thalidomide (BioDeep_00000398833)
Main id: BioDeep_00000002380
natural product Chemicals and Drugs
代谢物信息卡片
thalidomide
化学式: C13H10N2O4 (258.064054)
中文名称: (±)-沙利度胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(N(C(C2C=CC=CC1=2)=O)C3C(NC(CC3)=O)=O)=O
InChI: InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
描述信息
C308 - Immunotherapeutic Agent > C129820 - Antineoplastic Immunomodulating Agent > C157388 - Immunomodulatory Imide Drug
COVID info from Guide to PHARMACOLOGY, clinicaltrial, clinicaltrials, clinical trial, clinical trials
L - Antineoplastic and immunomodulating agents > L04 - Immunosuppressants > L04A - Immunosuppressants
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007917 - Leprostatic Agents
D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents
D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors
D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents
C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant
D006133 - Growth Substances > D006131 - Growth Inhibitors
D009676 - Noxae > D013723 - Teratogens
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
1 个代谢物同义名
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:74947
- ChEBI: CHEBI:9513
- KEGG: C07910
- KEGGdrug: D00754
- PubChem: 5426
- DrugBank: DB01041
- ChEMBL: CHEMBL468
- MeSH: Thalidomide
- CAS: 1012310-87-0
- CAS: 50-35-1
- MoNA: CCMSLIB00000078038
- PubChem: 10112
- NIKKAJI: J4.101G
- RefMet: Thalidomide
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ju Zhang, Yixuan Li, Jing Wang, Huan Jiang, Jiaping Qi, Chen Li, Zhenhua Ying. Is apremilast a treatment for SAPHO syndrome?.
The Journal of dermatological treatment.
2024 Dec; 35(1):2300743. doi:
10.1080/09546634.2023.2300743. [PMID: 38230420] - Yang Yu, Kun Yang. Secondary amenorrhea in a β-thalassemia major patient treated with thalidomide.
Pediatric blood & cancer.
2024 Jun; 71(6):e30982. doi:
10.1002/pbc.30982. [PMID: 38526227] - Maria C Schneeweiss, Denys Shay, Sophia Ly, Richard Wyss, Sebastian Schneeweiss, Robert J Glynn, Arash Mostaghimi. Prevalence of Pretreatment Testing Recommended for Patients With Chronic Inflammatory Skin Diseases.
JAMA dermatology.
2024 Mar; 160(3):334-340. doi:
10.1001/jamadermatol.2023.5895. [PMID: 38294794] - Ya-Ni Huang, Nigel H Greig, Pen-Sen Huang, Yung-Hsiao Chiang, Alan Hoffer, Chih-Hao Yang, David Tweedie, Ying Chen, Ju-Chi Ou, Jia-Yi Wang. Pomalidomide Improves Motor Behavioral Deficits and Protects Cerebral Cortex and Striatum Against Neurodegeneration Through a Reduction of Oxidative/Nitrosative Damages and Neuroinflammation After Traumatic Brain Injury.
Cell transplantation.
2024 Jan; 33(?):9636897241237049. doi:
10.1177/09636897241237049. [PMID: 38483119] - Shujuan Fu, Cunya Li, Zhiying Wang, Zhixian Zhong, Yi Zhong. A case report of thalidomide in the treatment of camrelizumab-induced reactive cutaneous capillary hyperplasia.
Medicine.
2023 Jun; 102(26):e34120. doi:
10.1097/md.0000000000034120. [PMID: 37390264] - Rong-Jing Dong, Jun Li, Yi Zhang, Jia-Sheng Li, Lu-Hui Yang, Yi-Qun Kuang, Rui-Rui Wang, Yu-Ye Li. Thalidomide promotes NLRP3/caspase-1-mediated pyroptosis of macrophages in Talaromyces marneffei infection.
Microbial pathogenesis.
2023 May; ?(?):106168. doi:
10.1016/j.micpath.2023.106168. [PMID: 37224982] - Lin Guo, Yi Liu, Jiansheng Li, Quan Liu, Bing Liu, Xuewen Shi. Inflammatory bowel disease can reduce ovarian reserve function in women: A systematic review and meta-analysis.
Medicine.
2023 Mar; 102(11):e33113. doi:
10.1097/md.0000000000033113. [PMID: 36930072] - Bin Wang, Wanting Qiang, Jia Yi, Shouhong Gao, Bosu Meng, Yuhui Mu, Bolong Wang, Zhipeng Wang, Xia Tao. Simultaneous quantification of thalidomide, lenalidomide and pomadomide in plasma by LC-MS/MS.
Journal of pharmacological and toxicological methods.
2023 Mar; 120(?):107250. doi:
10.1016/j.vascn.2023.107250. [PMID: 36627002] - Hyeun-Wook Chang, Kyeong-Hwa Sim, Youn-Ju Lee. Thalidomide Attenuates Mast Cell Activation by Upregulating SHP-1 Signaling and Interfering with the Action of CRBN.
Cells.
2023 02; 12(3):. doi:
10.3390/cells12030469. [PMID: 36766811] - Yating Li, Jiamei Ji, Hua Lu, Jianyong Li, Xiaoyan Qu. Pomalidomide-based therapy for extramedullary multiple myeloma.
Hematology (Amsterdam, Netherlands).
2022 Dec; 27(1):88-94. doi:
10.1080/16078454.2021.2019364. [PMID: 35068387] - Faouzi Djebbari, Alexandros Rampotas, Grant Vallance, Fotios Panitsas, Nanda Basker, Gina Sangha, Beena Salhan, Farheen Karim, Al-Kaisi Firas, Amy Gudger, Loretta Ngu, Matt Poynton, Ho Pui Jeff Lam, Lowri Morgan, Laura Yang, Jennifer Young, Mairi Walker, Ismini Tsagkaraki, Laura Anderson, Saleena Rani Chauhan, Rebecca Maddams, Richard Soutar, Margarita Triantafillou, Steve Prideaux, Abubaker Obeidalla, Toby A Eyre, Ceri Bygrave, Supratik Basu, Karthik Ramasamy. Infections in relapsed myeloma patients treated with isatuximab plus pomalidomide and dexamethasone during the COVID-19 pandemic: Initial results of a UK-wide real-world study.
Hematology (Amsterdam, Netherlands).
2022 Dec; 27(1):691-699. doi:
10.1080/16078454.2022.2082725. [PMID: 35666686] - Ying Hao, Yitao Ou, Cheng Zhang, Hao Chen, Hu Yue, Zhongjin Yang, Xiaofen Zhong, Wenhui Hu, Ping Sun. Seratrodast, a thromboxane A2 receptor antagonist, inhibits neuronal ferroptosis by promoting GPX4 expression and suppressing JNK phosphorylation.
Brain research.
2022 11; 1795(?):148073. doi:
10.1016/j.brainres.2022.148073. [PMID: 36075466] - Melinda J Gooderham, H Chih-Ho Hong, Ivan V Litvinov. Selective TYK2 Inhibition in the Treatment of Moderate to Severe Chronic Plaque Psoriasis.
Skin therapy letter.
2022 11; 27(6):1-5. doi:
". [PMID: 36469536] - Feng Xiong, Lingmei Kong, Liang Chen, Minggao Xue, Feng Cao, Shuqun Zhang, Hongmei Li, Hui Yan, Yan Li, Zhili Zuo. Discovery of potential novel CRBN modulators by virtual screening and bioassay.
European journal of medicinal chemistry.
2022 Jun; 236(?):114355. doi:
10.1016/j.ejmech.2022.114355. [PMID: 35413617] - Nizar J Bahlis, David S Siegel, Gary J Schiller, Christy Samaras, Michael Sebag, Jesus Berdeja, Siddhartha Ganguly, Jeffrey Matous, Kevin Song, Christopher S Seet, Mirelis Acosta-Rivera, Michael Bar, Donald Quick, Bertrand Anz, Gustavo Fonseca, Weiyuan Chung, Kim Lee, Jorge Mouro, Amit Agarwal, Donna Reece. Pomalidomide, dexamethasone, and daratumumab immediately after lenalidomide-based treatment in patients with multiple myeloma: updated efficacy, safety, and health-related quality of life results from the phase 2 MM-014 trial.
Leukemia & lymphoma.
2022 06; 63(6):1407-1417. doi:
10.1080/10428194.2022.2030477. [PMID: 35133221] - Saman Hewamana, Prasanna Gunasena, Chathuri Jayasinghe, Thurairajah Skandarajah, Mahesh Harischandra, Sobitha Abeyaratne, Lalith Ekanayake, Gnani Somasundaram, Surjit Somiah, Vadivelu Srinivasan, Gehan Arseculeratne, Neomal Perera, Jayaindra Fernando, Mazhar Faiz, Nihal Munasinghe, Ashfaq Mowlana, Samadhi Deshapriya, Supun Mawathakubura, Chandana Wickramarathna, Ananda Wijewickrama, Priyankara Jayawardena, Eranga Perera, Natasha Peiris, Sarath Paranawithane, Chitranganie Perera, Chitranga Kariyawasam, Sanjeewa Munasinghe, Chandu De Silva, Rohini Wadanamby, Geethani Galagoda, Thet Thet Lin, Bandula Wijesiriwardena, Jayantha Balawardena. Response and Survival Estimates of Patients With Plasma Cell Myeloma in a Resource-Constrained Setting Using Protocols From High-Income Countries: A Single-Center Experience From Sri Lanka.
JCO global oncology.
2022 Jun; 8(?):e2100352. doi:
10.1200/go.21.00352. [PMID: 35772042] - Fatiha Rachedi, Kimiko Koiwai, Nadia Gaudel-Dedieu, Bernard Sebastien, Hoai-Thu Thai, Claire Brillac, Jean Baptiste Fau, Laurent Nguyen, Helgi van de Velde, Christine Veyrat-Follet, Dorothée Semiond. Exposure-response analyses for selection/confirmation of optimal isatuximab dosing regimen in combination with pomalidomide/dexamethasone treatment in patients with multiple myeloma.
CPT: pharmacometrics & systems pharmacology.
2022 Jun; 11(6):766-777. doi:
10.1002/psp4.12789. [PMID: 35355430] - Ivan Arias de la Rosa, Maria Dolores López-Montilla, Cristobal Román-Rodríguez, Carlos Pérez-Sánchez, Ignacio Gómez-García, Clementina López-Medina, Maria Lourdes Ladehesa-Pineda, Maria Del Carmen Ábalos-Aguilera, Desiree Ruiz, Alejandra Maria Patiño-Trives, Maria Luque-Tévar, Isabel Añón-Oñate, Maria Jose Pérez-Galán, Rocio Guzmán-Ruiz, Maria M Malagón, Chary López-Pedrera, Alejandro Escudero-Contreras, Eduardo Collantes-Estévez, Nuria Barbarroja. The clinical and molecular cardiometabolic fingerprint of an exploratory psoriatic arthritis cohort is associated with the disease activity and differentially modulated by methotrexate and apremilast.
Journal of internal medicine.
2022 05; 291(5):676-693. doi:
10.1111/joim.13447. [PMID: 35233860] - Dongkui Sui, Hua Yu. Protective roles of apremilast via Sirtuin 1 in atherosclerosis.
Bioengineered.
2022 05; 13(5):13872-13881. doi:
10.1080/21655979.2022.2085390. [PMID: 35707830] - Hoai-Thu Thai, Nadia Gaudel, Marc Cerou, Geraldine Ayral, Jean-Baptiste Fau, Bernard Sebastien, Helgi van de Velde, Dorothée Semiond, Christine Veyrat-Follet. Joint modelling and simulation of M-protein dynamics and progression-free survival for alternative isatuximab dosing with pomalidomide/dexamethasone.
British journal of clinical pharmacology.
2022 05; 88(5):2052-2064. doi:
10.1111/bcp.15123. [PMID: 34705283] - Lyn D Ferguson, Susanne Cathcart, Dominic Rimmer, Gary Semple, Katriona Brooksbank, Caron Paterson, Rosemary Brown, John Harvie, Xuan Gao, Aleksandra Radjenovic, Paul Welsh, Iain B McInnes, Naveed Sattar, Stefan Siebert. Effect of the phosphodiesterase 4 inhibitor apremilast on cardiometabolic outcomes in psoriatic disease-results of the Immune Metabolic Associations in Psoriatic Arthritis study.
Rheumatology (Oxford, England).
2022 03; 61(3):1026-1034. doi:
10.1093/rheumatology/keab474. [PMID: 34097014] - Aneta Szudy-Szczyrek, Radosław Mlak, Michał Mielnik, Marcin Mazurek, Sylwia Chocholska, Martyna Podgajna, Michał Szczyrek, Iwona Homa-Mlak, Teresa Małecka-Massalska, Marek Hus. Circulating Serum MiRNA-8074 as a Novel Prognostic Biomarker for Multiple Myeloma.
Cells.
2022 02; 11(4):. doi:
10.3390/cells11040752. [PMID: 35203396] - S M A Ahmed, M Volontè, E Isoletta, C Vassallo, C F Tomasini, D Lilleri, P Zelini, V Musella, C Klersy, V Brazzelli. SARS-CoV-2 serology in patients on biological therapy or apremilast for psoriasis: a study of 93 patients in the Italian red zone.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2022 Feb; 36(2):e86-e88. doi:
10.1111/jdv.17721. [PMID: 34606128] - Y Lytvyn, J R Georgakopoulos, A Mufti, A R Devani, M J Gooderham, V Jain, P Lansang, R Vender, V H Prajapati, J Yeung. Incidence and prognosis of COVID-19 in patients with psoriasis on apremilast: a multicentre retrospective cohort study.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2022 Feb; 36(2):e94-e95. doi:
10.1111/jdv.17749. [PMID: 34657332] - Fredrik H Schjesvold, Meletios-Athanasios Dimopoulos, Sosana Delimpasi, Pawel Robak, Daniel Coriu, Wojciech Legiec, Luděk Pour, Ivan Špička, Tamas Masszi, Vadim Doronin, Jiri Minarik, Galina Salogub, Yulia Alekseeva, Antonio Lazzaro, Vladimir Maisnar, Gábor Mikala, Laura Rosiñol, Anna Marina Liberati, Argiris Symeonidis, Victoria Moody, Marcus Thuresson, Catriona Byrne, Johan Harmenberg, Nicolaas A Bakker, Roman Hájek, Maria-Victoria Mateos, Paul G Richardson, Pieter Sonneveld. Melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide (OCEAN): a randomised, head-to-head, open-label, phase 3 study.
The Lancet. Haematology.
2022 Feb; 9(2):e98-e110. doi:
10.1016/s2352-3026(21)00381-1. [PMID: 35032434] - Takafumi Ide, Mayu Osawa, Kinjal Sanghavi, Heather E Vezina. Population pharmacokinetic and exposure-response analyses of elotuzumab plus pomalidomide and dexamethasone for relapsed and refractory multiple myeloma.
Cancer chemotherapy and pharmacology.
2022 01; 89(1):129-140. doi:
10.1007/s00280-021-04365-4. [PMID: 34825942] - Maria Francesca Palmas, Anna Ena, Chiara Burgaletto, Maria Antonietta Casu, Giuseppina Cantarella, Ezio Carboni, Michela Etzi, Alfonso De Simone, Giuliana Fusco, Maria Cristina Cardia, Francesco Lai, Luca Picci, David Tweedie, Michael T Scerba, Valentina Coroneo, Renato Bernardini, Nigel H Greig, Augusta Pisanu, Anna R Carta. Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson's Disease.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.
2022 01; 19(1):305-324. doi:
10.1007/s13311-022-01182-2. [PMID: 35072912] - Dingqiang Fu, Yi Yuan, Fengming Qin, Yan Xu, Xin Cui, Guangxun Li, Shaohua Yao, Yun Deng, Zhuo Tang. Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs.
European journal of medicinal chemistry.
2021 Dec; 226(?):113850. doi:
10.1016/j.ejmech.2021.113850. [PMID: 34628235] - Di Wang, Yan Wang, Shiren Sun. Renal pathological changes after successful treatment of LCDD using cyclophosphamide, thalidomide, and dexamethasone.
Renal failure.
2021 Dec; 43(1):1425-1427. doi:
10.1080/0886022x.2021.1988967. [PMID: 34657562] - Paul G Richardson, Simon J Harrison, Sara Bringhen, Fredrik Schjesvold, Kwee Yong, Frank Campana, Solenn Le-Guennec, Sandrine Macé, Meletios A Dimopoulos. Isatuximab for relapsed/refractory multiple myeloma: review of key subgroup analyses from the Phase III ICARIA-MM study.
Future oncology (London, England).
2021 Dec; 17(34):4797-4812. doi:
10.2217/fon-2021-0568. [PMID: 34521277] - Jiang-Ming Chen, Wei-Jian Zhu, Jie Liu, Gui-Zhen Wang, Xiao-Qin Chen, Yun Tan, Wei-Wei Xu, Li-Wei Qu, Jin-Yan Li, Huan-Ju Yang, Lan Huang, Ning Cai, Wei-Da Wang, Ken Huang, Jian-Quan Xu, Guo-Hui Li, Sheng He, Tian-Ying Luo, Yi Huang, Song-Hua Liu, Wen-Qiang Wu, Qi-Yang Lu, Mei-Guang Zhou, Shu-Ying Chen, Rong-Lan Li, Mei-Ling Hu, Ying Huang, Jin-Hua Wei, Jun-Min Li, Sai-Juan Chen, Guang-Biao Zhou. Safety and efficacy of thalidomide in patients with transfusion-dependent β-thalassemia: a randomized clinical trial.
Signal transduction and targeted therapy.
2021 11; 6(1):405. doi:
10.1038/s41392-021-00811-0. [PMID: 34795208] - Yukari Okubo, Mamitaro Ohtsuki, Mayumi Komine, Shinichi Imafuku, Nastya Kassir, Rosemary Petric, Osamu Nemoto. Population pharmacokinetic and exposure-response analysis of apremilast in Japanese subjects with moderate to severe psoriasis.
The Journal of dermatology.
2021 Nov; 48(11):1652-1664. doi:
10.1111/1346-8138.16068. [PMID: 34396569] - A Pacifico, A d'Arino, P D M Pigatto, P Malagoli, Young Dermatologists Italian Network, G Damiani. COVID-19 vaccines do not trigger psoriasis flares in patients with psoriasis treated with apremilast.
Clinical and experimental dermatology.
2021 10; 46(7):1344-1346. doi:
10.1111/ced.14723. [PMID: 33969530] - Vamshi Krishna Rapalli, Swati Sharma, Aniruddha Roy, Gautam Singhvi. Design and dermatokinetic evaluation of Apremilast loaded nanostructured lipid carriers embedded gel for topical delivery: A potential approach for improved permeation and prolong skin deposition.
Colloids and surfaces. B, Biointerfaces.
2021 Oct; 206(?):111945. doi:
10.1016/j.colsurfb.2021.111945. [PMID: 34216849] - Lakshmikirupa Sundaresan, Suvendu Giri, Himanshi Singh, Suvro Chatterjee. Repurposing of thalidomide and its derivatives for the treatment of SARS-coV-2 infections: Hints on molecular action.
British journal of clinical pharmacology.
2021 10; 87(10):3835-3850. doi:
10.1111/bcp.14792. [PMID: 33609410] - Alexandre Chagas Santana, Wellington Andraus, Filipe Miranda Oliveira Silva, Humberto Dellê, Rafael Pepineli, Edvaldo Leal de Moraes, Cristoforo Scavone, Larissa de Sá Lima, Sabrina Degaspari, Sergio Brasil, Davi Jorge Fontoura Solla, Liliane Moreira Ruiz, Karina Andrighetti de Oliveira-Braga, Natalia Aparecida Nepomuceno, Paulo Manuel Pêgo-Fernandes, Stefan Gunther Tullius, Eberval Gadelha Figueiredo. Immunomodulatory effects of thalidomide in an experimental brain death liver donor model.
Scientific reports.
2021 09; 11(1):19221. doi:
10.1038/s41598-021-98538-z. [PMID: 34584130] - Hanako Koguchi-Yoshioka, Rei Watanabe, Yutaka Matsumura, Yosuke Ishitsuka, Sae Inoue, Junichi Furuta, Yoshiyuki Nakamura, Naoko Okiyama, Takashi Matsuzaka, Hitoshi Shimano, Yasuhiro Fujisawa, Manabu Fujimoto. Serum lactate dehydrogenase level as a possible predictor of treatment preference in psoriasis.
Journal of dermatological science.
2021 Aug; 103(2):109-115. doi:
10.1016/j.jdermsci.2021.07.007. [PMID: 34332850] - Pim Aarts, Koen Dudink, Allard R J V Vossen, Kelsey R van Straalen, Christine B Ardon, Errol P Prens, Hessel H van der Zee. Clinical Implementation of Biologics and Small Molecules in the Treatment of Hidradenitis Suppurativa.
Drugs.
2021 Aug; 81(12):1397-1410. doi:
10.1007/s40265-021-01566-2. [PMID: 34283386] - Keyvan Amirshahrokhi. Thalidomide reduces glycerol-induced acute kidney injury by inhibition of NF-κB, NLRP3 inflammasome, COX-2 and inflammatory cytokines.
Cytokine.
2021 08; 144(?):155574. doi:
10.1016/j.cyto.2021.155574. [PMID: 33975771] - Selma Regina Penha Silva Cerqueira, Patrícia Duarte Deps, Débora Vilela Cunha, Natanael Victor Furtunato Bezerra, Daniel Holanda Barroso, Ana Bárbara Sapienza Pinheiro, Gecilmara Salviato Pillegi, Taynah Alves Rocha Repsold, Patrícia Shu Kurizky, Simon M Collin, Ciro Martins Gomes. The influence of leprosy-related clinical and epidemiological variables in the occurrence and severity of COVID-19: A prospective real-world cohort study.
PLoS neglected tropical diseases.
2021 07; 15(7):e0009635. doi:
10.1371/journal.pntd.0009635. [PMID: 34319982] - Philippe Moreau, Meletios-Athanasios Dimopoulos, Joseph Mikhael, Kwee Yong, Marcelo Capra, Thierry Facon, Roman Hajek, Ivan Špička, Ross Baker, Kihyun Kim, Gracia Martinez, Chang-Ki Min, Ludek Pour, Xavier Leleu, Albert Oriol, Youngil Koh, Kenshi Suzuki, Marie-Laure Risse, Gaelle Asset, Sandrine Macé, Thomas Martin. Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial.
Lancet (London, England).
2021 06; 397(10292):2361-2371. doi:
10.1016/s0140-6736(21)00592-4. [PMID: 34097854] - Gioacchino Li Cavoli, Anxur Merenda, Onofrio Schillaci, Camillo Carollo, Carmela Zagarrigo, Franca Servillo, Mattia Palmeri, Tancredi Vincenzo Li Cavoli. The Safety of Carfilzomib Therapy in Patients on Long-Term Hemodialysis and Multiple Myeloma.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2021 May; 32(3):896-897. doi:
10.4103/1319-2442.336794. [PMID: 35102941] - O G Artamonova, A E Karamova, A A Nikonorov, D A Verbenko, E L Vasileva, A A Kubanov. The Effect of Janus Kinase Inhibitors and Phosphodiesterase-4 Inhibitors on Skin and Plasma Cytokine Levels in Patients with Psoriasis.
Bulletin of experimental biology and medicine.
2021 May; 171(2):208-211. doi:
10.1007/s10517-021-05196-2. [PMID: 34173094] - Xin Ma, Xu-Feng He, Yan-Xin Tian, Yong-Mei Li, Hui-Min Zhang. Combination therapy of Traditional Chinese Medicine and thalidomide to treat sarcoidosis: A case report.
Explore (New York, N.Y.).
2021 May; 17(3):233-235. doi:
10.1016/j.explore.2020.04.005. [PMID: 32527683] - Donovan G Kearns, Shelley Uppal, Vipawee S Chat, Jashin J Wu. Assessing the Risk of Apremilast Use for Psoriasis During the COVID-19 Pandemic.
Journal of drugs in dermatology : JDD.
2021 May; 20(5):582-583. doi:
10.36849/jdd.5730. [PMID: 33938697] - Emily Figueiredo Neves Yuki, Renata Soares, Léonard de Vinci Kanda Kupa, Carlos Otto Heise, Nadia Emi Aikawa, Marcelo Arnone, Ricardo Romiti, Tatiana do Nascimento Pedrosa, Clovis Artur Almeida da Silva, Eloisa Bonfa, Sandra Gofinet Pasoto. One-year prospective nerve conduction study of thalidomide neuropathy in lupus erythematosus: Incidence, coasting effect and drug plasma levels.
Lupus.
2021 May; 30(6):956-964. doi:
10.1177/0961203321998433. [PMID: 33657919] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Min Zhao, Min Hu, Yong Chen, Heyi Liu, Yulu Chen, Bin Liu, Baijun Fang. Cereblon modulator CC-885 induces CRBN-dependent ubiquitination and degradation of CDK4 in multiple myeloma.
Biochemical and biophysical research communications.
2021 04; 549(?):150-156. doi:
10.1016/j.bbrc.2021.02.110. [PMID: 33676183] - Gedefaw Getnet Amare, Birhanu Geta Meharie, Yaschilal Muche Belayneh. A drug repositioning success: The repositioned therapeutic applications and mechanisms of action of thalidomide.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2021 Apr; 27(3):673-678. doi:
10.1177/1078155220975825. [PMID: 33249990] - Ahmadreza Arbab, Veronique Saada, Sophie Cotteret, Christophe Marzac, David Ghez. Plasma cell dedifferentiation in refractory multiple myeloma.
British journal of haematology.
2021 04; 193(2):212. doi:
10.1111/bjh.17244. [PMID: 33772753] - Bernard Regidor, Regina Swift, Benjamin Eades, Marsiye Emamy-Sadr, Fadi Tarhini, Tanya M Spektor, James R Berenson. Frequent occurrence of hypophosphatemia among multiple myeloma patients treated with elotuzumab: a single clinic retrospective study.
Annals of hematology.
2021 Apr; 100(4):1079-1085. doi:
10.1007/s00277-020-04351-5. [PMID: 33237342] - Anum Qureshi, Ji Hyun Rhee. Hyponatraemia due to hypothyroidism: a rare side effect from pomalidomide.
BMJ case reports.
2021 Mar; 14(3):. doi:
10.1136/bcr-2020-240168. [PMID: 33653858] - Pankaj Bansal, Amandeep Goyal, Austin Cusick, Fawad Aslam. Use of Apremilast in Patients With Psoriatic Arthritis During the COVID-19 Pandemic: Comment on the Article by Mikuls et al.
Arthritis & rheumatology (Hoboken, N.J.).
2021 03; 73(3):547-548. doi:
10.1002/art.41575. [PMID: 33142038] - M Talamonti, L Tofani, L Bianchi, M Galluzzo. Optimizing care for psoriatic patients requiring systemic therapies: how will COVID-19 disease transform risk perceptions?.
Archives of dermatological research.
2021 03; 313(2):127-128. doi:
10.1007/s00403-020-02103-z. [PMID: 32647977] - Fabrizio Bossa, Sonia Carparelli, Anna Latiano, Orazio Palmieri, Francesca Tavano, Anna Panza, Maria Pastore, Antonio Marseglia, Mario D'Altilia, Tiziana Latiano, Giuseppe Corritore, Giuseppina Martino, Marianna Nardella, Maria Guerra, Fulvia Terracciano, Michele Sacco, Francesco Perri, Angelo Andriulli. Impact of the COVID-19 outbreak and the serum prevalence of SARS-CoV-2 antibodies in patients with inflammatory bowel disease treated with biologic drugs.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2021 03; 53(3):277-282. doi:
10.1016/j.dld.2020.12.120. [PMID: 33423942] - Yuping Li, Keqing Shi, Feng Qi, Zhijie Yu, Chengshui Chen, Jingye Pan, Gaojun Wu, Yanfang Chen, Ji Li, Yongping Chen, Tieli Zhou, Xiaokun Li, Jinglin Xia. Thalidomide combined with short-term low-dose glucocorticoid therapy for the treatment of severe COVID-19: A case-series study.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2021 Feb; 103(?):507-513. doi:
10.1016/j.ijid.2020.12.023. [PMID: 33333254] - Rui-Hua Mi, Lin Chen, Ya-Lan Zhou, Dong-Bei Li, Sha Liu, Xiao-Jiao Wang, Jia Liu, Min-Fang Wang, Xiao-Miao Ma, Zhi-Chun Li, Hong-Mian Zhao, Yu-Lin Xu, Shu-Xia Chen, Hai-Ping Yang, Zhi-Qiang Guo, Chun-Lai Luan, Shu-Li Guo, Qing-Lin Song, Xu-Dong Wei. [Synergistic Mechanism of Interferon alpha-1b, Interleukin-2 and Thalidomide for Immune Regulation in Patients with Acute Myeloid Leukemia].
Zhongguo shi yan xue ye xue za zhi.
2021 Feb; 29(1):26-31. doi:
10.19746/j.cnki.issn.1009-2137.2021.01.004. [PMID: 33554792] - Marco Cippitelli, Helena Stabile, Andrea Kosta, Sara Petillo, Angela Gismondi, Angela Santoni, Cinzia Fionda. Role of Aiolos and Ikaros in the Antitumor and Immunomodulatory Activity of IMiDs in Multiple Myeloma: Better to Lose Than to Find Them.
International journal of molecular sciences.
2021 Jan; 22(3):. doi:
10.3390/ijms22031103. [PMID: 33499314] - Makiko Kuwagata, Takuro Hasegawa, Hiromasa Takashima, Makiko Shimizu, Satoshi Kitajima, Hiroshi Yamazaki. Pharmacokinetics of primary metabolites 5-hydroxythalidomide and 5'-hydroxythalidomide formed after oral administration of thalidomide in the rabbit, a thalidomide-sensitive species.
The Journal of toxicological sciences.
2021; 46(12):553-560. doi:
10.2131/jts.46.553. [PMID: 34853241] - Linlin Sui, Yuzhen Li, Zhiying Xu, Xuejun Shen. Therapeutic effect of thalidomide combined with temozolomide and three-dimensional conformal radiotherapy for patients with high-grade gliomas after operation.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2021 Jan; 26(1):2608-2615. doi:
. [PMID: 33721435] - Tomonori Miura, Shotaro Uehara, Makiko Shimizu, Hiroshi Suemizu, Hiroshi Yamazaki. Pharmacokinetics of primary oxidative metabolites of thalidomide in rats and in chimeric mice humanized with different human hepatocytes.
The Journal of toxicological sciences.
2021; 46(7):311-317. doi:
10.2131/jts.46.311. [PMID: 34193768] - Shinichi Imafuku, Osamu Nemoto, Yukari Okubo, Mayumi Komine, Peter Schafer, Rosemary Petric, Mamitaro Ohtsuki. Pharmacodynamic analysis of apremilast in Japanese patients with moderate to severe psoriasis: Results from a phase 2b randomized trial.
The Journal of dermatology.
2021 Jan; 48(1):80-84. doi:
10.1111/1346-8138.15596. [PMID: 32909643] - Isin Yagmur Comba, Anthony Chahin, Hiffsa Taj, Allison Carilli. Pomalidomide and dexamethasone in myelomatous pleural effusion.
BMJ case reports.
2020 Dec; 13(12):. doi:
10.1136/bcr-2020-235899. [PMID: 33303498] - Liqun Chen, Yanke Chen, Chunyan Zhang, Bingyang Jiao, Sheng Liang, Qiong Tan, Hongyu Chai, Weihua Yu, Yongzheng Qian, Hui Yang, Wuyi Yao, Jianguo Yu, Ying Luo, Michael Plewe, Jialiang Wang, Xiao-Ran Han, Jing Liu. Discovery of First-In-Class Potent and Selective Tropomyosin Receptor Kinase Degraders.
Journal of medicinal chemistry.
2020 12; 63(23):14562-14575. doi:
10.1021/acs.jmedchem.0c01342. [PMID: 33058680] - Chao-Tao Tang, Qing-Wei Zhang, Shan Wu, Ming-Yu Tang, Qian Liang, Xiao-Lu Lin, Yun-Jie Gao, Zhi-Zheng Ge. Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation.
Cellular and molecular life sciences : CMLS.
2020 Dec; 77(24):5207-5221. doi:
10.1007/s00018-020-03465-3. [PMID: 32008086] - Katharina Helene Susek, Charlotte Gran, Hans-Gustaf Ljunggren, Evren Alici, Hareth Nahi. Outcome of COVID-19 in multiple myeloma patients in relation to treatment.
European journal of haematology.
2020 Dec; 105(6):751-754. doi:
10.1111/ejh.13502. [PMID: 32745304] - Krzysztof Zduniak, Katarzyna Gdesz-Birula, Marta Woźniak, Kamila Duś-Szachniewicz, Piotr Ziółkowski. The Assessment of the Combined Treatment of 5-ALA Mediated Photodynamic Therapy and Thalidomide on 4T1 Breast Carcinoma and 2H11 Endothelial Cell Line.
Molecules (Basel, Switzerland).
2020 Nov; 25(21):. doi:
10.3390/molecules25215184. [PMID: 33171718] - Agata Kowalczyk, Piotr F J Lipiński, Krzysztof Karoń, Joanna E Rode, Krzysztof Lyczko, Jan Cz Dobrowolski, Mikołaj Donten, Dorota Kaczorek, Joanna Poszytek, Robert Kawęcki, Mieczysław Łapkowski, Anna Malkowska, Ireneusz P Grudzinski, Anna M Nowicka. Enantioselective sensing of (S)-Thalidomide in blood plasma with a chiral naphthalene diimide derivative.
Biosensors & bioelectronics.
2020 Nov; 167(?):112446. doi:
10.1016/j.bios.2020.112446. [PMID: 32818748] - Linlin Sui, Yuzhen Li, Zhiying Xu, Xuejun Shen. Therapeutic effect of thalidomide combined with temozolomide and three-dimensional conformal radiotherapy for patients with high-grade gliomas after operation.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2020 Nov; 25(6):2608-2615. doi:
. [PMID: 33455103] - Jingying Wang, Yan Zhang, Meng Pan. Thalidomide as a potential adjuvant treatment for paraneoplastic pemphigus: A single-center experience.
Dermatologic therapy.
2020 11; 33(6):e14353. doi:
10.1111/dth.14353. [PMID: 32990359] - Rubén Queiro Silva, Susana Armesto, Carmen González Vela, Cristina Naharro Fernández, Miguel Angel González-Gay. COVID-19 patients with psoriasis and psoriatic arthritis on biologic immunosuppressant therapy vs apremilast in North Spain.
Dermatologic therapy.
2020 11; 33(6):e13961. doi:
10.1111/dth.13961. [PMID: 32618402] - Susana Armesto, Carmen González Vela, Julia Sánchez, Aitziber Illaro, Jesús Mayorga, Ana E López Sundh, Cristina Naharro Fernández, Natalia Palmou, Cristina Gómez-Fernández, Marcos A González López, Miguel A González-Gay. Treating multidrug-resistant psoriasis with brodalumab, apremilast, methotrexate and prednisone combination therapy in the COVID-19 pandemic.
Dermatologic therapy.
2020 11; 33(6):e14464. doi:
10.1111/dth.14464. [PMID: 33112014] - Chirag A Shah. Can roflumilast become steroid-sparing alternative in the treatment of COVID-19?.
Medical hypotheses.
2020 Nov; 144(?):110246. doi:
10.1016/j.mehy.2020.110246. [PMID: 33254551] - Jean-Baptiste Fau, Raouf El-Cheikh, Claire Brillac, Kimiko Koiwai, Nathalie Mace, Frank Campana, Dorothee Semiond, Laurent Nguyen. Drug-Disease Interaction and Time-Dependent Population Pharmacokinetics of Isatuximab in Relapsed/Refractory Multiple Myeloma Patients.
CPT: pharmacometrics & systems pharmacology.
2020 11; 9(11):649-658. doi:
10.1002/psp4.12561. [PMID: 33021075] - Jing Li, Li Bao, Zhongjun Xia, Sili Wang, Xin Zhou, Kaiyang Ding, Wenhao Zhang, Wei Yang, Bingzong Li, Chengcheng Fu, Bing Chen, Luoming Hua, Liang Wang, Jun Luo, Yang Yang, Tianhong Xu, Weida Wang, Yun Huang, Guolin Wu, Peng Liu. Ixazomib-based frontline therapy in patients with newly diagnosed multiple myeloma in real-life practice showed comparable efficacy and safety profile with those reported in clinical trial: a multi-center study.
Annals of hematology.
2020 Nov; 99(11):2589-2598. doi:
10.1007/s00277-020-04234-9. [PMID: 32892275] - Katarzyna A Jalowiec, Martin Andres, Behrouz Mansouri Taleghani, Albulena Musa, Martina Dickenmann, Anne Angelillo-Scherrer, Alicia Rovó, Johanna A Kremer Hovinga. Acquired hemophilia A and plasma cell neoplasms: a case report and review of the literature.
Journal of medical case reports.
2020 Oct; 14(1):206. doi:
10.1186/s13256-020-02505-7. [PMID: 33121522] - Samantha Hinsley, Katrina Walker, Debbie Sherratt, Lucy Bailey, Sadie Reed, Louise Flanagan, Sophie McKee, Fiona Brudenell Straw, Bryony Dawkins, David Meads, Holger W Auner, Martin F Kaiser, Mark Cook, Sarah Brown, Gordon Cook. The MUK eight protocol: a randomised phase II trial of cyclophosphamide and dexamethasone in combination with ixazomib, in relapsed or refractory multiple myeloma (RRMM) patients who have relapsed after treatment with thalidomide, lenalidomide and a proteasome inhibitor.
Trials.
2020 Oct; 21(1):826. doi:
10.1186/s13063-020-04739-8. [PMID: 33008427] - Aneta Szudy-Szczyrek, Radosław Mlak, Magdalena Bury-Kamińska, Michał Mielnik, Martyna Podgajna, Kinga Kuśmierczuk, Marcin Mazurek, Iwona Homa-Mlak, Michał Szczyrek, Janusz Krawczyk, Teresa Małecka-Massalska, Marek Hus. Serum brain-derived neurotrophic factor (BDNF) concentration predicts polyneuropathy and overall survival in multiple myeloma patients.
British journal of haematology.
2020 10; 191(1):77-89. doi:
10.1111/bjh.16862. [PMID: 32567687] - Satoshi Yamanaka, Yuki Shoya, Saya Matsuoka, Hisayo Nishida-Fukuda, Norio Shibata, Tatsuya Sawasaki. An IMiD-induced SALL4 degron system for selective degradation of target proteins.
Communications biology.
2020 09; 3(1):515. doi:
10.1038/s42003-020-01240-5. [PMID: 32948804] - Bing-Bing Hao, Xiao-Jing Li, Xing-Long Jia, Yu-Xing Wang, Lin-Hui Zhai, Duan-Zhuo Li, Jie Liu, Die Zhang, Yu-Lu Chen, Yong-Hu Xu, Sang-Kyu Lee, Guo-Feng Xu, Xiao-Hua Chen, Yong-Jun Dang, Bin Liu, Min-Jia Tan. The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L.
Acta pharmacologica Sinica.
2020 Sep; 41(9):1246-1254. doi:
10.1038/s41401-020-0367-9. [PMID: 32210356] - Rajshekhar Chakraborty, Suzanne Lentzsch. Emerging drugs for the treatment of light chain amyloidosis.
Expert opinion on emerging drugs.
2020 09; 25(3):299-317. doi:
10.1080/14728214.2020.1803829. [PMID: 32731778] - Alessio Pierini, Irene Sartini, Mario Giorgi, Beata Łebkowska-Wieruszewska, Andrzej Lisowski, Amnart Poapolathep, Veronica Marchetti. Pharmacokinetics of thalidomide in dogs: can feeding affect it? A preliminary study.
Journal of veterinary science.
2020 Sep; 21(5):e60. doi:
10.4142/jvs.2020.21.e60. [PMID: 33016014] - V Venerito, D Natuzzi, R Bizzoca, N Lacarpia, F Cacciapaglia, G Lopalco, F Iannone. Serum sCD40L levels are increased in patients with psoriatic arthritis and are associated with clinical response to apremilast.
Clinical and experimental immunology.
2020 08; 201(2):200-204. doi:
10.1111/cei.13451. [PMID: 32383167] - C Mugheddu, L Pizzatti, S Sanna, L Atzori, F Rongioletti. COVID-19 pulmonary infection in erythrodermic psoriatic patient with oligodendroglioma: safety and compatibility of apremilast with critical intensive care management.
Journal of the European Academy of Dermatology and Venereology : JEADV.
2020 Aug; 34(8):e376-e378. doi:
10.1111/jdv.16625. [PMID: 32385859] - Hasan I Atrah. Alternative management of Covid-19 infection.
Scottish medical journal.
2020 Aug; 65(3):72-75. doi:
10.1177/0036933020941497. [PMID: 32638647] - Go Woon Kim, Jung Yoo, Hye-Rim Won, Soo-Keun Yeon, Sang Woo Lee, Dong Hoon Lee, Yu Hyun Jeon, So Hee Kwon. A452, HDAC6-selective inhibitor synergistically enhances the anticancer activity of immunomodulatory drugs in IMiDs-resistant multiple myeloma.
Leukemia research.
2020 08; 95(?):106398. doi:
10.1016/j.leukres.2020.106398. [PMID: 32512378] - Ganesh Kasinathan. Primary plasma cell leukaemia in a 39-year-old man.
BMJ case reports.
2020 Jul; 13(7):. doi:
10.1136/bcr-2020-235543. [PMID: 32709663] - Daniele Melis, Cristina Mugheddu, Silvia Sanna, Laura Atzori, Franco Rongioletti. Clinical efficacy, speed of improvement and safety of apremilast for the treatment of adult Psoriasis during COVID-19 pandemic.
Dermatologic therapy.
2020 Jul; 33(4):e13722. doi:
10.1111/dth.13722. [PMID: 32475036] - Mauricio Goihman-Yahr. Proposed use of thalidomide for the cytokine storm of COVID-19.
Clinics in dermatology.
2020 Jul; 38(4):508. doi:
10.1016/j.clindermatol.2020.04.015. [PMID: 32972614] - Jorge R Georgakopoulos, Ron Vender, Jensen Yeung. Patient-Driven Discontinuation of Apremilast During the COVID-19 Pandemic in Two Canadian Academic Hospital Clinics and One Community Practice.
Journal of cutaneous medicine and surgery.
2020 Jul; 24(4):418-419. doi:
10.1177/1203475420928382. [PMID: 32396018] - Olga Yu Olisova, Ekaterina M Anpilogova, Dariya A Svistunova. Apremilast as a potential treatment option for COVID-19: No symptoms of infection in a psoriatic patient.
Dermatologic therapy.
2020 07; 33(4):e13668. doi:
10.1111/dth.13668. [PMID: 32449265] - Susana Armesto, Carmen González Vela, Marco Antonio González López. Opportunistic virus infections in psoriasis patients: The safer alternative of apremilast in the COVID-19 era.
Dermatologic therapy.
2020 Jul; 33(4):e13618. doi:
10.1111/dth.13618. [PMID: 32424891] - Simona Elba, Alessia Castellino, Roberto Soriasio, Claudia Castellino, Margherita Bonferroni, Daniele Mattei, Giuliana Strola, Daniela Drandi, Nicola Mordini, Miriam Foglietta, Davide Rapezzi, Ivana Celeghini, Mariella Grasso, Fabrizio Giordano, Giulio Fraternali Orcioni, Massimo Massaia. Immunoglobulin M (IgM) multiple myeloma versus Waldenström macroglobulinemia: diagnostic challenges and therapeutic options: two case reports.
Journal of medical case reports.
2020 Jun; 14(1):75. doi:
10.1186/s13256-020-02380-2. [PMID: 32564775] - Z Aydoğmuş, E M Yılmaz, G Yildiz. A simple and rapid spectrofluorometric determination of pomalidomide in spiked plasma and urine. Application to degradation studies.
Luminescence : the journal of biological and chemical luminescence.
2020 Jun; 35(4):466-477. doi:
10.1002/bio.3748. [PMID: 31851418] - Huanping Wang, Haitao Meng, Jinghan Wang, Yinjun Lou, Yile Zhou, Peipei Lin, Fenglin Li, Lin Liu, Huan Xu, Min Yang, Jie Jin. Clinical characteristics and prognostic values of 1p32.3 deletion detected through fluorescence in situ hybridization in patients with newly diagnosed multiple myeloma: a single-center study in China.
Frontiers of medicine.
2020 Jun; 14(3):327-334. doi:
10.1007/s11684-019-0712-x. [PMID: 31784918] - Jyotsana R Madan, Shweta Khobaragade, Kamal Dua, Rajendra Awasthi. Formulation, optimization, and in vitro evaluation of nanostructured lipid carriers for topical delivery of Apremilast.
Dermatologic therapy.
2020 05; 33(3):e13370. doi:
10.1111/dth.13370. [PMID: 32250507] - Tomoki Suichi, Sonoko Misawa, Kengo Nagashima, Yasunori Sato, Yuta Iwai, Kanako Katayama, Yukari Sekiguchi, Kazumoto Shibuya, Hiroshi Amino, Yo-Ichi Suzuki, Atsuko Tsuneyama, Keigo Nakamura, Satoshi Kuwabara. Lenalidomide Treatment for Thalidomide-refractory POEMS Syndrome: A Prospective Single-arm Clinical Trial.
Internal medicine (Tokyo, Japan).
2020 May; 59(9):1149-1153. doi:
10.2169/internalmedicine.3800-19. [PMID: 32009091] - Riccardo Moia, Elena Boggio, Luca Gigliotti, Elena Crisà, Lorenzo De Paoli, Gloria Margiotta Casaluci, Roberta Rolla, Andrea Patriarca, Gianluca Gaidano, Umberto Dianzani, Riccardo Bruna. Anti-rasburicase antibodies induce clinical refractoriness by inhibiting the enzyme catalytic activity.
Hematological oncology.
2020 Apr; 38(2):204-206. doi:
10.1002/hon.2700. [PMID: 31985842] - Manon Sapet, Ludovic Fouillet, Elisabeth Daguenet, Blandine Laurent, Denis Guyotat, Caroline Le Jeune. [Proteinuria in multiple myeloma: Be careful to iatrogeny].
Bulletin du cancer.
2020 Apr; 107(4):519-520. doi:
10.1016/j.bulcan.2020.01.014. [PMID: 32178835]