Finasteride (BioDeep_00000398395)

   

natural product


代谢物信息卡片


Finasteride

化学式: C23H36N2O2 (372.2776636)
中文名称: 非那甾胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(N[C@]2([C@](C=1)([C@]3([C@@](CC2)([C@]4([C@](CC3)([C@@H](CC4)C(NC(C)(C)C)=O)C)[H])[H])[H])C)[H])=O
InChI: InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1

描述信息

G - Genito urinary system and sex hormones > G04 - Urologicals > G04C - Drugs used in benign prostatic hypertrophy > G04CB - Testosterone-5-alpha reductase inhibitors
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D065088 - Steroid Synthesis Inhibitors
D004791 - Enzyme Inhibitors > D065088 - Steroid Synthesis Inhibitors > D058891 - 5-alpha Reductase Inhibitors
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C242 - Anti-Androgen
D000089162 - Genitourinary Agents > D064804 - Urological Agents
C471 - Enzyme Inhibitor > C2319 - 5 Alpha-Reductase Inhibitor
C1892 - Chemopreventive Agent
D - Dermatologicals
CONFIDENCE standard compound; INTERNAL_ID 541; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9164; ORIGINAL_PRECURSOR_SCAN_NO 9159
CONFIDENCE standard compound; INTERNAL_ID 541; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9203; ORIGINAL_PRECURSOR_SCAN_NO 9201
CONFIDENCE standard compound; INTERNAL_ID 541; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9222; ORIGINAL_PRECURSOR_SCAN_NO 9221
CONFIDENCE standard compound; INTERNAL_ID 541; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9254; ORIGINAL_PRECURSOR_SCAN_NO 9252
CONFIDENCE standard compound; INTERNAL_ID 541; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9266; ORIGINAL_PRECURSOR_SCAN_NO 9265
CONFIDENCE standard compound; INTERNAL_ID 541; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9274; ORIGINAL_PRECURSOR_SCAN_NO 9273
CONFIDENCE standard compound; INTERNAL_ID 2702
CONFIDENCE standard compound; INTERNAL_ID 4115

同义名列表

1 个代谢物同义名

Finasteride



数据库引用编号

30 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Wenzuo Luo, Xingui Zhang, Yingying Chu, Tiantian Chen, Huixuan Sun, Jiadong Liu, Guoxing Zhang, Lihong Fan, Haixing Xu, Yue Zhang, Ming Yang. Incorporation of Finasteride-Loaded Microspheres into Personalized Microneedle for Sustained Transdermal Delivery. Langmuir : the ACS journal of surfaces and colloids. 2024 May; 40(20):10551-10560. doi: 10.1021/acs.langmuir.4c00280. [PMID: 38710593]
  • Patrick McQueen, Donald Molina, Ivan Pinos, Samuel Krug, Anna J Taylor, Michael R LaFrano, Maureen A Kane, Jaume Amengual. Finasteride delays atherosclerosis progression in mice and is associated with a reduction in plasma cholesterol in men. Journal of lipid research. 2024 Jan; ?(?):100507. doi: 10.1016/j.jlr.2024.100507. [PMID: 38272355]
  • Iman Nabil, Amira Abulfotooh Eid, Hend A Yassin, Rana Ahmed Abouelrous, Amany A Solaiman. Protective role of hesperidin in finasteride-induced testicular toxicity in adult male Wistar rats: Insights into oxidative stress, apoptosis, and ultrastructure of seminiferous tubules. Reproductive toxicology (Elmsford, N.Y.). 2024 Jan; 124(?):108535. doi: 10.1016/j.reprotox.2024.108535. [PMID: 38216069]
  • Deusdedit Tusubira, Patrick M Aja, Jonasi Munezero, Frank Ssedyabane, Nathim Namale, Josiah E Ifie, Peter C Agu, Clement O Ajayi, Joash Okoboi. Safety profile of colocasia esculenta tuber extracts in benign prostate hyperplasia. BMC complementary medicine and therapies. 2023 Jun; 23(1):187. doi: 10.1186/s12906-023-04018-4. [PMID: 37286957]
  • Basma H Marghani, Mohamed Aboul Ezz, Ahmed I Ateya, Alaa Fehaid, Rasha M Saleh, Shaymaa Rezk. Comparative effects of finasteride and laser-irradiated silver nanoparticles on testicular function and histology in testosterone induced benign prostatic hyperplasia in rats. Life sciences. 2023 May; 324(?):121747. doi: 10.1016/j.lfs.2023.121747. [PMID: 37137466]
  • Biao Liu, Tian Fang, Lei Liang, Wen-Juan Hu, Min Dong, Li Chen, Wei Wu, Shi-Feng Yun. [Rauwolfia extract inhibits the proliferation of prostate cells in rats with benign prostatic hyperplasia]. Zhonghua nan ke xue = National journal of andrology. 2023 Mar; 29(3):195-201. doi: ". [PMID: 38597699]
  • Khaled M Hosny, Waleed Y Rizg, Eman Alfayez, Samar S Elgebaly, Abdulmohsin J Alamoudi, Raed I Felimban, Hossam H Tayeb, Rayan Y Mushtaq, Awaji Y Safhi, Majed Alharbi, Alshaimaa M Almehmady. Preparation and optimization of aloe ferox gel loaded with Finasteride-Oregano oil nanocubosomes for treatment of alopecia. Drug delivery. 2022 Dec; 29(1):284-293. doi: 10.1080/10717544.2022.2026534. [PMID: 35019794]
  • Young-Jin Choi, Meiqi Fan, Nishala Erandi Wedamulla, Yujiao Tang, Sung Mun Bae, Ji-Young Hwang, Eun-Kyung Kim. Inhibitory effects of Centella asiatica (L.) Urban on enlarged prostate through androgen receptor and PI3K/Akt signaling pathways. Food & function. 2022 Oct; 13(19):10235-10247. doi: 10.1039/d2fo00841f. [PMID: 36124918]
  • Chi Liu, Hongwei Zhao, Ying Zhang, Wei Wu. Clinical observation of basic fibroblast growth factor (bFGF) combined with minoxidil in the treatment of male androgenetic alopecia. Journal of cosmetic dermatology. 2022 Sep; 21(9):4053-4059. doi: 10.1111/jocd.14735. [PMID: 35037386]
  • Kate Eleazu, Patrick Maduabuchi Aja, Chinedum Ogbonnaya Eleazu. Cocoyam (Colocasia esculenta) modulates some parameters of testosterone propionate-induced rat model of benign prostatic hyperplasia. Drug and chemical toxicology. 2022 Sep; 45(5):1923-1933. doi: 10.1080/01480545.2021.1892956. [PMID: 33641553]
  • Abdulmohsin J Alamoudi, Sami A Alessi, Waleed Y Rizg, Abdulmajeed M Jali, Awaji Y Safhi, Fahad Y Sabei, Sameer Alshehri, Khaled M Hosny, Ashraf B Abdel-Naim. Cordycepin Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats via Modulation of AMPK and AKT Activation. Pharmaceutics. 2022 Aug; 14(8):. doi: 10.3390/pharmaceutics14081652. [PMID: 36015278]
  • Geum-Lan Hong, Tae-Won Kim, Hui-Ju Lee, Yae-Ji Kim, Kyung-Hyun Kim, Ju-Young Jung. The extract of Celtis choseniana Nakai alleviates testosterone-induced benign prostatic hyperplasia through inhibiting 5α reductase type 2 and the Akt/NF-κB/AR pathway. Chinese journal of natural medicines. 2022 Jul; 20(7):518-526. doi: 10.1016/s1875-5364(22)60178-x. [PMID: 35907650]
  • Hangy Lee, Seung Joo Moon, Yeong Du Yoo, Eun Ju Jeong, Jung-Rae Rho. Voratins A-C: Pyridinium Alkaloids from the Marine Dinoflagellate Effrenium voratum with Inhibitory Effects on Biomarkers for Benign Prostatic Hyperplasia. Journal of natural products. 2022 06; 85(6):1495-1502. doi: 10.1021/acs.jnatprod.1c01190. [PMID: 35671052]
  • Aditya K Gupta, Mesbah Talukder. Topical finasteride for male and female pattern hair loss: Is it a safe and effective alternative?. Journal of cosmetic dermatology. 2022 May; 21(5):1841-1848. doi: 10.1111/jocd.14895. [PMID: 35238144]
  • Greice Klein da Cruz, Maria Isabel Morgan Martins, Flavia Tasmin Techera Antunes, Alessandra Hubner de Souza, Elenir de Fátima Wiilland, Jaqueline Nascimento Picada, Lucimar Filot da Silva Brum. Evaluation of the efficacy and toxicity of oral and topical pumpkin oil on the hair growth of mice. Acta histochemica. 2022 May; 124(4):151894. doi: 10.1016/j.acthis.2022.151894. [PMID: 35447441]
  • D Todeschini, I C Pedro Martinez, M Dutra Duque. Topical finasteride dose evaluation for treatment of androgenetic alopecia using computer simulations. Annales pharmaceutiques francaises. 2022 Mar; 80(2):169-175. doi: 10.1016/j.pharma.2021.08.002. [PMID: 34425076]
  • Basma H Marghani, Alaa Fehaid, Ahmed I Ateya, Mohamed Aboul Ezz, Rasha M Saleh. Photothermal therapeutic potency of plasmonic silver nanoparticles for apoptosis and anti-angiogenesis in testosterone induced benign prostate hyperplasia in rats. Life sciences. 2022 Feb; 291(?):120240. doi: 10.1016/j.lfs.2021.120240. [PMID: 34942164]
  • B M Piraccini, U Blume-Peytavi, F Scarci, J M Jansat, M Falqués, R Otero, M L Tamarit, J Galván, V Tebbs, E Massana. Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial. Journal of the European Academy of Dermatology and Venereology : JEADV. 2022 Feb; 36(2):286-294. doi: 10.1111/jdv.17738. [PMID: 34634163]
  • Aditya K Gupta, Mary A Bamimore, Kelly A Foley. Efficacy of non-surgical treatments for androgenetic alopecia in men and women: a systematic review with network meta-analyses, and an assessment of evidence quality. The Journal of dermatological treatment. 2022 Feb; 33(1):62-72. doi: 10.1080/09546634.2020.1749547. [PMID: 32250713]
  • Cindy H Chau, Cathee Till, Douglas K Price, Phyllis J Goodman, Marian L Neuhouser, Michael N Pollak, Ian M Thompson, William D Figg. Serum markers, obesity and prostate cancer risk: results from the prostate cancer prevention trial. Endocrine-related cancer. 2022 01; 29(2):99-109. doi: 10.1530/erc-21-0107. [PMID: 34889205]
  • Muhammad Sohaib, Shefaat Ullah Shah, Kifayat Ullah Shah, Kifayat Ullah Shah, Nauman Rahim Khan, Malik Muhammad Irfan, Zahid Rasul Niazi, Abdulsalam A Alqahtani, Ali Alasiri, Ismail A Walbi, Sajid Mahmood. Physicochemical Characterization of Chitosan-Decorated Finasteride Solid Lipid Nanoparticles for Skin Drug Delivery. BioMed research international. 2022; 2022(?):7792180. doi: 10.1155/2022/7792180. [PMID: 35971450]
  • Christina M Ring, Robert Finney, Marc Avram. Lasers, lights, and compounds for hair loss in aesthetics. Clinics in dermatology. 2022 Jan; 40(1):64-75. doi: 10.1016/j.clindermatol.2021.08.013. [PMID: 35190067]
  • Ehsan Shabani, Heibatullah Kalantari, Mojtaba Kalantar, Mehdi Goudarzi, Esrafil Mansouri, Hadi Kalantar. Berberine ameliorates testosterone-induced benign prostate hyperplasia in rats. BMC complementary medicine and therapies. 2021 Dec; 21(1):301. doi: 10.1186/s12906-021-03472-2. [PMID: 34930229]
  • Loredana Iannella, Cristiana Colamonici, Davide Curcio, Francesco Botrè, Xavier de la Torre. 5α-reductase inhibitors: Evaluation of their potential confounding effect on GC-C-IRMS doping analysis. Drug testing and analysis. 2021 Nov; 13(11-12):1852-1861. doi: 10.1002/dta.3134. [PMID: 34318592]
  • Ying Peng, Chongsheng Peng, Yang Wu, Chongzhi Sun, Xiaobo Li. Chemical profiles of the active fraction from Prinsepia utilis Royle leaves and its anti-benign prostatic hyperplasia evaluation in animal models. BMC complementary medicine and therapies. 2021 Oct; 21(1):272. doi: 10.1186/s12906-021-03446-4. [PMID: 34715848]
  • Yani Zhao, Yan Zhang, Yao Li, Min Yang, Jiani Yuan, Yu Cao, Lu Xu, Xuexinyu Ma, Sisong Lin, Junming An, Siwang Wang. Yohimbine hydrochloride inhibits benign prostatic hyperplasia by downregulating steroid 5α-reductase type 2. European journal of pharmacology. 2021 Oct; 908(?):174334. doi: 10.1016/j.ejphar.2021.174334. [PMID: 34265299]
  • Skyler Howell, Weitao Song, Alexander Pastuszak, Mohit Khera. Differential Gene Expression in Post-Finasteride Syndrome Patients. The journal of sexual medicine. 2021 09; 18(9):1479-1490. doi: 10.1016/j.jsxm.2021.05.009. [PMID: 34247957]
  • Dong Wook Kang, Choong Ho Ryu, Ju Hee Kim, Go-Wun Choi, Seyeon Kim, Chan Hee Chon, Ju Hee Kim, Hea-Young Cho. Pharmacokinetic-pharmacodynamic modeling approach for dose prediction of the optimal long-acting injectable formulation of finasteride. International journal of pharmaceutics. 2021 May; 601(?):120527. doi: 10.1016/j.ijpharm.2021.120527. [PMID: 33781881]
  • Arpar Ngampanya, Udomsak Udomnilobol, Pakawadee Sermsappasuk, Natapol Pornputtapong, Boonsri Ongpipattanakul, Nikunjkumar Patel, Suree Jianmongkol, Thomayant Prueksaritanont. Development and Qualification of a Physiologically Based Pharmacokinetic Model of Finasteride and Minoxidil Following Scalp Application. Journal of pharmaceutical sciences. 2021 05; 110(5):2301-2310. doi: 10.1016/j.xphs.2021.02.016. [PMID: 33609522]
  • D S Shah, D K Jha, P D Amin. Development, validation, and application of an RP-HPLC method for concurrent quantification of Minoxidil and Finasteride in a topical solution for hair regrowth. Annales pharmaceutiques francaises. 2021 Mar; 79(2):194-206. doi: 10.1016/j.pharma.2020.10.003. [PMID: 33091398]
  • Bo-Ram Jin, Jae-Yun Ju, Agung Nugroho, Minho Lee, Hyo-Jin An. Carica papaya leaf extract inhibits prostatitis-associated prostatic hyperplasia via the TRAF6/TAK1/MEK/NF-κB pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 Mar; 135(?):111197. doi: 10.1016/j.biopha.2020.111197. [PMID: 33433362]
  • Paulina Kur, Agnieszka Kolasa-Wołosiuk, Marta Grabowska, Andrzej Kram, Maciej Tarnowski, Irena Baranowska-Bosiacka, Sylwia Rzeszotek, Małgorzata Piasecka, Barbara Wiszniewska. The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycaemia, Elevated Hepatic Glycogen Storage and Altered GLUT2, IR, and AR Expression in the Liver. International journal of molecular sciences. 2021 Jan; 22(3):. doi: 10.3390/ijms22031242. [PMID: 33513940]
  • Mohammad Ali Farshid, Mehdi Fazeli, Tahoora Shomali, Saeed Nazifi, Fatemeh Namazi. Protective effect of black mulberry (Morus nigra L.) fruit hydroalcoholic extract against testosterone-induced benign prostatic hyperplasia in rats. Revista internacional de andrologia. 2021 Jan; 19(1):53-61. doi: 10.1016/j.androl.2019.09.003. [PMID: 31899187]
  • Marcello Henrique Araújo da Silva, João Henrique Duque Estrada, Bianca Martins Gregório, Francisco José Barcellos Sampaio, Diogo Benchimol de Souza. Does treatment with dutasteride or finasteride has impact on renal morphology? Experimental study. Acta cirurgica brasileira. 2021; 36(7):e360703. doi: 10.1590/acb360703. [PMID: 34550196]
  • A Goren, C G Wambier, S Herrera, J McCoy, S Vaño-Galván, F Gioia, B Comeche, R Ron, S Serrano-Villar, P M Ramos, F A Cadegiani, M Kovacevic, A Tosti, J Shapiro, R Sinclair. Anti-androgens may protect against severe COVID-19 outcomes: results from a prospective cohort study of 77 hospitalized men. Journal of the European Academy of Dermatology and Venereology : JEADV. 2021 Jan; 35(1):e13-e15. doi: 10.1111/jdv.16953. [PMID: 32977363]
  • Xiaoning Chen, Hui Feng, Attalla F El-Kott, Eman M Abd-Ella. Origanum vulgare L. leaves extract alleviates testis and sperm damages induced by finasteride: Biochemical, Immunohistological and apoptosis genes based evidences. Andrologia. 2020 Dec; 52(11):e13823. doi: 10.1111/and.13823. [PMID: 32966695]
  • Eman M Elbaz, Hebat Allah A Amin, Ahmed S Kamel, Sherehan M Ibrahim, Hebatullah S Helmy. Immunomodulatory effect of diallyl sulfide on experimentally-induced benign prostate hyperplasia via the suppression of CD4+T/IL-17 and TGF-β1/ERK pathways. Inflammopharmacology. 2020 Oct; 28(5):1407-1420. doi: 10.1007/s10787-020-00743-1. [PMID: 32785828]
  • Mahmoud Makki, Abdel-Khalek Hassan Younes, Islam Salah. Evaluation of the effect of autologous platelet-rich plasma on androgenic alopecia. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. 2020 Jul; 22(4-5):190-194. doi: 10.1080/14764172.2020.1827150. [PMID: 33012215]
  • Jan Adamowicz, Kajetan Juszczak, Tomasz Drewa. May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications?. Medical hypotheses. 2020 Jul; 140(?):109751. doi: 10.1016/j.mehy.2020.109751. [PMID: 32344304]
  • Juliana S Maldarine, Bruno D A Sanches, Vitória A Santos, Ágata S Cabral, Maria L D Lima, Carolina M Bedolo, Marília F Calmon, Paula Rahal, Rejane M Góes, Patricia S L Vilamaior, Sebastião R Taboga. Postnatal exposure to finasteride causes different effects on the prostate of male and female gerbils. Cell biology international. 2020 Jun; 44(6):1341-1352. doi: 10.1002/cbin.11328. [PMID: 32100915]
  • Kathleen Torkko, Cathee Till, Catherine M Tangen, Phyllis J Goodman, Xiaoling Song, Jeannette M Schenk, M Scott Lucia, Ulrike Peters, Adrie van Bokhoven, Ian M Thompson, Marian L Neuhouser. Vitamin D Pathway and Other Related Polymorphisms and Risk of Prostate Cancer: Results from the Prostate Cancer Prevention Trial. Cancer prevention research (Philadelphia, Pa.). 2020 06; 13(6):521-530. doi: 10.1158/1940-6207.capr-19-0413. [PMID: 32102946]
  • S A Nizomov, I V Sorokina, N A Zhukova, S A Borisov, T G Tolstikova, D E Semenov, M A Bakarev. Prostatotropic Action of Glycyrrhizic Acid Disodium Salt in Benign Prostatic Hyperplasia Models. Bulletin of experimental biology and medicine. 2020 May; 169(1):114-118. doi: 10.1007/s10517-020-04836-3. [PMID: 32488776]
  • Pietro Gentile, Simone Garcovich. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil®, Finasteride®, and Adult Stem Cell-Based Therapy. International journal of molecular sciences. 2020 Apr; 21(8):. doi: 10.3390/ijms21082702. [PMID: 32295047]
  • Cinthya Vásquez-Velásquez, Manuel Gasco, Diego Fano-Sizgorich, Gustavo F Gonzales. Inflammatory pathway employed by Red Maca to treat induced benign prostatic hyperplasia in rats. Andrologia. 2020 Apr; 52(3):e13516. doi: 10.1111/and.13516. [PMID: 31989657]
  • Katherine York, Nekma Meah, Bevin Bhoyrul, Rodney Sinclair. A review of the treatment of male pattern hair loss. Expert opinion on pharmacotherapy. 2020 04; 21(5):603-612. doi: 10.1080/14656566.2020.1721463. [PMID: 32066284]
  • Kamran Golchin-Rad, Asghar Mogheiseh, Saeed Nazifi, Mohammad Saeed Ahrari Khafi, Nooshin Derakhshandeh, Mohammad Abbaszadeh-Hasiri. Changes in the Serum Prostatic Biomarkers During the Treatment of Benign Prostatic Hyperplasia with a 5alpha-reductase Inhibitor: Finasteride. Topics in companion animal medicine. 2020 Mar; 38(?):100405. doi: 10.1016/j.tcam.2020.100405. [PMID: 32115076]
  • Gadah Albasher, May Bin-Jumah, Saleh Alfarraj, Fatimah Al-Otibi, Nouf K Al-Sultan, Saud Alarifi, Saad Alkahtani, Nahed S Alharthi, Wedad S Al-Qahtani. Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women. Bioscience reports. 2020 02; 40(2):. doi: 10.1042/bsr20191434. [PMID: 31967291]
  • Gian Maria Busetto, Francesco Del Giudice, Daniele D'Agostino, Daniele Romagnoli, Andrea Minervini, Bernardo Rocco, Alessandro Antonelli, Antonio Celia, Riccardo Schiavina, Luca Cindolo, Benjamin I Chung, Jae Heon Kim, Martina Maggi, Alessandro Sciarra, Ettore De Berardinis, Angelo Porreca. Efficacy and safety of Finasteride (5 alpha-reductase inhibitor) monotherapy in patients with benign prostatic hyperplasia: A critical review of the literature. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. 2020 Jan; 91(4):205-210. doi: 10.4081/aiua.2019.4.205. [PMID: 31937082]
  • Junfeng Liu, Lingyun Lai, Jiajia Lin, Jiajia Zheng, Xiaoli Nie, Xiaoye Zhu, Jun Xue, Te Liu. Ranitidine and finasteride inhibit the synthesis and release of trimethylamine N-oxide and mitigates its cardiovascular and renal damage through modulating gut microbiota. International journal of biological sciences. 2020; 16(5):790-802. doi: 10.7150/ijbs.40934. [PMID: 32071549]
  • Bong Kyun Park, Chang Won Kim, Jeong Eun Kwon, Manorma Negi, Yong Tae Koo, Sang Hun Lee, Dong Hyun Baek, Yoo Hun Noh, Se Chan Kang. Effects of Lespedeza Cuneata aqueous extract on testosterone-induced prostatic hyperplasia. Pharmaceutical biology. 2019 Dec; 57(1):90-98. doi: 10.1080/13880209.2018.1564929. [PMID: 30724641]
  • Kanyarat Sueksakit, Visith Thongboonkerd. Protective effects of finasteride against testosterone-induced calcium oxalate crystallization and crystal-cell adhesion. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2019 10; 24(7):973-983. doi: 10.1007/s00775-019-01692-z. [PMID: 31342142]
  • Tatiele Katzer, Ademir Leite Junior, Ruy Beck, Cristiane da Silva. Physiopathology and current treatments of androgenetic alopecia: Going beyond androgens and anti-androgens. Dermatologic therapy. 2019 09; 32(5):e13059. doi: 10.1111/dth.13059. [PMID: 31400254]
  • A A Alkahtane, G Albasher, N K Al-Sultan, W S Alqahtani, S Alarifi, R S Almeer, J Alghamdi, D Ali, A Alahmari, S Alkahtani. Long-term treatment with finasteride induces apoptosis and pathological changes in female mice. Human & experimental toxicology. 2019 Jul; 38(7):762-774. doi: 10.1177/0960327119842195. [PMID: 30943778]
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