Monobenzyl phthalate (BioDeep_00000398407)

Industrial Pollutants

代谢物信息卡片

Monobenzyl phthalate

化学式: C15H12O4 (256.0736)
中文名称: 邻苯二甲酸单苄酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)COC(=O)C2=CC=CC=C2C(=O)O
InChI: InChI=1S/C15H12O4/c16-14(17)12-8-4-5-9-13(12)15(18)19-10-11-6-2-1-3-7-11/h1-9H,10H2,(H,16,17)

描述信息

A phthalic acid monoester resulting from the formal condensation of one of the carboxy groups of phthalic acid with the hydroxy group of benzyl alcohol. It is a major metabolite of the plasticiser butyl benzyl phthalate (BBP).
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4406; ORIGINAL_PRECURSOR_SCAN_NO 4401
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4408; ORIGINAL_PRECURSOR_SCAN_NO 4407
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4373; ORIGINAL_PRECURSOR_SCAN_NO 4371
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4400; ORIGINAL_PRECURSOR_SCAN_NO 4398
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4390; ORIGINAL_PRECURSOR_SCAN_NO 4386
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4386; ORIGINAL_PRECURSOR_SCAN_NO 4385
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8673; ORIGINAL_PRECURSOR_SCAN_NO 8669
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8702; ORIGINAL_PRECURSOR_SCAN_NO 8699
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8754; ORIGINAL_PRECURSOR_SCAN_NO 8751
CONFIDENCE standard compound; INTERNAL_ID 729; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8770; ORIGINAL_PRECURSOR_SCAN_NO 8765
CONFIDENCE standard compound; INTERNAL_ID 8231
CONFIDENCE standard compound; INTERNAL_ID 4204

同义名列表

2 个代谢物同义名

Monobenzyl phthalate; MBzPA

数据库引用编号

26 个数据库交叉引用编号

ChEBI: CHEBI:132612
PubChem: 31736
ChEMBL: CHEMBL1466083
CAS: 2528-16-7
MoNA: LU072956
MoNA: LU072955
MoNA: LU072954
MoNA: LU072953
MoNA: LU072952
MoNA: LU072951
MoNA: LU072906
MoNA: LU072905
MoNA: LU072903
MoNA: LU072901
MoNA: SM823154
MoNA: SM823104
MoNA: UF420454
MoNA: UF420453
MoNA: UF420452
MoNA: UF420451
MoNA: UF420404
MoNA: UF420403
MoNA: UF420402
MoNA: UF420401
MetaboLights: MTBLC132612
RefMet: Monobenzyl phthalate

分类词条

Phthalate esters

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位		关联基因列表

文献列表

Qingqing Zhu, Jian Hou, Wenjun Yin, Fang Ye, Tian Xu, Juan Cheng, Zhiqiang Yu, Lin Wang, Jing Yuan. Associations of a mixture of urinary phthalate metabolites with blood lipid traits: A repeated-measures pilot study. Environmental pollution (Barking, Essex : 1987). 2020 Feb; 257(?):113509. doi: 10.1016/j.envpol.2019.113509. [PMID: 31767236]
Anna Mentor, Björn Brunström, Anna Mattsson, Maria Jönsson. Developmental exposure to a human relevant mixture of endocrine disruptors alters metabolism and adipogenesis in zebrafish (Danio rerio). Chemosphere. 2020 Jan; 238(?):124584. doi: 10.1016/j.chemosphere.2019.124584. [PMID: 31470313]
Garthika Navaranjan, Tim K Takaro, Amanda J Wheeler, Miriam L Diamond, Huan Shu, Meghan B Azad, Allan B Becker, Ruixue Dai, Shelley A Harris, Diana L Lefebvre, Zihang Lu, Piush J Mandhane, Kathleen McLean, Theo J Moraes, James A Scott, Stuart E Turvey, Malcolm R Sears, Padmaja Subbarao, Jeffrey R Brook. Early life exposure to phthalates in the Canadian Healthy Infant Longitudinal Development (CHILD) study: a multi-city birth cohort. Journal of exposure science & environmental epidemiology. 2020 01; 30(1):70-85. doi: 10.1038/s41370-019-0182-x. [PMID: 31641275]
Vladimíra Puklová, Tomáš Janoš, Lenka Sochorová, Adam Vavrouš, Karel Vrbík, Alena Fialová, Lenka Hanzlíková, Milena Černá. Exposure to Mixed Phthalates in Czech Preschool and School Children. Archives of environmental contamination and toxicology. 2019 Nov; 77(4):471-479. doi: 10.1007/s00244-019-00645-6. [PMID: 31214748]
Yao Lv, Yaoyao Dong, Yiyan Wang, Qiqi Zhu, Linxi Li, Xiaoheng Li, Zhenkun Lin, Lihua Fan, Ren-Shan Ge. Benzyl butyl phthalate non-linearly affects rat Leydig cell development during puberty. Toxicology letters. 2019 Oct; 314(?):53-62. doi: 10.1016/j.toxlet.2019.07.016. [PMID: 31319113]
Yoonjeong Choi, Sun Ju Lee, Jooeun Jeon, Keum Ji Jung, Sun Ha Jee. Inverse associations of bisphenol A and phthalate metabolites with serum bilirubin levels in Korean population. Environmental science and pollution research international. 2019 Sep; 26(26):26685-26695. doi: 10.1007/s11356-019-05205-y. [PMID: 31292880]
Miriany Avelino Moreira Fernandez, Zenilda Lourdes Cardeal, Márcia Mendonça Carneiro, Leiliane Coelho André. Study of possible association between endometriosis and phthalate and bisphenol A by biomarkers analysis. Journal of pharmaceutical and biomedical analysis. 2019 Aug; 172(?):238-242. doi: 10.1016/j.jpba.2019.04.048. [PMID: 31063881]
Anastasia Repouskou, Emily Panagiotidou, Lydia Panagopoulou, Pernilla Larsdotter Bisting, Astrud R Tuck, Marcus O D Sjödin, Johan Lindberg, Evangelos Bozas, Joëlle Rüegg, Chris Gennings, Carl-Gustaf Bornehag, Pauliina Damdimopoulou, Antonios Stamatakis, Efthymia Kitraki. Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes. Scientific reports. 2019 04; 9(1):6424. doi: 10.1038/s41598-019-42377-6. [PMID: 31015488]
Jijun Shang, Jeanne Corriveau, Alexandre Champoux-Jenane, Julie Gagnon, Emmanuel Moss, Pierre Dumas, Eric Gaudreau, Jonathan Chevrier, Lorraine E Chalifour. Recovery From a Myocardial Infarction Is Impaired in Male C57bl/6 N Mice Acutely Exposed to the Bisphenols and Phthalates That Escape From Medical Devices Used in Cardiac Surgery. Toxicological sciences : an official journal of the Society of Toxicology. 2019 03; 168(1):78-94. doi: 10.1093/toxsci/kfy276. [PMID: 30398665]
Susanna D Mitro, MyDzung T Chu, Robin E Dodson, Gary Adamkiewicz, Lucy Chie, Florence M Brown, Tamarra M James-Todd. Phthalate metabolite exposures among immigrants living in the United States: findings from NHANES, 1999-2014. Journal of exposure science & environmental epidemiology. 2019 01; 29(1):71-82. doi: 10.1038/s41370-018-0029-x. [PMID: 29572484]
Xiaojie Sun, Jiufeng Li, Shuna Jin, Yuanyuan Li, Wenyu Liu, Hongzhi Zhao, Yanqiu Zhou, Yangqian Jiang, Hongxiu Liu, Wei Xia, Zongwei Cai, Shunqing Xu, Xiantao Shen. Associations between repeated measures of maternal urinary phthalate metabolites during pregnancy and cord blood glucocorticoids. Environment international. 2018 12; 121(Pt 1):471-479. doi: 10.1016/j.envint.2018.09.037. [PMID: 30278310]
Prajakta Parag Pednekar, Rahul Krishnaji Gajbhiye, Anushree D Patil, Suchitra Vishwambhar Surve, Ajit Ganesh Datar, Geetha Dharmesh Balsarkar, Anahita R Chuahan, Geeta Ramesh Vanage. Estimation of plasma levels of bisphenol-A & phthalates in fertile & infertile women by gas chromatography-mass spectrometry. The Indian journal of medical research. 2018 Dec; 148(6):734-742. doi: 10.4103/ijmr.ijmr_2077_16. [PMID: 30778008]
Paulina Sicińska. Di-n-butyl phthalate, butylbenzyl phthalate and their metabolites induce haemolysis and eryptosis in human erythrocytes. Chemosphere. 2018 Jul; 203(?):44-53. doi: 10.1016/j.chemosphere.2018.03.161. [PMID: 29605748]
Kyung-Shin Lee, Youn-Hee Lim, Kyoung-Nam Kim, Yoon-Hyeong Choi, Yun-Chul Hong, Nami Lee. Urinary phthalate metabolites concentrations and symptoms of depression in an elderly population. The Science of the total environment. 2018 Jun; 625(?):1191-1197. doi: 10.1016/j.scitotenv.2017.12.219. [PMID: 29996415]
Ronit Machtinger, Jia Zhong, Abdallah Mansur, Michal Adir, Catherine Racowsky, Russ Hauser, Kasey Brennan, Oskar Karlsson, Andrea A Baccarelli. Placental lncRNA Expression Is Associated With Prenatal Phthalate Exposure. Toxicological sciences : an official journal of the Society of Toxicology. 2018 05; 163(1):116-122. doi: 10.1093/toxsci/kfy013. [PMID: 29385630]
Jennifer J Adibi, Yaqi Zhao, Lei V Zhan, Mirhan Kapidzic, Nicholas Larocque, Hannu Koistinen, Ilpo T Huhtaniemi, Ulf-Håkan Stenman. An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells. Environmental health perspectives. 2017 10; 125(10):107010. doi: 10.1289/ehp1539. [PMID: 29089286]
Anika Engel, Thorsten Buhrke, Francine Imber, Sönke Jessel, Albrecht Seidel, Wolfgang Völkel, Alfonso Lampen. Agonistic and antagonistic effects of phthalates and their urinary metabolites on the steroid hormone receptors ERα, ERβ, and AR. Toxicology letters. 2017 Aug; 277(?):54-63. doi: 10.1016/j.toxlet.2017.05.028. [PMID: 28571686]
Deborah J Watkins, Brisa N Sánchez, Martha Maria Téllez-Rojo, Joyce M Lee, Adriana Mercado-García, Clara Blank-Goldenberg, Karen E Peterson, John D Meeker. Impact of phthalate and BPA exposure during in utero windows of susceptibility on reproductive hormones and sexual maturation in peripubertal males. Environmental health : a global access science source. 2017 06; 16(1):69. doi: 10.1186/s12940-017-0278-5. [PMID: 28637469]
Jennifer J Adibi, Jessie P Buckley, Myoung Keun Lee, Paige L Williams, Allan C Just, Yaqi Zhao, Hari K Bhat, Robin M Whyatt. Maternal urinary phthalates and sex-specific placental mRNA levels in an urban birth cohort. Environmental health : a global access science source. 2017 04; 16(1):35. doi: 10.1186/s12940-017-0241-5. [PMID: 28381288]
Maribel Casas, Damaskini Valvi, Ana Ballesteros-Gomez, Mireia Gascon, Mariana F Fernández, Raquel Garcia-Esteban, Carmen Iñiguez, David Martínez, Mario Murcia, Nuria Monfort, Noelia Luque, Soledad Rubio, Rosa Ventura, Jordi Sunyer, Martine Vrijheid. Exposure to Bisphenol A and Phthalates during Pregnancy and Ultrasound Measures of Fetal Growth in the INMA-Sabadell Cohort. Environmental health perspectives. 2016 Apr; 124(4):521-8. doi: 10.1289/ehp.1409190. [PMID: 26196298]
Yue Yang, Mingming Shi, Biqin Chen, Jianfeng Lin, Songjing Yang, Baoping Zhu, Baoling Zhuang, Yuzhu Jia, Zhenxiang Huang, Jing Chen, Huifen Liu, Jianghui Chen, Yanhua Su, Xiayi Ke, Benhua Zhao. [Levels of phthalate internal exposure levels in pregnant women and influencing factors]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. 2015 Nov; 49(11):998-1004. doi: NULL. [PMID: 26833012]
Candace A Robledo, Jennifer D Peck, Julie Stoner, Antonia M Calafat, Hélène Carabin, Linda Cowan, Jean R Goodman. Urinary phthalate metabolite concentrations and blood glucose levels during pregnancy. International journal of hygiene and environmental health. 2015 May; 218(3):324-30. doi: 10.1016/j.ijheh.2015.01.005. [PMID: 25726127]
Han-Bin Huang, Hsin-Yi Chen, Pen-Hua Su, Po-Chin Huang, Chien-Wen Sun, Chien-Jen Wang, Hsiao-Yen Chen, Chao A Hsiung, Shu-Li Wang. Fetal and Childhood Exposure to Phthalate Diesters and Cognitive Function in Children Up to 12 Years of Age: Taiwanese Maternal and Infant Cohort Study. PloS one. 2015; 10(6):e0131910. doi: 10.1371/journal.pone.0131910. [PMID: 26121592]
Fu-Chen Kuo, Sheng-Wen Su, Chia-Fang Wu, Meng-Chuan Huang, Jentaie Shiea, Bai-Hsiu Chen, Yi-Ling Chen, Ming-Tsang Wu. Relationship of urinary phthalate metabolites with serum thyroid hormones in pregnant women and their newborns: a prospective birth cohort in Taiwan. PloS one. 2015; 10(6):e0123884. doi: 10.1371/journal.pone.0123884. [PMID: 26042594]
Kelly K Ferguson, Karen E Peterson, Joyce M Lee, Adriana Mercado-García, Clara Blank-Goldenberg, Martha M Téllez-Rojo, John D Meeker. Prenatal and peripubertal phthalates and bisphenol A in relation to sex hormones and puberty in boys. Reproductive toxicology (Elmsford, N.Y.). 2014 Aug; 47(?):70-6. doi: 10.1016/j.reprotox.2014.06.002. [PMID: 24945889]
Ulla Nordström Joensen, Niels Jørgensen, Michael Meldgaard, Hanne Frederiksen, Anna-Maria Andersson, Torkil Menné, Jeanne Duus Johansen, Berit Christina Carlsen, Steen Stender, Pal Bela Szecsi, Niels Erik Skakkebæk, Ewa Rajpert-De Meyts, Jacob P Thyssen. Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men. Environmental health perspectives. 2014 Apr; 122(4):345-50. doi: 10.1289/ehp.1306720. [PMID: 24380925]
Joanna Jurewicz, Michał Radwan, Wojciech Sobala, Danuta Ligocka, Paweł Radwan, Michał Bochenek, Wanda Hawuła, Lucjusz Jakubowski, Wojciech Hanke. Human urinary phthalate metabolites level and main semen parameters, sperm chromatin structure, sperm aneuploidy and reproductive hormones. Reproductive toxicology (Elmsford, N.Y.). 2013 Dec; 42(?):232-41. doi: 10.1016/j.reprotox.2013.10.001. [PMID: 24140385]
Liangpo Liu, Tongwei Xia, Lihua Guo, Lanyu Cao, Benhua Zhao, Jie Zhang, Sijun Dong, Heqing Shen. Expressing urine from a gel disposable diaper for biomonitoring using phthalates as an example. Journal of exposure science & environmental epidemiology. 2012 Nov; 22(6):625-31. doi: 10.1038/jes.2012.51. [PMID: 22643239]
Allan C Just, Robin M Whyatt, Matthew S Perzanowski, Antonia M Calafat, Frederica P Perera, Inge F Goldstein, Qixuan Chen, Andrew G Rundle, Rachel L Miller. Prenatal exposure to butylbenzyl phthalate and early eczema in an urban cohort. Environmental health perspectives. 2012 Oct; 120(10):1475-80. doi: 10.1289/ehp.1104544. [PMID: 22732598]
Mei Chen, Lin Tao, Erin M Collins, Christine Austin, Chensheng Lu. Simultaneous determination of multiple phthalate metabolites and bisphenol-A in human urine by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Sep; 904(?):73-80. doi: 10.1016/j.jchromb.2012.07.022. [PMID: 22884473]
Tamarra James-Todd, Richard Stahlhut, John D Meeker, Sheena-Gail Powell, Russ Hauser, Tianyi Huang, Janet Rich-Edwards. Urinary phthalate metabolite concentrations and diabetes among women in the National Health and Nutrition Examination Survey (NHANES) 2001-2008. Environmental health perspectives. 2012 Sep; 120(9):1307-13. doi: 10.1289/ehp.1104717. [PMID: 22796563]
Jessie P Buckley, Rachel T Palmieri, Jeanine M Matuszewski, Amy H Herring, Donna D Baird, Katherine E Hartmann, Jane A Hoppin. Consumer product exposures associated with urinary phthalate levels in pregnant women. Journal of exposure science & environmental epidemiology. 2012 Sep; 22(5):468-75. doi: 10.1038/jes.2012.33. [PMID: 22760436]
Giovanna Tranfo, Lidia Caporossi, Enrico Paci, Cesare Aragona, Daniela Romanzi, Caterina De Carolis, Mariangela De Rosa, Silvia Capanna, Bruno Papaleo, Alessandra Pera. Urinary phthalate monoesters concentration in couples with infertility problems. Toxicology letters. 2012 Aug; 213(1):15-20. doi: 10.1016/j.toxlet.2011.11.033. [PMID: 22197707]
H Frederiksen, K Sørensen, A Mouritsen, L Aksglaede, C P Hagen, J H Petersen, N E Skakkebaek, A-M Andersson, A Juul. High urinary phthalate concentration associated with delayed pubarche in girls. International journal of andrology. 2012 Jun; 35(3):216-26. doi: 10.1111/j.1365-2605.2012.01260.x. [PMID: 22428786]
Joe M Braun, Kristen W Smith, Paige L Williams, Antonia M Calafat, Katharine Berry, Shelley Ehrlich, Russ Hauser. Variability of urinary phthalate metabolite and bisphenol A concentrations before and during pregnancy. Environmental health perspectives. 2012 May; 120(5):739-45. doi: 10.1289/ehp.1104139. [PMID: 22262702]
Roni W Kobrosly, Lauren E Parlett, Richard W Stahlhut, Emily S Barrett, Shanna H Swan. Socioeconomic factors and phthalate metabolite concentrations among United States women of reproductive age. Environmental research. 2012 May; 115(?):11-7. doi: 10.1016/j.envres.2012.03.008. [PMID: 22472009]
Claire Philippat, Marion Mortamais, Cécile Chevrier, Claire Petit, Antonia M Calafat, Xiaoyun Ye, Manori J Silva, Christian Brambilla, Isabelle Pin, Marie-Aline Charles, Sylvaine Cordier, Rémy Slama. Exposure to phthalates and phenols during pregnancy and offspring size at birth. Environmental health perspectives. 2012 Mar; 120(3):464-70. doi: 10.1289/ehp.1103634. [PMID: 21900077]
Gunnar Toft, Bo A G Jönsson, Christian H Lindh, Tina Kold Jensen, Niels H Hjollund, Anne Vested, Jens Peter Bonde. Association between pregnancy loss and urinary phthalate levels around the time of conception. Environmental health perspectives. 2012 Mar; 120(3):458-63. doi: 10.1289/ehp.1103552. [PMID: 22113848]
Robin M Whyatt, Xinhua Liu, Virginia A Rauh, Antonia M Calafat, Allan C Just, Lori Hoepner, Diurka Diaz, James Quinn, Jennifer Adibi, Frederica P Perera, Pam Factor-Litvak. Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of age. Environmental health perspectives. 2012 Feb; 120(2):290-5. doi: 10.1289/ehp.1103705. [PMID: 21893441]
Kelly K Ferguson, Rita Loch-Caruso, John D Meeker. Exploration of oxidative stress and inflammatory markers in relation to urinary phthalate metabolites: NHANES 1999-2006. Environmental science & technology. 2012 Jan; 46(1):477-85. doi: 10.1021/es202340b. [PMID: 22085025]
Lena Olsén, Erik Lampa, Detlef A Birkholz, Lars Lind, P Monica Lind. Circulating levels of bisphenol A (BPA) and phthalates in an elderly population in Sweden, based on the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS). Ecotoxicology and environmental safety. 2012 Jan; 75(1):242-8. doi: 10.1016/j.ecoenv.2011.09.004. [PMID: 21955883]
Thomas Göen, Lorenz Dobler, Jan Koschorreck, Johannes Müller, Gerhard Andreas Wiesmüller, Hans Drexler, Marike Kolossa-Gehring. Trends of the internal phthalate exposure of young adults in Germany--follow-up of a retrospective human biomonitoring study. International journal of hygiene and environmental health. 2011 Dec; 215(1):36-45. doi: 10.1016/j.ijheh.2011.07.011. [PMID: 21889907]
Katherine Svensson, Raúl U Hernández-Ramírez, Ana Burguete-García, Mariano E Cebrián, Antonia M Calafat, Larry L Needham, Luz Claudio, Lizbeth López-Carrillo. Phthalate exposure associated with self-reported diabetes among Mexican women. Environmental research. 2011 Aug; 111(6):792-6. doi: 10.1016/j.envres.2011.05.015. [PMID: 21696718]
Sheela Sathyanarayana, Joe M Braun, Kimberly Yolton, Stacey Liddy, Bruce P Lanphear. Case report: high prenatal bisphenol a exposure and infant neonatal neurobehavior. Environmental health perspectives. 2011 Aug; 119(8):1170-5. doi: 10.1289/ehp.1003064. [PMID: 21524981]
Hanne Frederiksen, Lise Aksglaede, Kaspar Sorensen, Niels E Skakkebaek, Anders Juul, Anna-Maria Andersson. Urinary excretion of phthalate metabolites in 129 healthy Danish children and adolescents: estimation of daily phthalate intake. Environmental research. 2011 Jul; 111(5):656-63. doi: 10.1016/j.envres.2011.03.005. [PMID: 21429484]
Kelly K Ferguson, Rita Loch-Caruso, John D Meeker. Urinary phthalate metabolites in relation to biomarkers of inflammation and oxidative stress: NHANES 1999-2006. Environmental research. 2011 Jul; 111(5):718-26. doi: 10.1016/j.envres.2011.02.002. [PMID: 21349512]
Ruthann A Rudel, Janet M Gray, Connie L Engel, Teresa W Rawsthorne, Robin E Dodson, Janet M Ackerman, Jeanne Rizzo, Janet L Nudelman, Julia Green Brody. Food packaging and bisphenol A and bis(2-ethyhexyl) phthalate exposure: findings from a dietary intervention. Environmental health perspectives. 2011 Jul; 119(7):914-20. doi: 10.1289/ehp.1003170. [PMID: 21450549]
Michelle Romero-Franco, Raúl U Hernández-Ramírez, Antonia M Calafat, Mariano E Cebrián, Larry L Needham, Susan Teitelbaum, Mary S Wolff, Lizbeth López-Carrillo. Personal care product use and urinary levels of phthalate metabolites in Mexican women. Environment international. 2011 Jul; 37(5):867-71. doi: 10.1016/j.envint.2011.02.014. [PMID: 21429583]
Justin A Colacino, Amr S Soliman, Antonia M Calafat, Muna S Nahar, Adrienne Van Zomeren-Dohm, Ahmed Hablas, Ibrahim A Seifeldin, Laura S Rozek, Dana C Dolinoy. Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: a pilot exposure assessment study. Environmental health : a global access science source. 2011 May; 10(?):40. doi: 10.1186/1476-069x-10-40. [PMID: 21575223]
Didik Priyandoko, Tetsuro Ishii, Sunil C Kaul, Renu Wadhwa. Ashwagandha leaf derived withanone protects normal human cells against the toxicity of methoxyacetic acid, a major industrial metabolite. PloS one. 2011 May; 6(5):e19552. doi: 10.1371/journal.pone.0019552. [PMID: 21573189]
Malene Boas, Hanne Frederiksen, Ulla Feldt-Rasmussen, Niels E Skakkebæk, Laszlo Hegedüs, Linda Hilsted, Anders Juul, Katharina M Main. Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth. Environmental health perspectives. 2010 Oct; 118(10):1458-64. doi: 10.1289/ehp.0901331. [PMID: 20621847]
Hanne Frederiksen, Niels Jørgensen, Anna-Maria Andersson. Correlations between phthalate metabolites in urine, serum, and seminal plasma from young Danish men determined by isotope dilution liquid chromatography tandem mass spectrometry. Journal of analytical toxicology. 2010 Sep; 34(7):400-10. doi: 10.1093/jat/34.7.400. [PMID: 20822678]
Fumio Kondo, Yoshitomo Ikai, Rumiko Hayashi, Masanao Okumura, Satoshi Takatori, Hiroyuki Nakazawa, Shun-ichiro Izumi, Tsunehisa Makino. Determination of five phthalate monoesters in human urine using gas chromatography-mass spectrometry. Bulletin of environmental contamination and toxicology. 2010 Jul; 85(1):92-6. doi: 10.1007/s00128-010-0051-8. [PMID: 20574658]
Justin A Colacino, T Robert Harris, Arnold Schecter. Dietary intake is associated with phthalate body burden in a nationally representative sample. Environmental health perspectives. 2010 Jul; 118(7):998-1003. doi: 10.1289/ehp.0901712. [PMID: 20392686]
Mary S Wolff, Susan L Teitelbaum, Susan M Pinney, Gayle Windham, Laura Liao, Frank Biro, Lawrence H Kushi, Chris Erdmann, Robert A Hiatt, Michael E Rybak, Antonia M Calafat. Investigation of relationships between urinary biomarkers of phytoestrogens, phthalates, and phenols and pubertal stages in girls. Environmental health perspectives. 2010 Jul; 118(7):1039-46. doi: 10.1289/ehp.0901690. [PMID: 20308033]
Jennifer Weuve, Russ Hauser, Antonia M Calafat, Stacey A Missmer, Lauren A Wise. Association of exposure to phthalates with endometriosis and uterine leiomyomata: findings from NHANES, 1999-2004. Environmental health perspectives. 2010 Jun; 118(6):825-32. doi: 10.1289/ehp.0901543. [PMID: 20185384]
Lizbeth López-Carrillo, Raúl U Hernández-Ramírez, Antonia M Calafat, Luisa Torres-Sánchez, Marcia Galván-Portillo, Larry L Needham, Rubén Ruiz-Ramos, Mariano E Cebrián. Exposure to phthalates and breast cancer risk in northern Mexico. Environmental health perspectives. 2010 Apr; 118(4):539-44. doi: 10.1289/ehp.0901091. [PMID: 20368132]
E E Hatch, J W Nelson, R W Stahlhut, T F Webster. Association of endocrine disruptors and obesity: perspectives from epidemiological studies. International journal of andrology. 2010 Apr; 33(2):324-32. doi: 10.1111/j.1365-2605.2009.01035.x. [PMID: 20113374]
Jennifer J Adibi, Robin M Whyatt, Russ Hauser, Hari K Bhat, Barbara J Davis, Antonia M Calafat, Lori A Hoepner, Frederica P Perera, Deliang Tang, Paige L Williams. Transcriptional biomarkers of steroidogenesis and trophoblast differentiation in the placenta in relation to prenatal phthalate exposure. Environmental health perspectives. 2010 Feb; 118(2):291-6. doi: 10.1289/ehp.0900788. [PMID: 20123604]
Jennifer David Peck, Anne M Sweeney, Elane Symanski, Joseph Gardiner, Manori J Silva, Antonia M Calafat, Susan L Schantz. Intra- and inter-individual variability of urinary phthalate metabolite concentrations in Hmong women of reproductive age. Journal of exposure science & environmental epidemiology. 2010 Jan; 20(1):90-100. doi: 10.1038/jes.2009.4. [PMID: 19223940]
Hiroaki Itoh, Motoki Iwasaki, Tomoyuki Hanaoka, Hiroshi Sasaki, Tadao Tanaka, Shoichiro Tsugane. Urinary phthalate monoesters and endometriosis in infertile Japanese women. The Science of the total environment. 2009 Dec; 408(1):37-42. doi: 10.1016/j.scitotenv.2009.09.012. [PMID: 19811803]
John D Meeker, Howard Hu, David E Cantonwine, Hector Lamadrid-Figueroa, Antonia M Calafat, Adrienne S Ettinger, Mauricio Hernandez-Avila, Rita Loch-Caruso, Martha María Téllez-Rojo. Urinary phthalate metabolites in relation to preterm birth in Mexico city. Environmental health perspectives. 2009 Oct; 117(10):1587-92. doi: 10.1289/ehp.0800522. [PMID: 20019910]
Antonia M Calafat, Jennifer Weuve, Xiaoyun Ye, Lily T Jia, Howard Hu, Steven Ringer, Ken Huttner, Russ Hauser. Exposure to bisphenol A and other phenols in neonatal intensive care unit premature infants. Environmental health perspectives. 2009 Apr; 117(4):639-44. doi: 10.1289/ehp.0800265. [PMID: 19440505]
Tamar Berman, Drorit Hochner-Celnikier, Antonia M Calafat, Larry L Needham, Yona Amitai, Uri Wormser, Elihu Richter. Phthalate exposure among pregnant women in Jerusalem, Israel: results of a pilot study. Environment international. 2009 Feb; 35(2):353-7. doi: 10.1016/j.envint.2008.08.010. [PMID: 18824263]
Sonia Hernández-Díaz, Allen A Mitchell, Katherine E Kelley, Antonia M Calafat, Russ Hauser. Medications as a potential source of exposure to phthalates in the U.S. population. Environmental health perspectives. 2009 Feb; 117(2):185-9. doi: 10.1289/ehp.11766. [PMID: 19270786]
Erin P Hines, Antonia M Calafat, Manori J Silva, Pauline Mendola, Suzanne E Fenton. Concentrations of phthalate metabolites in milk, urine, saliva, and Serum of lactating North Carolina women. Environmental health perspectives. 2009 Jan; 117(1):86-92. doi: 10.1289/ehp.11610. [PMID: 19165392]
S Sathyanarayana, A M Calafat, F Liu, S H Swan. Maternal and infant urinary phthalate metabolite concentrations: are they related?. Environmental research. 2008 Nov; 108(3):413-8. doi: 10.1016/j.envres.2008.07.002. [PMID: 18715556]
Mary S Wolff, Stephanie M Engel, Gertrud S Berkowitz, Xiaoyun Ye, Manori J Silva, Chenbo Zhu, James Wetmur, Antonia M Calafat. Prenatal phenol and phthalate exposures and birth outcomes. Environmental health perspectives. 2008 Aug; 116(8):1092-7. doi: 10.1289/ehp.11007. [PMID: 18709157]
Elizabeth E Hatch, Jessica W Nelson, M Mustafa Qureshi, Janice Weinberg, Lynn L Moore, Martha Singer, Thomas F Webster. Association of urinary phthalate metabolite concentrations with body mass index and waist circumference: a cross-sectional study of NHANES data, 1999-2002. Environmental health : a global access science source. 2008 Jun; 7(?):27. doi: 10.1186/1476-069x-7-27. [PMID: 18522739]
Jennifer J Adibi, Robin M Whyatt, Paige L Williams, Antonia M Calafat, David Camann, Robert Herrick, Heather Nelson, Hari K Bhat, Frederica P Perera, Manori J Silva, Russ Hauser. Characterization of phthalate exposure among pregnant women assessed by repeat air and urine samples. Environmental health perspectives. 2008 Apr; 116(4):467-73. doi: 10.1289/ehp.10749. [PMID: 18414628]
Johan Högberg, Annika Hanberg, Marika Berglund, Staffan Skerfving, Mikael Remberger, Antonia M Calafat, Agneta Falk Filipsson, Bo Jansson, Niklas Johansson, Malin Appelgren, Helen Håkansson. Phthalate diesters and their metabolites in human breast milk, blood or serum, and urine as biomarkers of exposure in vulnerable populations. Environmental health perspectives. 2008 Mar; 116(3):334-9. doi: 10.1289/ehp.10788. [PMID: 18335100]
John D Meeker, Antonia M Calafat, Russ Hauser. Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men. Environmental health perspectives. 2007 Jul; 115(7):1029-34. doi: 10.1289/ehp.9852. [PMID: 17637918]
Richard W Stahlhut, Edwin van Wijngaarden, Timothy D Dye, Stephen Cook, Shanna H Swan. Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males. Environmental health perspectives. 2007 Jun; 115(6):876-82. doi: 10.1289/ehp.9882. [PMID: 17589594]
Wen-Lan Li, Yu-Bin Ji, Da-Lei Zhang, Yu-Qi Fan. [Identification of metabolites of environmental hormone butylbenzyl phthalate in mice urine by liquid chromatography/ion trap mass spectrometry]. Huan jing ke xue= Huanjing kexue. 2007 Mar; 28(3):627-32. doi: . [PMID: 17633646]
Hermann Fromme, Gabriele Bolte, Holger M Koch, Jürgen Angerer, Sigrun Boehmer, Hans Drexler, Richard Mayer, Bernhard Liebl. Occurrence and daily variation of phthalate metabolites in the urine of an adult population. International journal of hygiene and environmental health. 2007 Jan; 210(1):21-33. doi: 10.1016/j.ijheh.2006.09.005. [PMID: 17182278]
Antonia M Calafat, Richard H McKee. Integrating biomonitoring exposure data into the risk assessment process: phthalates [diethyl phthalate and di(2-ethylhexyl) phthalate] as a case study. Environmental health perspectives. 2006 Nov; 114(11):1783-9. doi: 10.1289/ehp.9059. [PMID: 17107868]
Jennifer Weuve, Brisa N Sánchez, Antonia M Calafat, Ted Schettler, Ronald A Green, Howard Hu, Russ Hauser. Exposure to phthalates in neonatal intensive care unit infants: urinary concentrations of monoesters and oxidative metabolites. Environmental health perspectives. 2006 Sep; 114(9):1424-31. doi: 10.1289/ehp.8926. [PMID: 16966100]
Manori J Silva, John A Reidy, Ella Samandar, Arnetra R Herbert, Larry L Needham, Antonia M Calafat. Detection of phthalate metabolites in human saliva. Archives of toxicology. 2005 Nov; 79(11):647-52. doi: 10.1007/s00204-005-0674-4. [PMID: 15995852]
Susan M Duty, Robin M Ackerman, Antonia M Calafat, Russ Hauser. Personal care product use predicts urinary concentrations of some phthalate monoesters. Environmental health perspectives. 2005 Nov; 113(11):1530-5. doi: 10.1289/ehp.8083. [PMID: 16263507]
Ronald Green, Russ Hauser, Antonia M Calafat, Jennifer Weuve, Ted Schettler, Steven Ringer, Kenneth Huttner, Howard Hu. Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants. Environmental health perspectives. 2005 Sep; 113(9):1222-5. doi: 10.1289/ehp.7932. [PMID: 16140631]
Shanna H Swan, Katharina M Main, Fan Liu, Sara L Stewart, Robin L Kruse, Antonia M Calafat, Catherine S Mao, J Bruce Redmon, Christine L Ternand, Shannon Sullivan, J Lynn Teague. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environmental health perspectives. 2005 Aug; 113(8):1056-61. doi: 10.1289/ehp.8100. [PMID: 16079079]
Russ Hauser, Paige Williams, Larisa Altshul, Antonia M Calafat. Evidence of interaction between polychlorinated biphenyls and phthalates in relation to human sperm motility. Environmental health perspectives. 2005 Apr; 113(4):425-30. doi: 10.1289/ehp.7305. [PMID: 15811833]
Susan M Duty, Antonia M Calafat, Manori J Silva, Louise Ryan, Russ Hauser. Phthalate exposure and reproductive hormones in adult men. Human reproduction (Oxford, England). 2005 Mar; 20(3):604-10. doi: 10.1093/humrep/deh656. [PMID: 15591081]
Russ Hauser, John D Meeker, Sohee Park, Manori J Silva, Antonia M Calafat. Temporal variability of urinary phthalate metabolite levels in men of reproductive age. Environmental health perspectives. 2004 Dec; 112(17):1734-40. doi: 10.1289/ehp.7212. [PMID: 15579421]
Russ Hauser, Susan Duty, Linda Godfrey-Bailey, Antonia M Calafat. Medications as a source of human exposure to phthalates. Environmental health perspectives. 2004 May; 112(6):751-3. doi: 10.1289/ehp.6804. [PMID: 15121520]
Anders Holm, Kasper Solbu, Paal Molander, Elsa Lundanes, Tyge Greibrokk. Sensitive biomonitoring of phthalate metabolites in human urine using packed capillary column switching liquid chromatography coupled to electrospray ionization ion-trap mass spectrometry. Analytical and bioanalytical chemistry. 2004 Apr; 378(7):1762-8. doi: 10.1007/s00216-003-2488-7. [PMID: 14758462]
Manori J Silva, Dana B Barr, John A Reidy, Nicole A Malek, Carolyn C Hodge, Samuel P Caudill, John W Brock, Larry L Needham, Antonia M Calafat. Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000. Environmental health perspectives. 2004 Mar; 112(3):331-8. doi: 10.1289/ehp.6723. [PMID: 14998749]
Jennifer J Adibi, Frederica P Perera, Wieslaw Jedrychowski, David E Camann, Dana Barr, Ryszard Jacek, Robin M Whyatt. Prenatal exposures to phthalates among women in New York City and Krakow, Poland. Environmental health perspectives. 2003 Nov; 111(14):1719-22. doi: 10.1289/ehp.6235. [PMID: 14594621]
Manori J Silva, Nicole A Malek, Carolyn C Hodge, John A Reidy, Kayoko Kato, Dana B Barr, Larry L Needham, John W Brock. Improved quantitative detection of 11 urinary phthalate metabolites in humans using liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2003 Jun; 789(2):393-404. doi: 10.1016/s1570-0232(03)00164-8. [PMID: 12742130]
Kayoko Kato, Sachiko Shoda, Masakazu Takahashi, Natsuko Doi, Yoshihiro Yoshimura, Hiroyuki Nakazawa. Determination of three phthalate metabolites in human urine using on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2003 May; 788(2):407-11. doi: 10.1016/s1570-0232(03)00041-2. [PMID: 12705982]
Susan M Duty, Manori J Silva, Dana B Barr, John W Brock, Louise Ryan, Zuying Chen, Robert F Herrick, David C Christiani, Russ Hauser. Phthalate exposure and human semen parameters. Epidemiology (Cambridge, Mass.). 2003 May; 14(3):269-77. doi: NULL. [PMID: 12859026]
Jane A Hoppin, John W Brock, Barbara J Davis, Donna D Baird. Reproducibility of urinary phthalate metabolites in first morning urine samples. Environmental health perspectives. 2002 May; 110(5):515-8. doi: 10.1289/ehp.02110515. [PMID: 12003755]
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