sulfamoxol (BioDeep_00000397459)
代谢物信息卡片
化学式: C11H13N3O3S (267.0678)
中文名称: 磺胺二甲基恶唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C)N=C(NS(=O)(=O)C2=CC=C(N)C=C2)O1
InChI: InChI=1S/C11H13N3O3S/c1-7-8(2)17-11(13-7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6H,12H2,1-2H3,(H,13,14)
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01EC - Intermediate-acting sulfonamides
A sulfonamide-based antibacterial agent where 4-aminobenzenesulfonic acid and 4,5-dimethyl-1,3-oxazol-2-amine have combined to form the sulfonamide bond.
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent
D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
CONFIDENCE standard compound; INTERNAL_ID 8; HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu)
Flow Injection; CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu)
CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu); Flow Injection
CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu)
CONFIDENCE standard compound; INTERNAL_ID 1019
同义名列表
数据库引用编号
121 个数据库交叉引用编号
- ChEBI: CHEBI:55548
- KEGGdrug: D02516
- PubChem: 12894
- Metlin: METLIN85585
- DrugBank: DB08798
- ChEMBL: CHEMBL2105399
- MeSH: Sulfamoxole
- CAS: 729-99-7
- MoNA: HB002802
- MoNA: HB002801
- MoNA: HB002800
- MoNA: HB002799
- MoNA: HB002798
- MoNA: HB002797
- MoNA: HB002619
- MoNA: HB002618
- MoNA: HB002617
- MoNA: HB002616
- MoNA: HB002615
- MoNA: HB002614
- MoNA: HB002613
- MoNA: HB002612
- MoNA: HB002611
- MoNA: HB002610
- MoNA: HB002468
- MoNA: HB002467
- MoNA: HB002466
- MoNA: HB002465
- MoNA: HB002464
- MoNA: HB002463
- MoNA: HB002462
- MoNA: HB002461
- MoNA: HB002460
- MoNA: HB002459
- MoNA: HB002458
- MoNA: HB002457
- MoNA: HB002456
- MoNA: HB002455
- MoNA: HB002454
- MoNA: HB002453
- MoNA: HB002245
- MoNA: HB002244
- MoNA: HB002243
- MoNA: HB002242
- MoNA: HB002241
- MoNA: HB002240
- MoNA: HB002239
- MoNA: HB002238
- MoNA: HB002237
- MoNA: HB002236
- MoNA: HB002235
- MoNA: HB002234
- MoNA: HB002233
- MoNA: HB002232
- MoNA: HB002231
- MoNA: HB002020
- MoNA: HB002019
- MoNA: HB002018
- MoNA: HB002017
- MoNA: HB001760
- MoNA: HB001759
- MoNA: HB001758
- MoNA: HB001757
- MoNA: HB001756
- MoNA: HB001755
- MoNA: HB001754
- MoNA: HB001753
- MoNA: HB001752
- MoNA: HB001751
- MoNA: HB001750
- MoNA: HB001749
- MoNA: HB001748
- MoNA: HB001747
- MoNA: HB001746
- MoNA: HB001745
- MoNA: HB001744
- MoNA: HB001743
- MoNA: HB001742
- MoNA: HB001741
- MoNA: HB001740
- MoNA: HB001739
- MoNA: HB001738
- MoNA: HB001737
- MoNA: HB001736
- MoNA: HB001735
- MoNA: HB001734
- MoNA: HB001733
- MoNA: HB001732
- MoNA: HB001731
- MoNA: HB001730
- MoNA: HB001729
- MoNA: HB001728
- MoNA: HB001727
- MoNA: HB001726
- MoNA: HB001725
- MoNA: HB001724
- MoNA: HB001723
- MoNA: HB001722
- MoNA: HB001721
- MoNA: HB001720
- MoNA: HB001719
- MoNA: HB001718
- MoNA: HB001717
- MoNA: HB001716
- MoNA: HB001715
- MoNA: HB001714
- MoNA: HB001713
- MoNA: HB001712
- MoNA: HB001711
- MoNA: HB001710
- MoNA: HB001709
- MoNA: HB001708
- MoNA: HB001707
- MoNA: HB001706
- MoNA: HB001705
- MoNA: HB001704
- MoNA: HB001703
- MoNA: HB001702
- MoNA: HB001701
- MoNA: AU101902
- MetaboLights: MTBLC55548
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- D G Harle, B A Baldo, J V Wells. Drugs as allergens: detection and combining site specificities of IgE antibodies to sulfamethoxazole.
Molecular immunology.
1988 Dec; 25(12):1347-54. doi:
10.1016/0161-5890(88)90050-8
. [PMID: 3237218] - S K Garg, S S Ghosh, V S Mathur. Comparative pharmacokinetic study of four different sulfonamides in combination with trimethoprim in human volunteers.
International journal of clinical pharmacology, therapy, and toxicology.
1986 Jan; 24(1):23-5. doi:
. [PMID: 3485584]
- H N Cohen, J A Fyffe, W A Ratcliffe, A M McNicol, H McIntyre, J S Kennedy, J A Thomson. Effects of trimethoprim and sulphonamide preparations on the pituitary-thyroid axis of rodents.
The Journal of endocrinology.
1981 Nov; 91(2):299-303. doi:
10.1677/joe.0.0910299
. [PMID: 6975345] - I D Watson, H N Cohen, S J McIntosh, J A Thomson, A Shenkin. Synergism between trimethoprim and sulfonamide in urine: does it exist?.
Clinical therapeutics.
1981; 4(2):103-8. doi:
NULL
. [PMID: 6975168] - K C Gupta, N K Desai, T Paul, U K Sheth. Plasma levels of trimethoprim and sulfonamide after administration of trimethoprim-sulfamethoxazole and trimethoprim-sulfamoxole.
International journal of clinical pharmacology, therapy, and toxicology.
1980 Dec; 18(12):536-7. doi:
NULL
. [PMID: 7228448] - J M Broughall, M J Bywater, H A Holt, D S Reeves. Bactericidal or bacteristatic effects of two sulphonamide plus trimethoprim preparations in human urine.
Infection.
1979; 7(3):113-8. doi:
10.1007/bf01641309
. [PMID: 478652] - N C Banerjee, M K Singh, H N Jha, S D Singh. Dispersion of sulfamoxole in tissues of poultry.
Indian journal of physiology and pharmacology.
1977 Jan; 21(1):63-5. doi:
NULL
. [PMID: 873593] - J Kuhne, F W Kohlmann, J K Seydel, E Wempe. [Pharmacokinetic studies with the combination sulfamoxole/trimethoprim in animals and men (author's transl)].
Arzneimittel-Forschung.
1976; 26(42):651-7. doi:
NULL
. [PMID: 947326] - H J Dechow, D Dölcher, G Hübner, S Kim, K Lämmerhirt, C H Pich, E Schmidt-Böthelt. [On the development of oral preparations of the combination sulfamoxole/trimethoprim (CN 3123) (author's transl)].
Arzneimittel-Forschung.
1976; 26(42):596-613. doi:
NULL
. [PMID: 947320] - E Böhni. Bacteriostatic and bactericidal activity of two trimethoprim-sulfonamide combinations.
Chemotherapy.
1976; 22(3-4):262-73. doi:
10.1159/000221933
. [PMID: 1269292] - F Lagler, R Kretzschmar, F Leuschner, E Foitzik, H Kiel, J Kuhne, W Neumann. [Toxicological investigations of the combination sulfamoxole/trimethoprim, a new broad-spectrum chemotherapeutic (author's transl)].
Arzneimittel-Forschung.
1976; 26(42):634-43. doi:
NULL
. [PMID: 947324] - M Etzel, W Wesenberg. [Clinical trial of the antibacterial combination sulfamoxole/trimethoprim (CN 3123)/Sixth communication: Results of compatibility of CN 3123 (author's transl)].
Arzneimittel-Forschung.
1976; 26(42):678-83. doi:
NULL
. [PMID: 782478] - J Gries, R Kretzschmar, J Kuhne, W Neumann, G Osterloh, R Scherschlicht, W Worstmann. [Pharmacological investigations with the combination sulfamoxole/trimethoprim, a new broadspectrum chemotherapeutic agent (author's transl)].
Arzneimittel-Forschung.
1976; 26(42):623-33. doi:
NULL
. [PMID: 947323] - E Reimerdes, J H Thumim. [Behavior of sulfanilamides in the body].
Arzneimittel-Forschung.
1970 Sep; 20(9):1171-9. doi:
NULL
. [PMID: 4922318] - B Uvnäs, B Westerholm. [Report (VI) on drug side effects].
Lakartidningen.
1968 May; 65(20):2047-8. doi:
NULL
. [PMID: 5725022] - B Josephson, P Furst. Sulfonamides competing with bilirubin for conjugation to albumin.
Scandinavian journal of clinical and laboratory investigation.
1966; 18(1):51-63. doi:
10.3109/00365516609065606
. [PMID: 5918673] - W Loop, E Serick. [The stability of sulfamoxoles in fluid substance and in aqueous solution].
Chemotherapy.
1966; 11(1):27-42. doi:
10.1159/000220435
. [PMID: 5957160] - J PETERSEN, G ARNHOLM. [EXAMINATION OF SULFUNO IN SERUM AND ITS EXCRETION IN BILE].
Ugeskrift for laeger.
1965 Feb; 127(?):248-52. doi:
NULL
. [PMID: 14307946] - E Serick, W Loop. The stability of sulfamoxole in serum and urine.
Chemotherapy.
1965 196; 10(2):74-8. doi:
10.1159/000220396
. [PMID: 5325143] - J NATZSCHKA. [SERUM CONCENTRATION AND EXCRETION OF 2-SULFA-4,5-DIMETHYLOXAZOLE IN AN INFANT IN THE 1ST TRIMESTER].
Arzneimittel-Forschung.
1963 Nov; 13(?):963-5. doi:
NULL
. [PMID: 14210433]