Perfluorovaleric acid (BioDeep_00000397753)
代谢物信息卡片
Perfluoropentanoic acid (PFPeA)
化学式: C5HF9O2 (263.98328339999995)
中文名称: 九氟戊酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=O)(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)O
InChI: InChI=1S/C5HF9O2/c6-2(7,1(15)16)3(8,9)4(10,11)5(12,13)14/h(H,15,16)
描述信息
CONFIDENCE standard compound; INTERNAL_ID 5945
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2714
同义名列表
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Emily Marques, Marisa Pfohl, Wei Wei, Giuseppe Tarantola, Lucie Ford, Ogochukwu Amaeze, Jessica Alesio, Sangwoo Ryu, Xuelian Jia, Hao Zhu, Geoffrey D Bothun, Angela Slitt. Replacement per- and polyfluoroalkyl substances (PFAS) are potent modulators of lipogenic and drug metabolizing gene expression signatures in primary human hepatocytes.
Toxicology and applied pharmacology.
2022 05; 442(?):115991. doi:
10.1016/j.taap.2022.115991. [PMID: 35337807] - Go-Wun Choi, Eun-Jeong Choi, Ju Hee Kim, Dong Wook Kang, Yong-Bok Lee, Hea-Young Cho. Gender differences in pharmacokinetics of perfluoropentanoic acid using non-linear mixed-effect modeling in rats.
Archives of toxicology.
2020 05; 94(5):1601-1612. doi:
10.1007/s00204-020-02705-6. [PMID: 32170342] - Jianzhong Wen, Weixun Wang, Keun-Joong Lee, Bernard K Choi, Paul Harradine, Gino M Salituro, Lucinda Hittle. Quantitation of Super Basic Peptides in Biological Matrices by a Generic Perfluoropentanoic Acid-Based Liquid Chromatography-Mass Spectrometry Method.
Journal of the American Society for Mass Spectrometry.
2019 Sep; 30(9):1779-1789. doi:
10.1007/s13361-019-02257-9. [PMID: 31250320] - Shuyan Zhao, Tiankun Liang, Lingyan Zhu, Liping Yang, Tianqi Liu, Jia Fu, Bohui Wang, Jingjing Zhan, Lifen Liu. Fate of 6:2 fluorotelomer sulfonic acid in pumpkin (Cucurbita maxima L.) based on hydroponic culture: Uptake, translocation and biotransformation.
Environmental pollution (Barking, Essex : 1987).
2019 Sep; 252(Pt A):804-812. doi:
10.1016/j.envpol.2019.06.020. [PMID: 31200206] - Xingren Pan, Pengfei Qin, Rutao Liu, Wanni Yu, Xiaofei Dong. Effects of Carbon Chain Length on the Perfluoroalkyl Acids-Induced Oxidative Stress of Erythrocytes in Vitro.
Journal of agricultural and food chemistry.
2018 Jun; 66(25):6414-6420. doi:
10.1021/acs.jafc.8b02197. [PMID: 29860827] - Jingduan Chi, Yonghua Ling, Rand Jenkins, Fumin Li. Quantitation of levodopa and carbidopa in rat plasma by LC-MS/MS: The key role of ion-pairing reversed-phase chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Jun; 1054(?):1-9. doi:
10.1016/j.jchromb.2017.04.001. [PMID: 28412665] - Geary W Olsen, Cleston C Lange, Mark E Ellefson, David C Mair, Timothy R Church, Corinne L Goldberg, Ross M Herron, Zahra Medhdizadehkashi, John B Nobiletti, Jorge A Rios, William K Reagen, Larry R Zobel. Temporal trends of perfluoroalkyl concentrations in American Red Cross adult blood donors, 2000-2010.
Environmental science & technology.
2012 Jun; 46(11):6330-8. doi:
10.1021/es300604p. [PMID: 22554481] - Heather N Bischel, Laura A Macmanus-Spencer, Chaojie Zhang, Richard G Luthy. Strong associations of short-chain perfluoroalkyl acids with serum albumin and investigation of binding mechanisms.
Environmental toxicology and chemistry.
2011 Nov; 30(11):2423-30. doi:
10.1002/etc.647. [PMID: 21842491] - Geary W Olsen, Mark E Ellefson, David C Mair, Timothy R Church, Corinne L Goldberg, Ross M Herron, Zahra Medhdizadehkashi, John B Nobiletti, Jorge A Rios, William K Reagen, Larry R Zobel. Analysis of a homologous series of perfluorocarboxylates from American Red Cross adult blood donors, 2000-2001 and 2006.
Environmental science & technology.
2011 Oct; 45(19):8022-9. doi:
10.1021/es1043535. [PMID: 21528903] - Jessica C D'eon, Scott A Mabury. Exploring indirect sources of human exposure to perfluoroalkyl carboxylates (PFCAs): evaluating uptake, elimination, and biotransformation of polyfluoroalkyl phosphate esters (PAPs) in the rat.
Environmental health perspectives.
2011 Mar; 119(3):344-50. doi:
10.1289/ehp.1002409. [PMID: 21059488] - Zohara Sternberg, Cassandra Hennies, Daniel Sternberg, Ping Wang, Peter Kinkel, David Hojnacki, Bianca Weinstock-Guttmann, Frederick Munschauer. Diagnostic potential of plasma carboxymethyllysine and carboxyethyllysine in multiple sclerosis.
Journal of neuroinflammation.
2010 Oct; 7(?):72. doi:
10.1186/1742-2094-7-72. [PMID: 21034482] - Pengfei Qin, Rutao Liu, Xingren Pan, Xiaoyan Fang, Yue Mou. Impact of carbon chain length on binding of perfluoroalkyl acids to bovine serum albumin determined by spectroscopic methods.
Journal of agricultural and food chemistry.
2010 May; 58(9):5561-7. doi:
10.1021/jf100412q. [PMID: 20397730] - Ching-Hui Yang, Kyle P Glover, Xing Han. Organic anion transporting polypeptide (Oatp) 1a1-mediated perfluorooctanoate transport and evidence for a renal reabsorption mechanism of Oatp1a1 in renal elimination of perfluorocarboxylates in rats.
Toxicology letters.
2009 Oct; 190(2):163-71. doi:
10.1016/j.toxlet.2009.07.011. [PMID: 19616083] - Brad L Upham, Joon-Suk Park, Pavel Babica, Iva Sovadinova, Alisa M Rummel, James E Trosko, Akihiko Hirose, Ryuichi Hasegawa, Jun Kanno, Kimie Sai. Structure-activity-dependent regulation of cell communication by perfluorinated fatty acids using in vivo and in vitro model systems.
Environmental health perspectives.
2009 Apr; 117(4):545-51. doi:
10.1289/ehp.11728. [PMID: 19440492] - Michael Wilhelm, Jürgen Hölzer, Lorenz Dobler, Knut Rauchfuss, Oliver Midasch, Martin Kraft, Jürgen Angerer, Gerhard Wiesmüller. Preliminary observations on perfluorinated compounds in plasma samples (1977-2004) of young German adults from an area with perfluorooctanoate-contaminated drinking water.
International journal of hygiene and environmental health.
2009 Mar; 212(2):142-5. doi:
10.1016/j.ijheh.2008.04.008. [PMID: 18550432] - Jürgen Hölzer, Oliver Midasch, Knut Rauchfuss, Martin Kraft, Rolf Reupert, Jürgen Angerer, Peter Kleeschulte, Nina Marschall, Michael Wilhelm. Biomonitoring of perfluorinated compounds in children and adults exposed to perfluorooctanoate-contaminated drinking water.
Environmental health perspectives.
2008 May; 116(5):651-7. doi:
10.1289/ehp.11064. [PMID: 18470314] - Marica Orioli, Giancarlo Aldini, Maria Carmela Benfatto, Roberto Maffei Facino, Marina Carini. HNE Michael adducts to histidine and histidine-containing peptides as biomarkers of lipid-derived carbonyl stress in urines: LC-MS/MS profiling in Zucker obese rats.
Analytical chemistry.
2007 Dec; 79(23):9174-84. doi:
10.1021/ac7016184. [PMID: 17979257] - Songmei Gao, Siddhartha Bhoopathy, Zong-Ping Zhang, D Scott Wright, Rand Jenkins, H Thomas Karnes. Evaluation of volatile ion-pair reagents for the liquid chromatography-mass spectrometry analysis of polar compounds and its application to the determination of methadone in human plasma.
Journal of pharmaceutical and biomedical analysis.
2006 Feb; 40(3):679-88. doi:
10.1016/j.jpba.2005.05.022. [PMID: 16029944] - J Y Kwon, M Moini. Analysis of underivatized amino acid mixtures using high performance liquid chromatography/dual oscillating nebulizer atmospheric pressure microwave induced plasma ionization-mass spectrometry.
Journal of the American Society for Mass Spectrometry.
2001 Jan; 12(1):117-22. doi:
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Journal of medicinal chemistry.
1992 Mar; 35(5):944-53. doi:
10.1021/jm00083a021. [PMID: 1548684] - R Erkkola, J Kanto, L Kangas, O Piiroinen. Feto-maternal concentrations of diazepam and W-demethyldiazepam after intra-amniotic diazepam injection.
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