Nadide (BioDeep_00000398297)
PANOMIX_OTCML-2023 BioNovoGene_Lab2019
代谢物信息卡片
beta-Nicotinamide adenine dinucleotide
化学式: C21H27N7O14P2 (663.1091182000001)
中文名称: β-烟酰胺腺嘌呤二核苷酸(NAD), β-烟酰胺腺嘌呤二核苷酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
InChI: InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
描述信息
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Acquisition and generation of the data is financially supported in part by CREST/JST.
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:44215
- PubChem: 5892
- DrugBank: DB14128
- ChEMBL: CHEMBL1234613
- MeSH: NAD
- CAS: 64417-72-7
- CAS: 53-84-9
- MoNA: PR100218
- medchemexpress: HY-B0445
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-1
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Simeng He, Xianhong Jiang, Jing Yang, Ya Wu, Jia Shi, Xiaoyang Wu, Shihan Du, Yuan Zhang, Lirong Gong, Shuan Dong, Jianbo Yu. Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-κB pathway.
Pharmaceutical biology.
2024 Dec; 62(1):22-32. doi:
10.1080/13880209.2023.2292256. [PMID: 38100537] - Shiya Huang, Xueqian Huang, Xiaohui Wen, Xuehong Liu, Hongxia Ma, Linling Xie, Yishu Wang, Shanjia Liu, Yongge Guan, Kunyin Li. Enhanced glycolysis in the myometrium with ectopic endometrium of patients with adenomyosis: a preliminary study.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
2024 Dec; 40(1):2332411. doi:
10.1080/09513590.2024.2332411. [PMID: 38537663] - Jing Li, Litao Zhang, Wenjie Yu, Mengjie Zhang, Feng Chen, Jianguo Liu. Mitochondrial alternative oxidase pathway accelerates non-motile cell germination by enhancing respiratory carbon metabolism and maintaining redox poise in Haematococcus pluvialis.
Bioresource technology.
2024 Jun; 402(?):130729. doi:
10.1016/j.biortech.2024.130729. [PMID: 38657826] - Maike Cosse, Tanja Rehders, Jürgen Eirich, Iris Finkemeier, Jennifer Selinski. Cysteine oxidation as a regulatory mechanism of Arabidopsis plastidial NAD-dependent malate dehydrogenase.
Physiologia plantarum.
2024 May; 176(3):e14340. doi:
10.1111/ppl.14340. [PMID: 38741259] - Anchal Garg, Payal Srivastava, Praveen Chandra Verma, Sumit Ghosh. ApCPS2 contributes to medicinal diterpenoid biosynthesis and defense against insect herbivore in Andrographis paniculata.
Plant science : an international journal of experimental plant biology.
2024 May; 342(?):112046. doi:
10.1016/j.plantsci.2024.112046. [PMID: 38395069] - Quan Ma, Jianzhao Liu, Hao Hu, Zisheng Luo. The uncharted territory of NAD+-capped RNA.
Trends in cell biology.
2024 May; 34(5):355-359. doi:
10.1016/j.tcb.2023.12.005. [PMID: 38242774] - Lijie Gu, Yanhong Du, Jianglei Chen, Mohammad Nazmul Hasan, Yung Dai Clayton, David J Matye, Jacob E Friedman, Tiangang Li. Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance.
Proceedings of the National Academy of Sciences of the United States of America.
2024 Apr; 121(17):e2320934121. doi:
10.1073/pnas.2320934121. [PMID: 38630726] - Ritamaria Di Lorenzo, Danila Falanga, Lucia Ricci, Antonio Colantuono, Giovanni Greco, Maura Angelillo, Fiorella Nugnes, Teresa Di Serio, Dorothea Costa, Annalisa Tito, Sonia Laneri. NAD-Driven Sirtuin Activation by Cordyceps sinensis Extract: Exploring the Adaptogenic Potential to Promote Skin Longevity.
International journal of molecular sciences.
2024 Apr; 25(8):. doi:
10.3390/ijms25084282. [PMID: 38673866] - Wenjing Ouyang, Emilie Wientjes, Peter E L van der Putten, Ludovico Caracciolo, Ruixuan Zhao, Collins Agho, Maurizio Junior Chiurazzi, Marius Bongers, Paul C Struik, Herbert van Amerongen, Xinyou Yin. Roles for leakiness and O2 evolution in explaining lower-than-theoretical quantum yields of photosynthesis in the PEP-CK subtype of C4 plants.
The New phytologist.
2024 Apr; 242(2):431-443. doi:
10.1111/nph.19614. [PMID: 38406986] - Parimalan Rangan, Agnelo Furtado, Viswanathan Chinnusamy, Robert Henry. A multi-cell model for the C4 photosynthetic pathway in developing wheat grains based upon tissue-specific transcriptome data.
Bio Systems.
2024 Apr; 238(?):105195. doi:
10.1016/j.biosystems.2024.105195. [PMID: 38555052] - Emily A Pinheiro, Jean-Marc DeKeyser, Brian Lenny, Yadav Sapkota, Paul W Burridge. Nilotinib-induced alterations in endothelial cell function recapitulate clinical vascular phenotypes independent of ABL1.
Scientific reports.
2024 03; 14(1):7123. doi:
10.1038/s41598-024-57686-8. [PMID: 38532120] - Ke Wang, Xueqing Liu, Kevin K Y Hu, Victoria S Haritos. Artificial Methylotrophic Cells via Bottom-Up Integration of a Methanol-Utilizing Pathway.
ACS synthetic biology.
2024 Mar; 13(3):888-900. doi:
10.1021/acssynbio.3c00683. [PMID: 38359048] - Franziska Gütgemann, Annet Heuvelink, Anja Müller, Yury Churin, Rianne Buter, Arne Jung, Anneke Feberwee, Jeanine Wiegel, Franziska Kumm, Ann Sophie Braun, Min Yue, Edgardo Soriano-Vargas, Stefan Swanepoel, Nadine Botteldoorn, Miranda Kirchner, Corinna Kehrenberg. Recommendation of a standardized broth microdilution method for antimicrobial susceptibility testing of Avibacterium paragallinarum and resistance monitoring.
Journal of clinical microbiology.
2024 Mar; 62(3):e0101123. doi:
10.1128/jcm.01011-23. [PMID: 38363142] - Xufeng Wang, Dongli Yu, Jiancheng Yu, Hao Hu, Runlai Hang, Zachary Amador, Qi Chen, Jijie Chai, Xuemei Chen. Toll/interleukin-1 receptor (TIR) domain-containing proteins have NAD-RNA decapping activity.
Nature communications.
2024 Mar; 15(1):2261. doi:
10.1038/s41467-024-46499-y. [PMID: 38480720] - Wen Song, Li Liu, Dongli Yu, Hanna Bernardy, Jan Jirschitzka, Shijia Huang, Aolin Jia, Wictoria Jemielniak, Julia Acker, Henriette Laessle, Junli Wang, Qiaochu Shen, Weijie Chen, Pilong Li, Jane E Parker, Zhifu Han, Paul Schulze-Lefert, Jijie Chai. Substrate-induced condensation activates plant TIR domain proteins.
Nature.
2024 Mar; 627(8005):847-853. doi:
10.1038/s41586-024-07183-9. [PMID: 38480885] - Yuho Kim, Hailey A Parry, T Bradley Willingham, Greg Alspaugh, Eric Lindberg, Christian A Combs, Jay R Knutson, Christopher K E Bleck, Brian Glancy. Reorganization of mitochondria-organelle interactions during postnatal development in skeletal muscle.
The Journal of physiology.
2024 Mar; 602(5):891-912. doi:
10.1113/jp285014. [PMID: 38429930] - Claire McDonald, Craig Alderson, Matthew G Birkbeck, Laura Brown, Silvia Del Din, Grainne G Gorman, Kieren Hollingsworth, Clare Massarella, Rana Rehman, Lynn Rochester, Avan Ap Sayer, Huizhong Su, Helen Tuppen, Charlotte Warren, Miles D Witham. A study protocol to investigate if acipimox improves muscle function and sarcopenia: an open-label, uncontrolled, before-and-after experimental medicine feasibility study in community-dwelling older adults.
BMJ open.
2024 Feb; 14(2):e076518. doi:
10.1136/bmjopen-2023-076518. [PMID: 38417968] - Di-Yang Sun, Wen-Bin Wu, Jian-Jin Wu, Yu Shi, Jia-Jun Xu, Shen-Xi Ouyang, Chen Chi, Yi Shi, Qing-Xin Ji, Jin-Hao Miao, Jiang-Tao Fu, Jie Tong, Ping-Ping Zhang, Jia-Bao Zhang, Zhi-Yong Li, Le-Feng Qu, Fu-Ming Shen, Dong-Jie Li, Pei Wang. Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Nature communications.
2024 Feb; 15(1):1429. doi:
10.1038/s41467-024-45823-w. [PMID: 38365899] - Qinghai Qiao, Xin Wang, Zhiyuan Su, Chenyang Han, Keke Zhao, Kaijie Qi, Zhihua Xie, Xiaosan Huang, Shaoling Zhang. PuNDH9, a subunit of ETC Complex I regulates plant defense by interacting with PuPR1.
Plant science : an international journal of experimental plant biology.
2024 Feb; ?(?):112009. doi:
10.1016/j.plantsci.2024.112009. [PMID: 38316345] - Xiaojing Wei, Yutian Tan, Jiaqi Huang, Ximing Dong, Weijie Feng, Tanglin Liu, Zhao Yang, Guiying Yang, Xiao Luo. N1-methylnicotinamide impairs gestational glucose tolerance in mice.
Journal of molecular endocrinology.
2024 Feb; 72(2):. doi:
10.1530/jme-23-0126. [PMID: 38029302] - Josephine Yu, Neil A Youngson, D Ross Laybutt, Margaret J Morris, Sarah-Jane Leigh. Complementary yet divergent effects of exercise and an exercise mimetic on microbiome in high-fat diet-induced obesity.
Physiological genomics.
2024 Feb; 56(2):136-144. doi:
10.1152/physiolgenomics.00066.2023. [PMID: 38009223] - Xi Chen, Zhenchuan Wang, Chen Li, Zhao Zhang, Shan Lu, Xuanzhong Wang, Qi Liang, Xiaoxi Zhu, Chengliang Pan, Qingxuan Wang, Zhilin Ji, Yubo Wang, Meihua Piao, Guangfan Chi, Pengfei Ge. SIRT1 activated by AROS sensitizes glioma cells to ferroptosis via induction of NAD+ depletion-dependent activation of ATF3.
Redox biology.
2024 Feb; 69(?):103030. doi:
10.1016/j.redox.2024.103030. [PMID: 38181705] - Mei-Yu Zhang, Xin-Ru Xu, Ru-Ping Zhao, Chao Huang, Yuan-Da Song, Zi-Tong Zhao, Yu-Bin Zhao, Xiao-Jie Ren, Xin-He Zhao. Mechanism of enhanced microalgal biomass and lipid accumulation through symbiosis between a highly succinic acid-producing strain of Escherichia coli SUC and Aurantiochytrium sp. SW1.
Bioresource technology.
2024 Feb; 394(?):130232. doi:
10.1016/j.biortech.2023.130232. [PMID: 38141881] - Hao Yu, Daojing Gan, Zhen Luo, Qilin Yang, Dongqi An, Hao Zhang, Yingchun Hu, Zhuang Ma, Qingchun Zeng, Dingli Xu, Hao Ren. α-Ketoglutarate improves cardiac insufficiency through NAD+-SIRT1 signaling-mediated mitophagy and ferroptosis in pressure overload-induced mice.
Molecular medicine (Cambridge, Mass.).
2024 Jan; 30(1):15. doi:
10.1186/s10020-024-00783-1. [PMID: 38254035] - Tonghui Wang, Jinbo Fei, Zhenzhen Dong, Fanchen Yu, Junbai Li. Nanoarchitectonics with a Membrane-Embedded Electron Shuttle Mimics the Bioenergy Anabolism of Mitochondria.
Angewandte Chemie (International ed. in English).
2024 Jan; ?(?):e202319116. doi:
10.1002/anie.202319116. [PMID: 38225920] - Limin Liu, Yulin Ye, Rui Lin, Tianyu Liu, Sinan Wang, Zelin Feng, Xiaoli Wang, Hailong Cao, Xin Chen, Junming Miao, Yifei Liu, Kui Jiang, Zhibo Han, Zongjin Li, Xiaocang Cao. Ferroptosis: a promising candidate for exosome-mediated regulation in different diseases.
Cell communication and signaling : CCS.
2024 01; 22(1):6. doi:
10.1186/s12964-023-01369-w. [PMID: 38166927] - Shan Shen, Mingyang Shen, Lirun Kuang, Keyu Yang, Shiran Wu, Xinde Liu, Yuting Wang, Yong Wang. SIRT1/SREBPs-mediated regulation of lipid metabolism.
Pharmacological research.
2024 Jan; 199(?):107037. doi:
10.1016/j.phrs.2023.107037. [PMID: 38070792] - Edgar Willibaldo Allebrandt Neto, Jadyellen Rondon E Silva, Stephanie Figueiredo Santos, Suélem Aparecida de França Lemes, Nair Honda Kawashita, Mayara Peron Pereira. The futile creatine cycle and the synthesis of fatty acids in inguinal white adipose tissue from growing rats, submitted to a hypoprotein-hyperglycidic diet for 15 days.
Lipids.
2024 Jan; 59(1):3-12. doi:
10.1002/lipd.12384. [PMID: 38223990] - Chaomurilege, Atsuko Miyagi, Toshiki Ishikawa, Masatoshi Yamaguchi, Hideki Murayama, Maki Kawai-Yamada. Metabolic changes associated with dark-induced leaf senescence in Arabidopsis nadk2 mutants.
Plant signaling & behavior.
2023 12; 18(1):2215618. doi:
10.1080/15592324.2023.2215618. [PMID: 37272565] - Chao Dai, Mengqian Hou, Xudong Yang, Zhefeng Wang, Changpo Sun, Xin Wu, Shujin Wang. Increased NAD+ levels protect female mouse reproductive system against zearalenone-impaired glycolysis, lipid metabolism, antioxidant capacity and inflammation.
Reproductive toxicology (Elmsford, N.Y.).
2023 Dec; 124(?):108530. doi:
10.1016/j.reprotox.2023.108530. [PMID: 38159578] - Liwen Gao, Xi Huang, Ruyu Deng, Shanshan Wu, Yu Peng, Guoliang Xiong, Jiandong Lu, Xinhui Liu. Jian-Pi-Yi-Shen formula alleviates renal fibrosis by restoring NAD+ biosynthesis in vivo and in vitro.
Aging.
2023 Dec; 16(1):106-128. doi:
10.18632/aging.205352. [PMID: 38157259] - Dan Sun, Guohua Qi, Xuan Yi, Hongyan Zhu, Yongdong Jin. Smart Ratiometric SERS Nanoprobe for Real-Time Monitoring Hydrogen Peroxide in Living Cells during NADH Treatment Associated with Ferroptosis.
Analytical chemistry.
2023 Dec; 95(49):18075-18081. doi:
10.1021/acs.analchem.3c02912. [PMID: 38030577] - Katayoun Zamani, Motahhareh Mohsenpour, Mohammad Ali Malboobi. Predicting the allergenic risk of Phosphite-NAD+-Oxidoreductase and purple acid phosphatase 17 proteins in genetically modified canola using bioinformatic approaches.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2023 Dec; 182(?):114094. doi:
10.1016/j.fct.2023.114094. [PMID: 37925014] - Lili Cheng, R N V Krishna Deepak, Guoqiang Wang, Ziyi Meng, Lei Tao, Mengqing Xie, Wenna Chi, Yuming Zhang, Mingming Yang, Yilie Liao, Ruiqun Chen, Yu Liang, Junyu Zhang, Yuedong Huang, Weihua Wang, Zhiying Guo, Yunfang Wang, Jiandie D Lin, Hao Fan, Ligong Chen. Hepatic mitochondrial NAD + transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis.
Hepatology (Baltimore, Md.).
2023 Dec; 78(6):1828-1842. doi:
10.1097/hep.0000000000000314. [PMID: 36804859] - Mikako Yagi, Yura Do, Haruka Hirai, Kenji Miki, Takahiro Toshima, Yukina Fukahori, Daiki Setoyama, Chiaki Abe, Yo-Ichi Nabeshima, Dongchon Kang, Takeshi Uchiumi. Improving lysosomal ferroptosis with NMN administration protects against heart failure.
Life science alliance.
2023 Dec; 6(12):. doi:
10.26508/lsa.202302116. [PMID: 37793777] - Alise Zagare, German Preciat, Sarah L Nickels, Xi Luo, Anna S Monzel, Gemma Gomez-Giro, Graham Robertson, Christian Jaeger, Jafar Sharif, Haruhiko Koseki, Nico J Diederich, Enrico Glaab, Ronan M T Fleming, Jens C Schwamborn. Omics data integration suggests a potential idiopathic Parkinson's disease signature.
Communications biology.
2023 11; 6(1):1179. doi:
10.1038/s42003-023-05548-w. [PMID: 37985891] - Xing Gao, Lele Jian, Lijun Zhang, Yuqiao Xu, Yuanlin Zhao, Ying Yang, Yuan Yuan, Yuying Wang, Shenhui Xu, Bincheng Ren, Zimeng Li, Chao Wang, Jing Li, Yu Gu, Jing Ye. Perilipin 5 protects the mitochondrial oxidative functions and improves the alcoholic liver injury in mice.
Liver international : official journal of the International Association for the Study of the Liver.
2023 Nov; ?(?):. doi:
10.1111/liv.15775. [PMID: 37933091] - Shoki Ito, Atsuko Watanabe, Takashi Osanai. Regulation of l-aspartate oxidase contributes to NADP+ biosynthesis in Synechocystis sp. PCC 6803.
Plant physiology.
2023 Nov; ?(?):. doi:
10.1093/plphys/kiad580. [PMID: 37936332] - Huijuan Zhou, Mingshen Su, Jihong Du, Xianan Zhang, Xiongwei Li, Minghao Zhang, Yang Hu, Chen Huan, Zhengwen Ye. Crucial roles of sorbitol metabolism and energy status in the chilling tolerance of yellow peach.
Plant physiology and biochemistry : PPB.
2023 Nov; 204(?):108092. doi:
10.1016/j.plaphy.2023.108092. [PMID: 37852068] - Toshitaka Nakamura, Eikan Mishima, Naoya Yamada, André Santos Dias Mourão, Dietrich Trümbach, Sebastian Doll, Jonas Wanninger, Elena Lytton, Peter Sennhenn, Thamara Nishida Xavier da Silva, José Pedro Friedmann Angeli, Michael Sattler, Bettina Proneth, Marcus Conrad. Integrated chemical and genetic screens unveil FSP1 mechanisms of ferroptosis regulation.
Nature structural & molecular biology.
2023 Nov; 30(11):1806-1815. doi:
10.1038/s41594-023-01136-y. [PMID: 37957306] - Eeva M Marttinen, Eva L Decker, Petra Heinonen, Ralf Reski, Jari P T Valkonen. Putative NAD(P)-Binding Rossmann Fold Protein Is Involved in Chitosan-Induced Peroxidase Activity and Lipoxygenase Expression in Physcomitrium patens.
Molecular plant-microbe interactions : MPMI.
2023 Nov; 36(11):682-692. doi:
10.1094/mpmi-07-23-0094-r. [PMID: 37486175] - Agata Jacewicz, Swathi Dantuluri, Stewart Shuman. Structural basis for Tpt1-catalyzed 2'-PO4 transfer from RNA and NADP(H) to NAD.
Proceedings of the National Academy of Sciences of the United States of America.
2023 Oct; 120(44):e2312999120. doi:
10.1073/pnas.2312999120. [PMID: 37883434] - Jinxing Du, Jiaqi Shao, Shengjie Li, Tao Zhu, Hongmei Song, Caixia Lei, Meng Zhang, Yingkun Cen. Integrated transcriptomic and proteomic analyses reveal the mechanism of easy acceptance of artificial pelleted diets during food habit domestication in Largemouth bass (Micropterus salmoides).
Scientific reports.
2023 10; 13(1):18461. doi:
10.1038/s41598-023-45645-8. [PMID: 37891233] - Qi Li, Mingxi Zhou, Shweta Chhajed, Fahong Yu, Sixue Chen, Yanping Zhang, Zhonglin Mou. N-hydroxypipecolic acid triggers systemic acquired resistance through extracellular NAD(P).
Nature communications.
2023 Oct; 14(1):6848. doi:
10.1038/s41467-023-42629-0. [PMID: 37891163] - Ashkan Kalantary-Charvadeh, Saeed Nazari Soltan Ahmad, Somayeh Aslani, Mehdi Beyrami, Mehran Mesgari-Abbasi. β-lapachone protects against doxorubicin-induced hepatotoxicity through modulation of NAD+ /SIRT-1/FXR/p-AMPK/NF-kB and Nrf2 signaling axis.
Journal of biochemical and molecular toxicology.
2023 Oct; ?(?):e23564. doi:
10.1002/jbt.23564. [PMID: 37867446] - Hsiang Chang, Yen-Ting Chen, Hsiang-En Huang, Mang-Jye Ger. Overexpressing plant ferredoxin-like protein enhances photosynthetic efficiency and carbohydrates accumulation in Phalaenopsis.
Transgenic research.
2023 Oct; ?(?):. doi:
10.1007/s11248-023-00370-w. [PMID: 37851307] - Mengdi Chen, Zhengbo Wang, Ziyuan Hao, Hongying Li, Qi Feng, Xue Yang, Xiaojiao Han, Xiping Zhao. Screening and Validation of Appropriate Reference Genes for Real-Time Quantitative PCR under PEG, NaCl and ZnSO4 Treatments in Broussonetia papyrifera.
International journal of molecular sciences.
2023 Oct; 24(20):. doi:
10.3390/ijms242015087. [PMID: 37894768] - Shivansh Goyal, Akhilesh Paspureddi, Mu-Jie Lu, Hsin-Ru Chan, Scott N Lyons, Crystal N Wilson, Marc Niere, Mathias Ziegler, Xiaolu A Cambronne. Dynamics of SLC25A51 reveal preference for oxidized NAD+ and substrate led transport.
EMBO reports.
2023 10; 24(10):e56596. doi:
10.15252/embr.202256596. [PMID: 37575034] - Mahmoud M A Abulmeaty, Hazem K Ghneim, Ali Madi Almajwal, Suhail Razak, Abdulaziz S AlSahli, Juan E Andrade Laborde, Ebtesam M Ibrahim, Mourad A M Aboul-Soud, Yazeed A Al-Sheikh. Effects of unpredictable chronic mild stress on the cellular redox state and mitochondrial energy homeostasis in rat adipose tissue: A comprehensive metabolic study.
Cell biochemistry and function.
2023 Oct; ?(?):. doi:
10.1002/cbf.3867. [PMID: 37805950] - Motohiro Sekiya, Kenta Kainoh, Kenji Saito, Daichi Yamazaki, Tomomi Tsuyuzaki, Wanpei Chen, Yuto Kobari, Ayumi Nakata, Haruka Babe, Hitoshi Shimano. C-Terminal Binding Protein 2 Emerges as a Critical Player Linking Metabolic Imbalance to the Pathogenesis of Obesity.
Journal of atherosclerosis and thrombosis.
2023 Oct; ?(?):. doi:
10.5551/jat.rv22014. [PMID: 37793810] - Jooseung Hyeon, Jihan Lee, Eunju Kim, Hyeong Min Lee, Kwang Pyo Kim, Jaejin Shin, Hyung Soon Park, Yun-Il Lee, Chang-Hoon Nam. Vutiglabridin exerts anti-ageing effects in aged mice through alleviating age-related metabolic dysfunctions.
Experimental gerontology.
2023 10; 181(?):112269. doi:
10.1016/j.exger.2023.112269. [PMID: 37567452] - Xiaofei Yang, Dechang Cao. DXO gears mRNA with alternative NAD and m7G caps.
Trends in plant science.
2023 10; 28(10):1083-1085. doi:
10.1016/j.tplants.2023.06.003. [PMID: 37357082] - Myrthe A J Smits, Bauke V Schomakers, Michel van Weeghel, Eric J M Wever, Rob C I Wüst, Frederike Dijk, Georges E Janssens, Mariëtte Goddijn, Sebastiaan Mastenbroek, Riekelt H Houtkooper, Geert Hamer. Human ovarian aging is characterized by oxidative damage and mitochondrial dysfunction.
Human reproduction (Oxford, England).
2023 Sep; ?(?):. doi:
10.1093/humrep/dead177. [PMID: 37671592] - Shun Watanabe, Riki Haruyama, Koji Umezawa, Ikuo Tomioka, Soichiro Nakamura, Shigeru Katayama, Takakazu Mitani. Genistein enhances NAD+ biosynthesis by upregulating nicotinamide phosphoribosyltransferase in adipocytes.
The Journal of nutritional biochemistry.
2023 Aug; 121(?):109433. doi:
10.1016/j.jnutbio.2023.109433. [PMID: 37648097] - Ivan Kushkevych, Dani Dordević, Mohammad I Alberfkani, Márió Gajdács, Eszter Ostorházi, Monika Vítězová, Simon K-M R Rittmann. NADH and NADPH peroxidases as antioxidant defense mechanisms in intestinal sulfate-reducing bacteria.
Scientific reports.
2023 08; 13(1):13922. doi:
10.1038/s41598-023-41185-3. [PMID: 37626119] - Luís F Grilo, João D Martins, Mariana S Diniz, Carolina Tocantins, Chiara H Cavallaro, Inês Baldeiras, Teresa Cunha-Oliveira, Stephen Ford, Peter W Nathanielsz, Paulo J Oliveira, Susana P Pereira. Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress.
Clinical science (London, England : 1979).
2023 Aug; ?(?):. doi:
10.1042/cs20230048. [PMID: 37565250] - Ke Jiang, Ruoxuan Bai, Ting Gao, Ping Lu, Jingya Zhang, Shuting Zhang, Fangxu Xu, Shenghou Wang, Hongxin Zhao. Optimization of hydrogen production in Enterobacter aerogenes by Complex I peripheral fragments destruction and maeA overexpression.
Microbial cell factories.
2023 Jul; 22(1):137. doi:
10.1186/s12934-023-02155-6. [PMID: 37496040] - Superior Syngkli, Bidyadhar Das. Purification and characterization of human glycerol 3-phosphate dehydrogenases (mitochondrial and cytosolic) by NAD+/NADH redox method.
Biochimie.
2023 Jul; ?(?):. doi:
10.1016/j.biochi.2023.07.015. [PMID: 37481063] - Meng-Fei Guo, Jing Zhou, Huan-Huan Zhang, Ping Zhong, Jin-Di Xu, Shan-Shan Zhou, Fang Long, He Zhu, Qian Mao, Song-Lin Li. UPLC-QTOF-MS/MS assisted UPLC-TQ-MS/MS strategy to comparatively investigate the rat pharmacokinetics of N-acetyldopamine oligomers derived from Cicadae Periostracum.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2023 Jul; 1226(?):123806. doi:
10.1016/j.jchromb.2023.123806. [PMID: 37348161] - Marta Grzechowiak, Joanna Sliwiak, Mariusz Jaskolski, Milosz Ruszkowski. Structural and functional studies of Arabidopsis thaliana glutamate dehydrogenase isoform 2 demonstrate enzyme dynamics and identify its calcium binding site.
Plant physiology and biochemistry : PPB.
2023 Jul; 201(?):107895. doi:
10.1016/j.plaphy.2023.107895. [PMID: 37478728] - Megan E Mitchell, Petia Z Gatzeva-Topalova, Austin D Bargmann, Tarek Sammakia, Marcelo C Sousa. Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance.
Biochemistry.
2023 Jul; ?(?):. doi:
10.1021/acs.biochem.3c00227. [PMID: 37410993] - Mustafa N Okur, Burcin Duan Sahbaz, Risako Kimura, Uri Manor, Jaimin Patel, Jae-Hyeon Park, Leo Andrade, Chandrakala Puligilla, Deborah L Croteau, Vilhelm A Bohr. Long-term NAD+ supplementation prevents the progression of age-related hearing loss in mice.
Aging cell.
2023 Jul; ?(?):. doi:
10.1111/acel.13909. [PMID: 37395319] - Toshitaka Nakamura, Clara Hipp, André Santos Dias Mourão, Jan Borggräfe, Maceler Aldrovandi, Bernhard Henkelmann, Jonas Wanninger, Eikan Mishima, Elena Lytton, David Emler, Bettina Proneth, Michael Sattler, Marcus Conrad. Phase separation of FSP1 promotes ferroptosis.
Nature.
2023 Jul; 619(7969):371-377. doi:
10.1038/s41586-023-06255-6. [PMID: 37380771] - Ziyu Zhu, Xiaoqian Chen, Wenhao Li, Yingping Zhuang, Yuzheng Zhao, Guan Wang. Understanding the effect of temperature downshift on CHO cell growth, antibody titer and product quality by intracellular metabolite profiling and in vivo monitoring of redox state.
Biotechnology progress.
2023 Jul; 39(4):e3352. doi:
10.1002/btpr.3352. [PMID: 37141532] - Huong Duong, Shannon Fullbrook, Kate Reddington, Elizabeth Minogue, Thomas Barry. Design, Development, and Validation of a Culture-Independent Nucleic Acid Diagnostics Method for the Rapid Detection and Quantification of the Burkholderia cepacia Complex in Water with an Equivalence to ISO/TS 12869:2019.
PDA journal of pharmaceutical science and technology.
2023 Jul; 77(4):296-310. doi:
10.5731/pdajpst.2021.012728. [PMID: 36822644] - Zongwen Wang, Xiating Li, Feng Zhang, Yu Gao, Jintian Cheng, FengFu Fu. Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides.
Analytical chemistry.
2023 Jun; ?(?):. doi:
10.1021/acs.analchem.3c01928. [PMID: 37382204] - Yulu Ran, Qingzhuoma Yang, Jie Zeng, Fazhi Li, Yu Cao, Qingrui Xu, Dairong Qiao, Hui Xu, Yi Cao. Potential xylose transporters regulated by CreA improved lipid yield and furfural tolerance in oleaginous yeast Saitozyma podzolica zwy-2-3.
Bioresource technology.
2023 Jun; ?(?):129413. doi:
10.1016/j.biortech.2023.129413. [PMID: 37390935] - Shalender Bhasin, Douglas Seals, Marie Migaud, Nicolas Musi, Joseph A Baur. Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns.
Endocrine reviews.
2023 Jun; ?(?):. doi:
10.1210/endrev/bnad019. [PMID: 37364580] - Naveen J Roy, Shreyada N Save, Virenderkumar Sharma, Benchamin Abraham, Abhijith Kuttanamkuzhi, Shilpy Sharma, Mayurika Lahiri, Pinaki Talukdar. NAD(P)H:Quinone Acceptor Oxidoreductase 1 (NQO1) Activatable Salicylamide H+/Cl- Transporters.
Chemistry (Weinheim an der Bergstrasse, Germany).
2023 Jun; ?(?):e202301412. doi:
10.1002/chem.202301412. [PMID: 37345998] - Serhii Chornyi, Cláudio F Costa, Lodewijk IJlst, Marc Fransen, Ronald J A Wanders, Carlo W T van Roermund, Hans R Waterham. Human peroxisomal NAD+/NADH homeostasis is regulated by two independent NAD(H) shuttle systems.
Free radical biology & medicine.
2023 Jun; 206(?):22-32. doi:
10.1016/j.freeradbiomed.2023.06.020. [PMID: 37355054] - Tomasz Piechowiak, Bartosz Skóra, Maciej Balawejder. Effect of postharvest nicotinamide treatment on NAD+ metabolism and redox status in strawberry fruit during storage.
Phytochemistry.
2023 Jun; 213(?):113766. doi:
10.1016/j.phytochem.2023.113766. [PMID: 37343736] - Jan L Krüsemann, Vittorio Rainaldi, Charles Ar Cotton, Nico J Claassens, Steffen N Lindner. The cofactor challenge in synthetic methylotrophy: bioengineering and industrial applications.
Current opinion in biotechnology.
2023 Jun; 82(?):102953. doi:
10.1016/j.copbio.2023.102953. [PMID: 37320962] - Na Yang, Runbin Sun, Xiaoli Zhang, Jing Wang, Lulu Wang, Huaijun Zhu, Man Yuan, Yifan Xu, Chun Ge, Jun He, Min Wang. Alternative pathway of bile acid biosynthesis contributes to ameliorate NASH after induction of NAMPT/NAD+/SIRT1 axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Jun; 164(?):114987. doi:
10.1016/j.biopha.2023.114987. [PMID: 37315437] - Jun Guo, Long Chen, Min Ma. Ginsenoside Rg1 Suppresses Ferroptosis of Renal Tubular Epithelial Cells in Sepsis-induced Acute Kidney Injury via the FSP1-CoQ10-NAD(P)H Pathway.
Current medicinal chemistry.
2023 Jun; ?(?):. doi:
10.2174/0929867330666230607125054. [PMID: 37287288] - Jie Yu, Bingling Zhong, Lin Zhao, Ying Hou, Nana Ai, Jin-Jian Lu, Wei Ge, Xiuping Chen. Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
2023 Jun; 70(?):100977. doi:
10.1016/j.drup.2023.100977. [PMID: 37321064] - David M Dinh, Leonard M Thomas, Elizabeth A Karr. Crystal structure of a putative 3-hydroxypimelyl-CoA dehydrogenase, Hcd1, from Syntrophus aciditrophicus strain SB at 1.78 Å resolution.
Acta crystallographica. Section F, Structural biology communications.
2023 Jun; ?(?):. doi:
10.1107/s2053230x23004399. [PMID: 37227375] - Hong Yang, Xiangyu Li, Han Jin, Hasan Turkez, Gurkan Ozturk, Hamdi Levent Doganay, Cheng Zhang, Jens Nielsen, Mathias Uhlén, Jan Borén, Adil Mardinoglu. Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators.
Free radical biology & medicine.
2023 May; ?(?):. doi:
10.1016/j.freeradbiomed.2023.05.013. [PMID: 37245532] - Qing Song, Jun Wang, Alexandra Griffiths, Samuel Man Lee, Iredia D Iyamu, Rong Huang, Jose Cordoba-Chacon, Zhenyuan Song. Nicotinamide N-methyltransferase (NNMT) upregulation contributes to palmitate-elicited PPARγ transactivation in hepatocytes.
American journal of physiology. Cell physiology.
2023 May; ?(?):. doi:
10.1152/ajpcell.00010.2023. [PMID: 37212549] - Ju-Yi Hsieh, Kun-Chi Chen, Chun-Hsiung Wang, Guang-Yaw Liu, Jie-An Ye, Yu-Tung Chou, Yi-Chun Lin, Cheng-Jhe Lyu, Rui-Ying Chang, Yi-Liang Liu, Yen-Hsien Li, Mau-Rong Lee, Meng-Chiao Ho, Hui-Chih Hung. Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration.
Communications biology.
2023 May; 6(1):548. doi:
10.1038/s42003-023-04930-y. [PMID: 37217557] - Yanqiu Yang, Ru Chen, Yue Che, Xiaohu Yao, Mingxia Fang, Yingjie Wang, Di Zhou, Ning Li, Yue Hou. Isoamericanin A improves lipopolysaccharide-induced memory impairment in mice through suppression of the nicotinamide adenine dinucleotide phosphateoxidase-dependent nuclear factor kappa B signaling pathway.
Phytotherapy research : PTR.
2023 May; ?(?):. doi:
10.1002/ptr.7858. [PMID: 37209001] - Lamia Sakouhi, Oumayma Kadri, Sirine Werghi, Marouane Ben Massoud, Oussama Kharbech, Yoshiyuki Murata, Abdelilah Chaoui. Seed pretreatment with melatonin confers cadmium tolerance to chickpea seedlings through cellular redox homeostasis and antioxidant gene expression improvement.
Environmental science and pollution research international.
2023 May; ?(?):. doi:
10.1007/s11356-023-27562-5. [PMID: 37191750] - Qi Ding, Ke Wen, Qian Li, Qi-Hang Zhao, Jia-Le Zhao, Yun-Fei Xiao, Xiao-Hui Guan, Mei-Xiu Jiang, Feng Zhang, Lingfang Wang. CD38 deficiency promotes skeletal muscle and brown adipose tissue energy expenditure through activating NAD+-Sirt1-PGC1α signaling pathway.
Canadian journal of physiology and pharmacology.
2023 May; ?(?):. doi:
10.1139/cjpp-2022-0454. [PMID: 37192549] - Jongsu Jeon, Dohyun Lee, Bobae Kim, Bo-Yoon Park, Chang Joo Oh, Min-Ji Kim, Jae-Han Jeon, In-Kyu Lee, Onyu Park, Seoyeong Baek, Chae Won Lim, Dongryeol Ryu, Sungsoon Fang, Johan Auwerx, Kyong-Tai Kim, Hoe-Yune Jung. CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice.
Diabetes & metabolism journal.
2023 Apr; ?(?):. doi:
10.4093/dmj.2022.0244. [PMID: 37098411] - Cong-Hui Yao, Joon Seok Park, Kiran Kurmi, Song-Hua Hu, Giulia Notarangelo, Joseph Crowley, Heidi Jacobson, Sheng Hui, Arlene H Sharpe, Marcia C Haigis. Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis.
Molecular cell.
2023 04; 83(8):1340-1349.e7. doi:
10.1016/j.molcel.2023.03.023. [PMID: 37084714] - Salvatore Nesci, Cristina Algieri, Fabiana Trombetti, Micaela Fabbri, Giorgio Lenaz. Two separate pathways underlie NADH and succinate oxidation in swine heart mitochondria: Kinetic evidence on the mobile electron carriers.
Biochimica et biophysica acta. Bioenergetics.
2023 Apr; 1864(3):148977. doi:
10.1016/j.bbabio.2023.148977. [PMID: 37059413] - Xin Liu, Liwen Wang, Tsokyi Choera, Xin Fang, Gang Wang, Wenhua Chen, Yin-Won Lee, Sherif Ramzy Mohamed, Dawood H Dawood, Jianrong Shi, Jianhong Xu, Nancy P Keller. Paralogous FgIDO genes with differential roles in tryptophan catabolism, fungal development and virulence in Fusarium graminearum.
Microbiological research.
2023 Apr; 272(?):127382. doi:
10.1016/j.micres.2023.127382. [PMID: 37030080] - Viviane Cacefo, Alessandra Ferreira Ribas, Luiz Gonzaga Esteves Vieira. Proline metabolism as a mechanism for the energy dissipation in VaP5CSF129A transgenic tobacco plants under water deficit.
Journal of plant physiology.
2023 Apr; 283(?):153964. doi:
10.1016/j.jplph.2023.153964. [PMID: 36917876] - Chaitra Surugihalli, Vaishna Muralidaran, Caitlin E Ryan, Kruti Patel, David Zhao, Nishanth E Sunny. Branched-chain amino acids alter cellular redox to induce lipid oxidation and reduce de novo lipogenesis in the liver.
American journal of physiology. Endocrinology and metabolism.
2023 04; 324(4):E299-E313. doi:
10.1152/ajpendo.00307.2022. [PMID: 36791321] - Peng Lyu, Shengrong Li, Ying Han, Shengnan Shen, Zheling Feng, Piliang Hao, Zhengqiu Li, Ligen Lin. Affinity-based protein profiling-driven discovery of myricanol as a Nampt activator.
Bioorganic chemistry.
2023 04; 133(?):106435. doi:
10.1016/j.bioorg.2023.106435. [PMID: 36841049] - Jay Jethva, Sophie Lichtenauer, Romy Schmidt-Schippers, Anja Steffen-Heins, Gernot Poschet, Markus Wirtz, Joost T van Dongen, Jürgen Eirich, Iris Finkemeier, Wolfgang Bilger, Markus Schwarzländer, Margret Sauter. Mitochondrial alternative NADH dehydrogenases NDA1 and NDA2 promote survival of reoxygenation stress in Arabidopsis by safeguarding photosynthesis and limiting ROS generation.
The New phytologist.
2023 04; 238(1):96-112. doi:
10.1111/nph.18657. [PMID: 36464787] - Shota Suzuki, Daimu Tanaka, Atsuko Miyagi, Kentaro Takahara, Masaru Kono, Chaomurilege, Ko Noguchi, Toshiki Ishikawa, Minoru Nagano, Masatoshi Yamaguchi, Maki Kawai-Yamada. Loss of peroxisomal NAD kinase 3 (NADK3) affects photorespiration metabolism in Arabidopsis.
Journal of plant physiology.
2023 Apr; 283(?):153950. doi:
10.1016/j.jplph.2023.153950. [PMID: 36889102] - Olga A Fedotova, Elizaveta A Polyakova, Olga I Grabelnych. Ca2+-dependent oxidation of exogenous NADH and NADPH by the mitochondria of spring wheat and its relation with AOX capacity and ROS content at high temperatures.
Journal of plant physiology.
2023 Apr; 283(?):153943. doi:
10.1016/j.jplph.2023.153943. [PMID: 36841182] - Tasnim Arroum, Marie-Theres Borowski, Nico Marx, Frank Schmelter, Martin Scholz, Olympia Ekaterini Psathaki, Michael Hippler, José Antonio Enriquez, Karin B Busch. Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation.
Biological chemistry.
2023 Mar; ?(?):. doi:
10.1515/hsz-2022-0309. [PMID: 36952351] - Chen Guo, Qingxia Huang, Yisa Wang, Yao Yao, Jing Li, Jinjin Chen, Mingxia Wu, Zepeng Zhang, Mingyao E, Hongyu Qi, Peng Ji, Qing Liu, Daqing Zhao, Hang Su, Wenxiu Qi, Xiangyan Li. Therapeutic application of natural products: NAD+ metabolism as potential target.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2023 Mar; 114(?):154768. doi:
10.1016/j.phymed.2023.154768. [PMID: 36948143] - Kaiqing Ma, He Yang, Xingkang Wu, Fangjun Huo, Fangqin Cheng, Caixia Yin. An Activatable NIR Fluorescent Probe for NAD(P)H and Its Application to the Real-Time Monitoring of p53 Abnormalities In Vivo.
Angewandte Chemie (International ed. in English).
2023 Mar; ?(?):e202301518. doi:
10.1002/anie.202301518. [PMID: 36867115] - Xiaojing Wei, Chuanfei Wei, Yutian Tan, Ximing Dong, Zhao Yang, Jianqun Yan, Xiao Luo. Both prolonged high-fat diet consumption and calorie restriction boost hepatic NAD+ metabolism in mice.
The Journal of nutritional biochemistry.
2023 Feb; ?(?):109296. doi:
10.1016/j.jnutbio.2023.109296. [PMID: 36849030] - Lyon Bruinsma, Sebastian Wenk, Nico J Claassens, Vitor A P Martins Dos Santos. Paving the way for synthetic C1 - Metabolism in Pseudomonas putida through the reductive glycine pathway.
Metabolic engineering.
2023 Feb; ?(?):. doi:
10.1016/j.ymben.2023.02.004. [PMID: 36804222] - Michelle T Hulin, Lionel Hill, Jonathan D G Jones, Wenbo Ma. Pangenomic analysis reveals plant NAD+ manipulation as an important virulence activity of bacterial pathogen effectors.
Proceedings of the National Academy of Sciences of the United States of America.
2023 Feb; 120(7):e2217114120. doi:
10.1073/pnas.2217114120. [PMID: 36753463] - Yan Zhang, Wenjuan Zhu, Meng Wang, Pengjiao Xi, Haomin Wang, Derun Tian. Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high-fat diet.
IUBMB life.
2023 Feb; ?(?):. doi:
10.1002/iub.2707. [PMID: 36785893]