meyanthic acid (BioDeep_00000397151)

Main id: BioDeep_00000018880

 

PANOMIX_OTCML-2023


代谢物信息卡片


(1R,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-1,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid

化学式: C30H48O6 (504.3450708)
中文名称: 23-羟基委陵菜酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1(C)O)C)C(=O)O
InChI: InChI=1S/C30H48O6/c1-17-9-12-30(24(34)35)14-13-27(4)18(22(30)29(17,6)36)7-8-21-25(2)15-19(32)23(33)26(3,16-31)20(25)10-11-28(21,27)5/h7,17,19-23,31-33,36H,8-16H2,1-6H3,(H,34,35)/t17-,19-,20-,21-,22-,23+,25+,26+,27-,28-,29-,30+/m1/s1

描述信息

19alpha-hydroxyasiatic acid is a pentacyclic triterpenoid that is asiatic acid substituted by a hydroxy group at position 19. It has been isolated from the leaves of Rosa laevigata. It has a role as an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid, a hydroxy monocarboxylic acid and a tetrol. It is functionally related to an asiatic acid. It derives from a hydride of an ursane.
19Alpha-Hydroxyasiatic Acid is a natural product found in Pyracantha coccinea, Polylepis besseri, and other organisms with data available.
A pentacyclic triterpenoid that is asiatic acid substituted by a hydroxy group at position 19. It has been isolated from the leaves of Rosa laevigata.

同义名列表

12 个代谢物同义名

(1R,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-1,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; (2alpha,3beta)-2,3,19,23-tetrahydroxyurs-12-en-28-oic acid; (2a,3b,4a)-2,3,19,23-Tetrahydroxyurs-12-en-28-oic acid; 23-Hydroxytormentic acid, >=95\\% (LC/MS-ELSD); 19 alpha-Hydroxyasiatic acid; 19Alpha-Hydroxyasiatic Acid; Niga-ichigoside F1 aglycone; 19|A-Hydroxyasiatic acid; 19??-Hydroxyasiatic acid; 23-hydroxytormentic acid; 19α-Hydroxyasiatic acid; meyanthic acid



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yamin Wang, Fengrong Liu, Peng Liu. 23-Hydroxytormentic acid reduces cerebral ischemia/reperfusion damage in rats through anti-apoptotic, antioxidant, and anti-inflammatory mechanisms. Naunyn-Schmiedeberg's archives of pharmacology. 2021 05; 394(5):1045-1054. doi: 10.1007/s00210-020-02038-2. [PMID: 33394135]
  • Min Yan, Yan Zhu, Hong-Jun Zhang, Wei-Hua Jiao, Bing-Nan Han, Zhao-Xi Liu, Feng Qiu, Wan-Sheng Chen, Hou-Wen Lin. Anti-inflammatory secondary metabolites from the leaves of Rosa laevigata. Bioorganic & medicinal chemistry. 2013 Jun; 21(11):3290-7. doi: 10.1016/j.bmc.2013.03.018. [PMID: 23632365]
  • Na Zeng, Yang Shen, Ling-Zhi Li, Wei-Hua Jiao, Pin-Yi Gao, Shao-Jiang Song, Wan-Sheng Chen, Hou-Wen Lin. Anti-inflammatory triterpenes from the leaves of Rosa laevigata. Journal of natural products. 2011 Apr; 74(4):732-8. doi: 10.1021/np1007922. [PMID: 21384845]
  • Yang-Hee Kim, Jung-Hye Choi, Hong-Kun Rim, Hyun-Jun Kang, Sung-Goo Chang, Jae-Hoon Park, Hee-Juhn Park, Jong-Won Choi, Soo-Dong Kim, Kyung-Tae Lee. 23-Hydroxytormentic acid and niga-ichgoside f₁ isolated from Rubus coreanus attenuate cisplatin-induced cytotoxicity by reducing oxidative stress in renal epithelial LLC-PK₁ cells. Biological & pharmaceutical bulletin. 2011; 34(6):906-11. doi: 10.1248/bpb.34.906. [PMID: 21628893]
  • Se-Il Sohn, Hong-Kun Rim, Yang-Hee Kim, Jung-Hye Choi, Jae-Hoon Park, Hee-Juhn Park, Jong-Won Choi, Soo-Dong Kim, Seo-Young Jeong, Kyung-Tae Lee. The ameliorative effect of 23-hydroxytormentic acid isolated from Rubus coreanus on cisplatin-induced nephrotoxicity in rats. Biological & pharmaceutical bulletin. 2011; 34(9):1508-13. doi: 10.1248/bpb.34.1508. [PMID: 21881242]
  • Wei Li, Hongwei Fu, Hong Bai, Tatsunori Sasaki, Hiroyoshi Kato, Kazuo Koike. Triterpenoid saponins from Rubus ellipticus var. obcordatus. Journal of natural products. 2009 Oct; 72(10):1755-60. doi: 10.1021/np900237a. [PMID: 19795885]
  • C L Cantrell, S G Franzblau, N H Fischer. Antimycobacterial plant terpenoids. Planta medica. 2001 Nov; 67(8):685-94. doi: 10.1055/s-2001-18365. [PMID: 11731906]
  • N De Tommasi, F De Simone, C Pizza, N Mahmood, P S Moore, C Conti, N Orsi, M L Stein. Constituents of Eriobotrya japonica. A study of their antiviral properties. Journal of natural products. 1992 Aug; 55(8):1067-73. doi: 10.1021/np50086a006. [PMID: 1279126]