Ac-Gly-OH (BioDeep_00000398342)

Main id: BioDeep_00000017881

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


N-ACETYLGLYCINE

化学式: C4H7NO3 (117.0426)
中文名称: N-乙酰甘氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)NCC(=O)O
InChI: InChI=1S/C4H7NO3/c1-3(6)5-2-4(7)8/h2H2,1H3,(H,5,6)(H,7,8)

描述信息

An N-acylglycine where the acyl group is specified as acetyl.
Acquisition and generation of the data is financially supported in part by CREST/JST.
N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics.

同义名列表

5 个代谢物同义名

N-ACETYLGLYCINE; Ac-Gly-OH; Aceturic acid; Acetamidoacetic acid; N-Acetylglycine



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Kazunari Yoneda, Rina Nagano, Takuya Mikami, Haruhiko Sakuraba, Kenji Fukui, Tomohiro Araki, Toshihisa Ohshima. Catalytic properties and crystal structure of UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase from Phytophthora infestans. Enzyme and microbial technology. 2020 Oct; 140(?):109627. doi: 10.1016/j.enzmictec.2020.109627. [PMID: 32912687]
  • Belinda S Lennerz, Scott B Vafai, Nigel F Delaney, Clary B Clish, Amy A Deik, Kerry A Pierce, David S Ludwig, Vamsi K Mootha. Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans. Molecular genetics and metabolism. 2015 Jan; 114(1):73-9. doi: 10.1016/j.ymgme.2014.11.010. [PMID: 25497115]
  • Avalyn Stanislaus, Kevin Guo, Liang Li. Development of an isotope labeling ultra-high performance liquid chromatography mass spectrometric method for quantification of acylglycines in human urine. Analytica chimica acta. 2012 Oct; 750(?):161-72. doi: 10.1016/j.aca.2012.05.006. [PMID: 23062437]
  • Soumen K Manna, Andrew D Patterson, Qian Yang, Kristopher W Krausz, Jeffrey R Idle, Albert J Fornace, Frank J Gonzalez. UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model. Journal of proteome research. 2011 Sep; 10(9):4120-33. doi: 10.1021/pr200310s. [PMID: 21749142]
  • Nikolaos Psychogios, David D Hau, Jun Peng, An Chi Guo, Rupasri Mandal, Souhaila Bouatra, Igor Sinelnikov, Ramanarayan Krishnamurthy, Roman Eisner, Bijaya Gautam, Nelson Young, Jianguo Xia, Craig Knox, Edison Dong, Paul Huang, Zsuzsanna Hollander, Theresa L Pedersen, Steven R Smith, Fiona Bamforth, Russ Greiner, Bruce McManus, John W Newman, Theodore Goodfriend, David S Wishart. The human serum metabolome. PloS one. 2011 Feb; 6(2):e16957. doi: 10.1371/journal.pone.0016957. [PMID: 21359215]
  • Kirsten Gillingwater, Carlos Gutierrez, Arlene Bridges, Huali Wu, Stijn Deborggraeve, Rosine Ali Ekangu, Arvind Kumar, Mohamed Ismail, David Boykin, Reto Brun. Efficacy study of novel diamidine compounds in a Trypanosoma evansi goat model. PloS one. 2011; 6(6):e20836. doi: 10.1371/journal.pone.0020836. [PMID: 21698106]
  • Blair U Bradford, Thomas M O'Connell, Jun Han, Oksana Kosyk, Svitlana Shymonyak, Pamela K Ross, Jason Winnike, Hiroshi Kono, Ivan Rusyn. Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease. Toxicology and applied pharmacology. 2008 Oct; 232(2):236-43. doi: 10.1016/j.taap.2008.06.022. [PMID: 18674555]
  • L M Makarova, V E Pogorelyĭ. [Experimental evaluation of the effect of glycine and its phosphorylated derivative on ischemic brain injury]. Eksperimental'naia i klinicheskaia farmakologiia. 2006 Nov; 69(6):24-6. doi: ". [PMID: 17209459]
  • Orit Bartov, Rukhsana Sultana, D Allan Butterfield, Daphne Atlas. Low molecular weight thiol amides attenuate MAPK activity and protect primary neurons from Abeta(1-42) toxicity. Brain research. 2006 Jan; 1069(1):198-206. doi: 10.1016/j.brainres.2005.10.079. [PMID: 16386719]
  • Wycliff M Karanja, Raymond E Mdachi, Grace A Murilla. A competitive enzyme-linked immunosorbent assay for diminazene. Acta tropica. 2002 Nov; 84(2):75-81. doi: 10.1016/s0001-706x(02)00184-5. [PMID: 12429424]
  • Magnus Stödeman, Frederick P Schwarz. Importance of product inhibition in the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry. Analytical biochemistry. 2002 Sep; 308(2):285-93. doi: 10.1016/s0003-2697(02)00339-1. [PMID: 12419341]
  • V V Men'shikov, F B Berezin, T D Bol'shakova, Zh Zh Bass, A A Tkachev. [Various indicators of the adrenal cortex activity in practically healthy persons under conditions of extreme North-East of the USSR]. Laboratornoe delo. 1978; ?(5):287-90. doi: NULL. [PMID: 79014]
  • H Isaacs, J J Heffron, M Badenhorst. 'Picture frame' fibres in a carrier of the trait for malignant hyperpyrexia. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 1975 Nov; 49(46):1923-6. doi: NULL. [PMID: 795]