Flunixine (BioDeep_00000397896)

   


代谢物信息卡片


Flunixin Meglumine

化学式: C14H11F3N2O2 (296.07725819999996)
中文名称: 氟尼辛葡甲胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F
InChI: InChI=1S/C14H11F3N2O2/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12/h2-7H,1H3,(H,18,19)(H,20,21)

描述信息

C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3685
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
D058633 - Antipyretics

同义名列表

3 个代谢物同义名

Flunixin Meglumine; Flunixine; FLUNIXIN



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Enoch B de S Meira, Emily E Wiloch, Emma Nixon, James L Yeatts, Farha Ferdous Sheela, Geof W Smith, Ronald E Baynes. The pharmacokinetics of transdermal flunixin in lactating dairy goats. Journal of dairy science. 2022 Jan; 105(1):549-559. doi: 10.3168/jds.2021-20460. [PMID: 34656343]
  • Shubhashis Chakrabarty, Weilin L Shelver, David J Smith. Electrospray Ionization Inlet Tandem Mass Spectrometry: A Hyphenated Method for the Sensitive Determination of Chemicals in Animal Tissues and Body Fluids. Journal of the American Society for Mass Spectrometry. 2021 Jan; 32(1):14-20. doi: 10.1021/jasms.9b00114. [PMID: 33401917]
  • Emma Nixon, Alexandra R Carlson, Patricia A Routh, Liliana Hernandez, Glen W Almond, Ronald E Baynes, Kristen M Messenger. Comparative effects of nonsteroidal anti-inflammatory drugs at castration and tail-docking in neonatal piglets. PloS one. 2021; 16(11):e0254409. doi: 10.1371/journal.pone.0254409. [PMID: 34847143]
  • Emma Nixon, Travis P Mays, Patricia A Routh, James L Yeatts, Virginia R Fajt, Thomas Hairgrove, Ronald E Baynes. Plasma, urine and tissue concentrations of Flunixin and Meloxicam in Pigs. BMC veterinary research. 2020 Sep; 16(1):340. doi: 10.1186/s12917-020-02556-4. [PMID: 32938437]
  • Amir Saeed Samimi, Kamyab Samimi, Marzieh Karimiafshar, Javad Tajik. Comparative Anti-inflammatory Effects of Insulin and Flunixin on Acute-Phase Responses and Cardiovascular Biomarkers During Inflammatory Phase in Miniature Donkeys. Journal of equine veterinary science. 2019 10; 81(?):102788. doi: 10.1016/j.jevs.2019.102788. [PMID: 31668307]
  • Emily J Reppert, Michael D Kleinhenz, Shawnee R Montgomery, Jared Heiman, Amanda Sura, Heather N Bornheim, Geraldine Magnin, Pritam K Sidhu, Yuntao Zhang, Hyun Joo, Johann F Coetzee. Pharmacokinetics and pharmacodynamics of intravenous and transdermal flunixin meglumine in alpacas. Journal of veterinary pharmacology and therapeutics. 2019 Sep; 42(5):572-579. doi: 10.1111/jvp.12800. [PMID: 31353535]
  • Tim Morris, Stuart W Paine, Paul Zahra, Eric Li, Sally Colgan, Steven Karamatic. Plasma and urine pharmacokinetics of intravenously administered flunixin in greyhound dogs. Journal of veterinary pharmacology and therapeutics. 2019 Sep; 42(5):505-510. doi: 10.1111/jvp.12775. [PMID: 31090076]
  • Laura E Burns, David J Borts. Rapid untargeted screening for drug residues in animal tissues with liquid microjunction surface sampling probe mass spectrometry. Analytica chimica acta. 2019 Jul; 1063(?):75-81. doi: 10.1016/j.aca.2019.01.029. [PMID: 30967188]
  • Mary C Cramer, Monique D Pairis-Garcia, Andrew S Bowman, Steven J Moeller, Yuntao Zhang, Pritam K Sidhu, Geraldine Magnin, Johann F Coetzee. Pharmacokinetics of transdermal flunixin in sows. Journal of veterinary pharmacology and therapeutics. 2019 Jul; 42(4):492-495. doi: 10.1111/jvp.12772. [PMID: 31197844]
  • Dafne Garcia-Mateos, Alba Maria Garcia-Lino, Indira Alvarez-Fernandez, Esther Blanco-Paniagua, Alvaro de la Fuente, Ana Isabel Alvarez, Gracia Merino. Role of ABCG2 in Secretion into Milk of the Anti-Inflammatory Flunixin and Its Main Metabolite: In Vitro-In Vivo Correlation in Mice and Cows. Drug metabolism and disposition: the biological fate of chemicals. 2019 05; 47(5):516-524. doi: 10.1124/dmd.118.085506. [PMID: 30858238]
  • Claudia Eleni, Bruno Neri, Luigi Giannetti, Goffredo Grifoni, Roberta Meoli, Fiorentino Stravino, Klaus Gunther Friedrich, Francesco Scholl, Pilar Di Cerbo, Antonio Battisti. Death of captive-bred vultures caused by flunixin poisoning in Italy. Environmental toxicology and pharmacology. 2019 May; 68(?):91-93. doi: 10.1016/j.etap.2019.03.011. [PMID: 30878718]
  • D A Mzyk, C M Bublitz, H Sylvester, K A E Mullen, G D Hobgood, R E Baynes, D M Foster. Short communication: Use of an ultrafiltration device in gland cistern for continuous sampling of healthy and mastitic quarters of lactating cattle for pharmacokinetic modeling. Journal of dairy science. 2018 Nov; 101(11):10414-10420. doi: 10.3168/jds.2018-14849. [PMID: 30197136]
  • Lindsey W Kissell, Patrick D Brinson, Ronette Gehring, Lisa A Tell, Scott E Wetzlich, Ronald E Baynes, Jim E Riviere, Geof W Smith. Pharmacokinetics and tissue elimination of flunixin in veal calves. American journal of veterinary research. 2016 Jun; 77(6):634-40. doi: 10.2460/ajvr.77.6.634. [PMID: 27227502]
  • Weilin L Shelver, David J Smith, Lisa A Tell, Ronald E Baynes, J W Schroeder, Jim E Riviere. Screening and Confirmatory Analyses of Flunixin in Tissues and Bodily Fluids after Intravenous or Intramuscular Administration to Cull Dairy Cows with or without Lipopolysaccharide Challenge. Journal of agricultural and food chemistry. 2016 Jan; 64(1):336-45. doi: 10.1021/acs.jafc.5b04793. [PMID: 26695354]
  • D Marini, J Pippia, I G Colditz, G Hinch, J C Petherick, C Lee. Randomised trial of the bioavailability and efficacy of orally administered flunixin, carprofen and ketoprofen in a pain model in sheep. Australian veterinary journal. 2015 Aug; 93(8):265-70. doi: 10.1111/avj.12351. [PMID: 26220318]
  • D R Paull, A H Small, C Lee, L Labeur, I G Colditz. Effect of local infusion of NSAID analgesics administered alone or in combination on the pain associated with band castration in calves. Australian veterinary journal. 2015 Aug; 93(8):271-7. doi: 10.1111/avj.12348. [PMID: 26220319]
  • Irene Zorrilla, Rosa Martinez, Mark A Taggart, Ngaio Richards. Suspected flunixin poisoning of a wild Eurasian Griffon Vulture from Spain. Conservation biology : the journal of the Society for Conservation Biology. 2015 Apr; 29(2):587-92. doi: 10.1111/cobi.12417. [PMID: 25303011]
  • Boobalan Gopu, Rasakatla Dileep, Matukumalli Usha Rani, C S V Satish Kumar, Matham Vijay Kumar, Alla Gopala Reddy. Protective Role of Curcumin and Flunixin Against Acetic Acid-Induced Inflammatory Bowel Disease via Modulating Inflammatory Mediators and Cytokine Profile in Rats. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. 2015; 34(4):309-20. doi: 10.1615/jenvironpatholtoxicoloncol.2015013049. [PMID: 26756424]
  • Tamsyn Fourie, Duncan Cromarty, Neil Duncan, Kerri Wolter, Vinny Naidoo. The Safety and Pharmacokinetics of Carprofen, Flunixin and Phenylbutazone in the Cape Vulture (Gyps coprotheres) following Oral Exposure. PloS one. 2015; 10(10):e0141419. doi: 10.1371/journal.pone.0141419. [PMID: 26512724]
  • Lindsey W Kissell, Teresa L Leavens, Ronald E Baynes, Jim E Riviere, Geof W Smith. Comparison of pharmacokinetics and milk elimination of flunixin in healthy cows and cows with mastitis. Journal of the American Veterinary Medical Association. 2015 Jan; 246(1):118-25. doi: 10.2460/javma.246.1.118. [PMID: 25517334]
  • Shuna A Jones, Robert S Salter, Tim Goldsmith, Julio Quintana, Paul Rapnicki, Karen Shuck, Jim E Wells, Marilyn J Schneider, Dee Griffin. Development and model testing of antemortem screening methodology to predict required drug withholds in heifers. Journal of food protection. 2014 Feb; 77(2):292-8. doi: 10.4315/0362-028x.jfp-13-267. [PMID: 24490924]
  • Teresa L Leavens, Lisa A Tell, Lindsey W Kissell, Geoffrey W Smith, David J Smith, Sarah A Wagner, Weilin L Shelver, Huali Wu, Ronald E Baynes, Jim E Riviere. Development of a physiologically based pharmacokinetic model for flunixin in cattle (Bos taurus). Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2014; 31(9):1506-21. doi: 10.1080/19440049.2014.938363. [PMID: 25082521]
  • H D Glynn, J F Coetzee, L N Edwards-Callaway, J C Dockweiler, K A Allen, B Lubbers, M Jones, E Fraccaro, L L Bergamasco, B KuKanich. The pharmacokinetics and effects of meloxicam, gabapentin, and flunixin in postweaning dairy calves following dehorning with local anesthesia. Journal of veterinary pharmacology and therapeutics. 2013 Dec; 36(6):550-61. doi: 10.1111/jvp.12042. [PMID: 23473342]
  • Ai-Ling Zhu, Tao Peng, Liang Liu, Xi Xia, Ting Hu, Xiao-Qi Tao, Kai Wen, Lin-Li Cheng, Jian-Cheng Li, Shuang-Yang Ding, Xing-Yuan Cao, Hai-Yang Jiang. Ultra-performance liquid chromatography-tandem mass spectrometry determination and depletion profile of flunixin residues in tissues after single oral administration in rabbits. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2013 Sep; 934(?):8-15. doi: 10.1016/j.jchromb.2013.07.002. [PMID: 23891913]
  • E Fraccaro, J F Coetzee, R Odore, L N Edwards-Callaway, B Kukanich, P Badino, L Bertolotti, H Glynn, J Dockweiler, K Allen, L Bergamasco. A study to compare circulating flunixin, meloxicam and gabapentin concentrations with prostaglandin E₂ levels in calves undergoing dehorning. Research in veterinary science. 2013 Aug; 95(1):204-11. doi: 10.1016/j.rvsc.2013.01.018. [PMID: 23434065]
  • H Wu, R E Baynes, T Leavens, L A Tell, J E Riviere. Use of population pharmacokinetic modeling and Monte Carlo simulation to capture individual animal variability in the prediction of flunixin withdrawal times in cattle. Journal of veterinary pharmacology and therapeutics. 2013 Jun; 36(3):248-57. doi: 10.1111/j.1365-2885.2012.01420.x. [PMID: 22712521]
  • Weilin L Shelver, Lisa A Tell, Sarah Wagner, Scott E Wetzlich, Ronald E Baynes, Jim E Riviere, David J Smith. Comparison of ELISA and LC-MS/MS for the measurement of flunixin plasma concentrations in beef cattle after intravenous and subcutaneous administration. Journal of agricultural and food chemistry. 2013 Mar; 61(11):2679-86. doi: 10.1021/jf304773p. [PMID: 23470029]
  • L W Kissell, G W Smith, T L Leavens, R E Baynes, H Wu, J E Riviere. Plasma pharmacokinetics and milk residues of flunixin and 5-hydroxy flunixin following different routes of administration in dairy cattle. Journal of dairy science. 2012 Dec; 95(12):7151-7. doi: 10.3168/jds.2012-5754. [PMID: 23040013]
  • David R Paull, Alison H Small, Caroline Lee, Pierre Palladin, Ian G Colditz. Evaluating a novel analgesic strategy for ring castration of ram lambs. Veterinary anaesthesia and analgesia. 2012 Sep; 39(5):539-49. doi: 10.1111/j.1467-2995.2012.00716.x. [PMID: 22524300]
  • Gerald Reiner, Frauke Schollasch, Sonja Hillen, Hermann Willems, Marion Piechotta, Klaus Failing. Effects of meloxicam and flunixin on pain, stress and discomfort in male piglets during and after surgical castration. Berliner und Munchener tierarztliche Wochenschrift. 2012 Jul; 125(7-8):305-14. doi: . [PMID: 22919924]
  • M A Popot, P Garcia, Y Bonnaire. Doping control in horses: housing conditions and oral recycling of flunixin by ingestion of contaminated straw. Journal of veterinary pharmacology and therapeutics. 2011 Dec; 34(6):612-4. doi: 10.1111/j.1365-2885.2011.01276.x. [PMID: 21995754]
  • P Kallings, S G B Persson, B Essén-Gustavsson. Effects of flunixin on cardiorespiratory, plasma lactate and stride length responses to intense treadmill exercise in Standardbred trotters. Equine veterinary journal. Supplement. 2010 Nov; ?(38):618-23. doi: 10.1111/j.2042-3306.2010.00298.x. [PMID: 21059070]
  • A A Mozaffari, A Derakhshanfar, A Alinejad, M Morovati. A comparative study on the adverse effects of flunixin, ketoprofen and phenylbutazone in miniature donkeys: haematological, biochemical and pathological findings. New Zealand veterinary journal. 2010 Oct; 58(5):224-8. doi: 10.1080/00480169.2010.69295. [PMID: 20927172]
  • Dianne Little, S Aubrey Brown, Nigel B Campbell, Adam J Moeser, Jennifer L Davis, Anthony T Blikslager. Effects of the cyclooxygenase inhibitor meloxicam on recovery of ischemia-injured equine jejunum. American journal of veterinary research. 2007 Jun; 68(6):614-24. doi: 10.2460/ajvr.68.6.614. [PMID: 17542694]
  • D R Paull, C Lee, I G Colditz, S J Atkinson, A D Fisher. The effect of a topical anaesthetic formulation, systemic flunixin and carprofen, singly or in combination, on cortisol and behavioural responses of Merino lambs to mulesing. Australian veterinary journal. 2007 Mar; 85(3):98-106. doi: 10.1111/j.1751-0813.2007.00115.x. [PMID: 17359309]
  • Yi Luo, Jeffrey A Rudy, Cornelius E Uboh, Lawrence R Soma, Fuyu Guan, James M Enright, Deborah S Tsang. Quantification and confirmation of flunixin in equine plasma by liquid chromatography-quadrupole time-of-flight tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 Mar; 801(2):173-84. doi: 10.1016/j.jchromb.2003.11.002. [PMID: 14751785]
  • Pamela L Boner, Dave D W Liu, William F Feely, Robert A Robinson, Jinn Wu. Determination of flunixin in edible bovine tissues using liquid chromatography coupled with tandem mass spectrometry. Journal of agricultural and food chemistry. 2003 Dec; 51(26):7555-9. doi: 10.1021/jf034880n. [PMID: 14664506]
  • Thiruma V Arumugam, Naomi Arnold, Lavinia M Proctor, Michelle Newman, Robert C Reid, Karl A Hansford, David P Fairlie, Ian A Shiels, Stephen M Taylor. Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. British journal of pharmacology. 2003 Sep; 140(1):71-80. doi: 10.1038/sj.bjp.0705402. [PMID: 12967936]
  • K Baert, P De Backer. Comparative pharmacokinetics of three non-steroidal anti-inflammatory drugs in five bird species. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2003 Jan; 134(1):25-33. doi: 10.1016/s1532-0456(02)00184-9. [PMID: 12524015]
  • K Königsson, K Törneke, I V Engeland, K Odensvik, H Kindahl. Pharmacokinetics and pharmacodynamic effects of flunixin after intravenous, intramuscular and oral administration to dairy goats. Acta veterinaria Scandinavica. 2003; 44(3-4):153-9. doi: 10.1186/1751-0147-44-153. [PMID: 15074628]
  • K Baert, P De Backer. Disposition of sodium salicylate, flunixin and meloxicam after intravenous administration in broiler chickens. Journal of veterinary pharmacology and therapeutics. 2002 Dec; 25(6):449-53. doi: 10.1046/j.1365-2885.2002.00441.x. [PMID: 12485350]
  • K L Machin, L A Tellier, S Lair, A Livingston. Pharmacodynamics of flunixin and ketoprofen in mallard ducks (Anas platyrhynchos). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2001 Jun; 32(2):222-9. doi: 10.1638/1042-7260(2001)032[0222:pofaki]2.0.co;2. [PMID: 12790425]
  • J L Baker, M Aleman, J Madigan. Intermittent hypoglycemia in a horse with anaplastic carcinoma of the kidney. Journal of the American Veterinary Medical Association. 2001 Jan; 218(2):235-7. doi: 10.2460/javma.2001.218.235. [PMID: 11195830]
  • R A Sams, D F Gerken, S M Ashcraft. Detection and identification of flunixin after multiple intravenous and intramuscular doses to horses. Journal of analytical toxicology. 1999 Sep; 23(5):372-9. doi: 10.1093/jat/23.5.372. [PMID: 10488926]
  • H A el-Banna. Pharmacokinetic interactions between flunixin and sulphadimidine in horses. DTW. Deutsche tierarztliche Wochenschrift. 1999 Sep; 106(9):400-3. doi: NULL. [PMID: 10547934]
  • P Kallings, C Johnston, S Drevemo. Effects of flunixin on movement and performance of standardbred trotters on the track. Equine veterinary journal. Supplement. 1999 Jul; ?(30):270-3. doi: 10.1111/j.2042-3306.1999.tb05233.x. [PMID: 10659267]
  • I A Wasfi, N S Boni, A Abdel Hadi, M Elghazali, O Zorob, N A Alkatheeri, I M Barezaiq. Pharmacokinetics, metabolism and urinary detection time of flunixin after intravenous administration in camels. Journal of veterinary pharmacology and therapeutics. 1998 Jun; 21(3):203-8. doi: 10.1046/j.1365-2885.1998.00122.x. [PMID: 9673961]
  • I A Wasfi, A A Hadi, N A Alkatheeri, I M Barezaiq, M ElGhazali, N S Boni, O Zorob. Identification of a flunixin metabolite in camel by gas chromatography-mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications. 1998 May; 709(2):209-15. doi: 10.1016/s0378-4347(98)00057-7. [PMID: 9657217]
  • T C Brady, A J Kind, W H Hyde, M Favrow, D W Hill. Isolation, purification, and structural characterization of flunixin glucuronide in the urine of greyhound dogs. Drug metabolism and disposition: the biological fate of chemicals. 1998 Apr; 26(4):294-8. doi: NULL. [PMID: 9531514]
  • T C Brady, T J Yang, W G Hyde, A J Kind, D W Hill. Detection of flunixin in greyhound urine by a kinetic enzyme-linked immunosorbent assay. Journal of analytical toxicology. 1997 May; 21(3):190-6. doi: 10.1093/jat/21.3.190. [PMID: 9171201]
  • X Gu, M Meleka-Boules, C L Chen, D M Ceska, D M Tiffany. Determination of flunixin in equine urine and serum by capillary electrophoresis. Journal of chromatography. B, Biomedical sciences and applications. 1997 Apr; 692(1):187-98. doi: 10.1016/s0378-4347(96)00393-3. [PMID: 9187399]
  • K A Mathews, D M Paley, R A Foster, A E Valliant, S S Young. A comparison of ketorolac with flunixin, butorphanol, and oxymorphone in controlling postoperative pain in dogs. The Canadian veterinary journal = La revue veterinaire canadienne. 1996 Sep; 37(9):557-67. doi: . [PMID: 8877043]
  • R Scherkl, A Hashem, H H Frey. [The tissue cage in dogs--a pharmacologic model for the representation of plasma and tissue kinetics]. DTW. Deutsche tierarztliche Wochenschrift. 1996 May; 103(5):174-7. doi: NULL. [PMID: 8964239]
  • M F Landoni, F M Cunningham, P Lees. Comparative pharmacodynamics of flunixin, ketoprofen and tolfenamic acid in calves. The Veterinary record. 1995 Oct; 137(17):428-31. doi: 10.1136/vr.137.17.428. [PMID: 8560701]
  • M F Landoni, P Lees. Comparison of the anti-inflammatory actions of flunixin and ketoprofen in horses applying PK/PD modelling. Equine veterinary journal. 1995 Jul; 27(4):247-56. doi: 10.1111/j.2042-3306.1995.tb03073.x. [PMID: 8536660]
  • M F Landoni, F M Cunningham, P Lees. Determination of pharmacokinetics and pharmacodynamics of flunixin in calves by use of pharmacokinetic/pharmacodynamic modeling. American journal of veterinary research. 1995 Jun; 56(6):786-94. doi: . [PMID: 7653889]
  • S M Stanley, N A Owens, J P Rodgers. Detection of flunixin in equine urine using high-performance liquid chromatography with particle beam and atmospheric pressure ionization mass spectrometry after solid-phase extraction. Journal of chromatography. B, Biomedical applications. 1995 May; 667(1):95-103. doi: 10.1016/0378-4347(94)00603-3. [PMID: 7663690]
  • K Odensvik, I M Johansson. High-performance liquid chromatography method for determination of flunixin in bovine plasma and pharmacokinetics after single and repeated doses of the drug. American journal of veterinary research. 1995 Apr; 56(4):489-95. doi: NULL. [PMID: 7785828]
  • S D Semrad. Comparative efficacy of flunixin, ketoprofen, and ketorolac for treating endotoxemic neonatal calves. American journal of veterinary research. 1993 Sep; 54(9):1511-6. doi: . [PMID: 8239142]
  • P Dobromylskyj. Intraoperative use of flunixin meglumine. The Veterinary record. 1992 Nov; 131(22):520. doi: 10.1136/vr.131.22.520. [PMID: 1300683]
  • P Smitherman. Intra-operative use of flunixin meglumine. The Veterinary record. 1992 Nov; 131(20):471. doi: 10.1136/vr.131.20.471-b. [PMID: 1466125]
  • C Elwood, A Boswood, K Simpson, S Carmichael. Renal failure after flunixin meglumine administration. The Veterinary record. 1992 Jun; 130(26):582-3. doi: 10.1136/vr.130.26.582-a. [PMID: 1308097]
  • J C Welsh, P Lees, G Stodulski, H Cambridge, A P Foster. Influence of feeding schedule on the absorption of orally administered flunixin in the horse. Equine veterinary journal. Supplement. 1992 Feb; ?(11):62-5. doi: 10.1111/j.2042-3306.1992.tb04776.x. [PMID: 9109964]
  • A K Singh, Y Jang, U Mishra, K Granley. Simultaneous analysis of flunixin, naproxen, ethacrynic acid, indomethacin, phenylbutazone, mefenamic acid and thiosalicylic acid in plasma and urine by high-performance liquid chromatography and gas chromatography-mass spectrometry. Journal of chromatography. 1991 Aug; 568(2):351-61. doi: 10.1016/0378-4347(91)80173-a. [PMID: 1783641]
  • M A O'Brien, W P Duffus. The effects of dexamethasone, betamethasone, flunixin and phenylbutazone on bovine natural-killer-cell cytotoxicity. Journal of veterinary pharmacology and therapeutics. 1990 Sep; 13(3):292-7. doi: 10.1111/j.1365-2885.1990.tb00779.x. [PMID: 2231870]
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  • A D Pemberton, J S Slater, E M Milne. An improved TLC method for the detection of flunixin in equine serum. Research in veterinary science. 1989 Nov; 47(3):406-7. doi: 10.1016/s0034-5288(18)31273-6. [PMID: 2595101]
  • J Luthman, H Kindahl, S O Jacobsson. The influence of flunixin on the response to Salmonella typhimurium endotoxin in calves. Acta veterinaria Scandinavica. 1989; 30(3):295-300. doi: 10.1186/bf03548034. [PMID: 2698058]
  • M Johansson, E L Anlér. Gas chromatographic analysis of flunixin in equine urine after extractive methylation. Journal of chromatography. 1988 May; 427(1):55-66. doi: 10.1016/0378-4347(88)80104-x. [PMID: 3261730]
  • P Jaussaud, D Courtot, J L Guyot, J Paris. Identification of a flunixin metabolite in the horse by gas chromatography-mass spectrometry. Journal of chromatography. 1987 Dec; 423(?):123-30. doi: 10.1016/0378-4347(87)80334-1. [PMID: 3502127]
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