Fulvestrant (BioDeep_00000398767)
natural product
代谢物信息卡片
7α-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-estra-1,3,5(10)-triene-3,17β-diol
化学式: C32H47F5O3S (606.3165892)
中文名称: 氟维司群
谱图信息:
最多检出来源 Homo sapiens(natural_products) 50%
分子结构信息
SMILES: C1(C=CC2[C@@]3(CC[C@]4([C@H](CC[C@@]([C@]([C@@H](CC(C=1)=2)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F)3[H])4[H])O)C)[H])O
InChI: InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1
描述信息
L - Antineoplastic and immunomodulating agents > L02 - Endocrine therapy > L02B - Hormone antagonists and related agents > L02BA - Anti-estrogens
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2116 - Selective Estrogen Receptor Down Regulator
C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist
D000970 - Antineoplastic Agents
同义名列表
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:31638
- KEGGdrug: D01161
- PubChem: 104741
- Metlin: METLIN45325
- DrugBank: DB00947
- ChEMBL: CHEMBL1358
- MeSH: Fulvestrant
- CAS: 1316849-17-8
- CAS: 129453-61-8
- MoNA: CCMSLIB00000004620
- MoNA: CCMSLIB00000078037
- MoNA: CCMSLIB00000004628
- MoNA: CCMSLIB00000004627
- MoNA: CCMSLIB00000004626
- MoNA: CCMSLIB00000004625
- MoNA: CCMSLIB00000004624
- MoNA: CCMSLIB00000004623
- MoNA: CCMSLIB00000004622
- MoNA: CCMSLIB00000004621
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Guisen Yin, Guiling Song, Shuyi Xue, Fen Liu. Adverse event signal mining and serious adverse event influencing factor analysis of fulvestrant based on FAERS database.
Scientific reports.
2024 05; 14(1):11367. doi:
10.1038/s41598-024-62238-1. [PMID: 38762547] - Yuhang Wang, Shuo Zhao, Shuhong Wang, Jing Zhang, Yanli Zhao, Cai Ye, Zhiyu Zhao, Jinlian Li, Hongkuan Shen, Dongmei Wu. Electrochemistry detection of estrogenic effect: Regulation of de novo purine synthesis and catabolism by gibberellin and fulvestrant.
Bioelectrochemistry (Amsterdam, Netherlands).
2024 Apr; 156(?):108634. doi:
10.1016/j.bioelechem.2023.108634. [PMID: 38160510] - Shaymaa Bahnassy, Hillary Stires, Lu Jin, Stanley Tam, Dua Mobin, Manasi Balachandran, Mircea Podar, Matthew D McCoy, Robert A Beckman, Rebecca B Riggins. Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer.
Endocrinology.
2023 Nov; 164(12):. doi:
10.1210/endocr/bqad159. [PMID: 37897495] - Cong-Shu Huang, Hui-Fang Deng, Lei Zhou, Pan Shen, Yu-Hao Ni, Ning-Ning Wang, Gao-Fu Li, Lan-Xin Yue, Yong-Qiang Zhou, Wei Zhou, Yue Gao. Undesirable ER stress induced by bavachin contributed to follicular atresia in zebrafish ovary.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Oct; 166(?):115322. doi:
10.1016/j.biopha.2023.115322. [PMID: 37586115] - Eric N Donders, Kai V Slaughter, Christian Dank, Ahil N Ganesh, Brian K Shoichet, Mark Lautens, Molly S Shoichet. Synthetic Ionizable Colloidal Drug Aggregates Enable Endosomal Disruption.
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
2023 05; 10(13):e2300311. doi:
10.1002/advs.202300311. [PMID: 36905240] - Jiayu Wang, Li Cai, Yanqiu Song, Tao Sun, Zhongsheng Tong, Yuee Teng, Huiping Li, Quchang Ouyang, Qianjun Chen, Shude Cui, Yongmei Yin, Ning Liao, Qiang Sun, Jifeng Feng, Xiaojia Wang, Binghe Xu. Clinical efficacy of fulvestrant versus exemestane as first-line therapies for Chinese postmenopausal oestrogen-receptor positive /human epidermal growth factor receptor 2 -advanced breast cancer (FRIEND study).
European journal of cancer (Oxford, England : 1990).
2023 Feb; 184(?):73-82. doi:
10.1016/j.ejca.2023.02.007. [PMID: 36905771] - Ning Xu, Yuanran Chen, Dongjie Guo, Yu Deng, Wanjun Guo, Xin Liu, Yi Wang, Hanzhi Lu, Aijun Liu, Jianyong Zhu, Fulun Li. Rhein promotes the proliferation of keratinocytes by targeting oestrogen receptors for skin ulcer treatment.
BMC complementary medicine and therapies.
2022 Aug; 22(1):209. doi:
10.1186/s12906-022-03691-1. [PMID: 35932049] - Megan K McLean, Thomas W Geary, Abby L Zezeski, Michael F Smith, Thomas E Spencer, Ky G Pohler, Sydney T Reese, George A Perry. Impact of preovulatory estradiol concentrations on subsequent luteal function in beef cattle.
Systems biology in reproductive medicine.
2022 Aug; 68(4):286-297. doi:
10.1080/19396368.2022.2038717. [PMID: 35394393] - Ruhainee Tohkayomatee, Somrudee Reabroi, Duangjai Tungmunnithum, Warisara Parichatikanond, Darawan Pinthong. Andrographolide Exhibits Anticancer Activity against Breast Cancer Cells (MCF-7 and MDA-MB-231 Cells) through Suppressing Cell Proliferation and Inducing Cell Apoptosis via Inactivation of ER-α Receptor and PI3K/AKT/mTOR Signaling.
Molecules (Basel, Switzerland).
2022 May; 27(11):. doi:
10.3390/molecules27113544. [PMID: 35684480] - Luca Malorni, Svitlana Tyekucheva, Florentine S Hilbers, Michail Ignatiadis, Patrick Neven, Marco Colleoni, Stéphanie Henry, Alberto Ballestrero, Andrea Bonetti, Guy Jerusalem, Konstantinos Papadimitriou, Antonio Bernardo, Elena Seles, Francois P Duhoux, Iain R MacPherson, Alastair Thomson, David Mark Davies, Mattias Bergqvist, Ilenia Migliaccio, Géraldine Gebhart, Gabriele Zoppoli, Judith M Bliss, Matteo Benelli, Amelia McCartney, Roswitha Kammler, Heidi De Swert, Barbara Ruepp, Debora Fumagalli, Rudolf Maibach, David Cameron, Sherene Loi, Martine Piccart, Meredith M Regan. Serum thymidine kinase activity in patients with hormone receptor-positive and HER2-negative metastatic breast cancer treated with palbociclib and fulvestrant.
European journal of cancer (Oxford, England : 1990).
2022 03; 164(?):39-51. doi:
10.1016/j.ejca.2021.12.030. [PMID: 35172272] - Laurence Dahbi, Amaury Farce, Nicolas Kambia, Isabelle Séverin, Thierry Dine, Emmanuel Moreau, Valérie Sautou, Marie-Christine Chagnon. In vitro and in silico approach to study the hormonal activities of the alternative plasticizer tri-(2-ethylhexyl) trimellitate TEHTM and its metabolites.
Archives of toxicology.
2022 03; 96(3):899-918. doi:
10.1007/s00204-022-03230-4. [PMID: 35089383] - Jing-Bo Liu, Zi-Fa Li, Lu Lu, Zhen-Yong Wang, Lin Wang. Glyphosate damages blood-testis barrier via NOX1-triggered oxidative stress in rats: Long-term exposure as a potential risk for male reproductive health.
Environment international.
2022 01; 159(?):107038. doi:
10.1016/j.envint.2021.107038. [PMID: 34906888] - Shui Lian Chou, Samiraj Ramesh, Chia-Hua Kuo, Ayaz Ali, Tsung-Jung Ho, Ko Peng Chang, Dennis Jine-Yuan Hsieh, V Bharath Kumar, Yueh-Shan Weng, Wei-Wen Kuo, Chih-Yang Huang. Tanshinone IIA inhibits Leu27IGF-II-induced insulin-like growth factor receptor II signaling and myocardial apoptosis via estrogen receptor-mediated Akt activation.
Environmental toxicology.
2022 Jan; 37(1):142-150. doi:
10.1002/tox.23385. [PMID: 34655285] - Lin Sun, Jiahui Li, Jie Li, Ke Pei, Zhi Chai, Song Huang, Shaozhen Hou. Effects and mechanism of Pigeonpea (Cajanus cajan (L.) Millsp.) leaves on proliferation, migration, and tube formation of hypoxic human umbilical vein endothelial cells in vitro.
Journal of ethnopharmacology.
2021 Oct; 279(?):114394. doi:
10.1016/j.jep.2021.114394. [PMID: 34245834] - Jin Tae Kim, Hong Jin Lee, Hee-Seok Lee. Organophosphorus pesticides exert estrogen receptor agonistic effect determined using Organization for Economic Cooperation and Development PBTG455, and induce estrogen receptor-dependent adipogenesis of 3T3-L1 adipocytes.
Environmental pollution (Barking, Essex : 1987).
2021 Aug; 283(?):117090. doi:
10.1016/j.envpol.2021.117090. [PMID: 33872936] - Gary Schwartz, Kevin Shee, Bianca Romo, Jonathan Marotti, Alexei Kisselev, Lionel Lewis, Todd Miller. Phase Ib Study of the Oral Proteasome Inhibitor Ixazomib (MLN9708) and Fulvestrant in Advanced ER+ Breast Cancer Progressing on Fulvestrant.
The oncologist.
2021 06; 26(6):467-e924. doi:
10.1002/onco.13733. [PMID: 33641211] - Wei Jiang, Zhichao He, Tiantian Zhang, Chongchong Guo, Jianli Zhao, Jianhong Zhu, Junyan Wu, Xiaoxia Yu, Chuxiong Chen, Jianfang Li, Jie Jiang. Cost-effectiveness analysis of ribociclib plus fulvestrant for hormone receptor-positive/human EGF receptor 2-negative breast cancer.
Immunotherapy.
2021 06; 13(8):661-668. doi:
10.2217/imt-2020-0237. [PMID: 33876668] - Lauren Darrigues, Jean-Yves Pierga, Alice Bernard-Tessier, Ivan Bièche, Amanda Bartolini Silveira, Marc Michel, Delphine Loirat, Paul Cottu, Luc Cabel, Coraline Dubot, Romain Geiss, Francesco Ricci, Anne Vincent-Salomon, Charlotte Proudhon, François-Clément Bidard. Circulating tumor DNA as a dynamic biomarker of response to palbociclib and fulvestrant in metastatic breast cancer patients.
Breast cancer research : BCR.
2021 03; 23(1):31. doi:
10.1186/s13058-021-01411-0. [PMID: 33676547] - Ben O'Leary, Rosalind J Cutts, Xin Huang, Sarah Hrebien, Yuan Liu, Fabrice André, Sibylle Loibl, Sherene Loi, Isaac Garcia-Murillas, Massimo Cristofanilli, Cynthia Huang Bartlett, Nicholas C Turner. Circulating Tumor DNA Markers for Early Progression on Fulvestrant With or Without Palbociclib in ER+ Advanced Breast Cancer.
Journal of the National Cancer Institute.
2021 03; 113(3):309-317. doi:
10.1093/jnci/djaa087. [PMID: 32940689] - Zi Long, Junshu Fan, Guangyuan Wu, Xiyu Liu, Hao Wu, Jiangzheng Liu, Yao Chen, Shuhao Su, Xiaodong Cheng, Zhongrui Xu, Hongfei Su, Meng Cao, Chunping Zhang, Chunxu Hai, Xin Wang. Gestational bisphenol A exposure induces fatty liver development in male offspring mice through the inhibition of HNF1b and upregulation of PPARγ.
Cell biology and toxicology.
2021 02; 37(1):65-84. doi:
10.1007/s10565-020-09535-3. [PMID: 32623698] - Javier Pascual, Joline S J Lim, Iain R Macpherson, Anne C Armstrong, Alistair Ring, Alicia F C Okines, Rosalind J Cutts, Maria Teresa Herrera-Abreu, Isaac Garcia-Murillas, Alex Pearson, Sarah Hrebien, Heidrun Gevensleben, Paula Z Proszek, Michael Hubank, Margaret Hills, Jenny King, Mona Parmar, Toby Prout, Laura Finneran, Jason Malia, Karen E Swales, Ruth Ruddle, Florence I Raynaud, Alison Turner, Emma Hall, Timothy A Yap, Juanita S Lopez, Nicholas C Turner. Triplet Therapy with Palbociclib, Taselisib, and Fulvestrant in PIK3CA-Mutant Breast Cancer and Doublet Palbociclib and Taselisib in Pathway-Mutant Solid Cancers.
Cancer discovery.
2021 01; 11(1):92-107. doi:
10.1158/2159-8290.cd-20-0553. [PMID: 32958578] - Nicholas C Turner, Claire Swift, Lucy Kilburn, Charlotte Fribbens, Matthew Beaney, Isaac Garcia-Murillas, Aman U Budzar, John F R Robertson, William Gradishar, Martine Piccart, Gaia Schiavon, Judith M Bliss, Mitch Dowsett, Stephen R D Johnston, Stephen K Chia. ESR1 Mutations and Overall Survival on Fulvestrant versus Exemestane in Advanced Hormone Receptor-Positive Breast Cancer: A Combined Analysis of the Phase III SoFEA and EFECT Trials.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020 10; 26(19):5172-5177. doi:
10.1158/1078-0432.ccr-20-0224. [PMID: 32546646] - Guangyi Leng, Yanhua Zuo, Jiahui Hu, Fei Yu, Wanhui Liu. Liquid chromatography tandem mass spectrometry method for determination of fulvestrant in rat plasma and its application to pharmacokinetic studies of a novel fulvestrant microcrystal.
Biomedical chromatography : BMC.
2020 Oct; 34(10):e4912. doi:
10.1002/bmc.4912. [PMID: 32496589] - Tsung-Jung Ho, Hsi Chin Wu, V Bharath Kumar, Wei-Wen Kuo, Yueh-Shan Weng, Yu-Lan Yeh, B Mahalakshmi, Cecilia Hsuan Day, Chi-Cheng Li, Chih-Yang Huang. Danshen (Salvia miltiorhiza) inhibits Leu27 IGF-II-induced hypertrophy in H9c2 cells.
Environmental toxicology.
2020 Oct; 35(10):1043-1049. doi:
10.1002/tox.22940. [PMID: 32415908] - Luc Cabel, Dan Rosenblum, Florence Lerebours, Etienne Brain, Delphine Loirat, Mattias Bergqvist, Paul Cottu, Anne Donnadieu, Anne Bethune, Nicolas Kiavue, Manuel Rodrigues, Jean-Yves Pierga, Marie-Laure Tanguy, François-Clément Bidard. Plasma thymidine kinase 1 activity and outcome of ER+ HER2- metastatic breast cancer patients treated with palbociclib and endocrine therapy.
Breast cancer research : BCR.
2020 09; 22(1):98. doi:
10.1186/s13058-020-01334-2. [PMID: 32928264] - H S Rugo, F André, T Yamashita, H Cerda, I Toledano, S M Stemmer, J C Jurado, D Juric, I Mayer, E M Ciruelos, H Iwata, P Conte, M Campone, C Wilke, D Mills, A Lteif, M Miller, F Gaudenzi, S Loibl. Time course and management of key adverse events during the randomized phase III SOLAR-1 study of PI3K inhibitor alpelisib plus fulvestrant in patients with HR-positive advanced breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology.
2020 08; 31(8):1001-1010. doi:
10.1016/j.annonc.2020.05.001. [PMID: 32416251] - Zongbi Yi, Binliang Liu, Xiaoying Sun, Guohua Rong, Wenna Wang, Hui Li, Xiuwen Guan, Lixi Li, Jingtong Zhai, Chunxiao Li, Haili Qian, Fei Ma, Binghe Xu. Safety and efficacy of sirolimus combined with endocrine therapy in patients with advanced hormone receptor-positive breast cancer and the exploration of biomarkers.
Breast (Edinburgh, Scotland).
2020 Aug; 52(?):17-22. doi:
10.1016/j.breast.2020.04.004. [PMID: 32335491] - Lillian M Smyth, Kenji Tamura, Mafalda Oliveira, Eva M Ciruelos, Ingrid A Mayer, Marie-Paule Sablin, Laura Biganzoli, Helen J Ambrose, Jack Ashton, Alan Barnicle, Des D Cashell, Claire Corcoran, Elza C de Bruin, Andrew Foxley, Joana Hauser, Justin P O Lindemann, Rhiannon Maudsley, Robert McEwen, Michele Moschetta, Martin Pass, Vicky Rowlands, Gaia Schiavon, Udai Banerji, Maurizio Scaltriti, Barry S Taylor, Sarat Chandarlapaty, José Baselga, David M Hyman. Capivasertib, an AKT Kinase Inhibitor, as Monotherapy or in Combination with Fulvestrant in Patients with AKT1 E17K-Mutant, ER-Positive Metastatic Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020 08; 26(15):3947-3957. doi:
10.1158/1078-0432.ccr-19-3953. [PMID: 32312891] - Sara M Tolaney, Andrew M Wardley, Stefania Zambelli, John F Hilton, Tiffany A Troso-Sandoval, Francesco Ricci, Seock-Ah Im, Sung-Bae Kim, Stephen Rd Johnston, Arlene Chan, Shom Goel, Kristen Catron, Sonya C Chapman, Gregory L Price, Zhengyu Yang, M Corona Gainford, Fabrice André. Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in women with hormone receptor-positive, HER2-positive advanced breast cancer (monarcHER): a randomised, open-label, phase 2 trial.
The Lancet. Oncology.
2020 06; 21(6):763-775. doi:
10.1016/s1470-2045(20)30112-1. [PMID: 32353342] - Ting Luan, Xia Liu, Pengyuan Mao, Xinyan Wang, Can Rui, Lina Yan, Yiquan Wang, Chong Fan, Ping Li, Xin Zeng. The Role of 17β-Estrogen in Candida albicans Adhesion on Human Vaginal Epithelial Cells via FAK Phosphorylation.
Mycopathologia.
2020 Jun; 185(3):425-438. doi:
10.1007/s11046-020-00440-1. [PMID: 32185617] - Mennatallah A Ali, Maher A Kamel. Modulation of the hepatic expression of miR-33 and miR-34a possibly mediates the metabolic effects of estrogen in ovariectomized female rats.
European journal of pharmacology.
2020 Apr; 873(?):173006. doi:
10.1016/j.ejphar.2020.173006. [PMID: 32045601] - Seon-Young Park, Yeong-Min Yoo, Eui-Man Jung, Eui-Bae Jeung. The effect of steroid hormone on the expression of the calcium-processing proteins in the immature female rat brain.
Journal of chemical neuroanatomy.
2020 04; 105(?):101767. doi:
10.1016/j.jchemneu.2020.101767. [PMID: 32061997] - Emmanuelle Jeannot, Lauren Darrigues, Marc Michel, Marc-Henri Stern, Jean-Yves Pierga, Aurore Rampanou, Samia Melaabi, Camille Benoist, Ivan Bièche, Anne Vincent-Salomon, Radouane El Ayachy, Aurélien Noret, Nicolas Epaillard, Luc Cabel, François-Clément Bidard, Charlotte Proudhon. A single droplet digital PCR for ESR1 activating mutations detection in plasma.
Oncogene.
2020 04; 39(14):2987-2995. doi:
10.1038/s41388-020-1174-y. [PMID: 32042112] - Allyssa Fahrenkopf, Christine K Wagner. Bisphenol A (BPA) induces progesterone receptor expression in an estrogen receptor α-dependent manner in perinatal brain.
Neurotoxicology and teratology.
2020 Mar; 78(?):106864. doi:
10.1016/j.ntt.2020.106864. [PMID: 31926947] - Robert H Jones, Angela Casbard, Margherita Carucci, Catrin Cox, Rachel Butler, Fouad Alchami, Tracie-Ann Madden, Catherine Bale, Pavel Bezecny, Johnathan Joffe, Sarah Moon, Chris Twelves, Ramachandran Venkitaraman, Simon Waters, Andrew Foxley, Sacha J Howell. Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial.
The Lancet. Oncology.
2020 03; 21(3):345-357. doi:
10.1016/s1470-2045(19)30817-4. [PMID: 32035020] - Prabin Dhangada Majhi, Aman Sharma, Amy L Roberts, Elizabeth Daniele, Aliza R Majewski, Lynn M Chuong, Amye L Black, Laura N Vandenberg, Sallie S Schneider, Karen A Dunphy, D Joseph Jerry. Effects of Benzophenone-3 and Propylparaben on Estrogen Receptor-Dependent R-Loops and DNA Damage in Breast Epithelial Cells and Mice.
Environmental health perspectives.
2020 01; 128(1):17002. doi:
10.1289/ehp5221. [PMID: 31939680] - Suzanne E Wardell, Alexander P Yllanes, Christina A Chao, Yeeun Bae, Kaitlyn J Andreano, Taylor K Desautels, Kendall A Heetderks, Jeremy T Blitzer, John D Norris, Donald P McDonnell. Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy.
Breast cancer research and treatment.
2020 Jan; 179(1):67-77. doi:
10.1007/s10549-019-05454-y. [PMID: 31562570] - Sayed M Abd El-Lateef, El-Sayed M El-Sayed, Ahmed M Mansour, Salama A Salama. The protective role of estrogen and its receptors in gentamicin-induced acute kidney injury in rats.
Life sciences.
2019 Dec; 239(?):117082. doi:
10.1016/j.lfs.2019.117082. [PMID: 31756345] - J Tyler Ramsey, Yin Li, Yukitomo Arao, Ajanta Naidu, Laurel A Coons, Alejandro Diaz, Kenneth S Korach. Lavender Products Associated With Premature Thelarche and Prepubertal Gynecomastia: Case Reports and Endocrine-Disrupting Chemical Activities.
The Journal of clinical endocrinology and metabolism.
2019 11; 104(11):5393-5405. doi:
10.1210/jc.2018-01880. [PMID: 31393563] - Liyue Qin, Ziyu Chen, Liu Yang, Hailian Shi, Hui Wu, Beibei Zhang, Weiqi Zhang, Qi Xu, Fei Huang, Xiaojun Wu. Luteolin-7-O-glucoside protects dopaminergic neurons by activating estrogen-receptor-mediated signaling pathway in MPTP-induced mice.
Toxicology.
2019 10; 426(?):152256. doi:
10.1016/j.tox.2019.152256. [PMID: 31381935] - Ye Feng, Yang Xie, Meishu Xu, Linhao Li, Kyle W Selcer, Patrick J Oberly, Samuel M Poloyac, Hongbing Wang, Chengjiang Li, Fengqin Dong, Chaohui Yu, Wen Xie. Hepatic steroid sulfatase critically determines estrogenic activities of conjugated equine estrogens in human cells in vitro and in mice.
The Journal of biological chemistry.
2019 08; 294(32):12112-12121. doi:
10.1074/jbc.ra119.009181. [PMID: 31217279] - Hui-Juan Cao, Cai-Rong Li, Lin-Ying Wang, Reihane Ziadlou, Sibylle Grad, Yan Zhang, Yan Cheng, Yu-Xiao Lai, Xin-Sheng Yao, Mauro Alini, Ling Qin, Xin-Luan Wang. Effect and mechanism of psoralidin on promoting osteogenesis and inhibiting adipogenesis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2019 Aug; 61(?):152860. doi:
10.1016/j.phymed.2019.152860. [PMID: 31048126] - Eric N Donders, Ahil N Ganesh, Hayarpi Torosyan, Parnian Lak, Brian K Shoichet, Molly S Shoichet. Triggered Release Enhances the Cytotoxicity of Stable Colloidal Drug Aggregates.
ACS chemical biology.
2019 07; 14(7):1507-1514. doi:
10.1021/acschembio.9b00247. [PMID: 31243955] - Lina Liu, Jing Yan, Fei Ge, Xiangtao Xu, Jun Lu, Huilian Shi, Shuihong Li, Yue Zhao, Changzheng Zhang. Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus.
Molecular medicine reports.
2019 Jul; 20(1):332-340. doi:
10.3892/mmr.2019.10232. [PMID: 31115535] - Xiaoqing Jia, Chunjie Li, Lihui Li, Xiaoli Liu, Lisha Zhou, Wenjuan Zhang, Shuaishuai Ni, Yun Lu, Li Chen, Lak Shin Jeong, Jinha Yu, Yingjian Zhang, Jianping Zhang, Simin He, Xin Hu, Hefen Sun, Keda Yu, Guangyu Liu, Hu Zhao, Yanmei Zhang, Lijun Jia, Zhi-Ming Shao. Neddylation Inactivation Facilitates FOXO3a Nuclear Export to Suppress Estrogen Receptor Transcription and Improve Fulvestrant Sensitivity.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019 06; 25(12):3658-3672. doi:
10.1158/1078-0432.ccr-18-2434. [PMID: 30833270] - Noriko Kanaya, Lauren Bernal, Gregory Chang, Takuro Yamamoto, Duc Nguyen, Yuan-Zhong Wang, June-Soo Park, Charles Warden, Jinhui Wang, Xiwei Wu, Timothy Synold, Michele Rakoff, Susan L Neuhausen, Shiuan Chen. Molecular Mechanisms of Polybrominated Diphenyl Ethers (BDE-47, BDE-100, and BDE-153) in Human Breast Cancer Cells and Patient-Derived Xenografts.
Toxicological sciences : an official journal of the Society of Toxicology.
2019 06; 169(2):380-398. doi:
10.1093/toxsci/kfz054. [PMID: 30796839] - Amelia McCartney, Chiara Biagioni, Gaia Schiavon, Mattias Bergqvist, Karin Mattsson, Ilenia Migliaccio, Matteo Benelli, Dario Romagnoli, Martina Bonechi, Giulia Boccalini, Marta Pestrin, Francesca Galardi, Francesca De Luca, Laura Biganzoli, Martine Piccart, William J Gradishar, Stephen Chia, Angelo Di Leo, Luca Malorni. Prognostic role of serum thymidine kinase 1 activity in patients with hormone receptor-positive metastatic breast cancer: Analysis of the randomised phase III Evaluation of Faslodex versus Exemestane Clinical Trial (EFECT).
European journal of cancer (Oxford, England : 1990).
2019 06; 114(?):55-66. doi:
10.1016/j.ejca.2019.04.002. [PMID: 31059974] - Ahil N Ganesh, Ahmed Aman, Jennifer Logie, Ben L Barthel, Peter Cogan, Rima Al-Awar, Tad H Koch, Brian K Shoichet, Molly S Shoichet. Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence.
ACS chemical biology.
2019 04; 14(4):751-757. doi:
10.1021/acschembio.9b00032. [PMID: 30840432] - Laura J Owen, Phillip J Monaghan, Anne Armstrong, Brian G Keevil, Claire Higham, Zena Salih, Sacha Howell. Oestradiol measurement during fulvestrant treatment for breast cancer.
British journal of cancer.
2019 02; 120(4):404-406. doi:
10.1038/s41416-019-0378-9. [PMID: 30679781] - Liliana Del V Sosa, Juan P Petiti, Florencia Picech, Sabrina Chumpen, Juan P Nicola, Pablo Perez, Ana De Paul, Javier Valdez-Taubas, Silvina Gutierrez, Alicia I Torres. The ERα membrane pool modulates the proliferation of pituitary tumours.
The Journal of endocrinology.
2019 02; 240(2):229-241. doi:
10.1530/joe-18-0418. [PMID: 30400032] - Qi Zhang, Shuang Wu, Lu Liu, Xiaohong Hou, Jianjun Jiang, Xuetao Wei, Weidong Hao. Effects of bisphenol A on gap junctions in HaCaT cells as mediated by the estrogen receptor pathway.
Journal of applied toxicology : JAT.
2019 02; 39(2):271-281. doi:
10.1002/jat.3717. [PMID: 30187510] - Xi-Dan Zhou, Yu Zheng, Rakesh Sharma, Zhang-Jin Zhang. Total Polysaccharides of Lily Bulb Ameliorate Menopause-Like Behavior in Ovariectomized Mice: Multiple Mechanisms Distinct from Estrogen Therapy.
Oxidative medicine and cellular longevity.
2019; 2019(?):6869350. doi:
10.1155/2019/6869350. [PMID: 31428228] - Wenbin Song, Dalin He, Yule Chen, Chiuan-Ren Yeh, Iawen Hsu, Qingbo Huang, Xu Zhang, Luke Sien-Shih Chang, Li Zuo, Jiasheng Chen, Karen M Doersch, Chawnshang Chang, Lei Li, Shuyuan Yeh. Targeting newly identified ERβ/TGF-β1/SMAD3 signals with the FDA-approved anti-estrogen Faslodex or an ERβ selective antagonist in renal cell carcinoma.
Molecular oncology.
2018 12; 12(12):2055-2071. doi:
10.1002/1878-0261.12377. [PMID: 30171816] - Xu Liang, Adrien Briaux, Véronique Becette, Camille Benoist, Anais Boulai, Walid Chemlali, Anne Schnitzler, Sylvain Baulande, Sofia Rivera, Marie-Ange Mouret-Reynier, Laurence Venat Bouvet, Thibaut De La Motte Rouge, Jérôme Lemonnier, Florence Lerebours, Céline Callens. Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609).
Journal of hematology & oncology.
2018 10; 11(1):124. doi:
10.1186/s13045-018-0670-9. [PMID: 30305115] - Samantha Medwid, Haiyan Guan, Kaiping Yang. Bisphenol A stimulates steroidogenic acute regulatory protein expression via an unknown mechanism in adrenal cortical cells.
Journal of cellular biochemistry.
2018 Sep; ?(?):. doi:
10.1002/jcb.27574. [PMID: 30206973] - Dinh Nam Tran, Eui-Man Jung, Changhwan Ahn, Jae-Hwan Lee, Yeong-Min Yoo, Eui-Bae Jeung. Effects of Bisphenol A and 4-tert-Octylphenol on Embryo Implantation Failure in Mouse.
International journal of environmental research and public health.
2018 07; 15(8):. doi:
10.3390/ijerph15081614. [PMID: 30061528] - Thomas L Gonzalez, Rebecca K Moos, Christina L Gersch, Michael D Johnson, Rudy J Richardson, Holger M Koch, James M Rae. Metabolites of n-Butylparaben and iso-Butylparaben Exhibit Estrogenic Properties in MCF-7 and T47D Human Breast Cancer Cell Lines.
Toxicological sciences : an official journal of the Society of Toxicology.
2018 07; 164(1):50-59. doi:
10.1093/toxsci/kfy063. [PMID: 29945225] - Katarzyna Knapczyk-Stwora, Malgorzata Grzesiak, Renata E Ciereszko, Elzbieta Czaja, Marek Koziorowski, Maria Slomczynska. The impact of sex steroid agonists and antagonists on folliculogenesis in the neonatal porcine ovary via cell proliferation and apoptosis.
Theriogenology.
2018 Jun; 113(?):19-26. doi:
10.1016/j.theriogenology.2018.02.008. [PMID: 29452853] - Dandan Xia, Huiyu Wang, Runjie Wang, Chaoying Liu, Junying Xu. High-dose fulvestrant as third-line endocrine therapy for breast cancer metastasis to the left kidney: A case report and literature review.
Medicine.
2018 Jun; 97(24):e11115. doi:
10.1097/md.0000000000011115. [PMID: 29901634] - Dahae Lee, SeonJu Park, Sungyoul Choi, Seung Hyun Kim, Ki Sung Kang. In Vitro Estrogenic and Breast Cancer Inhibitory Activities of Chemical Constituents Isolated from Rheum undulatum L.
Molecules (Basel, Switzerland).
2018 May; 23(5):. doi:
10.3390/molecules23051215. [PMID: 29783719] - Anika Engel, Thorsten Buhrke, Stefanie Kasper, Anne-Cathrin Behr, Albert Braeuning, Sönke Jessel, Albrecht Seidel, Wolfgang Völkel, Alfonso Lampen. The urinary metabolites of DINCH® have an impact on the activities of the human nuclear receptors ERα, ERβ, AR, PPARα and PPARγ.
Toxicology letters.
2018 May; 287(?):83-91. doi:
10.1016/j.toxlet.2018.02.006. [PMID: 29421333] - Mu Yuan, Minhao Hu, Yiyun Lou, Qijing Wang, Luna Mao, Qitao Zhan, Fan Jin. Environmentally relevant levels of bisphenol A affect uterine decidualization and embryo implantation through the estrogen receptor/serum and glucocorticoid-regulated kinase 1/epithelial sodium ion channel α-subunit pathway in a mouse model.
Fertility and sterility.
2018 04; 109(4):735-744.e1. doi:
10.1016/j.fertnstert.2017.12.003. [PMID: 29605410] - Ben O'Leary, Sarah Hrebien, James P Morden, Matthew Beaney, Charlotte Fribbens, Xin Huang, Yuan Liu, Cynthia Huang Bartlett, Maria Koehler, Massimo Cristofanilli, Isaac Garcia-Murillas, Judith M Bliss, Nicholas C Turner. Early circulating tumor DNA dynamics and clonal selection with palbociclib and fulvestrant for breast cancer.
Nature communications.
2018 03; 9(1):896. doi:
10.1038/s41467-018-03215-x. [PMID: 29497091] - Wenhui Qiu, Ming Yang, Shuai Liu, Penghui Lei, Lei Hu, Bei Chen, Minghong Wu, Ke-Jian Wang. Toxic Effects of Bisphenol S Showing Immunomodulation in Fish Macrophages.
Environmental science & technology.
2018 01; 52(2):831-838. doi:
10.1021/acs.est.7b04226. [PMID: 29261303] - B-Z Zheng, T-D Liu, G Chen, J-X Zhang, X Kang. The effect of curcumin on cell adhesion of human esophageal cancer cell.
European review for medical and pharmacological sciences.
2018 01; 22(2):551-560. doi:
10.26355/eurrev_201801_14209. [PMID: 29424917] - Virginia Rider, Nabih I Abdou, Bruce F Kimler, Nanyan Lu, Susan Brown, Brooke L Fridley. Gender Bias in Human Systemic Lupus Erythematosus: A Problem of Steroid Receptor Action?.
Frontiers in immunology.
2018; 9(?):611. doi:
10.3389/fimmu.2018.00611. [PMID: 29643853] - YongHong Zhang, Feng Wei, Jing Zhang, Lanxiang Hao, Jie Jiang, Liansheng Dang, Dan Mei, ShanShan Fan, Yajin Yu, Ling Jiang. Bisphenol A and estrogen induce proliferation of human thyroid tumor cells via an estrogen-receptor-dependent pathway.
Archives of biochemistry and biophysics.
2017 11; 633(?):29-39. doi:
10.1016/j.abb.2017.09.002. [PMID: 28882636] - Kenichi Sakurai, Shigeru Fujisaki, Hitomi Kubota, Yukiko Hara, Shuhei Suzuki, Keita Adachi, Ryouichi Tomita, Katsuhisa Enomoto, Tomohiro Hirano, Reina Saga, Makoto Makishima. [Indoleamine 2,3-Dioxygenase Activity during Fulvestrant Therapy for Aromatase Inhibitor Resistant Metastatic Breast Cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
2017 Oct; 44(10):886-888. doi:
NULL. [PMID: 29066685] - Ya-Wen Chen, Kuo-Cheng Lan, Jing-Ren Tsai, Te-I Weng, Ching-Yao Yang, Shing-Hwa Liu. Tributyltin exposure at noncytotoxic doses dysregulates pancreatic β-cell function in vitro and in vivo.
Archives of toxicology.
2017 Sep; 91(9):3135-3144. doi:
10.1007/s00204-017-1940-y. [PMID: 28180948] - Sibylle Loibl, Nicholas C Turner, Jungsil Ro, Massimo Cristofanilli, Hiroji Iwata, Seock-Ah Im, Norikazu Masuda, Sherene Loi, Fabrice André, Nadia Harbeck, Sunil Verma, Elizabeth Folkerd, Kathy Puyana Theall, Justin Hoffman, Ke Zhang, Cynthia Huang Bartlett, Mitchell Dowsett. Palbociclib Combined with Fulvestrant in Premenopausal Women with Advanced Breast Cancer and Prior Progression on Endocrine Therapy: PALOMA-3 Results.
The oncologist.
2017 09; 22(9):1028-1038. doi:
10.1634/theoncologist.2017-0072. [PMID: 28652278] - Anika Engel, Thorsten Buhrke, Francine Imber, Sönke Jessel, Albrecht Seidel, Wolfgang Völkel, Alfonso Lampen. Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR.
Toxicology letters.
2017 Aug; 277(?):54-63. doi:
10.1016/j.toxlet.2017.05.028. [PMID: 28571686] - Qiong Lv, Rufei Gao, Chuan Peng, Juan Yi, Lulu Liu, Shumin Yang, Danting Li, Jinbo Hu, Ting Luo, Mei Mei, Ying Song, Chaodong Wu, Xiaoqiu Xiao, Qifu Li. Bisphenol A promotes hepatic lipid deposition involving Kupffer cells M1 polarization in male mice.
The Journal of endocrinology.
2017 Aug; 234(2):143-154. doi:
10.1530/joe-17-0028. [PMID: 28500084] - Kipung Kim, Dongoh Lee, Changhwan Ahn, Hee Young Kang, Beum-Soo An, Yeon Hee Seong, Eui-Bae Jeung. Effects of estrogen on esophageal function through regulation of Ca2+-related proteins.
Journal of gastroenterology.
2017 Aug; 52(8):929-939. doi:
10.1007/s00535-016-1305-y. [PMID: 28078471] - Xinping Chen, Eric D Austin, Megha Talati, Joshua P Fessel, Eric H Farber-Eger, Evan L Brittain, Anna R Hemnes, James E Loyd, James West. Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects.
The European respiratory journal.
2017 08; 50(2):. doi:
10.1183/13993003.02337-2016. [PMID: 28775043] - Zhansheng Wang, Minkun Shao, Yulu Liu. Promotion of Wilms' tumor cells migration and invasion by mono-2-ethyhexyl phthalate (MEHP) via activation of NF-κB signals.
Chemico-biological interactions.
2017 May; 270(?):1-8. doi:
10.1016/j.cbi.2017.04.004. [PMID: 28390675] - Rinath Jeselsohn, Carmine De Angelis, Myles Brown, Rachel Schiff. The Evolving Role of the Estrogen Receptor Mutations in Endocrine Therapy-Resistant Breast Cancer.
Current oncology reports.
2017 May; 19(5):35. doi:
10.1007/s11912-017-0591-8. [PMID: 28374222] - Ahil N Ganesh, Christopher K McLaughlin, Da Duan, Brian K Shoichet, Molly S Shoichet. A New Spin on Antibody-Drug Conjugates: Trastuzumab-Fulvestrant Colloidal Drug Aggregates Target HER2-Positive Cells.
ACS applied materials & interfaces.
2017 Apr; 9(14):12195-12202. doi:
10.1021/acsami.6b15987. [PMID: 28319364] - Nathan Long, Bertha Long, Asma Mana, Dream Le, Lam Nguyen, Sima Chokr, Kevin Sinchak. Tamoxifen and ICI 182,780 activate hypothalamic G protein-coupled estrogen receptor 1 to rapidly facilitate lordosis in female rats.
Hormones and behavior.
2017 03; 89(?):98-103. doi:
10.1016/j.yhbeh.2016.12.013. [PMID: 28063803] - Rui-Yun Bi, Zhen Meng, Peng Zhang, Xue-Dong Wang, Yun Ding, Ye-Hua Gan. Estradiol upregulates voltage-gated sodium channel 1.7 in trigeminal ganglion contributing to hyperalgesia of inflamed TMJ.
PloS one.
2017; 12(6):e0178589. doi:
10.1371/journal.pone.0178589. [PMID: 28582470] - Ying Xu, Ting Chen, Xin Li, Ya-Kun Qu, Jin-Na An, Hong-Xia Zheng, Zi-Jia Zhang, Na Lin. Salvia miltiorrhiza bunge increases estrogen level without side effects on reproductive tissues in immature/ovariectomized mice.
Aging.
2016 12; 9(1):156-172. doi:
10.18632/aging.101145. [PMID: 27997360] - Karen E Weis, Lori T Raetzman. Isoliquiritigenin exhibits anti-proliferative properties in the pituitary independent of estrogen receptor function.
Toxicology and applied pharmacology.
2016 Dec; 313(?):204-214. doi:
10.1016/j.taap.2016.09.027. [PMID: 27702603] - C Mayer, M Adam, L Glashauser, K Dietrich, J U Schwarzer, F-M Köhn, L Strauss, H Welter, M Poutanen, A Mayerhofer. Sterile inflammation as a factor in human male infertility: Involvement of Toll like receptor 2, biglycan and peritubular cells.
Scientific reports.
2016 11; 6(?):37128. doi:
10.1038/srep37128. [PMID: 27849015] - Kenichi Sakurai, Shigeru Fujisaki, Keita Adachi, Shuhei Suzuki, Yuki Masuo, Saki Nagashima, Yukiko Hara, Tomohiro Hirano, Katsuhisa Enomoto, Ryouichi Tomita, Kenji Gonda. [Indoleamine 2,3-Dioxygenase Activity during Fulvestrant Therapy for Multiple Metastatic Breast Cancer Patients].
Gan to kagaku ryoho. Cancer & chemotherapy.
2016 Oct; 43(10):1233-1236. doi:
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Scientific reports.
2016 09; 6(?):32105. doi:
10.1038/srep32105. [PMID: 27601313] - Charlotte Fribbens, Ben O'Leary, Lucy Kilburn, Sarah Hrebien, Isaac Garcia-Murillas, Matthew Beaney, Massimo Cristofanilli, Fabrice Andre, Sherene Loi, Sibylle Loibl, John Jiang, Cynthia Huang Bartlett, Maria Koehler, Mitch Dowsett, Judith M Bliss, Stephen R D Johnston, Nicholas C Turner. Plasma ESR1 Mutations and the Treatment of Estrogen Receptor-Positive Advanced Breast Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016 09; 34(25):2961-8. doi:
10.1200/jco.2016.67.3061. [PMID: 27269946] - Haruo Nogami, Yoshiki Hiraoka, Sadakazu Aiso. Estradiol and corticosterone stimulate the proliferation of a GH cell line, MtT/S: Proliferation of growth hormone cells.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
2016 08; 29(?):33-38. doi:
10.1016/j.ghir.2016.03.006. [PMID: 27082452] - Norbert Nass, Angela Dittmer, Vicky Hellwig, Theresia Lange, Johanna Mirjam Beyer, Benjamin Leyh, Atanas Ignatov, Christine Weiβenborn, Tove Kirkegaard, Anne E Lykkesfeldt, Thomas Kalinski, Jürgen Dittmer. Expression of transmembrane protein 26 (TMEM26) in breast cancer and its association with drug response.
Oncotarget.
2016 Jun; 7(25):38408-38426. doi:
10.18632/oncotarget.9493. [PMID: 27224909] - Wei Yang, Sarah R Hosford, Lloye M Dillon, Kevin Shee, Stephanie C Liu, Jennifer R Bean, Laurent Salphati, Jodie Pang, Xiaolin Zhang, Michelle A Nannini, Eugene Demidenko, Darcy Bates, Lionel D Lewis, Jonathan D Marotti, Alan R Eastman, Todd W Miller. Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha-Positive, PIK3CA-Mutant Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016 05; 22(9):2250-60. doi:
10.1158/1078-0432.ccr-15-2276. [PMID: 26733612] - Giorgio Biasiotto, Isabella Zanella, Alice Masserdotti, Roberta Pedrazzani, Matteo Papa, Luigi Caimi, Diego Di Lorenzo. Municipal wastewater affects adipose deposition in male mice and increases 3T3-L1 cell differentiation.
Toxicology and applied pharmacology.
2016 Apr; 297(?):32-40. doi:
10.1016/j.taap.2016.02.023. [PMID: 26944108] - Kristin M Bircsak, Vivek Gupta, Poi Yu Sofia Yuen, Ludwik Gorczyca, Barry I Weinberger, Anna M Vetrano, Lauren M Aleksunes. Genetic and Dietary Regulation of Glyburide Efflux by the Human Placental Breast Cancer Resistance Protein Transporter.
The Journal of pharmacology and experimental therapeutics.
2016 Apr; 357(1):103-13. doi:
10.1124/jpet.115.230185. [PMID: 26850786] - Jonathan G Boucher, Shaimaa Ahmed, Ella Atlas. Bisphenol S Induces Adipogenesis in Primary Human Preadipocytes From Female Donors.
Endocrinology.
2016 Apr; 157(4):1397-407. doi:
10.1210/en.2015-1872. [PMID: 27003841] - Cynthia X Ma, Jingqin Luo, Michael Naughton, Foluso Ademuyiwa, Rama Suresh, Malachi Griffith, Obi L Griffith, Zachary L Skidmore, Nicholas C Spies, Avinash Ramu, Lee Trani, Timothy Pluard, Gayathri Nagaraj, Shana Thomas, Zhanfang Guo, Jeremy Hoog, Jing Han, Elaine Mardis, Craig Lockhart, Matthew J Ellis. A Phase I Trial of BKM120 (Buparlisib) in Combination with Fulvestrant in Postmenopausal Women with Estrogen Receptor-Positive Metastatic Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2016 Apr; 22(7):1583-91. doi:
10.1158/1078-0432.ccr-15-1745. [PMID: 26563128] - Laura Hayes, Allison Weening, Lisa M Morey. Differential Effects of Estradiol and Bisphenol A on SET8 and SIRT1 Expression in Ovarian Cancer Cells.
Dose-response : a publication of International Hormesis Society.
2016 Apr; 14(2):1559325816640682. doi:
10.1177/1559325816640682. [PMID: 27114721] - Massimo Cristofanilli, Nicholas C Turner, Igor Bondarenko, Jungsil Ro, Seock-Ah Im, Norikazu Masuda, Marco Colleoni, Angela DeMichele, Sherene Loi, Sunil Verma, Hiroji Iwata, Nadia Harbeck, Ke Zhang, Kathy Puyana Theall, Yuqiu Jiang, Cynthia Huang Bartlett, Maria Koehler, Dennis Slamon. Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial.
The Lancet. Oncology.
2016 Apr; 17(4):425-439. doi:
10.1016/s1470-2045(15)00613-0. [PMID: 26947331] - Chantal B Bartels, Kamaria C Cayton, Farah S Chuong, Kristine Holthouser, Sara E Arian, Tara Abraham, James H Segars. An Evidence-based Approach to the Medical Management of Fibroids: A Systematic Review.
Clinical obstetrics and gynecology.
2016 03; 59(1):30-52. doi:
10.1097/grf.0000000000000171. [PMID: 26756261] - Jiaqiang Zhang, Changqing Xu, Dyanet L Puentes, Christoph N Seubert, Nikolaus Gravenstein, Anatoly E Martynyuk. Role of Steroids in Hyperexcitatory Adverse and Anesthetic Effects of Sevoflurane in Neonatal Rats.
Neuroendocrinology.
2016; 103(5):440-51. doi:
10.1159/000437267. [PMID: 26159049] - Jonathan G Boucher, Adèle Boudreau, Shaimaa Ahmed, Ella Atlas. In Vitro Effects of Bisphenol A β-D-Glucuronide (BPA-G) on Adipogenesis in Human and Murine Preadipocytes.
Environmental health perspectives.
2015 Dec; 123(12):1287-93. doi:
10.1289/ehp.1409143. [PMID: 26018136] - Xin Wang, Jun Liu, Zi Long, Quangui Sun, Ying Liu, Lele Wang, Xiaodi Zhang, Chunxu Hai. Effect of diosgenin on metabolic dysfunction: Role of ERβ in the regulation of PPARγ.
Toxicology and applied pharmacology.
2015 Dec; 289(2):286-96. doi:
10.1016/j.taap.2015.09.015. [PMID: 26408789] - Na Huang, Bo Liu, Zhiheng Dong, Wei Mao, Nan Zhang, Changyou Li, Jinshan Cao. Prostanoid receptors EP2, EP4, and FP are regulated by estradiol in bovine oviductal smooth muscle.
Prostaglandins & other lipid mediators.
2015 Sep; 121(Pt B):170-5. doi:
10.1016/j.prostaglandins.2015.08.002. [PMID: 26319698]