Kathon 930 (BioDeep_00000397736)
代谢物信息卡片
化学式: C11H17Cl2NOS (281.0407852)
中文名称: 4,5-二氯-2-正辛基-4-异噻唑啉-3-酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCN1C(=O)C(=C(S1)Cl)Cl
InChI: InChI=1S/C11H17Cl2NOS/c1-2-3-4-5-6-7-8-14-11(15)9(12)10(13)16-14/h2-8H2,1H3
描述信息
CONFIDENCE standard compound; EAWAG_UCHEM_ID 344
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Adriano Rayol da Silva, Amanda da Silveira Guerreiro, Samantha Eslava Martins, Juliana Zomer Sandrini. DCOIT unbalances the antioxidant defense system in juvenile and adults of the marine bivalve Amarilladesma mactroides (Mollusca: Bivalvia).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2021 Dec; 250(?):109169. doi:
10.1016/j.cbpc.2021.109169. [PMID: 34418533] - Hye-Jin Eom, Md Niamul Haque, Sang-Eun Nam, Do-Hee Lee, Jae-Sung Rhee. Effects of sublethal concentrations of the antifouling biocide Sea-Nine on biochemical parameters of the marine polychaete Perinereis aibuhitensis.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2019 Aug; 222(?):125-134. doi:
10.1016/j.cbpc.2019.05.001. [PMID: 31055069] - Yujie Su, Huifeng Li, Chang Xu, Xiaodan Wang, Jia Xie, Jian G Qin, Liqiao Chen, Erchao Li. Endoplasmic reticulum stress mediates 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT)-induced toxicity and liver lipid metabolism changes in Nile tilapia (Oreochromis niloticus).
Environmental pollution (Barking, Essex : 1987).
2018 Nov; 242(Pt B):1981-1987. doi:
10.1016/j.envpol.2018.07.046. [PMID: 30097282] - Lianguo Chen, Doris W T Au, Chenyan Hu, Drew R Peterson, Bingsheng Zhou, Pei-Yuan Qian. Identification of Molecular Targets for 4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) in Teleosts: New Insight into Mechanism of Toxicity.
Environmental science & technology.
2017 02; 51(3):1840-1847. doi:
10.1021/acs.est.6b05523. [PMID: 28026967] - Lianguo Chen, Weipeng Zhang, Rui Ye, Chenyan Hu, Qiangwei Wang, Frauke Seemann, Doris W T Au, Bingsheng Zhou, John P Giesy, Pei-Yuan Qian. Chronic Exposure of Marine Medaka (Oryzias melastigma) to 4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) Reveals Its Mechanism of Action in Endocrine Disruption via the Hypothalamus-Pituitary-Gonadal-Liver (HPGL) Axis.
Environmental science & technology.
2016 Apr; 50(8):4492-501. doi:
10.1021/acs.est.6b01137. [PMID: 27035644] - Lianguo Chen, Rui Ye, Ying Xu, Zhaoming Gao, Doris W T Au, Pei-Yuan Qian. Comparative safety of the antifouling compound butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) to the marine medaka (Oryzias melastigma).
Aquatic toxicology (Amsterdam, Netherlands).
2014 Apr; 149(?):116-25. doi:
10.1016/j.aquatox.2014.01.023. [PMID: 24583292] - Jürgen Arning, Ralf Dringen, Maike Schmidt, Anette Thiessen, Stefan Stolte, Marianne Matzke, Ulrike Bottin-Weber, Birgit Caesar-Geertz, Bernd Jastorff, Johannes Ranke. Structure-activity relationships for the impact of selected isothiazol-3-one biocides on glutathione metabolism and glutathione reductase of the human liver cell line Hep G2.
Toxicology.
2008 Apr; 246(2-3):203-12. doi:
10.1016/j.tox.2008.01.011. [PMID: 18313196] - Astrid Rafoth, Sabine Gabriel, Frank Sacher, Heinz-Jürgen Brauch. Analysis of isothiazolinones in environmental waters by gas chromatography-mass spectrometry.
Journal of chromatography. A.
2007 Sep; 1164(1-2):74-81. doi:
10.1016/j.chroma.2007.07.040. [PMID: 17681349]