Amorolfine hydrochloride (BioDeep_00000398946)
natural product
代谢物信息卡片
化学式: C21H36ClNO (353.24852760000005)
中文名称: 盐酸阿莫洛芬
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(=C(C=CC(=C1)CC(CN2C[C@@H](O[C@@H](C2)C)C)C)C(CC)(C)C).Cl
InChI: 1H/t16?,17-,18+
描述信息
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C254 - Anti-Infective Agent > C514 - Antifungal Agent
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:59649
- KEGGdrug: D01720
- PubChem: 54259
- ChEMBL: CHEMBL4303363
- CAS: 78613-38-4
- MoNA: CCMSLIB00000078236
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Paulo H F Carmo, Gustavo J C Freitas, João C M Dornelas, Bruna C T Almeida, Ludmila M Baltazar, Gabriella F Ferreira, Nalu T A Peres, Daniel A Santos. Reactive oxygen and nitrogen species are crucial for the antifungal activity of amorolfine and ciclopirox olamine against the dermatophyte Trichophyton interdigitale.
Medical mycology.
2022 Aug; 60(8):. doi:
10.1093/mmy/myac058. [PMID: 35896502] - Sumanas Bunyaratavej, Varalak Srinonprasert, Rungsima Kiratiwongwan, Supisara Wongdama, Charussri Leeyaphan. Onychomycosis in older adults: The age and associated factors affecting the complete cure rate.
The Australasian journal of dermatology.
2022 Feb; 63(1):74-80. doi:
10.1111/ajd.13686. [PMID: 34398469] - Lara Baccarin Ianiski, Paula Cristina Stibbe, Laura Bedin Denardi, Carla Weiblen, Mauro Pereira Soares, Julia de Souza Silveira Valente, Luís Antônio Sangioni, Daniela Isabel Brayer Pereira, Janio Morais Santurio, Sônia de Avila Botton. In vitro anti-Pythium insidiosum activity of amorolfine hydrochloride and azithromycin, alone and in combination.
Medical mycology.
2021 Jan; 59(1):67-73. doi:
10.1093/mmy/myaa032. [PMID: 32400872] - T Auvinen, R Tiihonen, M Soini, M Wangel, A Sipponen, J J Jokinen. Efficacy of topical resin lacquer, amorolfine and oral terbinafine for treating toenail onychomycosis: a prospective, randomized, controlled, investigator-blinded, parallel-group clinical trial.
The British journal of dermatology.
2015 Oct; 173(4):940-8. doi:
10.1111/bjd.13934. [PMID: 26036329] - G Roncari, C Ponelle, R Zumbrunnen, A Guenzi, J Dingemanse, J H Jonkman. Percutaneous absorption of amorolfine following a single topical application of an amorolfine cream formulation.
Clinical and experimental dermatology.
1992 Sep; 17 Suppl 1(?):33-6. doi:
10.1111/j.1365-2230.1992.tb00275.x. [PMID: 1458662] - D Reinel. Topical treatment of onychomycosis with amorolfine 5\% nail lacquer: comparative efficacy and tolerability of once and twice weekly use.
Dermatology (Basel, Switzerland).
1992; 184 Suppl 1(?):21-4. doi:
10.1159/000247612. [PMID: 1532336] - T Hiratani, Y Asagi, A Matsusaka, K Uchida, H Yamaguchi. [In vitro antifungal activity of amorolfine, a new morpholine antimycotic agent].
The Japanese journal of antibiotics.
1991 Sep; 44(9):993-1006. doi:
. [PMID: 1960861] - A Polak-Wyss, H Lengsfeld, G Oesterhelt. Effect of oxiconazole and Ro 14-4767/002 on sterol pattern in Candida albicans.
Sabouraudia.
1985 Dec; 23(6):433-41. doi:
10.1080/00362178585380631. [PMID: 3913013]