brett C McWhinney, Scott E Briscoe, Jacobus P J Ungerer, Carel J Pretorius. Measurement of cortisol, cortisone, prednisolone, dexamethasone and 11-deoxycortisol with ultra high performance liquid chromatography-tandem mass spectrometry: Application for plasma, plasma ultrafiltrate, urine and saliva in a routine laboratory.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Oct; 878(28):2863-9. doi:
10.1016/j.jchromb.2010.08.044. [PMID: 20851063] - David A Close, Sang-Seon Yun, Stephen D McCormick, Andrew J Wildbill, Weiming Li. 11-deoxycortisol is a corticosteroid hormone in the lamprey.
Proceedings of the National Academy of Sciences of the United States of America.
2010 Aug; 107(31):13942-7. doi:
10.1073/pnas.0914026107. [PMID: 20643930] - Kazuhito Mizuki. [Urinary tetrahydro-11-deoxycortisol].
Nihon rinsho. Japanese journal of clinical medicine.
2010 Jul; 68 Suppl 7(?):401-3. doi:
NULL. [PMID: 20960803] - Päivi Nykänen, Kirsti Heinonen, Felix G Riepe, Wolfgang G Sippell, Raimo Voutilainen. Serum concentrations of adrenal steroids and their precursors as a measure of maturity of adrenocortical function in very premature newborns.
Hormone research in paediatrics.
2010; 74(5):358-64. doi:
10.1159/000314970. [PMID: 20606393] - Julie Brossaud, Pascal Barat, Dominique Gualde, Jean-Benoît Corcuff. Cross reactions elicited by serum 17-OH progesterone and 11-desoxycortisol in cortisol assays.
Clinica chimica acta; international journal of clinical chemistry.
2009 Sep; 407(1-2):72-4. doi:
10.1016/j.cca.2009.05.019. [PMID: 19481537] - Peter Thomas, Md Saydur Rahman. Chronic hypoxia impairs gamete maturation in Atlantic croaker induced by progestins through nongenomic mechanisms resulting in reduced reproductive success.
Environmental science & technology.
2009 Jun; 43(11):4175-80. doi:
10.1021/es9000399. [PMID: 19569348] - Noura Meklat, Jean-Claude Tabet, Jacques de Ceaurriz. Urine ratio of tetrahydrocortisol to tetrahydrodeoxycortisol to screen for the systemic administration of cortisone and hydrocortisone.
Forensic science international.
2009 Mar; 185(1-3):e13-7. doi:
10.1016/j.forsciint.2008.12.011. [PMID: 19185436] - Vânia Tonetto-Fernandes, Sofia H V Lemos-Marini, Maricilda P De Mello, Luciane M Ribeiro-Neto, Claudio E Kater. 21-hydroxylase deficiency transiently mimicking combined 21- and 11beta-hydroxylase deficiency.
Journal of pediatric endocrinology & metabolism : JPEM.
2008 May; 21(5):487-94. doi:
10.1515/jpem.2008.21.5.487. [PMID: 18655532] - Héctor F Escobar-Morreale, Raul Sanchón, José L San Millán. A prospective study of the prevalence of nonclassical congenital adrenal hyperplasia among women presenting with hyperandrogenic symptoms and signs.
The Journal of clinical endocrinology and metabolism.
2008 Feb; 93(2):527-33. doi:
10.1210/jc.2007-2053. [PMID: 18000084] - Yuichi Kaji, Takahiro Hiraoka, Fumiki Okamoto, Hiroki Asano, Tetsuro Oshika. Comparison of triamcinolone acetonide, 11-deoxycortisol and other lipid formulae for the visualization of vitreous body in the anterior chamber after posterior capsule rupture in animal models.
Acta ophthalmologica.
2008 Feb; 86(1):97-102. doi:
10.1111/j.1600-0420.2007.01058.x. [PMID: 17908254] - Christian Otte, Maryann Lenoci, Thomas Metzler, Rachel Yehuda, Charles R Marmar, Thomas C Neylan. Effects of metyrapone on hypothalamic-pituitary-adrenal axis and sleep in women with post-traumatic stress disorder.
Biological psychiatry.
2007 Apr; 61(8):952-6. doi:
10.1016/j.biopsych.2006.08.018. [PMID: 17336940] - Helen Imrie, Marie Freel, Bongani M Mayosi, Eleanor Davies, Robert Fraser, Mary Ingram, Heather J Cordell, Martin Farrall, Peter J Avery, Hugh Watkins, Bernard Keavney, John M C Connell. Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.
The Journal of clinical endocrinology and metabolism.
2006 Dec; 91(12):5051-6. doi:
10.1210/jc.2006-1481. [PMID: 16984984] - Mark M Kushnir, Alan L Rockwood, William L Roberts, Elizabeth G Pattison, William E Owen, Ashley M Bunker, A Wayne Meikle. Development and performance evaluation of a tandem mass spectrometry assay for 4 adrenal steroids.
Clinical chemistry.
2006 Aug; 52(8):1559-67. doi:
10.1373/clinchem.2006.068445. [PMID: 16777916] - N S Sieber-Ruckstuhl, F S Boretti, M Wenger, C Maser-Gluth, C E Reusch. Cortisol, aldosterone, cortisol precursor, androgen and endogenous ACTH concentrations in dogs with pituitary-dependant hyperadrenocorticism treated with trilostane.
Domestic animal endocrinology.
2006 Jul; 31(1):63-75. doi:
10.1016/j.domaniend.2005.09.004. [PMID: 16233969] - Vania Tonetto-Fernandes, Sofia H V Lemos-Marini, Hilton Kuperman, Luciane M Ribeiro-Neto, Ieda T N Verreschi, Claudio E Kater. Serum 21-Deoxycortisol, 17-Hydroxyprogesterone, and 11-deoxycortisol in classic congenital adrenal hyperplasia: clinical and hormonal correlations and identification of patients with 11beta-hydroxylase deficiency among a large group with alleged 21-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism.
2006 Jun; 91(6):2179-84. doi:
10.1210/jc.2005-1890. [PMID: 16551734] - Polyxeni Koutkia, Jacqueline Berry, Kristina Eaton, Jeff Breu, Steven Grinspoon. Increased adrenal androgen secretion with inhibition of 11beta-hydroxylase in HIV-infected women.
American journal of physiology. Endocrinology and metabolism.
2006 May; 290(5):E808-13. doi:
10.1152/ajpendo.00418.2005. [PMID: 16303845] - K Müssig, S Kaltenbach, C Maser-Gluth, M F Hartmann, S A Wudy, M Horger, B Gallwitz, F Raue, H-U Häring, E Schulze. Late diagnosis of congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
2006 Apr; 114(4):208-14. doi:
10.1055/s-2006-924072. [PMID: 16705555] - Norihiro Kobayashi, Keiichi Iwakami, Shuhei Kotoshiba, Toshifumi Niwa, Yoshinori Kato, Nariyasu Mano, Junichi Goto. Immunoenzymometric assay for a small molecule,11-deoxycortisol, with attomole-range sensitivity employing an scFv-enzyme fusion protein and anti-idiotype antibodies.
Analytical chemistry.
2006 Apr; 78(7):2244-53. doi:
10.1021/ac051858f. [PMID: 16579604] - M Hoshiro, Y Ohno, H Masaki, H Iwase, N Aoki. Comprehensive study of urinary cortisol metabolites in hyperthyroid and hypothyroid patients.
Clinical endocrinology.
2006 Jan; 64(1):37-45. doi:
10.1111/j.1365-2265.2005.02412.x. [PMID: 16402926] - E Endert, A Ouwehand, E Fliers, M F Prummel, W M Wiersinga. Establishment of reference values for endocrine tests. Part IV: Adrenal insufficiency.
The Netherlands journal of medicine.
2005 Dec; 63(11):435-43. doi:
. [PMID: 16397312] - Marieke den Brinker, Koen F M Joosten, Olivia Liem, Frank H de Jong, Wim C J Hop, Jan A Hazelzet, Marije van Dijk, Anita C S Hokken-Koelega. Adrenal insufficiency in meningococcal sepsis: bioavailable cortisol levels and impact of interleukin-6 levels and intubation with etomidate on adrenal function and mortality.
The Journal of clinical endocrinology and metabolism.
2005 Sep; 90(9):5110-7. doi:
10.1210/jc.2005-1107. [PMID: 15985474] - Kazuhito Mizuki, Toshihiko Yanase, Hajime Nawata. [Urinary tetrahydro-11-deoxycortisol (THS)].
Nihon rinsho. Japanese journal of clinical medicine.
2005 Aug; 63 Suppl 8(?):373-5. doi:
NULL. [PMID: 16149532] - Bryon Adinoff, Steven R Krebaum, Patricia A Chandler, Wen Ye, Morton B Brown, Mark J Williams. Dissection of hypothalamic-pituitary-adrenal axis pathology in 1-month-abstinent alcohol-dependent men, part 1: adrenocortical and pituitary glucocorticoid responsiveness.
Alcoholism, clinical and experimental research.
2005 Apr; 29(4):517-27. doi:
10.1097/01.alc.0000158940.05529.0a. [PMID: 15834216] - Nicola Glorioso, Fabiana Filigheddu, Paolo Pinna Parpaglia, Aldo Soro, Chiara Troffa, Giuseppe Argiolas, Paolo Mulatero. 11beta-Hydroxysteroid dehydrogenase type 2 activity is associated with left ventricular mass in essential hypertension.
European heart journal.
2005 Mar; 26(5):498-504. doi:
10.1093/eurheartj/ehi070. [PMID: 15618035] - Wen-Shiun Yueh, Peter Thomas, Ching-Fong Chang. Identification of 17,20beta,21-trihydroxy-4-pregnen-3-one as an oocyte maturation-inducing steroid in black porgy, Acanthopagrus schlegeli.
General and comparative endocrinology.
2005 Feb; 140(3):184-91. doi:
10.1016/j.ygcen.2004.10.014. [PMID: 15639146] - Bernard Keavney, Bongani Mayosi, Nicole Gaukrodger, Helen Imrie, Michelle Baker, Robert Fraser, Mary Ingram, Hugh Watkins, Martin Farrall, Eleanor Davies, John Connell. Genetic variation at the locus encompassing 11-beta hydroxylase and aldosterone synthase accounts for heritability in cortisol precursor (11-deoxycortisol) urinary metabolite excretion.
The Journal of clinical endocrinology and metabolism.
2005 Feb; 90(2):1072-7. doi:
10.1210/jc.2004-0870. [PMID: 15522937] - L I Velikanova. [Specific features of diagnosis of hormonal insufficiency in patients with tumors of the adrenal cortex].
Vestnik khirurgii imeni I. I. Grekova.
2005; 164(3):43-5. doi:
. [PMID: 16281397] - A Sturm, N Bury, L Dengreville, J Fagart, G Flouriot, M E Rafestin-Oblin, P Prunet. 11-deoxycorticosterone is a potent agonist of the rainbow trout (Oncorhynchus mykiss) mineralocorticoid receptor.
Endocrinology.
2005 Jan; 146(1):47-55. doi:
10.1210/en.2004-0128. [PMID: 15486226] - Michael Kellner, Mildred Schick, Alexander Yassouridis, Tobias Struttmann, Klaus Wiedemann, Barbara Alm. Metyrapone tests in patients with panic disorder.
Biological psychiatry.
2004 Dec; 56(11):898-900. doi:
10.1016/j.biopsych.2004.08.005. [PMID: 15576069] - Holger Jahn, Mildred Schick, Falk Kiefer, Michael Kellner, Alexander Yassouridis, Klaus Wiedemann. Metyrapone as additive treatment in major depression: a double-blind and placebo-controlled trial.
Archives of general psychiatry.
2004 Dec; 61(12):1235-44. doi:
10.1001/archpsyc.61.12.1235. [PMID: 15583115] - P W Sorensen, C A Murphy, K Loomis, P Maniak, P Thomas. Evidence that 4-pregnen-17,20beta,21-triol-3-one functions as a maturation-inducing hormone and pheromonal precursor in the percid fish, Gymnocephalus cernuus.
General and comparative endocrinology.
2004 Oct; 139(1):1-11. doi:
10.1016/j.ygcen.2004.05.014. [PMID: 15474530] - K E Warnes, I C McMillen, J S Robinson, C L Coulter. Differential actions of metyrapone on the fetal pituitary-adrenal axis in the sheep fetus in late gestation.
Biology of reproduction.
2004 Aug; 71(2):620-8. doi:
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