L-beta-Homoproline (BioDeep_00000398304)

   


代谢物信息卡片


(S)-2-(Pyrrolidin-2-yl)acetic acid

化学式: C6H11NO2 (129.0789746)
中文名称: HL-β-HomoPro-OHHCl
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(NC1)CC(=O)O
InChI: InChI=1S/C6H11NO2/c8-6(9)4-5-2-1-3-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1

描述信息

Acquisition and generation of the data is financially supported in part by CREST/JST.

同义名列表

3 个代谢物同义名

(S)-2-(Pyrrolidin-2-yl)acetic acid; L-beta-Homoproline; (S)-Homoproline



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Tobias Steffan, Thejavathi Renukappa-Gutke, Georg Höfner, Klaus T Wanner. Design, synthesis and SAR studies of GABA uptake inhibitors derived from 2-substituted pyrrolidine-2-yl-acetic acids. Bioorganic & medicinal chemistry. 2015 Mar; 23(6):1284-306. doi: 10.1016/j.bmc.2015.01.035. [PMID: 25698617]
  • Mark R Faust, Georg Höfner, Jörg Pabel, Klaus T Wanner. Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship. European journal of medicinal chemistry. 2010 Jun; 45(6):2453-66. doi: 10.1016/j.ejmech.2010.02.029. [PMID: 20219271]
  • Xueqing Zhao, Cornelia E Hoesl, Georg C Hoefner, Klaus T Wanner. Synthesis and biological evaluation of new GABA-uptake inhibitors derived from proline and from pyrrolidine-2-acetic acid. European journal of medicinal chemistry. 2005 Mar; 40(3):231-47. doi: 10.1016/j.ejmech.2004.11.004. [PMID: 15725493]
  • A Köfalvi, B Sperlágh, T Zelles, E S Vizi. Long-lasting facilitation of 4-amino-n-[2,3-(3)H]butyric acid ([(3)H]GABA) release from rat hippocampal slices by nicotinic receptor activation. The Journal of pharmacology and experimental therapeutics. 2000 Nov; 295(2):453-62. doi: NULL. [PMID: 11046076]
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  • C Thomsen, P O Sørensen, J Egebjerg. 1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter. British journal of pharmacology. 1997 Mar; 120(6):983-5. doi: 10.1038/sj.bjp.0700957. [PMID: 9134205]
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