Normianserin (BioDeep_00000397575)
代谢物信息卡片
化学式: C17H18N2 (250.147)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: c1ccc2c(c1)Cc3ccccc3N4C2CNCC4
InChI: InChI=1S/C17H18N2/c1-3-7-15-13(5-1)11-14-6-2-4-8-16(14)19-10-9-18-12-17(15)19/h1-8,17-18H,9-12H2
描述信息
CONFIDENCE standard compound; INTERNAL_ID 2229
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3277
同义名列表
2 个代谢物同义名
数据库引用编号
23 个数据库交叉引用编号
- ChEBI: CHEBI:188043
- PubChem: 115194
- CAS: 71936-92-0
- CAS: 76134-77-5
- MoNA: AU222911
- MoNA: AU222910
- MoNA: AU222909
- MoNA: AU222908
- MoNA: AU222907
- MoNA: EQ327709
- MoNA: EQ327708
- MoNA: EQ327707
- MoNA: EQ327706
- MoNA: EQ327705
- MoNA: EQ327704
- MoNA: EQ327703
- MoNA: EQ327702
- MoNA: EQ327701
- MoNA: AU222905
- MoNA: AU222904
- MoNA: AU222903
- MoNA: AU222902
- MoNA: AU222901
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Sarah M R Wille, Kristof E Maudens, Carlos H Van Peteghem, Willy E E Lambert. Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis.
Journal of chromatography. A.
2005 Dec; 1098(1-2):19-29. doi:
10.1016/j.chroma.2005.08.059
. [PMID: 16314157] - Bhupendrasinh Chauhan, Shubha Rani, Swati Guttikar, Anjali Zope, Nimisha Jadon, Harish Padh. Analytical method development and validation of mianserin hydrochloride and its metabolite in human plasma by LC-MS.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Sep; 823(2):69-74. doi:
10.1016/j.jchromb.2005.05.042
. [PMID: 16006201] - N Yasui, G Tybring, K Otani, K Mihara, A Suzuki, J O Svensson, S Kaneko. Effects of thioridazine, an inhibitor of CYP2D6, on the steady-state plasma concentrations of the enantiomers of mianserin and its active metabolite, desmethylmianserin, in depressed Japanese patients.
Pharmacogenetics.
1997 Oct; 7(5):369-74. doi:
10.1097/00008571-199710000-00005
. [PMID: 9352572] - G Tybring, K Otani, S Kaneko, K Mihara, Y Fukushima, L Bertilsson. Enantioselective determination of mianserin and its desmethyl metabolite in plasma during treatment of depressed Japanese patients.
Therapeutic drug monitoring.
1995 Oct; 17(5):516-21. doi:
10.1097/00007691-199510000-00013
. [PMID: 8585116] - M L Dahl, G Tybring, C E Elwin, C Alm, K Andreasson, M Gyllenpalm, L Bertilsson. Stereoselective disposition of mianserin is related to debrisoquin hydroxylation polymorphism.
Clinical pharmacology and therapeutics.
1994 Aug; 56(2):176-83. doi:
10.1038/clpt.1994.121
. [PMID: 8062494] - C B Eap, K Powell, D Campus-Souche, C Monney, D Baettig, W Taeschner, P Baumann. Determination of the enantiomers of mianserin, desmethylmianserin, and 8-hydroxymianserin in the plasma and urine of mianserin-treated patients.
Chirality.
1994; 6(7):555-63. doi:
10.1002/chir.530060708
. [PMID: 7986669] - K Otani, H Sasa, S Kaneko, T Kondo, Y Fukushima. Steady-state plasma concentrations of mianserin and its major active metabolite, desmethylmianserin.
Therapeutic drug monitoring.
1993 Apr; 15(2):113-7. doi:
10.1097/00007691-199304000-00008
. [PMID: 8503138] - K Otani, K Mihara, M Okada, O Tanaka, S Kaneko, Y Fukushima. Prediction of plasma concentrations of mianserin and desmethylmianserin at steady state from those after an initial dose of mianserin.
Therapeutic drug monitoring.
1993 Apr; 15(2):118-21. doi:
10.1097/00007691-199304000-00009
. [PMID: 8503139] - K Otani, H Sasa, H Higuchi, S Kaneko, Y Hishikawa, Y Fukushima. Subjective side effects of mianserin in relation to plasma concentrations of mianserin and desmethylmianserin.
Therapeutic drug monitoring.
1992 Jun; 14(3):190-3. doi:
10.1097/00007691-199206000-00003
. [PMID: 1412603]