Tetracaine hydrochloride (BioDeep_00000399088)
natural product
代谢物信息卡片
Tetracaine hydrochloride (Pontocaine)
化学式: C15H25ClN2O2 (300.160446)
中文名称: 盐酸丁卡因
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(=C(C=CC(=C1)C(OCCN(C)C)=O)NCCCC).Cl
InChI: 1H
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:9469
- KEGGdrug: D00741
- PubChem: 8695
- ChEMBL: CHEMBL1255654
- MeSH: Tetracaine
- CAS: 53762-93-9
- CAS: 136-47-0
- MoNA: CCMSLIB00000078514
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- R Pérez-Isidoro, F J Guevara-Pantoja, C Ventura-Hunter, C Guerrero-Sánchez, J C Ruiz-Suárez, U S Schubert, E Saldívar-Guerra. Fluidized or not fluidized? Biophysical characterization of biohybrid lipid/protein/polymer liposomes and their interaction with tetracaine.
Biochimica et biophysica acta. General subjects.
2023 02; 1867(2):130287. doi:
10.1016/j.bbagen.2022.130287. [PMID: 36460234] - Simone R Castro, Lígia N M Ribeiro, Márcia C Breitkreitz, Viviane A Guilherme, Gustavo H Rodrigues da Silva, Hery Mitsutake, Ana C S Alcântara, Fabiano Yokaichiya, Margareth K K D Franco, Daniel Clemens, Ben Kent, Marcelo Lancellotti, Daniele R de Araújo, Eneida de Paula. A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers.
Scientific reports.
2021 11; 11(1):21463. doi:
10.1038/s41598-021-99743-6. [PMID: 34728779] - Robin Wijngaard, Marina Parra-Robert, Lourdes Marés, Anna Escalante, Emilio Salgado, Bernardino González-de-la-Presa, Jordi To-Figueras, Mercè Brunet. Tetracaine from urethral ointment causes false positive amphetamine results by immunoassay.
Clinical toxicology (Philadelphia, Pa.).
2021 06; 59(6):500-505. doi:
10.1080/15563650.2020.1834114. [PMID: 33112680] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - W Q Liu, R Bai, C L Ma, F Yu, B Xie, M Dong, J Ha, D Wen. Metabolomics Changes of Serum and Tissues in Mice Died of Acute Tetracaine Poisoning.
Fa yi xue za zhi.
2021 Apr; 37(2):166-174. doi:
10.12116/j.issn.1004-5619.2020.401006. [PMID: 34142476] - Carol S Velez-Saboyá, Eric Oropeza-Guzman, Francisco J Sierra-Valdez, Jesús C Ruiz-Suárez. Ca2+-mediated enhancement of anesthetic diffusion across phospholipid multilamellar systems.
Biochimica et biophysica acta. Biomembranes.
2021 02; 1863(2):183509. doi:
10.1016/j.bbamem.2020.183509. [PMID: 33189718] - Shipeng Hu, Tao Zhao, Hewen Li, Danling Cheng, Zhihua Sun. Effect of tetracaine on dynamic reorganization of lipid membranes.
Biochimica et biophysica acta. Biomembranes.
2020 09; 1862(9):183351. doi:
10.1016/j.bbamem.2020.183351. [PMID: 32416192] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Mahmud Arif Pavel, Hae-Won Chung, E Nicholas Petersen, Scott B Hansen. Polymodal Mechanism for TWIK-Related K+ Channel Inhibition by Local Anesthetic.
Anesthesia and analgesia.
2019 10; 129(4):973-982. doi:
10.1213/ane.0000000000004216. [PMID: 31124840] - Xiaoli Liu, Qianqian Zhao. Long-term anesthetic analgesic effects: Comparison of tetracaine loaded polymeric nanoparticles, solid lipid nanoparticles, and nanostructured lipid carriers in vitro and in vivo.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Sep; 117(?):109057. doi:
10.1016/j.biopha.2019.109057. [PMID: 31203133] - Zhiyi Yu, David C Chiara, Pavel Y Savechenkov, Karol S Bruzik, Jonathan B Cohen. A photoreactive analog of allopregnanolone enables identification of steroid-binding sites in a nicotinic acetylcholine receptor.
The Journal of biological chemistry.
2019 05; 294(19):7892-7903. doi:
10.1074/jbc.ra118.007172. [PMID: 30923128] - Zhan Song, Ting-Jun Fan. Tetracaine induces apoptosis through a mitochondrion-dependent pathway in human corneal stromal cells in vitro.
Cutaneous and ocular toxicology.
2018 Dec; 37(4):350-358. doi:
10.1080/15569527.2018.1468342. [PMID: 29742927] - Svetlana S Efimova, Evgeny G Chulkov, Olga S Ostroumova. Lipid-mediated mode of action of local anesthetics on lipid pores induced by polyenes, peptides and lipopeptides.
Colloids and surfaces. B, Biointerfaces.
2018 Jun; 166(?):1-8. doi:
10.1016/j.colsurfb.2018.02.051. [PMID: 29525621] - Seifollah Jalili, Marzieh Saeedi. Study of procaine and tetracaine in the lipid bilayer using molecular dynamics simulation.
European biophysics journal : EBJ.
2017 Apr; 46(3):265-282. doi:
10.1007/s00249-016-1164-8. [PMID: 27557558] - Anthony T Cacek, Jogarao V S Gobburu, Mathangi Gopalakrishnan. Population Pharmacokinetics of an Intranasally Administered Combination of Oxymetazoline and Tetracaine in Healthy Volunteers.
Journal of clinical pharmacology.
2017 02; 57(2):247-254. doi:
10.1002/jcph.799. [PMID: 27436060] - Dan Liu, Jingdong Peng, Shaopu Liu, Mingqiong Zhou, Jing Zhang, Aiping Li. Resonance Rayleigh scattering technique as a detection method for the RP-HPLC determination of local anaesthetics in human urine.
Luminescence : the journal of biological and chemical luminescence.
2017 Feb; 32(1):4-10. doi:
10.1002/bio.3140. [PMID: 27145989] - Rosendo Pérez-Isidoro, J C Ruiz-Suárez. Calcium and protons affect the interaction of neurotransmitters and anesthetics with anionic lipid membranes.
Biochimica et biophysica acta.
2016 09; 1858(9):2215-2222. doi:
10.1016/j.bbamem.2016.06.017. [PMID: 27362370] - Qinqin Xu, Tao Zhao, Zhihua Sun. Monitoring drug-lipid membrane interactions via a molecular rotor probe.
The Analyst.
2016 Aug; 141(15):4676-84. doi:
10.1039/c6an00721j. [PMID: 27243370] - Anikó Lajtai, Mátyás Mayer, Ágnes Lakatos, Zoltán Porpáczy, Attila Miseta. Embutramide, a Component of Tanax(®) (T-61) as a New Drug of Abuse?.
Journal of forensic sciences.
2016 Mar; 61(2):573-575. doi:
10.1111/1556-4029.13010. [PMID: 27404634] - María del Mar LópezGuerrero, Maykel Hernández-Mesa, Carmen Cruces-Blanco, Ana M García-Campaña. On-line preconcentration strategy for the simultaneous quantification of three local anesthetics in human urine using CZE.
Electrophoresis.
2015 Dec; 36(23):2961-7. doi:
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2015 Jun; 93(?):205-13. doi:
10.1016/j.ejpb.2015.02.024. [PMID: 25748796] - Raquel S Teixeira, Tânia F G G Cova, Sérgio M C Silva, Rita Oliveira, Maria J Araújo, Eduardo F Marques, Alberto A C C Pais, Francisco J B Veiga. Lysine-based surfactants as chemical permeation enhancers for dermal delivery of local anesthetics.
International journal of pharmaceutics.
2014 Oct; 474(1-2):212-22. doi:
10.1016/j.ijpharm.2014.08.002. [PMID: 25108047] - Lotta Salmela, Clive Washington. A continuous flow method for estimation of drug release rates from emulsion formulations.
International journal of pharmaceutics.
2014 Sep; 472(1-2):276-81. doi:
10.1016/j.ijpharm.2014.06.024. [PMID: 24945139] - Patricio A Zapata-Morin, F J Sierra-Valdez, J C Ruiz-Suárez. The interaction of local anesthetics with lipid membranes.
Journal of molecular graphics & modelling.
2014 Sep; 53(?):200-205. doi:
10.1016/j.jmgm.2014.08.001. [PMID: 25181454] - A P Serro, R Galante, A Kozica, P Paradiso, A M P S Gonçalves da Silva, K V Luzyanin, A C Fernandes, B Saramago. Effect of tetracaine on DMPC and DMPC+cholesterol biomembrane models: liposomes and monolayers.
Colloids and surfaces. B, Biointerfaces.
2014 Apr; 116(?):63-71. doi:
10.1016/j.colsurfb.2013.12.042. [PMID: 24448175] - Alicia R Sanderson, Edward C Wu, Lih-Huei L Liaw, Rohit Garg, Richard A Gangnes. The effect of topical anesthetic hydration on the depth of thermal injury from the plasma skin regeneration device.
Lasers in surgery and medicine.
2014 Feb; 46(2):127-31. doi:
10.1002/lsm.22210. [PMID: 24375476] - Da Huang, Tao Zhao, Wei Xu, Tinglu Yang, Paul S Cremer. Sensing small molecule interactions with lipid membranes by local pH modulation.
Analytical chemistry.
2013 Nov; 85(21):10240-8. doi:
10.1021/ac401955t. [PMID: 24152205] - Joel L Cohen. Pain management with a topical lidocaine and tetracaine 7\%/7\% cream with laser dermatologic procedures.
Journal of drugs in dermatology : JDD.
2013 Sep; 12(9):986-9. doi:
. [PMID: 24002144] - Georgette Oni, Yvonne Rasko, Jeffrey Kenkel. Topical lidocaine enhanced by laser pretreatment: a safe and effective method of analgesia for facial rejuvenation.
Aesthetic surgery journal.
2013 Aug; 33(6):854-61. doi:
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Journal of analytical toxicology.
2013 Apr; 37(3):186. doi:
10.1093/jat/bks140. [PMID: 23358154] - Cátia Bandeiras, Ana Paula Serro, Konstantin Luzyanin, Anabela Fernandes, Benilde Saramago. Anesthetics interacting with lipid rafts.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2013 Jan; 48(1-2):153-65. doi:
10.1016/j.ejps.2012.10.023. [PMID: 23142844] - Francisco J Sierra-Valdez, Linda S Forero-Quintero, Patricio A Zapata-Morin, Miguel Costas, Arturo Chavez-Reyes, Jesús C Ruiz-Suárez. The influence of non polar and polar molecules in mouse motile cells membranes and pure lipid bilayers.
PloS one.
2013; 8(4):e59364. doi:
10.1371/journal.pone.0059364. [PMID: 23565149] - Patrick E McCleskey, Seema M Patel, Katherine A Mansalis, Amanda L Elam, Tina R Kinsley. Serum lidocaine levels and cutaneous side effects after application of 23\% lidocaine 7\% tetracaine ointment to the face.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].
2013 Jan; 39(1 Pt 1):82-91. doi:
10.1111/dsu.12064. [PMID: 23278914] - Jarin Paphangkorakit, Chaichan Sangsirinakagul, Aroonsri Priprem. Relief of palatal injection pain by liposome-encapsulated 2\% lignocaine prepared by ultrasonic dental scaler.
The British journal of oral & maxillofacial surgery.
2012 Dec; 50(8):784-7. doi:
10.1016/j.bjoms.2011.12.009. [PMID: 22277697] - Nicole Weizenmann, Daniel Huster, Holger A Scheidt. Interaction of local anesthetics with lipid bilayers investigated by ¹H MAS NMR spectroscopy.
Biochimica et biophysica acta.
2012 Dec; 1818(12):3010-8. doi:
10.1016/j.bbamem.2012.07.014. [PMID: 22842001] - K Ruetzler, B Sima, L Mayer, A Golescu, D Dunkler, W Jaeger, M Hoeferl, J You, D I Sessler, G Grubhofer, D Hutschala. Lidocaine/tetracaine patch (Rapydan) for topical anaesthesia before arterial access: a double-blind, randomized trial.
British journal of anaesthesia.
2012 Nov; 109(5):790-6. doi:
10.1093/bja/aes254. [PMID: 22831890] - Thomas B Marriott, Martha R Charney, Stephanie Stanworth. Effects of application durations and heat on the pharmacokinetic properties of drug delivered by a lidocaine/tetracaine patch: a randomized, open-label, controlled study in healthy volunteers.
Clinical therapeutics.
2012 Oct; 34(10):2174-83. doi:
10.1016/j.clinthera.2012.08.008. [PMID: 22943969] - Helen Giannakopoulos, Lawrence M Levin, Joli C Chou, Anthony T Cacek, Matthew Hutcheson, Stacey A Secreto, Paul A Moore, Elliot V Hersh. The cardiovascular effects and pharmacokinetics of intranasal tetracaine plus oxymetazoline: preliminary findings.
Journal of the American Dental Association (1939).
2012 Aug; 143(8):872-80. doi:
10.14219/jada.archive.2012.0291. [PMID: 22855901] - Norbert Kummerfeld, Marko Legler, Peter Wohlsein, Maren Kummerfeld. [Morphological studies in different avian species on artefacts induced by euthanasia with T 61 " or Pentobarbital (Narcoren)].
Berliner und Munchener tierarztliche Wochenschrift.
2012 Jan; 125(1-2):27-31. doi:
. [PMID: 22372321] - Roberta Aline Franco de Lima, Marcelo Bispo de Jesus, Cíntia Maria Saia Cereda, Giovana Radomille Tofoli, Luis Fernando Cabeça, Irineu Mazzaro, Leonardo Fernandes Fraceto, Eneida de Paula. Improvement of tetracaine antinociceptive effect by inclusion in cyclodextrins.
Journal of drug targeting.
2012 Jan; 20(1):85-96. doi:
10.3109/1061186x.2011.622400. [PMID: 22047178] - Xiaojuan Gan, Shaopu Liu, Zhongfang Liu, Xiaoli Hu. Determination of tetracaine hydrochloride by fluorescence quenching method with some aromatic amino acids as probes.
Journal of fluorescence.
2012 Jan; 22(1):129-35. doi:
10.1007/s10895-011-0938-8. [PMID: 21822580] - Klaara Kannisto, Lasse Murtomäki, Tapani Viitala. An impedance QCM study on the partitioning of bioactive compounds in supported phospholipid bilayers.
Colloids and surfaces. B, Biointerfaces.
2011 Sep; 86(2):298-304. doi:
10.1016/j.colsurfb.2011.04.012. [PMID: 21549577] - Derek R Laver, Dirk F van Helden. Three independent mechanisms contribute to tetracaine inhibition of cardiac calcium release channels.
Journal of molecular and cellular cardiology.
2011 Sep; 51(3):357-69. doi:
10.1016/j.yjmcc.2011.05.009. [PMID: 21624373] - Trang T Nguyen, John C Conboy. High-throughput screening of drug-lipid membrane interactions via counter-propagating second harmonic generation imaging.
Analytical chemistry.
2011 Aug; 83(15):5979-88. doi:
10.1021/ac2009614. [PMID: 21696170] - Adriana L Andrade, Kenneth Melich, G Gregory Whatley, Sarah R Kirk, Jeffrey W Karpen. Cyclic nucleotide-gated channel block by hydrolysis-resistant tetracaine derivatives.
Journal of medicinal chemistry.
2011 Jul; 54(13):4904-12. doi:
10.1021/jm200495g. [PMID: 21634421] - Katrin M Kirschbaum, Wolfgang Grellner, Gertrud Rochholz, Frank Musshoff, Burkhard Madea. Liquid chromatography-tandem mass spectrometry detection of the quaternary ammonium compound mebezonium as an active ingredient in t61.
Journal of analytical toxicology.
2011 Mar; 35(2):124-8. doi:
10.1093/anatox/35.2.124. [PMID: 21396233] - Minghua Lu, Qin Li, Yongquan Lai, Lan Zhang, Bin Qiu, Guonan Chen, Zongwei Cai. Determination of stimulants and narcotics as well as their in vitro metabolites by online CE-ESI-MS.
Electrophoresis.
2011 Feb; 32(3-4):472-8. doi:
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Clinical toxicology (Philadelphia, Pa.).
2010 Aug; 48(7):725-9. doi:
10.3109/15563650.2010.498790. [PMID: 20849330] - Wei-Wei Qin, Zheng Jiao, Ming-Kang Zhong, Xiao-Jin Shi, Jun Zhang, Zhong-Dong Li, Xue-Yan Cui. Simultaneous determination of procaine, lidocaine, ropivacaine, tetracaine and bupivacaine in human plasma by high-performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 May; 878(15-16):1185-9. doi:
10.1016/j.jchromb.2010.03.003. [PMID: 20356808] - Fredrick A Hilliard, Derek S Steele, Derek Laver, Zhaokang Yang, Sylvain J Le Marchand, Nagesh Chopra, David W Piston, Sabine Huke, Björn C Knollmann. Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.
Journal of molecular and cellular cardiology.
2010 Feb; 48(2):293-301. doi:
10.1016/j.yjmcc.2009.10.005. [PMID: 19835880] - Richard T Addo, Aladin Siddig, Rodney Siwale, Neil J Patel, Janet Akande, Akm N Uddin, Martin J D'Souza. Formulation, characterization and testing of tetracaine hydrochloride-loaded albumin-chitosan microparticles for ocular drug delivery.
Journal of microencapsulation.
2010; 27(2):95-104. doi:
10.3109/02652040903010638. [PMID: 20055748] - Hanwen Sun, Ming Su, Liqing Li. Simultaneous determination of tetracaine, proline, and enoxacin in human urine by CE with ECL detection.
Journal of chromatographic science.
2010 Jan; 48(1):49-54. doi:
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Colloids and surfaces. B, Biointerfaces.
2009 Aug; 72(1):135-40. doi:
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2009 Jan; 71(5):2063-8. doi:
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Nature.
2008 Apr; 452(7190):1012-6. doi:
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Molecular pharmacology.
2008 Mar; 73(3):880-90. doi:
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Guang pu xue yu guang pu fen xi = Guang pu.
2008 Feb; 28(2):389-93. doi:
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Cell calcium.
2008 Feb; 43(2):142-54. doi:
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International journal of dermatology.
2008 Jan; 47(1):87-90. doi:
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American journal of physiology. Heart and circulatory physiology.
2007 Oct; 293(4):H2448-61. doi:
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Biophysical journal.
2007 Jun; 92(11):3988-4001. doi:
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Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2007; 10(3):288-98. doi:
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Colloids and surfaces. B, Biointerfaces.
2006 Mar; 48(1):58-66. doi:
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Neurobiology of aging.
2006 Feb; 27(2):262-9. doi:
10.1016/j.neurobiolaging.2005.01.001. [PMID: 16399211] - Ming Ma, Shaoying Kang, Qian Zhao, Bo Chen, Shouzhuo Yao. Liquid-phase microextraction combined with high-performance liquid chromatography for the determination of local anaesthetics in human urine.
Journal of pharmaceutical and biomedical analysis.
2006 Jan; 40(1):128-35. doi:
10.1016/j.jpba.2005.06.023. [PMID: 16076540] - Amelie Lupp, Elke Karge, Johannes Wange, Claudia Eisentraut, Tobias Zwenizner, Herbert Oelschläger, Christian Fleck. In vitro interactions with the Cytochrome P450 system, toxicity, and local anaesthetic effects of Fomocaine Alkylmorpholine derivatives in rats.
Arzneimittel-Forschung.
2006; 56(1):1-11. doi:
10.1055/s-0031-1296694. [PMID: 16477999] - Tomoyuki Araki, Yukifumi Uesono, Tomoko Oguchi, Akio Toh-E. LAS24/KOG1, a component of the TOR complex 1 (TORC1), is needed for resistance to local anesthetic tetracaine and normal distribution of actin cytoskeleton in yeast.
Genes & genetic systems.
2005 Oct; 80(5):325-43. doi:
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Bulletin of experimental biology and medicine.
2005 Sep; 140(3):315-6. doi:
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Biochemical and biophysical research communications.
2005 Aug; 334(1):140-4. doi:
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Colloids and surfaces. B, Biointerfaces.
2005 May; 42(3-4):197-203. doi:
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Journal of molecular biology.
2004 Oct; 343(1):199-212. doi:
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American journal of physiology. Renal physiology.
2004 Jan; 286(1):F111-9. doi:
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Biochemistry.
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American journal of nephrology.
2003 May; 23(3):129-39. doi:
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Biochimica et biophysica acta.
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Anesthesia and analgesia.
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Journal of pharmacological and toxicological methods.
2001 Nov; 46(3):131-6. doi:
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Blood cells, molecules & diseases.
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Acta physiologica Scandinavica.
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Anesthesia and analgesia.
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The Journal of physiology.
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Anesthesiology.
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Arzneimittel-Forschung.
1999 Mar; 49(3):281-5. doi:
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Clinical hemorheology and microcirculation.
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Cell calcium.
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Archives of biochemistry and biophysics.
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Die Pharmazie.
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British journal of haematology.
1997 Dec; 99(4):959-67. doi:
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Regional anesthesia.
1997 Jul; 22(4):325-31. doi:
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