Norfluoxetine (BioDeep_00000397557)
代谢物信息卡片
Norfluoxetine
化学式: C16H16F3NO (295.1183922)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)C(CCN)OC2=CC=C(C=C2)C(F)(F)F
InChI: InChI=1S/C16H16F3NO/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12/h1-9,15H,10-11,20H2
描述信息
CONFIDENCE standard compound; EAWAG_UCHEM_ID 335
CONFIDENCE standard compound; INTERNAL_ID 2112
同义名列表
1 个代谢物同义名
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:180876
- PubChem: 4541
- Metlin: METLIN96329
- ChEMBL: CHEMBL1494
- CAS: 56161-73-0
- MoNA: WA001238
- MoNA: WA001237
- MoNA: WA001236
- MoNA: WA001235
- MoNA: WA001234
- MoNA: EQ033509
- MoNA: EQ033508
- MoNA: EQ033507
- MoNA: EQ033506
- MoNA: EQ033505
- MoNA: EQ033504
- MoNA: EQ033503
- MoNA: EQ033502
- MoNA: EQ033501
- MoNA: AU211202
- MoNA: AU211201
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hyeon-Cheol Jeong, Yoon-Jee Chae, Sooyeun Lee, Wonku Kang, Hwi-Yeol Yun, Kwang-Hee Shin. Prediction of Fluoxetine and Norfluoxetine Pharmacokinetic Profiles Using Physiologically Based Pharmacokinetic Modeling.
Journal of clinical pharmacology.
2021 11; 61(11):1505-1513. doi:
10.1002/jcph.1927. [PMID: 34118174] - Julia Sagahón-Azúa, Susanna Edith Medellín-Garibay, Cinthya Eloisa Chávez-Castillo, César Guillermo González-Salinas, Rosa Del Carmen Milán-Segovia, Silvia Romano-Moreno. Factors associated with fluoxetine and norfluoxetine plasma concentrations and clinical response in Mexican patients with mental disorders.
Pharmacology research & perspectives.
2021 10; 9(5):e00864. doi:
10.1002/prp2.864. [PMID: 34523245] - P Rodrigues, V Cunha, L Oliva-Teles, M Ferreira, L Guimarães. Norfluoxetine and venlafaxine in zebrafish larvae: Single and combined toxicity of two pharmaceutical products relevant for risk assessment.
Journal of hazardous materials.
2020 12; 400(?):123171. doi:
10.1016/j.jhazmat.2020.123171. [PMID: 32593945] - A B Sioofy-Khojine, A Honkimaa, H Hyöty. A preclinical assessment to repurpose drugs to target type 1 diabetes-associated type B coxsackieviruses.
Diabetic medicine : a journal of the British Diabetic Association.
2020 11; 37(11):1849-1853. doi:
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Aquatic toxicology (Amsterdam, Netherlands).
2020 Sep; 226(?):105581. doi:
10.1016/j.aquatox.2020.105581. [PMID: 32717676] - Sevgi Başalan Över, Celal Güven, Eylem Taskin, Yusuf Sevgiler. Oxidative and apoptotic effects of fluoxetine and its metabolite norfluoxetine in Daphnia magna.
Arhiv za higijenu rada i toksikologiju.
2020 Sep; 71(3):211-222. doi:
10.2478/aiht-2020-71-3473. [PMID: 33074175] - Zheng Ren Wang, Ming Mu Hsieh. Ultrasound-assisted dispersive liquid-liquid microextraction coupled with field-amplified capillary electrophoresis for sensitive and quantitative determination of fluoxetine and norfluoxetine enantiomers in biological fluids.
Analytical and bioanalytical chemistry.
2020 Aug; 412(21):5113-5123. doi:
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