Torsemide (BioDeep_00000397826)
natural product
代谢物信息卡片
Torsemide (Demadex)
化学式: C16H20N4O3S (348.12560500000006)
中文名称: 托拉塞米
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(=C(C=CN=C1)NC2=CC(=CC=C2)C)S(NC(NC(C)C)=O)(=O)=O
InChI: InChI=1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)
描述信息
D045283 - Natriuretic Agents > D004232 - Diuretics > D049994 - Sodium Potassium Chloride Symporter Inhibitors
C - Cardiovascular system > C03 - Diuretics > C03C - High-ceiling diuretics > C03CA - Sulfonamides, plain
C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49184 - Loop Diuretic
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents
D049990 - Membrane Transport Modulators
CONFIDENCE standard compound; INTERNAL_ID 2365
CONFIDENCE standard compound; INTERNAL_ID 8192
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3145
同义名列表
3 个代谢物同义名
数据库引用编号
32 个数据库交叉引用编号
- ChEBI: CHEBI:9637
- KEGGdrug: D00382
- PubChem: 41781
- DrugBank: DB00214
- ChEMBL: CHEMBL1148
- MeSH: Torsemide
- CAS: 56211-40-6
- MoNA: AU236560
- MoNA: AU236559
- MoNA: AU236558
- MoNA: AU236557
- MoNA: AU236506
- MoNA: AU236505
- MoNA: AU236504
- MoNA: AU236503
- MoNA: AU236502
- MoNA: AU236501
- MoNA: SM819252
- MoNA: SM819202
- MoNA: CCMSLIB00000078242
- MoNA: EQ314556
- MoNA: EQ314555
- MoNA: EQ314554
- MoNA: EQ314553
- MoNA: EQ314552
- MoNA: EQ314551
- MoNA: EQ314506
- MoNA: EQ314505
- MoNA: EQ314504
- MoNA: EQ314503
- MoNA: EQ314502
- MoNA: EQ314501
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lauren B Cooper, Scott Bruce, Mitchell Psotka, Robert Mentz, Rachel Bell, Stephen L Seliger, Christopher O'Connor, Christopher deFilippi. Proteomic differences among patients with heart failure taking furosemide or torsemide.
Clinical cardiology.
2022 Mar; 45(3):265-272. doi:
10.1002/clc.23733. [PMID: 35014074] - Evelyne Coussanes, Emilie Guillot, Reynald Magnier, Anne Geneteau, Jonathan Elliott. Safety of torasemide in healthy adult dogs administered daily for 26 weeks.
Journal of veterinary pharmacology and therapeutics.
2022 Mar; 45(2):153-166. doi:
10.1111/jvp.13030. [PMID: 34791658] - Philip Hampel, Kerstin Römermann, Björn Gailus, Marie Johne, Birthe Gericke, Edith Kaczmarek, Wolfgang Löscher. Effects of the NKCC1 inhibitors bumetanide, azosemide, and torasemide alone or in combination with phenobarbital on seizure threshold in epileptic and nonepileptic mice.
Neuropharmacology.
2021 03; 185(?):108449. doi:
10.1016/j.neuropharm.2021.108449. [PMID: 33450274] - Philip Hampel, Kerstin Römermann, Martina Gramer, Wolfgang Löscher. The search for brain-permeant NKCC1 inhibitors for the treatment of seizures: Pharmacokinetic-pharmacodynamic modelling of NKCC1 inhibition by azosemide, torasemide, and bumetanide in mouse brain.
Epilepsy & behavior : E&B.
2021 01; 114(Pt A):107616. doi:
10.1016/j.yebeh.2020.107616. [PMID: 33279441] - Jingyi Hu, Qianli Wan, Yue Zhang, Jun Zhou, Miaomiao Li, Li Jiang, Fang Yuan. Efficacy and safety of early ultrafiltration in patients with acute decompensated heart failure with volume overload: a prospective, randomized, controlled clinical trial.
BMC cardiovascular disorders.
2020 10; 20(1):447. doi:
10.1186/s12872-020-01733-5. [PMID: 33054727] - Sascha Lege, Julian Sorwat, Jorge Eduardo Yanez Heras, Christian Zwiener. Abiotic and biotic transformation of torasemide - Occurrence of degradation products in the aquatic environment.
Water research.
2020 Jun; 177(?):115753. doi:
10.1016/j.watres.2020.115753. [PMID: 32302808] - Nourin Ali Sherif, Mostafa Ebraheem Morra, Le Van Thanh, Ghadeer Gamal Elsayed, Aya Hesham Elkady, Abdelrahman Elshafay, Nguyen Dang Kien, Ahmed Al-Habbaa, Le Huu Nhat Minh, Mai Nhu Y, Thai Le Ba Nghia, Abdelrhman Tarek Mohammed, Peter Samuel Eid, Tarek Turk, Kenji Hirayama, Nguyen Tien Huy. Torasemide versus furosemide in treatment of heart failure: A systematic review and meta-analysis of randomized controlled trials.
Journal of evaluation in clinical practice.
2020 Jun; 26(3):842-851. doi:
10.1111/jep.13261. [PMID: 31436024] - B M Potter, M K Ames, A Hess, M Poglitsch. Comparison between the effects of torsemide and furosemide on the renin-angiotensin-aldosterone system of normal dogs.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology.
2019 Dec; 26(?):51-62. doi:
10.1016/j.jvc.2019.11.003. [PMID: 31809955] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Dorota Watrobska-Swietlikowska, Magdalena Pietka, Stanislaw Klek. Evaluation of Y-site compatibility of home total parenteral nutrition and intravenous loop diuretics.
Medicine.
2019 May; 98(21):e15747. doi:
10.1097/md.0000000000015747. [PMID: 31124957] - Luise Henneberger, Marie Mühlenbrink, Fabian C Fischer, Beate I Escher. C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
Chemical research in toxicology.
2019 01; 32(1):168-178. doi:
10.1021/acs.chemrestox.8b00249. [PMID: 30585484] - Gustavo F Agne, Seung Woo Jung, Anne A Wooldridge, Susan H Duran, William Ravis, Ramiro Toribio. Pharmacokinetic and pharmacodynamic properties of orally administered torsemide in healthy horses.
Journal of veterinary internal medicine.
2018 Jul; 32(4):1428-1435. doi:
10.1111/jvim.15213. [PMID: 29770976] - Tobias Daniel Trippel, Sophie Van Linthout, Dirk Westermann, Ruhdja Lindhorst, Anja Sandek, Stefanie Ernst, Anna Bobenko, Mario Kasner, Frank Spillmann, Arantxa González, Begoña López, Susana Ravassa, Burkert Pieske, Walter J Paulus, Javier Díez, Frank Edelmann, Carsten Tschöpe. Investigating a biomarker-driven approach to target collagen turnover in diabetic heart failure with preserved ejection fraction patients. Effect of torasemide versus furosemide on serum C-terminal propeptide of procollagen type I (DROP-PIP trial).
European journal of heart failure.
2018 03; 20(3):460-470. doi:
10.1002/ejhf.960. [PMID: 28891228] - Salim Shah, Bertram Pitt, D Craig Brater, Peter U Feig, Wen Shen, Fatima S Khwaja, Christopher S Wilcox. Sodium and Fluid Excretion With Torsemide in Healthy Subjects is Limited by the Short Duration of Diuretic Action.
Journal of the American Heart Association.
2017 Oct; 6(10):. doi:
10.1161/jaha.117.006135. [PMID: 28982672] - Patrick Slattery, Stefanie Frölich, Itamar Goren, Rolf M Nüsing. Salt supplementation ameliorates developmental kidney defects in COX-2-/- mice.
American journal of physiology. Renal physiology.
2017 06; 312(6):F1044-F1055. doi:
10.1152/ajprenal.00565.2016. [PMID: 28274925] - A Paulin, M Schneider, F Dron, F Woehrlé. A pharmacokinetic/pharmacodynamic model capturing the time course of torasemide-induced diuresis in the dog.
Journal of veterinary pharmacology and therapeutics.
2016 Dec; 39(6):547-559. doi:
10.1111/jvp.12316. [PMID: 27230410] - Tim Heise, Jens Jordan, Christoph Wanner, Martina Heer, Sreeraj Macha, Michaela Mattheus, Søren S Lund, Hans J Woerle, Uli C Broedl. Acute Pharmacodynamic Effects of Empagliflozin With and Without Diuretic Agents in Patients With Type 2 Diabetes Mellitus.
Clinical therapeutics.
2016 Oct; 38(10):2248-2264.e5. doi:
10.1016/j.clinthera.2016.08.008. [PMID: 27666126] - Jonathan Buggey, Robert J Mentz, Bertram Pitt, Eric L Eisenstein, Kevin J Anstrom, Eric J Velazquez, Christopher M O'Connor. A reappraisal of loop diuretic choice in heart failure patients.
American heart journal.
2015 Mar; 169(3):323-33. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2015 Feb; 43(2):235-47. doi:
10.1124/dmd.114.059105. [PMID: 25414411] - Andrew Rowland, David Hallifax, Matthew R Nussio, Joseph G Shapter, Peter I Mackenzie, J Brian Houston, Kathleen M Knights, John O Miners. Characterization of the comparative drug binding to intra- (liver fatty acid binding protein) and extra- (human serum albumin) cellular proteins.
Xenobiotica; the fate of foreign compounds in biological systems.
2015; 45(10):847-57. doi:
10.3109/00498254.2015.1021403. [PMID: 25801059] - Venkatesan Subramanian, Kannappan Nagappan, Sai Sandeep Mannemala. Optimization and Validation of a Sensitive Method for HPLC-PDA Simultaneous Determination of Torasemide and Spironolactone in Human Plasma using Central Composite Design.
Acta chimica Slovenica.
2015; 62(3):633-41. doi:
10.17344/acsi.2014.1262. [PMID: 26454598] - Nawar Dalila, Jürgen Brockmöller, Mladen Vassilev Tzvetkov, Markus Schirmer, Martin Haubrock, Stefan Viktor Vormfelde. Impact of mineralocorticoid receptor polymorphisms on urinary electrolyte excretion with and without diuretic drugs.
Pharmacogenomics.
2015 Jan; 16(2):115-27. doi:
10.2217/pgs.14.163. [PMID: 25616098] - Maria Rosa Ballester, Eulàlia Roig, Ignasi Gich, Montse Puntes, Joaquín Delgadillo, Benjamín Santos, Rosa Maria Antonijoan. Randomized, open-label, blinded-endpoint, crossover, single-dose study to compare the pharmacodynamics of torasemide-PR 10 mg, torasemide-IR 10 mg, and furosemide-IR 40 mg, in patients with chronic heart failure.
Drug design, development and therapy.
2015; 9(?):4291-302. doi:
10.2147/dddt.s86300. [PMID: 26273191] - Somasundaram Arumugam, Remya Sreedhar, Shizuka Miyashita, Vengadeshprabhu Karuppagounder, Rajarajan A Thandavarayan, Vijayasree V Giridharan, Vigneshwaran Pitchaimani, Rejina Afrin, Meilei Harima, Kenji Suzuki, Kenichi Watanabe. Comparative evaluation of torasemide and furosemide on rats with streptozotocin-induced diabetic nephropathy.
Experimental and molecular pathology.
2014 Aug; 97(1):137-43. doi:
10.1016/j.yexmp.2014.06.007. [PMID: 24960275] - G P Arutiunov, D O Dragunov, A V Sokolova. [Effect of loop diuretics with different elimination half-lives on natriuresis changes and indicators characterizing the state of renal tubulointerstitial tissue].
Terapevticheskii arkhiv.
2014; 86(6):38-44. doi:
NULL. [PMID: 25095654] - Zhiping Cui, Shaopu Liu, Zhongfang Liu, Yuanfang Li, Xiaoli Hu, Jing Tian. Determination of torasemide by fluorescence quenching method with some dihalogenated fluorescein dyes as probes.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2013 Oct; 114(?):547-52. doi:
10.1016/j.saa.2013.05.080. [PMID: 23792294] - Han Oll Kim, Kyung Eun Lee, Hee Yoon Park, Na Ra Lee, Byeou Ree Oh, Byung Chul Chang, Hye Sun Gwak. Effects of torsemide on pharmacodynamics and pharmacokinetics of warfarin in humans and rats.
The Journal of pharmacy and pharmacology.
2013 Aug; 65(8):1195-203. doi:
10.1111/jphp.12084. [PMID: 23837587] - X-M Li, D-X Jin, H-L Cong. Could torasemide be a prophylactic agent of contrast induced acute kidney injury? A review about this field.
European review for medical and pharmacological sciences.
2013 Jul; 17(14):1845-9. doi:
NULL. [PMID: 23877845] - F L Dini, S Ghio, C Klersy, A Rossi, A Simioniuc, L Scelsi, F T Genta, M Cicoira, L Tavazzi, P L Temporelli. Effects on survival of loop diuretic dosing in ambulatory patients with chronic heart failure using a propensity score analysis.
International journal of clinical practice.
2013 Jul; 67(7):656-64. doi:
10.1111/ijcp.12144. [PMID: 23758444] - Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Dec; 40(12):2332-41. doi:
10.1124/dmd.112.047068. [PMID: 22961681] - R De Vecchis, C Ariano, C Esposito, A Giasi, C Cioppa, S Cantatrione. In right or biventricular chronic heart failure addition of thiazides to loop diuretics to achieve a sequential blockade of the nephron is associated with increased risk of dilutional hyponatremia: results of a case-control study.
Minerva cardioangiologica.
2012 Oct; 60(5):517-29. doi:
NULL. [PMID: 23018431] - Gordon D Peddle, Gretchen E Singletary, Caryn A Reynolds, Dennis J Trafny, Maggie C Machen, Mark A Oyama. Effect of torsemide and furosemide on clinical, laboratory, radiographic and quality of life variables in dogs with heart failure secondary to mitral valve disease.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology.
2012 Mar; 14(1):253-9. doi:
10.1016/j.jvc.2012.01.003. [PMID: 22364690] - R De Vecchis, A Ciccarelli, C Ariano, C Cioppa, A Giasi, A Pucciarelli, S Cantatrione. In chronic heart failure with marked fluid retention, the i.v. high doses of loop diuretic are a predictor of aggravated renal dysfunction, especially in the set of heart failure with normal or only mildly impaired left ventricular systolic function.
Minerva cardioangiologica.
2011 Dec; 59(6):543-54. doi:
NULL. [PMID: 21330961] - NULL. Effects of prolonged-release torasemide versus furosemide on myocardial fibrosis in hypertensive patients with chronic heart failure: a randomized, blinded-end point, active-controlled study.
Clinical therapeutics.
2011 Sep; 33(9):1204-1213.e3. doi:
10.1016/j.clinthera.2011.08.006. [PMID: 21906812] - Cuixia Li, Xiaoli Hu, Shaopu Liu, Zhongfang Liu. Study on the interaction between torasemide and 12-tungstophosphoric acid by resonance Rayleigh scattering and resonance nonlinear scattering spectra and its analytical applications.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2011 Sep; 79(5):1084-90. doi:
10.1016/j.saa.2011.04.023. [PMID: 21658991] - Z Khawaja, C S Wilcox. Role of the kidneys in resistant hypertension.
International journal of hypertension.
2011 Mar; 2011(?):143471. doi:
10.4061/2011/143471. [PMID: 21461391] - Offie P Soldin, Sarah H Chung, Donald R Mattison. Sex differences in drug disposition.
Journal of biomedicine & biotechnology.
2011; 2011(?):187103. doi:
10.1155/2011/187103. [PMID: 21403873] - S G Kanorskiĭ, V G Tregubov, V M Pokrovskiĭ. [Alternative therapy with ivabradine in patients with functional class III chronic heart failure].
Kardiologiia.
2011; 51(8):39-44. doi:
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PloS one.
2010 Dec; 5(12):e14328. doi:
10.1371/journal.pone.0014328. [PMID: 21179199] - S Reddy, A Bahl, K K Talwar. Congestive heart failure in Indians: how do we improve diagnosis & management?.
The Indian journal of medical research.
2010 Nov; 132(?):549-60. doi:
NULL. [PMID: 21150007] - Dulcenombre Gómez-Garre, Ma Luisa González-Rubio, Paloma Muñoz-Pacheco, Alicia Caro-Vadillo, Paloma Aragoncillo, Arturo Fernández-Cruz. Rosuvastatin added to standard heart failure therapy improves cardiac remodelling in heart failure rats with preserved ejection fraction.
European journal of heart failure.
2010 Sep; 12(9):903-12. doi:
10.1093/eurjhf/hfq101. [PMID: 20601374] - Swagata Tripathy, Suresh Chandra Dash. Etoricoxib-induced life-threatening hyperkalemia and acute kidney dysfunction against the background of telmisartan and a low sodium diet.
International journal of emergency medicine.
2010 Aug; 3(4):443-6. doi:
10.1007/s12245-010-0208-6. [PMID: 21373319] - Robert J MacFadyen, Marie Jennyfer Ng Kam Chuen, Russell C Davis. Loop diuretic therapy in left ventricular systolic dysfunction: has familiarity bred contempt for a critical but potentially nephrotoxic cardio renal therapy?.
European journal of heart failure.
2010 Jul; 12(7):649-52. doi:
10.1093/eurjhf/hfq104. [PMID: 20576834] - Carmen Acuña. [Update: prolonged-release torasemide].
Drugs of today (Barcelona, Spain : 1998).
2010 Jul; 46 Suppl E(?):1-15. doi:
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Renal failure.
2010 Jul; 32(6):673-9. doi:
10.3109/0886022x.2010.486492. [PMID: 20540634] - Sanjay Gupta, Carolyn Waywell, Nandkumar Gandhi, Nigel Clayton, Brian Keevil, Andrew L Clark, Leong L Ng, Nicholas Brooks, Ludwig Neyses. The effects of adding torasemide to standard therapy on peak oxygen consumption, natriuretic peptides, and quality of life in patients with compensated left ventricular systolic dysfunction.
European journal of heart failure.
2010 Jul; 12(7):746-52. doi:
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Journal of chromatography. A.
2010 May; 1217(20):3392-9. doi:
10.1016/j.chroma.2010.03.008. [PMID: 20362295] - E A Tabak'ian, A Iu Zaruba, A N Rogoza, D M Ataullakhanova, V V Kukharchuk. [Determination of brain natriuretic peptide levels and its N-terminal fragment for the evaluation of renal replacement therapies efficiency in patients with decompensated chronic heart failure].
Terapevticheskii arkhiv.
2010; 82(8):24-9. doi:
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The Annals of pharmacotherapy.
2009 Nov; 43(11):1836-47. doi:
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Annals of Saudi medicine.
2009 Sep; 29(5):369-77. doi:
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Journal of medicinal chemistry.
2009 Aug; 52(15):4844-52. doi:
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Expert review of cardiovascular therapy.
2009 Aug; 7(8):897-904. doi:
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Drugs.
2009 Jul; 69(10):1363-72. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2009 Jul; 37(7):1395-403. doi:
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Praxis.
2009 Jun; 98(13):685-90; quiz 691. doi:
10.1024/1661-8157.98.13.685. [PMID: 19551652] - Ken Harada, Hideo Izawa, Takao Nishizawa, Akihiro Hirashiki, Yosuke Murase, Masakazu Kobayashi, Satoshi Isobe, Xian Wu Cheng, Akiko Noda, Kohzo Nagata, Mitsuhiro Yokota, Toyoaki Murohara. Beneficial effects of torasemide on systolic wall stress and sympathetic nervous activity in asymptomatic or mildly symptomatic patients with heart failure: comparison with azosemide.
Journal of cardiovascular pharmacology.
2009 Jun; 53(6):468-73. doi:
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European journal of clinical pharmacology.
2009 May; 65(5):465-72. doi:
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Clinical and experimental pharmacology & physiology.
2009 May; 36(5-6):469-77. doi:
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Journal of medical case reports.
2009 Mar; 3(?):6164. doi:
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Fundamental & clinical pharmacology.
2009 Feb; 23(1):115-25. doi:
10.1111/j.1472-8206.2008.00643.x. [PMID: 19267775] - A A K El-Sheikh, J J M W van den Heuvel, J B Koenderink, F G M Russel. Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4.
British journal of pharmacology.
2008 Dec; 155(7):1066-75. doi:
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Kidney international. Supplement.
2008 Dec; ?(111):S19-23. doi:
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Archives of disease in childhood.
2008 Sep; 93(9):768-71. doi:
10.1136/adc.2007.129239. [PMID: 18337280] - R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Jul; 36(7):1385-405. doi:
10.1124/dmd.108.020479. [PMID: 18426954] - I J Khan, P Loya, M N Saraf. A simplified HPLC method for quantification of torsemide from human plasma and its application to a bioequivalence study.
Indian journal of pharmaceutical sciences.
2008 Jul; 70(4):519-22. doi:
10.4103/0250-474x.44609. [PMID: 20046786] - Mathias Streitz, Michel Noutsias, Rudolf Volkmer, Maria Rohde, Gordon Brestrich, Andrea Block, Katrin Klippert, Katja Kotsch, Bernhard Ay, Michael Hummel, Uwe Kühl, Dirk Lassner, Heinz-Peter Schultheiss, Hans-Dieter Volk, Florian Kern. NS1 specific CD8+ T-cells with effector function and TRBV11 dominance in a patient with parvovirus B19 associated inflammatory cardiomyopathy.
PloS one.
2008 Jun; 3(6):e2361. doi:
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Archives of dermatology.
2008 Jun; 144(6):812-3. doi:
10.1001/archderm.144.6.812. [PMID: 18559783] - Vincent L M Esnault, Edwina A Brown, Eduard Apetrei, Jacques Bagon, Carlos Calvo, Rudolf DeChatel, Hallvard Holdaas, Silvester Krcmery, Zhanna Kobalava. The effects of amlodipine and enalapril on renal function in adults with hypertension and nondiabetic nephropathies: a 3-year, randomized, multicenter, double-blind, placebo-controlled study.
Clinical therapeutics.
2008 Mar; 30(3):482-98. doi:
10.1016/j.clinthera.2008.03.006. [PMID: 18405787] - Pietro Gareri, Pasquale De Fazio, Luca Gallelli, Salvatore De Fazio, Alessandro Davoli, Giuseppe Seminara, Antonino Cotroneo, Giovambattista De Sarro. Venlafaxine-propafenone interaction resulting in hallucinations and psychomotor agitation.
The Annals of pharmacotherapy.
2008 Mar; 42(3):434-8. doi:
10.1345/aph.1k405. [PMID: 18303146] - Punniyakoti T Veeraveedu, Kenichi Watanabe, Meilei Ma, Suresh S Palaniyandi, Ken'ichi Yamaguchi, Kenji Suzuki, Makoto Kodama, Yoshifusa Aizawa. Torasemide, a long-acting loop diuretic, reduces the progression of myocarditis to dilated cardiomyopathy.
European journal of pharmacology.
2008 Feb; 581(1-2):121-31. doi:
10.1016/j.ejphar.2007.11.034. [PMID: 18154949] - R L Mehta, F Cantarovich, A Shaw, E Hoste, P Murray. Pharmacologic approaches for volume excess in acute kidney injury (AKI).
The International journal of artificial organs.
2008 Feb; 31(2):127-44. doi:
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Biochemical pharmacology.
2008 Feb; 75(3):649-59. doi:
10.1016/j.bcp.2007.09.026. [PMID: 18001696] - Vera von Dossow, Claudia Spies, Hannes Schenk, Sabine Schlesinger, Christian von Heymann. Secondary pulmonary hypertension: haemodynamic effects of torasemide versus furosemide.
Clinical drug investigation.
2008; 28(1):17-26. doi:
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Clinical pharmacokinetics.
2008; 47(5):323-32. doi:
10.2165/00003088-200847050-00003. [PMID: 18399713] - Yasutomo Hori, Fumihiko Takusagawa, Hiromi Ikadai, Masami Uechi, Fumio Hoshi, Sei-ichi Higuchi. Effects of oral administration of furosemide and torsemide in healthy dogs.
American journal of veterinary research.
2007 Oct; 68(10):1058-63. doi:
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Clinical pharmacology and therapeutics.
2007 Sep; 82(3):300-9. doi:
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The Veterinary record.
2007 Jun; 160(24):847-8. doi:
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The pharmacogenomics journal.
2007 Jun; 7(3):200-11. doi:
10.1038/sj.tpj.6500410. [PMID: 16969365] - Sean M Bagshaw, Anthony Delaney, Michael Haase, William A Ghali, Rinaldo Bellomo. Loop diuretics in the management of acute renal failure: a systematic review and meta-analysis.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine.
2007 Mar; 9(1):60-8. doi:
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The Annals of pharmacotherapy.
2006 Oct; 40(10):1797-803. doi:
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British journal of clinical pharmacology.
2006 Sep; 62(3):323-35. doi:
10.1111/j.1365-2125.2006.02655.x. [PMID: 16934049] - Shervin Eshaghian, Tamara B Horwich, Gregg C Fonarow. Relation of loop diuretic dose to mortality in advanced heart failure.
The American journal of cardiology.
2006 Jun; 97(12):1759-64. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 Feb; 831(1-2):31-5. doi:
10.1016/j.jchromb.2005.11.013. [PMID: 16344009] - G Splendiani, S Condò. [Diuretic therapy in heart failure].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia.
2006 Jan; 23 Suppl 34(?):S74-6. doi:
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Kardiologiia.
2006; 46(10):75-86. doi:
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Medicina (Kaunas, Lithuania).
2006; 42(8):649-52. doi:
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Biopharmaceutics & drug disposition.
2005 Nov; 26(8):371-8. doi:
10.1002/bdd.467. [PMID: 16094676] - Sang-Woong Han, Ho-Jung Kim, Man S Oh. Comparison of the urine acidification tests of torsemide vs furosemide in healthy volunteers.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2005 Nov; 20(11):2582-3. doi:
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Therapeutic drug monitoring.
2005 Aug; 27(4):509-20. doi:
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International journal of pharmaceutics.
2005 Jul; 298(1):38-46. doi:
10.1016/j.ijpharm.2005.03.014. [PMID: 15890479] - Dae Y Lee, Ji Y Kim, Yu C Kim, Jong W Kwon, Won B Kim, Myung G Lee. Dose-independent pharmacokinetics of torasemide after intravenous and oral administration to rats.
Biopharmaceutics & drug disposition.
2005 Jul; 26(5):173-82. doi:
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Journal of clinical neurology (Seoul, Korea).
2005 Apr; 1(1):92-6. doi:
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Renal failure.
2005; 27(4):385-92. doi:
10.1081/jdi-65298. [PMID: 16060124] - Salvatore Paterna, Sergio Fasullo, Pietro Di Pasquale. High-Dose Torasemide is Equivalent to High-Dose Furosemide with Hypertonic Saline in the Treatment of Refractory Congestive Heart Failure.
Clinical drug investigation.
2005; 25(3):165-73. doi:
10.2165/00044011-200525030-00002. [PMID: 17523765] - Stefan Viktor Vormfelde, Sabine Engelhardt, Alexandra Zirk, Ingolf Meineke, Franziska Tuchen, Julia Kirchheiner, Jürgen Brockmöller. CYP2C9 polymorphisms and the interindividual variability in pharmacokinetics and pharmacodynamics of the loop diuretic drug torsemide.
Clinical pharmacology and therapeutics.
2004 Dec; 76(6):557-66. doi:
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Prostaglandins & other lipid mediators.
2004 Oct; 74(1-4):75-86. doi:
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Biopharmaceutics & drug disposition.
2004 Jul; 25(5):211-8. doi:
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Journal of the American College of Cardiology.
2004 Jun; 43(11):2028-35. doi:
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Pharmacotherapy.
2004 May; 24(5):630-7. doi:
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