7-DP-MPE-P (BioDeep_00000396921)

 

Secondary id: BioDeep_00000266753

PANOMIX_OTCML-2023


代谢物信息卡片


(2e)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]-2-propenamide

化学式: C18H19NO4 (313.1314014)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC=C(C=C1)CCNC(=O)C=CC2=CC(=C(C=C2)O)O
InChI: InChI=1S/C18H19NO4/c1-23-15-6-2-13(3-7-15)10-11-19-18(22)9-5-14-4-8-16(20)17(21)12-14/h2-9,12,20-21H,10-11H2,1H3,(H,19,22)/b9-5+

描述信息

Cuscuta propenamide 1 is an enamide obtained by the formal condensation of 4-methoxyphenylethylamine with trans-caffeic acid. It is isolated from Cuscuta reflexa and displays strong inhibitory activity against alpha-glucosidase (EC 3.2.1.20). It has a role as a metabolite and an EC 3.2.1.20 (alpha-glucosidase) inhibitor. It is an enamide, a member of catechols, a monomethoxybenzene and a secondary carboxamide. It is functionally related to a trans-caffeic acid and a 4-methoxyphenylethylamine.
Cuscuta propenamide 1 is a natural product found in Microcos paniculata, Cuscuta reflexa, and Fissistigma oldhamii with data available.
An enamide obtained by the formal condensation of 4-methoxyphenylethylamine with trans-caffeic acid. It is isolated from Cuscuta reflexa and displays strong inhibitory activity against alpha-glucosidase (EC 3.2.1.20).
N-Caffeoyl O-methyltyramine is a class of alkaloid isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase (IC50 of 103.58 μM)[1].
N-Caffeoyl O-methyltyramine is a class of alkaloid isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase (IC50 of 103.58 μM)[1].

同义名列表

12 个代谢物同义名

(2e)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]-2-propenamide; (2E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]prop-2-enamide; (E)-3-(3,4-dihydroxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]prop-2-enamide; 7-(3,4-dihydroxyphenyl)-N-((4-methoxyphenyl)ethyl)propenamide; 7-(3,4-dihydroxyphenyl)-N-[(4-methoxyphenyl)ethyl]propenamide; (E)-3-(3,4-Dihydroxyphenyl)-N-(4-methoxyphenethyl)acrylamide; 3-(3,4-Dihydroxyphenyl)-N-(4-methoxyphenethyl)acrylamide; CAFFEOYL-METHYLTYRAMINE, N-O-(SH); N-Caffeoyl-O-methyltyramine; N-Caffeoyl O-methyltyramine; Cuscuta propenamide 1; 7-DP-MPE-P



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Guangxin Sun, Michael Strebl, Maximilian Merz, Robert Blamberg, Fong-Chin Huang, Kate McGraphery, Thomas Hoffmann, Wilfried Schwab. Glucosylation of the phytoalexin N-feruloyl tyramine modulates the levels of pathogen-responsive metabolites in Nicotiana benthamiana. The Plant journal : for cell and molecular biology. 2019 10; 100(1):20-37. doi: 10.1111/tpj.14420. [PMID: 31124249]
  • Patrick C Still, Bitna Yi, Tatiana F González-Cestari, Li Pan, Ryan E Pavlovicz, Hee-Byung Chai, Tran Ngoc Ninh, Chenglong Li, Djaja Djendoel Soejarto, Dennis B McKay, A Douglas Kinghorn. Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities. Journal of natural products. 2013 Feb; 76(2):243-9. doi: 10.1021/np3007414. [PMID: 23327794]
  • Xu-Dong Hu, Yang Yang, Xiang-Gen Zhong, Xiang-Hua Zhang, Yi-Nan Zhang, Zong-Ping Zheng, Yu Zhou, Wei Tang, Yi-Fu Yang, Li-Hong Hu, Jian-Ping Zuo. Anti-inflammatory effects of Z23 on LPS-induced inflammatory responses in RAW264.7 macrophages. Journal of ethnopharmacology. 2008 Dec; 120(3):447-51. doi: 10.1016/j.jep.2008.09.026. [PMID: 18952160]
  • Xu-Dong Hu, Xiang-Gen Zhong, Xiang-Hua Zhang, Yi-Nan Zhang, Zong-Ping Zheng, Yu Zhou, Wei Tang, Yang Yang, Yi-Fu Yang, Li-Hong Hu, Jian-Ping Zuo. 7'-(3',4'-dihydroxyphenyl)-N-[(4-methoxyphenyl)ethyl]propenamide (Z23), an effective compound from the Chinese herb medicine Fissistigma oldhamii (Hemsl.) Merr, suppresses T cell-mediated immunity in vitro and in vivo. Life sciences. 2007 Dec; 81(25-26):1677-84. doi: 10.1016/j.lfs.2007.10.004. [PMID: 18022200]
  • Erum Anis, Itrat Anis, Saeed Ahmed, Ghulam Mustafa, Abdul Malik, Nighat Afza, Syed Muhammad Abdul Hai, Syed Shahzad-ul-hussan, Muhammad Iqbal Choudhary. Alpha-glucosidase inhibitory constituents from Cuscuta reflexa. Chemical & pharmaceutical bulletin. 2002 Jan; 50(1):112-4. doi: 10.1248/cpb.50.112. [PMID: 11824569]