ACESULFAME (BioDeep_00000397763)

   


代谢物信息卡片


ACESULFAME

化学式: C4H5NO4S (162.993929)
中文名称: 安赛蜜
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CC(=O)NS(=O)(=O)O1
InChI: InChI=1S/C4H5NO4S/c1-3-2-4(6)5-10(7,8)9-3/h2H,1H3,(H,5,6)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 963; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1249; ORIGINAL_PRECURSOR_SCAN_NO 1248
CONFIDENCE standard compound; INTERNAL_ID 963; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1271; ORIGINAL_PRECURSOR_SCAN_NO 1270
CONFIDENCE standard compound; INTERNAL_ID 963; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1265; ORIGINAL_PRECURSOR_SCAN_NO 1264
CONFIDENCE standard compound; INTERNAL_ID 963; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1264; ORIGINAL_PRECURSOR_SCAN_NO 1263
CONFIDENCE standard compound; INTERNAL_ID 963; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1253; ORIGINAL_PRECURSOR_SCAN_NO 1252
CONFIDENCE standard compound; INTERNAL_ID 963; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 1263; ORIGINAL_PRECURSOR_SCAN_NO 1262
CONFIDENCE standard compound; INTERNAL_ID 2377
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2756

同义名列表

1 个代谢物同义名

ACESULFAME



数据库引用编号

27 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Shuang Qiao, Wendy Huang, Darina Kuzma, Aleshia Kormendi. Acesulfame and other artificial sweeteners in a wastewater treatment plant in Alberta, Canada: Occurrence, degradation, and emission. Chemosphere. 2024 May; 356(?):141893. doi: 10.1016/j.chemosphere.2024.141893. [PMID: 38582168]
  • Xiaoyan Ma, Sinong Huang, Yuhong Jin, Hui Liao, Shaoning Chen, Hong Wang, Weijie Zhang, Yifei Wu, Weiwei Bi, Xueyan Li, Andrea M Dietrich. Domesticating aquatic plants in hydroponic systems to demonstrate and advance phytoremediation of the artificial sweetener acesulfame. The Science of the total environment. 2023 Sep; 892(?):164806. doi: 10.1016/j.scitotenv.2023.164806. [PMID: 37308013]
  • Miguel Angel Marazuela, Giovanni Formentin, Klaus Erlmeier, Thilo Hofmann. Acesulfame allows the tracing of multiple sources of wastewater and riverbank filtration. Environmental pollution (Barking, Essex : 1987). 2023 Apr; 323(?):121223. doi: 10.1016/j.envpol.2023.121223. [PMID: 36754203]
  • Haiyang Li, Xuehua Fan, Xiangxiang Wu, Yousong Yue, Chenxu Li, Xinjing Gui, Yanli Wang, Jing Yao, Junming Wang, Lu Zhang, Xuelin Li, Junhan Shi, Ruixin Liu. Study on the taste-masking effect and mechanism of Acesulfame K on berberine hydrochloride. Drug development and industrial pharmacy. 2023 Jan; 49(1):92-102. doi: 10.1080/03639045.2023.2183713. [PMID: 36859792]
  • Aishwarya Murali, Varun Giri, Hunter James Cameron, Saskia Sperber, Franziska Maria Zickgraf, Volker Haake, Peter Driemert, Tilmann Walk, Hennicke Kamp, Ivonne McM Rietjens, Bennard van Ravenzwaay. Investigating the gut microbiome and metabolome following treatment with artificial sweeteners acesulfame potassium and saccharin in young adult Wistar rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022 Jul; 165(?):113123. doi: 10.1016/j.fct.2022.113123. [PMID: 35588986]
  • Cheng-Hsin Lin, Hung-Yuan Li, Shu-Huei Wang, Yue-Hwa Chen, Yang-Ching Chen, Hung-Tsung Wu. Consumption of Non-Nutritive Sweetener, Acesulfame Potassium Exacerbates Atherosclerosis through Dysregulation of Lipid Metabolism in ApoE-/- Mice. Nutrients. 2021 Nov; 13(11):. doi: 10.3390/nu13113984. [PMID: 34836239]
  • Yoshinori Hanawa, Masaaki Higashiyama, Chie Kurihara, Rina Tanemoto, Suguru Ito, Akinori Mizoguchi, Shin Nishii, Akinori Wada, Kenichi Inaba, Nao Sugihara, Kazuki Horiuchi, Yoshikiyo Okada, Kazuyuki Narimatsu, Shunsuke Komoto, Kengo Tomita, Ryota Hokari. Acesulfame potassium induces dysbiosis and intestinal injury with enhanced lymphocyte migration to intestinal mucosa. Journal of gastroenterology and hepatology. 2021 Nov; 36(11):3140-3148. doi: 10.1111/jgh.15654. [PMID: 34368996]
  • Jean-B Sérodes, Sonja Behmel, Sabrina Simard, Olivier Laflamme, Antoine Grondin, Christine Beaulieu, François Proulx, Manuel J Rodriguez. Tracking domestic wastewater and road de-icing salt in a municipal drinking water reservoir: Acesulfame and chloride as co-tracers. Water research. 2021 Sep; 203(?):117493. doi: 10.1016/j.watres.2021.117493. [PMID: 34365194]
  • Jianhui Zhu, Jiaxin Liu, Zhengyi Li, Ranhui Xi, Yuqing Li, Xian Peng, Xin Xu, Xin Zheng, Xuedong Zhou. The Effects of Nonnutritive Sweeteners on the Cariogenic Potential of Oral Microbiome. BioMed research international. 2021; 2021(?):9967035. doi: 10.1155/2021/9967035. [PMID: 34258285]
  • Hongmei Zhang, Hao Deng, Yanqing Wang. Comprehensive investigations about the binding interaction of acesulfame with human serum albumin. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2020 Aug; 237(?):118410. doi: 10.1016/j.saa.2020.118410. [PMID: 32361316]
  • Yali Xu, Ke Li, Yubin Liu, Zhen Liu, Lei Wang, Jian Pu, Zhen Xu, Hongwen Sun. Combined effects of artificial sweetener acesulfame on the uptake of Cd in rice (Oryza sativa L.). Environmental pollution (Barking, Essex : 1987). 2019 Sep; 252(Pt A):171-179. doi: 10.1016/j.envpol.2019.05.113. [PMID: 31146232]
  • Hyoun-Tae Hwang, S K Frey, Young-Jin Park, K D M Pintar, D R Lapen, J L Thomas, J Spoelstra, S L Schiff, S J Brown, E A Sudicky. Estimating cumulative wastewater treatment plant discharge influences on acesulfame and Escherichia coli in a highly impacted watershed with a fully-integrated modelling approach. Water research. 2019 Jun; 157(?):647-662. doi: 10.1016/j.watres.2019.03.041. [PMID: 31004980]
  • Katja Ribbers, Lutz Breuer, Rolf-Alexander Düring. Detection of artificial sweeteners and iodinated X-ray contrast media in wastewater via LC-MS/MS and their potential use as anthropogenic tracers in flowing waters. Chemosphere. 2019 Mar; 218(?):189-196. doi: 10.1016/j.chemosphere.2018.10.193. [PMID: 30471499]
  • Claudia Cruz-Rojas, Nely SanJuan-Reyes, María Paulina Aideé Gracia Fuentes-Benites, Octavio Dublan-García, Marcela Galar-Martínez, Hariz Islas-Flores, Leobardo Manuel Gómez-Oliván. Acesulfame potassium: Its ecotoxicity measured through oxidative stress biomarkers in common carp (Cyprinus carpio). The Science of the total environment. 2019 Jan; 647(?):772-784. doi: 10.1016/j.scitotenv.2018.08.034. [PMID: 30096667]
  • Joanna Doummar, Michel Aoun. Assessment of the origin and transport of four selected emerging micropollutants sucralose, Acesulfame-K, gemfibrozil, and iohexol in a karst spring during a multi-event spring response. Journal of contaminant hydrology. 2018 08; 215(?):11-20. doi: 10.1016/j.jconhyd.2018.06.003. [PMID: 29983209]
  • Daisuke Ibi, Fumika Suzuki, Masayuki Hiramatsu. Effect of AceK (acesulfame potassium) on brain function under dietary restriction in mice. Physiology & behavior. 2018 05; 188(?):291-297. doi: 10.1016/j.physbeh.2018.02.024. [PMID: 29458115]
  • Kristina I Rother, Allison C Sylvetsky, Peter J Walter, H Martin Garraffo, David A Fields. Pharmacokinetics of Sucralose and Acesulfame-Potassium in Breast Milk Following Ingestion of Diet Soda. Journal of pediatric gastroenterology and nutrition. 2018 03; 66(3):466-470. doi: 10.1097/mpg.0000000000001817. [PMID: 29077645]
  • Ling Ma, Yarui Liu, Jiayao Xu, Hongwen Sun, Hao Chen, Yiming Yao, Peng Zhang, Fengju Shen, Aldredo C Alder. Mass loading of typical artificial sweeteners in a pig farm and their dissipation and uptake by plants in neighboring farmland. The Science of the total environment. 2017 Dec; 605-606(?):735-744. doi: 10.1016/j.scitotenv.2017.06.027. [PMID: 28675883]
  • Caomhan Logue, Le Roy C Dowey, J J Strain, Hans Verhagen, Stephen McClean, Alison M Gallagher. Application of Liquid Chromatography-Tandem Mass Spectrometry To Determine Urinary Concentrations of Five Commonly Used Low-Calorie Sweeteners: A Novel Biomarker Approach for Assessing Recent Intakes?. Journal of agricultural and food chemistry. 2017 Jun; 65(22):4516-4525. doi: 10.1021/acs.jafc.7b00404. [PMID: 28506059]
  • Takashi Uebanso, Ai Ohnishi, Reiko Kitayama, Ayumi Yoshimoto, Mutsumi Nakahashi, Takaaki Shimohata, Kazuaki Mawatari, Akira Takahashi. Effects of Low-Dose Non-Caloric Sweetener Consumption on Gut Microbiota in Mice. Nutrients. 2017 Jun; 9(6):. doi: 10.3390/nu9060560. [PMID: 28587159]
  • Florian R Storck, Christian Skark, Frank Remmler, Heinz-Jürgen Brauch. Environmental fate and behavior of acesulfame in laboratory experiments. Water science and technology : a journal of the International Association on Water Pollution Research. 2016 Dec; 74(12):2832-2842. doi: 10.2166/wst.2016.452. [PMID: 27997393]
  • Ngoc Han Tran, Jie Gan, Viet Tung Nguyen, Huiting Chen, Luhua You, Ankur Duarah, Lifeng Zhang, Karina Yew-Hoong Gin. Sorption and biodegradation of artificial sweeteners in activated sludge processes. Bioresource technology. 2015 Dec; 197(?):329-38. doi: 10.1016/j.biortech.2015.08.083. [PMID: 26342347]
  • Kristina I Rother, Allison C Sylvetsky, S S Schiffman. Non-nutritive sweeteners in breast milk: perspective on potential implications of recent findings. Archives of toxicology. 2015 Nov; 89(11):2169-71. doi: 10.1007/s00204-015-1611-9. [PMID: 26462668]
  • Cara L Frankenfeld, Masoumeh Sikaroodi, Evan Lamb, Sarah Shoemaker, Patrick M Gillevet. High-intensity sweetener consumption and gut microbiome content and predicted gene function in a cross-sectional study of adults in the United States. Annals of epidemiology. 2015 Oct; 25(10):736-42.e4. doi: 10.1016/j.annepidem.2015.06.083. [PMID: 26272781]
  • Armorel Diane van Eyk. The effect of five artificial sweeteners on Caco-2, HT-29 and HEK-293 cells. Drug and chemical toxicology. 2015; 38(3):318-27. doi: 10.3109/01480545.2014.966381. [PMID: 25317478]
  • Allison C Sylvetsky, Alexandra L Gardner, Viviana Bauman, Jenny E Blau, H Martin Garraffo, Peter J Walter, Kristina I Rother. Nonnutritive Sweeteners in Breast Milk. Journal of toxicology and environmental health. Part A. 2015; 78(16):1029-32. doi: 10.1080/15287394.2015.1053646. [PMID: 26267522]
  • YingYing Liu, David W Blowes, Laura Groza, Michelle J Sabourin, Carol J Ptacek. Acesulfame-K and pharmaceuticals as co-tracers of municipal wastewater in a receiving river. Environmental science. Processes & impacts. 2014 Dec; 16(12):2789-95. doi: 10.1039/c4em00237g. [PMID: 25359282]
  • Yoshiaki Ohtsu, Yuko Nakagawa, Masahiro Nagasawa, Shigeki Takeda, Hirokazu Arakawa, Itaru Kojima. Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells. Molecular and cellular endocrinology. 2014 Aug; 394(1-2):70-9. doi: 10.1016/j.mce.2014.07.004. [PMID: 25017733]
  • Janina S G Diogo, Liliana S O Silva, Angelina Pena, Celeste M Lino. Risk assessment of additives through soft drinks and nectars consumption on Portuguese population: a 2010 survey. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2013 Dec; 62(?):548-53. doi: 10.1016/j.fct.2013.09.006. [PMID: 24036138]
  • Zhiwei Gan, Hongwen Sun, Biting Feng, Ruonan Wang, Yanwei Zhang. Occurrence of seven artificial sweeteners in the aquatic environment and precipitation of Tianjin, China. Water research. 2013 Sep; 47(14):4928-37. doi: 10.1016/j.watres.2013.05.038. [PMID: 23866151]
  • Yuko Nakagawa, Masahiro Nagasawa, Hideo Mogami, Martin Lohse, Yuzo Ninomiya, Itaru Kojima. Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists. Endocrine journal. 2013; 60(10):1191-206. doi: 10.1507/endocrj.ej13-0282. [PMID: 23933592]
  • Wei-na Cong, Rui Wang, Huan Cai, Caitlin M Daimon, Morten Scheibye-Knudsen, Vilhelm A Bohr, Rebecca Turkin, William H Wood, Kevin G Becker, Ruin Moaddel, Stuart Maudsley, Bronwen Martin. Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. PloS one. 2013; 8(8):e70257. doi: 10.1371/journal.pone.0070257. [PMID: 23950916]
  • Gry T Dahl, Berit Woldseth, Rolf Lindemann. Metabolic acidosis mimicking diabetic ketoacidosis after use of calorie-free mineral water. European journal of pediatrics. 2012 Sep; 171(9):1405-7. doi: 10.1007/s00431-012-1723-7. [PMID: 22457081]
  • Marco Scheurer, Markus Godejohann, Arne Wick, Oliver Happel, Thomas A Ternes, Heinz-Jürgen Brauch, Wolfgang K L Ruck, Frank Thomas Lange. Structural elucidation of main ozonation products of the artificial sweeteners cyclamate and acesulfame. Environmental science and pollution research international. 2012 May; 19(4):1107-18. doi: 10.1007/s11356-011-0618-x. [PMID: 21964549]
  • Maartje C P Geraedts, Freddy J Troost, Wim H M Saris. Addition of sucralose enhances the release of satiety hormones in combination with pea protein. Molecular nutrition & food research. 2012 Mar; 56(3):417-24. doi: 10.1002/mnfr.201100297. [PMID: 22378494]
  • Robert E Steinert, Florian Frey, Antonia Töpfer, Jürgen Drewe, Christoph Beglinger. Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides. The British journal of nutrition. 2011 May; 105(9):1320-8. doi: 10.1017/s000711451000512x. [PMID: 21255472]
  • Wookju Jang, Nam Ho Jeoung, Kyung-Hyun Cho. Modified apolipoprotein (apo) A-I by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state. Molecules and cells. 2011 May; 31(5):461-70. doi: 10.1007/s10059-011-1009-3. [PMID: 21533907]
  • Ignaz J Buerge, Martina Keller, Hans-Rudolf Buser, Markus D Müller, Thomas Poiger. Saccharin and other artificial sweeteners in soils: estimated inputs from agriculture and households, degradation, and leaching to groundwater. Environmental science & technology. 2011 Jan; 45(2):615-21. doi: 10.1021/es1031272. [PMID: 21142066]
  • Rebecca J Brown, Mary Walter, Kristina I Rother. Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion. Diabetes care. 2009 Dec; 32(12):2184-6. doi: 10.2337/dc09-1185. [PMID: 19808921]
  • Kevin D Ballard, Richard S Bruno, Richard L Seip, Erin E Quann, Brittanie M Volk, Daniel J Freidenreich, Diana M Kawiecki, Brian R Kupchak, Min-Yu Chung, William J Kraemer, Jeff S Volek. Acute ingestion of a novel whey-derived peptide improves vascular endothelial responses in healthy individuals: a randomized, placebo controlled trial. Nutrition journal. 2009 Jul; 8(?):34. doi: 10.1186/1475-2891-8-34. [PMID: 19624856]
  • Ignaz J Buerge, Hans-Rudolf Buser, Maren Kahle, Markus D Müller, Thomas Poiger. Ubiquitous occurrence of the artificial sweetener acesulfame in the aquatic environment: an ideal chemical marker of domestic wastewater in groundwater. Environmental science & technology. 2009 Jun; 43(12):4381-5. doi: 10.1021/es900126x. [PMID: 19603650]
  • Yukihiro Fujita, Rhonda D Wideman, Madeleine Speck, Ali Asadi, David S King, Travis D Webber, Masakazu Haneda, Timothy J Kieffer. Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo. American journal of physiology. Endocrinology and metabolism. 2009 Mar; 296(3):E473-9. doi: 10.1152/ajpendo.90636.2008. [PMID: 19106249]
  • Joaquín Pérez-Guisado, Andrés Muñoz-Serrano, Angeles Alonso-Moraga. Spanish Ketogenic Mediterranean Diet: a healthy cardiovascular diet for weight loss. Nutrition journal. 2008 Oct; 7(?):30. doi: 10.1186/1475-2891-7-30. [PMID: 18950537]
  • Céline E Riera, Horst Vogel, Sidney A Simon, Johannes le Coutre. Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptors. American journal of physiology. Regulatory, integrative and comparative physiology. 2007 Aug; 293(2):R626-34. doi: 10.1152/ajpregu.00286.2007. [PMID: 17567713]
  • Bonnie M King, Paul Arents, N Bouter, C A A Duineveld, M Meyners, S I Schroff, S T Soekhai. Sweetener/sweetness-induced changes in flavor perception and flavor release of fruity and green character in beverages. Journal of agricultural and food chemistry. 2006 Apr; 54(7):2671-7. doi: 10.1021/jf060195f. [PMID: 16569060]
  • Christina Kuhn, Bernd Bufe, Marcel Winnig, Thomas Hofmann, Oliver Frank, Maik Behrens, Tatjana Lewtschenko, Jay P Slack, Cynthia D Ward, Wolfgang Meyerhof. Bitter taste receptors for saccharin and acesulfame K. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004 Nov; 24(45):10260-5. doi: 10.1523/jneurosci.1225-04.2004. [PMID: 15537898]
  • Peihua Jiang, Qingzhou Ji, Zhan Liu, Lenore A Snyder, Lumie M J Benard, Robert F Margolskee, Marianna Max. The cysteine-rich region of T1R3 determines responses to intensely sweet proteins. The Journal of biological chemistry. 2004 Oct; 279(43):45068-75. doi: 10.1074/jbc.m406779200. [PMID: 15299024]
  • D P Nikolelis, S Pantoulias. Selective continuous monitoring and analysis of mixtures of acesulfame-K, cyclamate, and saccharin in artificial sweetener tablets, diet soft drinks, yogurts, and wines using filter-supported bilayer lipid membranes. Analytical chemistry. 2001 Dec; 73(24):5945-52. doi: 10.1021/ac010559x. [PMID: 11791564]
  • M Inoue, S A McCaughey, A A Bachmanov, G K Beauchamp. Whole nerve chorda tympani responses to sweeteners in C57BL/6ByJ and 129P3/J mice. Chemical senses. 2001 Sep; 26(7):915-23. doi: 10.1093/chemse/26.7.915. [PMID: 11555486]
  • B Bufe, H Schmale, W Meyerhof. Induction of membrane chloride currents in Xenopus laevis oocytes by the sulfonyl amide sweeteners acesulfame K and saccharin. Journal of receptor and signal transduction research. 2000 May; 20(2-3):153-66. doi: 10.3109/10799890009150642. [PMID: 10994651]
  • L A Wilson, K Wilkinson, H M Crews, A M Davies, C S Dick, V L Dumsday. Urinary monitoring of saccharin and acesulfame-K as biomarkers of exposure to these additives. Food additives and contaminants. 1999 Jun; 16(6):227-38. doi: 10.1080/026520399283993. [PMID: 10560576]
  • T H Grenby. High-potency sweeteners and dental health. The Ohio dental journal. 1990 Sep; 64(2):15-6, 18. doi: ". [PMID: 2098676]
  • Y Liang, G Steinbach, V Maier, E F Pfeiffer. The effect of artificial sweetener on insulin secretion. 1. The effect of acesulfame K on insulin secretion in the rat (studies in vivo). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1987 Jun; 19(6):233-8. doi: 10.1055/s-2007-1011788. [PMID: 2887500]
  • Ia L Germaniuk. [Artificial saccharose substitutes in diseases with disordered carbohydrate and lipid metabolism]. Vrachebnoe delo. 1986 Aug; ?(8):63-7. doi: ". [PMID: 3535254]
  • G Hellekant, C H af Segerstad, T Roberts, H van der Wel, J N Brouwer, D Glaser, R Haynes, J W Eichberg. Effects of gymnemic acid on the chorda tympani proper nerve responses to sweet, sour, salty and bitter taste stimuli in the chimpanzee. Acta physiologica Scandinavica. 1985 Jul; 124(3):399-408. doi: 10.1111/j.1748-1716.1985.tb07675.x. [PMID: 4050473]