sulfapyridine (BioDeep_00000397460)

   

natural product Volatile Flavor Compounds


代谢物信息卡片


Sulfapyridine (Dagenan)

化学式: C11H11N3O2S (249.0571946)
中文名称: 磺胺吡啶
谱图信息: 最多检出来源 Homo sapiens(natural_products) 33.33%

分子结构信息

SMILES: c1(S(Nc2ccccn2)(=O)=O)ccc(N)cc1
InChI: InChI=1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EB - Short-acting sulfonamides
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent
D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
COVID info from PDB, Protein Data Bank
D003879 - Dermatologic Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
CONFIDENCE standard compound; INTERNAL_ID 2344
CONFIDENCE standard compound; INTERNAL_ID 4088
CONFIDENCE standard compound; EAWAG_UCHEM_ID 234
CONFIDENCE standard compound; INTERNAL_ID 1020

同义名列表

3 个代谢物同义名

sulfapyridine; Sulfapyridine (Dagenan); Sulfapyridine



数据库引用编号

38 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Ruyi Xu, Chen Yang, Lin Huang, Wenchao Lv, Weijuan Yang, Yongning Wu, FengFu Fu. Broad-Specificity Aptamer of Sulfonamides: Isolation and Its Application in Simultaneous Detection of Multiple Sulfonamides in Fish Sample. Journal of agricultural and food chemistry. 2022 Sep; 70(37):11804-11812. doi: 10.1021/acs.jafc.2c03423. [PMID: 36070569]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Bhupinder Kapoor, Monica Gulati, Sachin K Singh, Gopal L Khatik, Reena Gupta, Rakesh Kumar, Rajan Kumar, K Gowthamarajan, Sanjeev Mahajan, Som Gupta. Fail-safe nano-formulation of prodrug of sulfapyridine: Preparation and evaluation for treatment of rheumatoid arthritis. Materials science & engineering. C, Materials for biological applications. 2021 Jan; 118(?):111332. doi: 10.1016/j.msec.2020.111332. [PMID: 33254964]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Hilda Amekyeh, Nashiru Billa, Kah-Hay Yuen, Sheau Chin Sherlyn Lim. Effect of Food Status on the Gastrointestinal Transit of Amphotericin B-Containing Solid Lipid Nanoparticles in Rats. AAPS PharmSciTech. 2016 Oct; 17(5):1060-6. doi: 10.1208/s12249-015-0438-2. [PMID: 26511938]
  • Anne-Sophie De Koninck, Luitzen-Albert Groen, Heleen Maes, Alain Gaston Verstraete, Veronique Stove, Joris Richard Delanghe. An Unusual Type of Kidney Stone. Clinical laboratory. 2016; 62(1-2):235-9. doi: 10.7754/clin.lab.2015.150605. [PMID: 27012055]
  • Jean de Gunzburg, Annie Ducher, Christiane Modess, Danilo Wegner, Stefan Oswald, Jennifer Dressman, Violaine Augustin, Céline Feger, Antoine Andremont, Werner Weitschies, Werner Siegmund. Targeted adsorption of molecules in the colon with the novel adsorbent-based medicinal product, DAV132: A proof of concept study in healthy subjects. Journal of clinical pharmacology. 2015 Jan; 55(1):10-6. doi: 10.1002/jcph.359. [PMID: 25042595]
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  • Didier H Mathon, Sophie Palierne, Patricia Meynaud-Collard, Catherine Layssol-Lamour, Alice Dulaurent-Ferrieres, Arnaud Colson, Marlene Lacroix, Alain Bousquet-Melou, Maxence Delverdier, Andre Autefage. Laparoscopic-assisted colopexy and sterilization in male dogs: short-term results and physiologic consequences. Veterinary surgery : VS. 2011 Jun; 40(4):500-8. doi: 10.1111/j.1532-950x.2011.00835.x. [PMID: 21521243]
  • Guang-Zhi Gu, Hui-Min Xia, Zhi-Qing Pang, Zhong-Yang Liu, Xin-Guo Jiang, Jun Chen. Determination of sulphasalazine and its main metabolite sulphapyridine and 5-aminosalicylic acid in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Feb; 879(5-6):449-56. doi: 10.1016/j.jchromb.2010.12.034. [PMID: 21251889]
  • Polichronis Alivanis, Georgios Aperis, Fotini Lambrianou, Angelos Zervos, Christos Paliouras, Nikolaos Karvouniaris, Antonios Arvanitis. Reversal of refractory sulfasalazine-related renal failure after treatment with corticosteroids. Clinical therapeutics. 2010 Oct; 32(11):1906-10. doi: 10.1016/j.clinthera.2010.10.002. [PMID: 21095485]
  • Hee Ji Lee, Rosmary D Waller, Simon Stebbings, John Highton, David A Orlovich, David Schmierer, J Paul Fawcett. The effects of an orally administered probiotic on sulfasalazine metabolism in individuals with rheumatoid arthritis: a preliminary study. International journal of rheumatic diseases. 2010 Feb; 13(1):48-54. doi: 10.1111/j.1756-185x.2009.01449.x. [PMID: 20374384]
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  • Sanzhen Liu, Cheng-Ting Yeh, Tieming Ji, Kai Ying, Haiyan Wu, Ho Man Tang, Yan Fu, Daniel Nettleton, Patrick S Schnable. Mu transposon insertion sites and meiotic recombination events co-localize with epigenetic marks for open chromatin across the maize genome. PLoS genetics. 2009 Nov; 5(11):e1000733. doi: 10.1371/journal.pgen.1000733. [PMID: 19936291]
  • Jing-Jing Ma, Cun-Gang Liu, Jin-Heng Li, Xiao-Mei Cao, Sheng-Li Sun, Xuan Yao. Effects of NAT2 polymorphism on SASP pharmacokinetics in Chinese population. Clinica chimica acta; international journal of clinical chemistry. 2009 Sep; 407(1-2):30-5. doi: 10.1016/j.cca.2009.06.025. [PMID: 19560446]
  • Andrea Michaela Bauer, F Hoti, M von Korff, K Pillen, J Léon, M J Sillanpää. Advanced backcross-QTL analysis in spring barley (H. vulgare ssp. spontaneum) comparing a REML versus a Bayesian model in multi-environmental field trials. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2009 Jun; 119(1):105-23. doi: 10.1007/s00122-009-1021-6. [PMID: 19363603]
  • Christian Abegglen, Adriano Joss, Christa S McArdell, Guido Fink, Michael P Schlüsener, Thomas A Ternes, Hansruedi Siegrist. The fate of selected micropollutants in a single-house MBR. Water research. 2009 Apr; 43(7):2036-46. doi: 10.1016/j.watres.2009.02.005. [PMID: 19269669]
  • Arvo Haenni, Birgitta Sundberg, Nahid Yazdanpandah, Annika Viberg, Johan Olsson. Effect of fat emulsion (Fabuless) on orocecal transit time in healthy men. Scandinavian journal of gastroenterology. 2009; 44(10):1186-90. doi: 10.1080/00365520903131999. [PMID: 19672787]
  • Brian Quinn, François Gagné, Christian Blaise. The effects of pharmaceuticals on the regeneration of the cnidarian, Hydra attenuata. The Science of the total environment. 2008 Aug; 402(1):62-9. doi: 10.1016/j.scitotenv.2008.04.039. [PMID: 18538376]
  • D R Lapen, E Topp, C D Metcalfe, H Li, M Edwards, N Gottschall, P Bolton, W Curnoe, M Payne, A Beck. Pharmaceutical and personal care products in tile drainage following land application of municipal biosolids. The Science of the total environment. 2008 Jul; 399(1-3):50-65. doi: 10.1016/j.scitotenv.2008.02.025. [PMID: 18455753]
  • Yoshitsugu Fujioka, Yukiko Metsugi, Ken-Ichi Ogawara, Kazutaka Higaki, Toshikiro Kimura. Evaluation of in vivo dissolution behavior and GI transit of griseofulvin, a BCS class II drug. International journal of pharmaceutics. 2008 Mar; 352(1-2):36-43. doi: 10.1016/j.ijpharm.2007.10.008. [PMID: 18037251]
  • Brian Quinn, François Gagné, Christian Blaise. An investigation into the acute and chronic toxicity of eleven pharmaceuticals (and their solvents) found in wastewater effluent on the cnidarian, Hydra attenuata. The Science of the total environment. 2008 Jan; 389(2-3):306-14. doi: 10.1016/j.scitotenv.2007.08.038. [PMID: 17931692]
  • Norihide Nakada, Hiroyuki Shinohara, Ayako Murata, Kentaro Kiri, Satoshi Managaki, Nobuyuki Sato, Hideshige Takada. Removal of selected pharmaceuticals and personal care products (PPCPs) and endocrine-disrupting chemicals (EDCs) during sand filtration and ozonation at a municipal sewage treatment plant. Water research. 2007 Nov; 41(19):4373-82. doi: 10.1016/j.watres.2007.06.038. [PMID: 17632207]
  • F Gagné, C Blaise, C André. Occurrence of pharmaceutical products in a municipal effluent and toxicity to rainbow trout (Oncorhynchus mykiss) hepatocytes. Ecotoxicology and environmental safety. 2006 Jul; 64(3):329-36. doi: 10.1016/j.ecoenv.2005.04.004. [PMID: 15923035]
  • F Gagné, C Blaise, M Fournier, P D Hansen. Effects of selected pharmaceutical products on phagocytic activity in Elliptio complanata mussels. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2006 Jun; 143(2):179-86. doi: 10.1016/j.cbpc.2006.01.008. [PMID: 16533621]
  • Yan-Hong Zhou, Jie-Ping Yu, Yi-Fei Liu, Xiao-Jun Teng, Mei Ming, Peng Lv, Ping An, Shi-Quan Liu, Hong-Gang Yu. Effects of Ginkgo biloba extract on inflammatory mediators (SOD, MDA, TNF-alpha, NF-kappaBp65, IL-6) in TNBS-induced colitis in rats. Mediators of inflammation. 2006; 2006(5):92642. doi: 10.1155/mi/2006/92642. [PMID: 17392580]
  • Ravi Joshi, Sudheer Kumar, M Unnikrishnan, T Mukherjee. Free radical scavenging reactions of sulfasalazine, 5-aminosalicylic acid and sulfapyridine: mechanistic aspects and antioxidant activity. Free radical research. 2005 Nov; 39(11):1163-72. doi: 10.1080/10715760500177880. [PMID: 16298742]
  • Titus A M Msagati, Mathew Muzi Nindi. Multiresidue determination of sulfonamides in a variety of biological matrices by supported liquid membrane with high pressure liquid chromatography-electrospray mass spectrometry detection. Talanta. 2004 Sep; 64(1):87-100. doi: 10.1016/j.talanta.2004.02.038. [PMID: 18969572]
  • Craig D C Salisbury, Jason C Sweet, Roger Munro. Determination of sulfonamide residues in the tissues of food animals using automated precolumn derivatization and liquid chromatography with fluorescence detection. Journal of AOAC International. 2004 Sep; 87(5):1264-8. doi: . [PMID: 15493686]
  • S Thiele-Bruhn, T Seibicke, H-R Schulten, P Leinweber. Sorption of sulfonamide pharmaceutical antibiotics on whole soils and particle-size fractions. Journal of environmental quality. 2004 Jul; 33(4):1331-42. doi: 10.2134/jeq2004.1331. [PMID: 15254115]
  • S Thiele-Bruhn, M O Aust. Effects of pig slurry on the sorption of sulfonamide antibiotics in soil. Archives of environmental contamination and toxicology. 2004 Jul; 47(1):31-9. doi: 10.1007/s00244-003-3120-8. [PMID: 15346776]
  • Zofia Dzierzewicz, Beata Cwalina, Ludmiła Weglarz, Beata Wiśniowska, Joanna Szczerba. Susceptibility of Desulfovibrio desulfuricans intestinal strains to sulfasalazine and its biotransformation products. Medical science monitor : international medical journal of experimental and clinical research. 2004 Jun; 10(6):BR185-90. doi: NULL. [PMID: 15173665]
  • Shunichi Kumagai, Fusao Komada, Tomoko Kita, Akio Morinobu, Shoichi Ozaki, Hiroshi Ishida, Hajime Sano, Tsukasa Matsubara, Katsuhiko Okumura. N-acetyltransferase 2 genotype-related efficacy of sulfasalazine in patients with rheumatoid arthritis. Pharmaceutical research. 2004 Feb; 21(2):324-9. doi: 10.1023/b:pham.0000016246.84974.ec. [PMID: 15032315]
  • Paul J Russinko, Saraub Agarwal, Michael J Choi, Patrick J Kelty. Obstructive nephropathy secondary to sulfasalazine calculi. Urology. 2003 Oct; 62(4):748. doi: 10.1016/s0090-4295(03)00666-6. [PMID: 14550462]
  • Mickaël P Weber, Lucile J Martin, Vincent C Biourge, Patrick G Nguyen, Henri J Dumon. Influence of age and body size on orocecal transit time as assessed by use of the sulfasalazine method in healthy dogs. American journal of veterinary research. 2003 Sep; 64(9):1105-9. doi: 10.2460/ajvr.2003.64.1105. [PMID: 13677387]
  • D Teshima, B Hino, K Makino, T Yano, Y Itoh, Y Joh, M Iida, R Oishi. Sulphasalazine-induced leucopenia in a patient with renal dysfunction. Journal of clinical pharmacy and therapeutics. 2003 Jun; 28(3):239-42. doi: 10.1046/j.1365-2710.2003.00484.x. [PMID: 12795783]
  • Yuji Akiyama, Toshihisa Fujimaki, Yusei Sakurai. [Pharmacokinetics of salazosulfapyridine in a hemodialysis patient]. Ryumachi. [Rheumatism]. 2003 Jun; 43(3):569-76. doi: NULL. [PMID: 12910967]
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  • Yusuke Tanigawara, Tomoko Kita, Nobuo Aoyama, Manabu Gobara, Fusao Komada, Toshiyuki Sakai, Masato Kasuga, Hisakatsu Hatanaka, Toshiyuki Sakaeda, Katsuhiko Okumura. N-acetyltransferase 2 genotype-related sulfapyridine acetylation and its adverse events. Biological & pharmaceutical bulletin. 2002 Aug; 25(8):1058-62. doi: 10.1248/bpb.25.1058. [PMID: 12186410]
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