Doripenem hydrate (BioDeep_00000398880)
natural product
代谢物信息卡片
Doripenem hydrate
化学式: C15H26N4O7S2 (438.1242846)
中文名称: 多尼培南(一水合物)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1([C@]([C@]2(N1C(=C([C@H]2C)S[C@@H]3CN[C@@H](C3)CNS(N)(=O)=O)C(=O)O)[H])([C@H](C)O)[H])=O.O
InChI: /m1./s1
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:31518
- KEGGdrug: D01836
- PubChem: 636377
- ChEMBL: CHEMBL4303454
- CAS: 364622-82-2
- CAS: 364622-82-2, 148016-81-3 (free base)
- MoNA: CCMSLIB00000078119
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Makoto Kai, Ryota Tanaka, Yosuke Suzuki, Koji Goto, Yoshifumi Ohchi, Norihisa Yasuda, Ryosuke Tatsuta, Takaaki Kitano, Hiroki Itoh. Simultaneous quantification of plasma levels of 12 antimicrobial agents including carbapenem, anti-methicillin-resistant Staphylococcus aureus agent, quinolone and azole used in intensive care unit using UHPLC-MS/MS method.
Clinical biochemistry.
2021 Apr; 90(?):40-49. doi:
10.1016/j.clinbiochem.2021.01.012. [PMID: 33539809] - Ko Nonoshita, Yosuke Suzuki, Ryota Tanaka, Tetsuya Kaneko, Yoshifumi Ohchi, Yuhki Sato, Norihisa Yasuda, Koji Goto, Takaaki Kitano, Hiroki Itoh. Population pharmacokinetic analysis of doripenem for Japanese patients in intensive care unit.
Scientific reports.
2020 12; 10(1):22148. doi:
10.1038/s41598-020-79076-6. [PMID: 33335198] - Astrid Broeker, Matthias G Vossen, Florian Thalhammer, Steven C Wallis, Jeffrey Lipman, Jason A Roberts, Sebastian G Wicha. An Integrated Dialysis Pharmacometric (IDP) Model to Evaluate the Pharmacokinetics in Patients Undergoing Renal Replacement Therapy.
Pharmaceutical research.
2020 May; 37(6):96. doi:
10.1007/s11095-020-02832-w. [PMID: 32409892] - Yumiko Matsuo, Sayaka Matsumoto, Toshihiro Wajima, Kazuo Matsubara. Pharmacokinetic modeling and simulation for dose rationale of doripenem in neonates and infants.
Drug metabolism and pharmacokinetics.
2020 Feb; 35(1):145-150. doi:
10.1016/j.dmpk.2019.10.003. [PMID: 31969257] - Toshihisa Hiraiwa, Kazuhiro Moriyama, Kana Matsumoto, Yasuyo Shimomura, Yu Kato, Chizuru Yamashita, Yoshitaka Hara, Takahiro Kawaji, Yasuyoshi Kurimoto, Tomoyuki Nakamura, Naohide Kuriyama, Junpei Shibata, Hidefumi Komura, Kunihiko Morita, Osamu Nishida. In vitro Evaluation of Linezolid and Doripenem Clearance with Different Hemofilters.
Blood purification.
2020; 49(3):295-301. doi:
10.1159/000504039. [PMID: 31995801] - Yumiko Matsuo, Toru Ishibashi, Sayaka Matsumoto, Takayuki Katsube, Toshihiro Wajima. Population Pharmacokinetics of Doripenem in Pediatric Patients and Monte-Carlo Pharmacokinetic-Pharmacodynamic Simulations for Dosing Regimen Assessment.
Journal of pharmaceutical sciences.
2019 09; 108(9):3099-3105. doi:
10.1016/j.xphs.2019.04.002. [PMID: 30974120] - Weerachai Chaijamorn, Punyawee Puchsaka, Sutthiporn Pattharachayakul, Taniya Charoensareerat, Nattachai Srisawat, Apinya Boonpeng, Chalermsri Pummangura. Doripenem dosing regimens in Asian critically ill patients with continuous renal replacement therapy.
Journal of critical care.
2019 08; 52(?):233-236. doi:
10.1016/j.jcrc.2019.04.030. [PMID: 31108327] - Naohito Ide, Seitaro Sato, Kazuyo Sawaguchi. [Risk of Acute Kidney Injury in Patients Treated with Vancomycin and Piperacillin/Tazobactam Compared to Vancomycin and Meropenem or Doripenem: A Retrospective Cohort Study].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2019; 139(12):1609-1614. doi:
10.1248/yakushi.19-00137. [PMID: 31787651] - So Won Kim, Sangmin Choe, Dong Jin Kim, Dae Young Zang, Dong-Hwan Lee. Pharmacokinetics of Doripenem in Healthy Koreans and Monte Carlo Simulations to Explore Optimal Dosage Regimens in Patients With Normal and Enhanced Renal Function.
Therapeutic drug monitoring.
2018 08; 40(4):425-434. doi:
10.1097/ftd.0000000000000528. [PMID: 29746394] - Lubna Maryam, Ashima Sharma, Mohd W Azam, Shahper N Khan, Asad U Khan. Understanding the mode of binding mechanism of doripenem to human serum albumin: Spectroscopic and molecular docking approaches.
Journal of molecular recognition : JMR.
2018 07; 31(7):e2710. doi:
10.1002/jmr.2710. [PMID: 29603446] - M G Vossen, L Ehmann, S Pferschy, A Maier-Salamon, M Haidinger, C Weiser, J M Wenisch, K Saria, C Kajahn, S Jilch, R Lemmerer, M Bécède, M Zeitlinger, C Kloft, W Jäger, F Thalhammer. Elimination of Doripenem during Dialysis and Pharmacokinetic Evaluation of Posthemodialysis Dosing for Patients Undergoing Intermittent Renal Replacement Therapy.
Antimicrobial agents and chemotherapy.
2018 05; 62(5):. doi:
10.1128/aac.02430-17. [PMID: 29530855] - Zoe Oesterreicher, Iris Minichmayr, Robert Sauermann, Daniela Marhofer, Edith Lackner, Walter Jäger, Alexandra Maier-Salamon, Richard Schwameis, Charlotte Kloft, Markus Zeitlinger. Pharmacokinetics of doripenem in plasma and epithelial lining fluid (ELF): comparison of two dosage regimens.
European journal of clinical pharmacology.
2017 Dec; 73(12):1609-1613. doi:
10.1007/s00228-017-2327-y. [PMID: 28920154] - Eun Kyoung Chung, Megan R Fleming, S Christian Cheatham, Michael B Kays. Population Pharmacokinetics and Pharmacodynamics of Doripenem in Obese, Hospitalized Patients.
The Annals of pharmacotherapy.
2017 Mar; 51(3):209-218. doi:
10.1177/1060028016676831. [PMID: 28168884] - Nuggehally R Srinivas. Interspecies scaling of excretory amounts using allometry - retrospective analysis with rifapentine, aztreonam, carumonam, pefloxacin, miloxacin, trovafloxacin, doripenem, imipenem, cefozopran, ceftazidime, linezolid for urinary excretion and rifapentine, cabotegravir, and dolutegravir for fecal excretion.
Xenobiotica; the fate of foreign compounds in biological systems.
2016 Sep; 46(9):784-92. doi:
10.3109/00498254.2015.1121554. [PMID: 26711252] - Yi-Fan Hu, Chang-Pan Liu, Nai-Yu Wang, Shou-Chuan Shih. In vitro antibacterial activity of rifampicin in combination with imipenem, meropenem and doripenem against multidrug-resistant clinical isolates of Pseudomonas aeruginosa.
BMC infectious diseases.
2016 08; 16(1):444. doi:
10.1186/s12879-016-1785-7. [PMID: 27553962] - M G Vossen, J M Wenisch, A Maier-Salamon, A Fritsch, K Saria, C Zuba, S Jilch, R Lemmerer, M Unger, U Jaehde, W Jäger, F Thalhammer. Doripenem Treatment during Continuous Renal Replacement Therapy.
Antimicrobial agents and chemotherapy.
2015 Dec; 60(3):1687-94. doi:
10.1128/aac.01801-15. [PMID: 26711775] - Kiran Shekar, Jason A Roberts, Adrian G Barnett, Sara Diab, Steven C Wallis, Yoke L Fung, John F Fraser. Can physicochemical properties of antimicrobials be used to predict their pharmacokinetics during extracorporeal membrane oxygenation? Illustrative data from ovine models.
Critical care (London, England).
2015 Dec; 19(?):437. doi:
10.1186/s13054-015-1151-y. [PMID: 26667471] - Yinfang Zhu, Shunli Ji, Shaohui Li, Cheng Li, Feifang Zhang, Xinmiao Liang. [Analysis of carbapenems by hydrophilic interaction chromatography and its application].
Se pu = Chinese journal of chromatography.
2015 Sep; 33(9):946-50. doi:
10.3724/sp.j.1123.2015.05005. [PMID: 26753282] - Iolanda Cirillo, Nicole Vaccaro, Bibiana Castaneda-Ruiz, Rebecca Redman, Veerle Cossey, John S Bradley, Karel Allegaert. Open-Label Study To Evaluate the Single-Dose Pharmacokinetics, Safety, and Tolerability of Doripenem in Infants Less than 12 Weeks in Chronological Age.
Antimicrobial agents and chemotherapy.
2015 Aug; 59(8):4742-9. doi:
10.1128/aac.00485-15. [PMID: 26014957] - Noriyuki Ishihara, Nobuhiro Nishimura, Hiroki Tamaki, Fumi Karino, Kiyotaka Miura, Takeshi Isobe, Kazuro Ikawa, Norifumi Morikawa, Kohji Naora. Evaluation of a pharmacokineticpharmacodynamic approach using software to optimize the carbapenem antibiotic regimen.
International journal of clinical pharmacology and therapeutics.
2015 Jun; 53(6):422-9. doi:
10.5414/cp202191. [PMID: 25828635] - Kadri Tamme, Kersti Oselin, Karin Kipper, Kaywei Low, Joseph F Standing, Tuuli Metsvaht, Juri Karjagin, Koit Herodes, Hartmut Kern, Joel Starkopf. Pharmacokinetics of doripenem during high volume hemodiafiltration in patients with septic shock.
Journal of clinical pharmacology.
2015 Apr; 55(4):438-46. doi:
10.1002/jcph.432. [PMID: 25408310] - Yumiko Matsuo, Toru Ishibashi, Ryuji Kubota, Toshihiro Wajima. Population pharmacokinetics of doripenem in Japanese subjects and Monte-Carlo simulation for patients with renal impairment.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2015 Feb; 21(2):123-9. doi:
10.1016/j.jiac.2014.10.014. [PMID: 25487084] - Wen Liu, Yong-ping Qin, Ying Wang, Jing Zheng, Li Zhang, Shi-qing Shu, Jia Miao. [Pharmacokinetics study of injected doripenemin healthy volunteers].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2015 Jan; 46(1):140-4. doi:
NULL. [PMID: 25807813] - Jason A Roberts, Andrew A Udy, Juergen B Bulitta, Janine Stuart, Paul Jarrett, Therese Starr, Melissa Lassig-Smith, Natasha A Roberts, Rachel Dunlop, Yoshiro Hayashi, Steven C Wallis, Jeffrey Lipman. Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration.
The Journal of antimicrobial chemotherapy.
2014 Sep; 69(9):2508-16. doi:
10.1093/jac/dku177. [PMID: 24879665] - Tatsuya Tada, Tohru Miyoshi-Akiyama, Kayo Shimada, Teruo Kirikae. Biochemical analysis of metallo-β-lactamase NDM-3 from a multidrug-resistant Escherichia coli strain isolated in Japan.
Antimicrobial agents and chemotherapy.
2014 Jun; 58(6):3538-40. doi:
10.1128/aac.02793-13. [PMID: 24687501] - Yu Nobuoka, Akihiro Tanemura, Yoshinori Azumi, Masashi Kishiwada, Ichiro Osawa, Shugo Mizuno, Masanobu Usui, Hiroyuki Sakurai, Masami Tabata, Shuji Isaji. [Studies on the distribution of doripenem in pancreatic tissues, especially on the importance of the ratio in pancreatic tissue concentration of doripenem/serum concentration of doripenem].
The Japanese journal of antibiotics.
2014 Feb; 67(1):15-21. doi:
NULL. [PMID: 24809205] - Andrzej Wieczorek, Andrzej Tokarz, Wojciech Gaszynski, Tomasz Gaszynski. The doripenem serum concentrations in intensive care patients suffering from acute kidney injury, sepsis, and multi organ dysfunction syndrome undergoing continuous renal replacement therapy slow low-efficiency dialysis.
Drug design, development and therapy.
2014; 8(?):2039-44. doi:
10.2147/dddt.s64942. [PMID: 25364230] - Masanori Harada, Naoki Inui, Takafumi Suda, Yutaro Nakamura, Toshihiro Wajima, Yumiko Matsuo, Kingo Chida. Pharmacokinetic analysis of doripenem in elderly patients with nosocomial pneumonia.
International journal of antimicrobial agents.
2013 Aug; 42(2):149-54. doi:
10.1016/j.ijantimicag.2013.03.012. [PMID: 23684002] - Amira A Bhalodi, Rebecca A Keel, Richard Quintiliani, Thomas P Lodise, David P Nicolau, Joseph L Kuti. Pharmacokinetics of doripenem in infected patients treated within and outside the intensive care unit.
The Annals of pharmacotherapy.
2013 May; 47(5):617-27. doi:
10.1345/aph.1r789. [PMID: 23585647] - Iolanda Cirillo, Nicole Vaccaro, Rebecca Redman, Philip L Black, Gregory L Kearns. Pharmacokinetics of single-dose doripenem in adults with cystic fibrosis.
Journal of clinical pharmacology.
2012 Nov; 52(11):1645-53. doi:
10.1177/0091270011427564. [PMID: 22174436] - Gary E Stein, Grace Kulhanek, Curtis L Smith, Joseph L Kuti, David P Nicolau, Amy Scharmen, Chris Farnum, MaryAnn Tran, Apoorv Kalra, Daniel H Havlichek. Pharmacokinetics and monte carlo simulations of doripenem in patients with febrile neutropenia.
The Annals of pharmacotherapy.
2012 Oct; 46(10):1281-6. doi:
10.1345/aph.1r097. [PMID: 23012385] - Haruo Kato, Yasuhiro Shibata, Tomomi Suzuki, Kazuto Ito, Kazuhiro Suzuki. [Septic shock following flexible transurethral lithotripsy showing favourable response after multidisciplinary treatment mainly composed of recombinant thrombomodulin : a case report].
Hinyokika kiyo. Acta urologica Japonica.
2012 Sep; 58(9):499-502. doi:
NULL. [PMID: 23070390] - R Nalda-Molina, A Dokoumetzidis, G Charkoftaki, E Dimaraki, K Margetis, H Archontaki, S Markantonis, N Boutos, D Sakas, E Vryonis, A Skoutelis, G Valsami. Pharmacokinetics of doripenem in CSF of patients with non-inflamed meninges.
The Journal of antimicrobial chemotherapy.
2012 Jul; 67(7):1722-9. doi:
10.1093/jac/dks106. [PMID: 22457313] - Oudy Semoun, Sandrine Marchand, Nicolas Grégoire, Isabelle Lamarche, Christophe Adier, Laurent Laroche, Pablo Goldschmidt, William Couet. Modeling approach to characterize intraocular doripenem pharmacokinetics after intravenous administration to rabbits, with tentative extrapolation to humans.
Antimicrobial agents and chemotherapy.
2012 Jul; 56(7):3531-4. doi:
10.1128/aac.06329-11. [PMID: 22526310] - Andrew A Udy, Jason A Roberts, Jan J De Waele, David L Paterson, Jeffrey Lipman. What's behind the failure of emerging antibiotics in the critically ill? Understanding the impact of altered pharmacokinetics and augmented renal clearance.
International journal of antimicrobial agents.
2012 Jun; 39(6):455-7. doi:
10.1016/j.ijantimicag.2012.02.010. [PMID: 22483562] - Wolfgang Poeppl, Markus Zeitlinger, Oliver Donath, Gabriele Wurm, Markus Müller, Florin Botha, Udo M Illievich, Heinz Burgmann. Penetration of doripenem in human brain: an observational microdialysis study in patients with acute brain injury.
International journal of antimicrobial agents.
2012 Apr; 39(4):343-5. doi:
10.1016/j.ijantimicag.2011.11.019. [PMID: 22325119] - Kogenta Nakamura, Kazuro Ikawa, Yoshiaki Yamada, Maki Arakawa, Kenji Zennami, Genya Nishikawa, Kayo Ikeda, Norifumi Morikawa, Nobuaki Honda. Determination of doripenem penetration into human prostate tissue and assessment of dosing regimens for prostatitis based on site-specific pharmacokinetic-pharmacodynamic evaluation.
Journal of chemotherapy (Florence, Italy).
2012 Feb; 24(1):32-7. doi:
10.1179/1120009x12z.0000000007. [PMID: 22546722] - Bernhard Burian, Markus Zeitlinger, Oliver Donath, Gottfried Reznicek, Robert Sauermann. Penetration of doripenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers.
Antimicrobial agents and chemotherapy.
2012 Jan; 56(1):532-5. doi:
10.1128/aac.05506-11. [PMID: 22083466] - Emily L Heil, Lindsay M Daniels, Christine M Walko, David P Nicolau, Edwin A Smith. Validation of doripenem dosing in patients with end-stage renal disease receiving hemodialysis.
The Annals of pharmacotherapy.
2011 Nov; 45(11):1455-6. doi:
10.1345/aph.1q395. [PMID: 22009996] - Kazutaka Tanoue, Kazuhiko Nishi, Daisuke Kadowaki, Sumio Hirata. Removal of doripenem during hemodialysis and the optimum dosing regimen for patients undergoing hemodialysis.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2011 Jun; 15(3):327-33. doi:
10.1111/j.1744-9987.2011.00914.x. [PMID: 21624085] - Iolanda Cirillo, Nicole Vaccaro, Dainius Balis, Rebecca Redman, Gary R Matzke. Influence of continuous venovenous hemofiltration and continuous venovenous hemodiafiltration on the disposition of doripenem.
Antimicrobial agents and chemotherapy.
2011 Mar; 55(3):1187-93. doi:
10.1128/aac.01063-10. [PMID: 21199922] - Yoshifumi Ohchi, Seigo Hidaka, Koji Goto, Ryo Shitomi, Taichi Nishida, Takakuni Abe, Shunsuke Yamamoto, Norihisa Yasuda, Satoshi Hagiwara, Takayuki Noguchi. Effect of hemopurification rate on doripenem pharmacokinetics in critically ill patients receiving high-flow continuous hemodiafiltration.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2011; 131(9):1395-9. doi:
10.1248/yakushi.131.1395. [PMID: 21881315] - Elias B Chahine, Mary J Ferrill, Mara N Poulakos. Doripenem: a new carbapenem antibiotic.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
2010 Dec; 67(23):2015-24. doi:
10.2146/ajhp090672. [PMID: 21098373] - Cédric Bretonnière, Cédric Jacqueline, Jocelyne Caillon, Christophe Guitton, Virginie Le Mabecque, Anne Françoise Miégeville, Daniel Villers, Gilles Potel, David Boutoille. Efficacy of doripenem in the treatment of Pseudomonas aeruginosa experimental pneumonia versus imipenem and meropenem.
The Journal of antimicrobial chemotherapy.
2010 Nov; 65(11):2423-7. doi:
10.1093/jac/dkq334. [PMID: 20858688] - Partha Nandy, Mahesh N Samtani, Rachel Lin. Population pharmacokinetics of doripenem based on data from phase 1 studies with healthy volunteers and phase 2 and 3 studies with critically ill patients.
Antimicrobial agents and chemotherapy.
2010 Jun; 54(6):2354-9. doi:
10.1128/aac.01649-09. [PMID: 20385854] - Yoshiaki Yamada, Kazuro Ikawa, Kogenta Nakamura, Kenji Mitsui, Masahiro Narushima, Hatsuki Hibi, Kayo Ikeda, Norifumi Morikawa, Nobuaki Honda. Penetration of doripenem into prostatic tissue following intravenous administration in prostatectomy patients.
International journal of antimicrobial agents.
2010 May; 35(5):504-6. doi:
10.1016/j.ijantimicag.2010.01.008. [PMID: 20188521] - Seigo Hidaka, Koji Goto, Satoshi Hagiwara, Hideo Iwasaka, Takayuki Noguchi. Doripenem pharmacokinetics in critically ill patients receiving continuous hemodiafiltration (CHDF).
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2010 Jan; 130(1):87-94. doi:
10.1248/yakushi.130.87. [PMID: 20046071] - Iolanda Cirillo, Nicole Vaccaro, Kenneth Turner, Bhavna Solanki, Jaya Natarajan, Rebecca Redman. Pharmacokinetics, safety, and tolerability of doripenem after 0.5-, 1-, and 4-hour infusions in healthy volunteers.
Journal of clinical pharmacology.
2009 Jul; 49(7):798-806. doi:
10.1177/0091270009337012. [PMID: 19553404] - Florian M E Wagenlehner, Christine Wagenlehner, Rebecca Redman, Wolfgang Weidner, Kurt G Naber. Urinary bactericidal activity of Doripenem versus that of levofloxacin in patients with complicated urinary tract infections or pyelonephritis.
Antimicrobial agents and chemotherapy.
2009 Apr; 53(4):1567-73. doi:
10.1128/aac.01133-08. [PMID: 19188391] - Kazuro Ikawa, Norifumi Morikawa, Shinya Uehara, Koichi Monden, Yoshiaki Yamada, Nobuaki Honda, Hiromi Kumon. Pharmacokinetic-pharmacodynamic target attainment analysis of doripenem in infected patients.
International journal of antimicrobial agents.
2009 Mar; 33(3):276-9. doi:
10.1016/j.ijantimicag.2008.08.031. [PMID: 19095418] - S James Matthews, Jason W Lancaster. Doripenem monohydrate, a broad-spectrum carbapenem antibiotic.
Clinical therapeutics.
2009 Jan; 31(1):42-63. doi:
10.1016/j.clinthera.2009.01.013. [PMID: 19243706] - Kazuro Ikawa, Norifumi Morikawa, Kayo Ikeda, Hiroki Ohge, Taijiro Sueda. Pharmacodynamic assessment of doripenem in peritoneal fluid against Gram-negative organisms: use of population pharmacokinetic modeling and Monte Carlo simulation.
Diagnostic microbiology and infectious disease.
2008 Nov; 62(3):292-7. doi:
10.1016/j.diagmicrobio.2008.06.016. [PMID: 18703305] - Iolanda Cirillo, Geert Mannens, Cor Janssen, Marc Vermeir, Filip Cuyckens, Daksha Desai-Krieger, Nicole Vaccaro, L Mark Kao, Damayanthi Devineni, Rebecca Redman, Kenneth Turner. Disposition, metabolism, and excretion of [14C]doripenem after a single 500-milligram intravenous infusion in healthy men.
Antimicrobial agents and chemotherapy.
2008 Oct; 52(10):3478-83. doi:
10.1128/aac.00424-08. [PMID: 18644951] - Kayo Ikeda, Kazuro Ikawa, Norifumi Morikawa, Keiko Kameda, Nami Urakawa, Hiroki Ohge, Taijiro Sueda. Quantification of doripenem in human plasma and peritoneal fluid by high-performance liquid chromatography with ultraviolet detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2008 May; 867(1):20-5. doi:
10.1016/j.jchromb.2008.03.001. [PMID: 18356120] - Takayuki Katsube, Yoshinori Yamano, Yoshitaka Yano. Pharmacokinetic-pharmacodynamic modeling and simulation for in vivo bactericidal effect in murine infection model.
Journal of pharmaceutical sciences.
2008 Apr; 97(4):1606-14. doi:
10.1002/jps.21062. [PMID: 17705288] - Susan J Keam. Doripenem: a review of its use in the treatment of bacterial infections.
Drugs.
2008; 68(14):2021-57. doi:
10.2165/00003495-200868140-00007. [PMID: 18778123] - Kazuro Ikawa, Norifumi Morikawa, Nami Urakawa, Kayo Ikeda, Hiroki Ohge, Taijiro Sueda. Peritoneal penetration of doripenem after intravenous administration in abdominal-surgery patients.
The Journal of antimicrobial chemotherapy.
2007 Dec; 60(6):1395-7. doi:
10.1093/jac/dkm371. [PMID: 17884833] - Christina Sutherland, David P Nicolau. Development of an HPLC method for the determination of doripenem in human and mouse serum.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Jun; 853(1-2):123-6. doi:
10.1016/j.jchromb.2007.03.004. [PMID: 17392039] - George G Zhanel, Ryan Wiebe, Leanne Dilay, Kristjan Thomson, Ethan Rubinstein, Daryl J Hoban, Ayman M Noreddin, James A Karlowsky. Comparative review of the carbapenems.
Drugs.
2007; 67(7):1027-52. doi:
10.2165/00003495-200767070-00006. [PMID: 17488146] - Toshihiko Hori, Masao Nakano, Yasuo Kimura, Kazuhisa Murakami. Pharmacokinetics and tissue penetration of a new carbapenem, doripenem, intravenously administered to laboratory animals.
In vivo (Athens, Greece).
2006 Jan; 20(1):91-6. doi:
NULL. [PMID: 16433034] - M Tsuji, Y Ishii, A Ohno, S Miyazaki, K Yamaguchi. In vitro and in vivo antibacterial activities of S-4661, a new carbapenem.
Antimicrobial agents and chemotherapy.
1998 Jan; 42(1):94-9. doi:
10.1128/aac.42.1.94. [PMID: 9449267]