Avobenzone (BioDeep_00000398992)
natural product
代谢物信息卡片
Avobenzone (Parsol 1789)
化学式: C20H22O3 (310.15688620000003)
中文名称: 1-(4-叔丁基苯基)-3-(4-甲氧基苯基)-1,3-丙二酮
谱图信息:
最多检出来源 Helianthus annuus(natural_products) 66.67%
分子结构信息
SMILES: C1=C(C=CC(=C1)C(CC(C2=CC=C(C=C2)C(C)(C)C)=O)=O)OC
InChI: InChI=1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3
描述信息
D020011 - Protective Agents > D011837 - Radiation-Protective Agents > D013473 - Sunscreening Agents
C1892 - Chemopreventive Agent > C851 - Sunscreen
D003879 - Dermatologic Agents
D003358 - Cosmetics
同义名列表
2 个代谢物同义名
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:134751
- KEGGdrug: D03015
- PubChem: 51040
- Metlin: METLIN3932
- DrugBank: DB09495
- ChEMBL: CHEMBL1200522
- CAS: 23644-60-2
- CAS: 87075-14-7
- CAS: 70356-09-1
- MoNA: CCMSLIB00000077204
- MoNA: CCMSLIB00000078337
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Nageswara R Pilli, Suresh Narayanasamy, Jeffry Florian, Robbert Zusterzeel, Vikram Patel, David G Strauss, Murali K Matta. Novel simultaneous method for the determination of avobenzone and oxybenzone in human plasma by UHPLC-MS/MS with phospholipid removal pretreatment: An application to a sunscreen clinical trial.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2021 Apr; 1169(?):122615. doi:
10.1016/j.jchromb.2021.122615. [PMID: 33706185] - Jeayoung C Shin, Eunyoung Lee, Seungchan An, Sun Hee Jin, Jaehyoun Ha, Won Jun Choi, Minsoo Noh. Benzophenone-3 and benzophenone-8 exhibit obesogenic activity via peroxisome proliferator-activated receptor γ pathway.
Toxicology in vitro : an international journal published in association with BIBRA.
2020 Sep; 67(?):104886. doi:
10.1016/j.tiv.2020.104886. [PMID: 32407875] - Xin Zhong, Craig A Downs, Yuting Li, Zishan Zhang, Yiman Li, Binbin Liu, Huiyuan Gao, Qingming Li. Comparison of toxicological effects of oxybenzone, avobenzone, octocrylene, and octinoxate sunscreen ingredients on cucumber plants (Cucumis sativus L.).
The Science of the total environment.
2020 Apr; 714(?):136879. doi:
10.1016/j.scitotenv.2020.136879. [PMID: 32018996] - Murali K Matta, Jeffry Florian, Robbert Zusterzeel, Nageswara R Pilli, Vikram Patel, Donna A Volpe, Yang Yang, Luke Oh, Edward Bashaw, Issam Zineh, Carlos Sanabria, Sarah Kemp, Anthony Godfrey, Steven Adah, Sergio Coelho, Jian Wang, Lesley-Anne Furlong, Charles Ganley, Theresa Michele, David G Strauss. Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
JAMA.
2020 01; 323(3):256-267. doi:
10.1001/jama.2019.20747. [PMID: 31961417] - Julia Hiller, Katrin Klotz, Sebastian Meyer, Wolfgang Uter, Kerstin Hof, Annette Greiner, Thomas Göen, Hans Drexler. Systemic availability of lipophilic organic UV filters through dermal sunscreen exposure.
Environment international.
2019 11; 132(?):105068. doi:
10.1016/j.envint.2019.105068. [PMID: 31470219] - Katrin Klotz, Kerstin Hof, Julia Hiller, Thomas Göen, Hans Drexler. Quantification of prominent organic UV filters and their metabolites in human urine and plasma samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Sep; 1125(?):121706. doi:
10.1016/j.jchromb.2019.06.033. [PMID: 31302475] - Sungjin Ahn, Seungchan An, Moonyoung Lee, Eunyoung Lee, Jeong Joo Pyo, Jeong Hyeon Kim, Min Won Ki, Sun Hee Jin, Jaehyoun Ha, Minsoo Noh. A long-wave UVA filter avobenzone induces obesogenic phenotypes in normal human epidermal keratinocytes and mesenchymal stem cells.
Archives of toxicology.
2019 07; 93(7):1903-1915. doi:
10.1007/s00204-019-02462-1. [PMID: 31016361] - Murali K Matta, Robbert Zusterzeel, Nageswara R Pilli, Vikram Patel, Donna A Volpe, Jeffry Florian, Luke Oh, Edward Bashaw, Issam Zineh, Carlos Sanabria, Sarah Kemp, Anthony Godfrey, Steven Adah, Sergio Coelho, Jian Wang, Lesley-Anne Furlong, Charles Ganley, Theresa Michele, David G Strauss. Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
JAMA.
2019 06; 321(21):2082-2091. doi:
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2018 Jun; 17(3):518-522. doi:
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Ecotoxicology and environmental safety.
2017 Jul; 141(?):178-187. doi:
10.1016/j.ecoenv.2017.03.034. [PMID: 28343007] - Shigenobu Yoshida, Syuntaro Hiradate, Motoo Koitabashi, Tsunashi Kamo, Seiya Tsushima. Phyllosphere Methylobacterium bacteria contain UVA-absorbing compounds.
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2015 Oct; 1003(?):41-6. doi:
10.1016/j.jchromb.2015.09.014. [PMID: 26409261] - Valentina Trotta, Filipa Goios, Helena Monteiro, Isabel F Almeida, Santo Scalia. Influence of lipid microparticle encapsulation on in vitro efficacy, photostability and water resistance of the sunscreen agents, octyl methoxycinnamate and butyl methoxydibenzoylmethane.
Drug development and industrial pharmacy.
2014 Sep; 40(9):1233-9. doi:
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Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.
2014 Apr; 13(4):703-16. doi:
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Photochemistry and photobiology.
2013 Sep; 89(5):1085-94. doi:
10.1111/php.12117. [PMID: 23789784] - Jun-Jen Liu, Sami Nazzal, Tzu-Shan Chang, Tsuimin Tsai. Preparation and characterization of cosmeceutical liposomes loaded with avobenzone and arbutin.
Journal of cosmetic science.
2013 Jan; 64(1):9-17. doi:
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Nanotechnology.
2012 Aug; 23(31):315704. doi:
10.1088/0957-4484/23/31/315704. [PMID: 22797534] - Woan-Ruoh Lee, Shing-Chuan Shen, Saleh A Al-Suwayeh, Yi-Ching Li, Jia-You Fang. Erbium:YAG laser resurfacing increases skin permeability and the risk of excessive absorption of antibiotics and sunscreens: the influence of skin recovery on drug absorption.
Toxicology letters.
2012 Jun; 211(2):150-8. doi:
10.1016/j.toxlet.2012.03.797. [PMID: 22483991] - Rachel Haywood, Arsen Volkov, Carima Andrady, Robert Sayer. Measuring sunscreen protection against solar-simulated radiation-induced structural radical damage to skin using ESR/spin trapping: development of an ex vivo test method.
Free radical research.
2012 Mar; 46(3):265-75. doi:
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2011 Sep; 10(9):1474-9. doi:
10.1039/c1pp05072a. [PMID: 21547313] - L Montenegro, M G Sarpietro, S Ottimo, G Puglisi, F Castelli. Differential scanning calorimetry studies on sunscreen loaded solid lipid nanoparticles prepared by the phase inversion temperature method.
International journal of pharmaceutics.
2011 Aug; 415(1-2):301-6. doi:
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2011 Jul; 5(10):164-73. doi:
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2011 Jul; 9(4):247-50. doi:
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2011 Jan; 54(2):345-50. doi:
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Skin pharmacology and physiology.
2011; 24(4):182-9. doi:
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2009 Aug; 98(8):2759-69. doi:
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